Clinical Pharmacology Lead (Associate Director)

ROLE SUMMARY As an AI-enabled strategic scientific leader, you will partner with Oncology Research Leadership to integrate AI-driven strategies that will drive data-informed decision-making across our Oncology Research pipeline. As the AI Portfolio Lead, you will bridge cutting-edge AI/advanced analytics with deep Oncology R&D expertise to guide our portfolio strategy. Working as an individual contributor reporting into the Head, Portfolio Strategy and Program Management, you will analyze and continuously assess Oncology Research projects using AI-driven insights (predictive models, scenario simulations, competitive intelligence) and propose actionable strategies to Oncology Research Leadership. This role is science-focused and spans across discovery and preclinical stage programs, ensuring that our project teams pursue the most promising scientific approaches and mechanisms of action. Your work will directly inform pipeline prioritization and resource allocation decisions, enhancing the quality and objectivity of governance deliberations with robust data. ROLE RESPONSIBILITIES Portfolio Analysis and Insights: Continuously analyze the oncology Research portfolio (ESD through Preclinical) using advanced AI/ML tools and analytics to evaluate each program’s scientific strength, probability of success, and strategic portfolio fit per disease area strategies. Strategy Recommendation: Develop and propose data-driven portfolio strategies (at both project and portfolio levels) to senior leaders and Research governance committee. Use scenario analysis and predictive modeling to highlight optimal project prioritization, pipeline balance, and resource allocation scenarios. AI-Enabled Decision Support: Integrate AI-derived insights (e.g. machine learning predictions, knowl

Position Summary Pfizer is seeking a highly motivated Scientist to join the In Vivo Pharmacology group within the Oncology Research Unit, with a focus on antibody-drug conjugate (ADC) programs. This role supports the execution of high-quality in vivo efficacy, pharmacodynamic, tolerability, and mechanistic studies that enable preclinical ADC discovery and development. The ideal candidate will demonstrate strong technical capability in oncology animal models, careful attention to study details, and a commitment to animal welfare, compliance, and scientific rigor. The Scientist is expected to contribute as a reliable technical and scientific team member while developing increasing independence in study execution, data interpretation, and cross-functional collaboration. Position Responsibilities Execute in vivo oncology studies supporting ADC discovery programs using a variety of in vivo models including syngeneic, cell line-derived, and patient-derived xenograft models as appropriate. Perform routine and advanced in vivo procedures, including tumor measurements, body weight monitoring, test article administration, clinical observations, and sample collection. Support ADC pharmacology studies assessing efficacy, tolerability, pharmacodynamic biomarkers, dose-response relationships, schedule optimization, and combination strategies. Prepare, review, and follow study protocols, dosing schedules, randomization plans, and sample collection timelines in alignment with project goals and internal standards. Maintain accurate, timely, and compliant study records using electronic data capture systems and approved documentation practices. Coordinate with project line leads, vivarium operations, pathology, toxicology translational scientists, bioanalytical, pharmacodynamic and pharmacokinetic teams, and external partners to enable efficient study execution. Assist with data quality revie

Position Summary Pfizer is seeking a motivated Senior Associate Scientist to join the In Vivo Pharmacology group within the Oncology Research Unit, with a focus on antibody-drug conjugate (ADC) programs, but including other large molecule and small molecule programs. This role supports the execution of in vivo oncology studies that enable ADC discovery and preclinical development, including efficacy, tolerability, pharmacodynamic, and sample collection workflows. The ideal candidate will demonstrate strong technical aptitude, careful attention to detail, and a commitment to animal welfare, compliance, and high-quality study execution. The Senior Associate Scientist is expected to contribute as a dependable technical team member while building scientific understanding of oncology pharmacology and ADC-specific study requirements. Position Responsibilities Execute in vivo oncology studies supporting discovery programs using a variety of in vivo models including human cell line- derived, patient-derived xenograft, syngeneic models as appropriate with minimum guidance from study leads. Perform routine and advanced in vivo procedures, including tumor measurements, body weight monitoring, test article administration (IV, PO, subQ, IP dosing), clinical observations, and sample collection. Perform routine in vitro tissue culture procedures Support pharmacology studies evaluating efficacy, tolerability, pharmacodynamic biomarkers, dosing schedules, and combination approaches. Prepare study materials, confirm dosing and sampling schedules, and ensure study activities are performed according to approved protocols and SOPs. Maintain accurate, timely, and compliant study records using approved electronic data capture and documentation systems. Communicate study observations, technical issues, animal welfare concerns, and timeline risks promptly to managers and study line leads. Collabo

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Key Responsibilities Provide clinical and scientific leadership for one or more inflammation development programs. Develop and continually refine the Clinical Development Plan (CDP), including indication strategy, target populations, clinical sequencing, success criteria, and key development decisions. Lead the design and execution of early- and mid-stage clinical trials, including Phase 1b/2 proof-of-concept and dose-ranging studies. Translate complex immunology and human disease biology into testable clinical hypotheses and development strategy. Integrate clinical, translational, biomarker, pharmacologic, and comp

ROLE SUMMARY The Clinician Medical Monitor is accountable for providing medical and scientific expertise and oversight for Clinical Trials and serves as a single point of accountability for design, execution, monitoring, delivery and reporting of one or more clinical studies and to ensure patient safety. The clinician medical monitor may be required to design a development strategy for multiple protocols designed to obtain worldwide approval for a compound or group of compounds. In addition to study level activities, the clinician medical monitor may participate in standing committees, review compounds for potential in-licensing, including performance of due diligence reviews, and aid new business development on market opportunities and the target product profile. ROLE RESPONSIBILITIES Accountable for safety across the study Provide study team with medical advice for all medical issues during risk assessment and mitigation planning to enable quality, compliance and patient safety at the trial, site and patient level. Ensures development of and adherence to the Safety Surveillance Review Plan (SSRP). Consistent with the SSRP, performs and documents regular review of individual subject safety data, and performs review of cumulative safety data with the safety risk lead. As appropriate, the clinician medical monitor may delegate these responsibilities to the study clinician scientist identified in the SSRP. The specific components of safety data review are detailed in the appropriate SOPs and the “Safety Data Review Guide – for Clinicians.” Monitor study safety issues and provide input to serious adverse events (SAEs) reports. Provides appropriate medical context in terms of risk factors, medical history and other important medical factors required to put the SAE or AE into appropriate medical context required for benefit-risk assessm

Job Title Clinical Solution Specialist (Patient Monitoring) – Lexington, KY Job Description Clinical Solution Specialist - Lexington, KY with travel throughout the Central Zone Bring your passion for patient care and technology to this role where you’ll be responsible for providing clinical customer support as the clinical application knowledge expert. You’ll facilitate solutions design, optimization, configuration, and delivery of Philips Hospital Patient Monitoring (HPM) products to ensure a quality customer experience. Your role: Serving as a clinical resource to Philips HPM customers, working closely with the field service, sales, and project management organizations throughout a multiphase implementation and go-live process – establishing and maintaining strong working relationships with key internal partners and customers to enable a successful implementation team. Understanding customer goals and developing plans to support clinical solutions implementation and usage – delivering clinical services to customers that are consultative, advanced, and focused on workflows and optimization. Managing the clinical aspects of an implementation to include assessing workflows, evaluating education needs, creating education plans, determining custom configurations requirements, planning and delivering equipment and application education, supporting first customer use, encouraging ongoing adoption of change, and optimizing use of complex monitoring solutions. Understanding the clinical implications of technical implementations (including networks and clinical informatics systems); applying product and clinical knowledge to troubleshoot and solve problems. Approximately 90% travel across the Central district is required. The average driving time is 1-4 hours daily. Occasional overnight stays and travel by air/train/bus may be required. Fur