What you’ll do Partner with medical image reconstruction scientists / engineers to build ML components that improve reconstruction quality, speed, robustness, or quantitative accuracy. Define training/evaluation pipelines, datasets, and metrics that map to user needs and design requirements. Productionize models: inference performance, reproducibility, monitoring for drift/regressions, and safe fallbacks. Collaborate on hybrid algorithms, incorporating physics and learned priors, denoisers, learned regularizers, and quality estimation. Help build tooling for rapid experimentation as well as rigorous verification of algorithm changes. What we’re looking for Strong applied ML experience plus comfort with signal processing / imaging or adjacent domains. Ability to move fluidly between research prototypes and production-quality systems. Strong evaluation discipline: metrics, ablations, data leakage avoidance, and reproducibility. A demonstrated track record of applying ML to physics-based or inverse problems (i.e., shipped projects, a portfolio, or publications.) Useful experience ML for imaging/inverse problems (or adjacent) with strong evaluation discipline and comfort with GPU performance constraints. Pragmatic production mindset: reproducible training/inference, regression testing, and safe deployment in high-stakes contexts. A background in computational physics or scientific computing. Leverage ML-based methods such as PiNNs and Neural Operators to solve partial differential equations arising in ultrasound simulation and imaging. Experience in Agentic-SciML is a plus. Hands-on experience with data curation for ML: building datasets from messy, real-world sources, defining ground truth, and managing labeling or simulation pipelines. Background in data assimilation: combining observations with physics-based models (Kalman filtering, variational methods, ensemble approaches, or learned variants).
Jobs in United States
Principal Applied Ai Ml Scientist in United States
334 active opportunities · Updated October 2026
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Explore current principal applied ai ml scientist jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. The Product Security team ensures that Snowflake products are built and shipped with the highest level of security. Our team drives the security posture of Snowflake products and is responsible for embedding security into every stage of the product lifecycle, from design through deployment and beyond. We design and build frameworks, systems and services that keep Snowflake secure. As a Principal Software Engineer II on the Product Security team, you will be the senior technical authority for Product Security and play a critical leadership role in shaping and advancing Snowflake’s security. This is a unique opportunity to define and influence our long-term security strategy and have a direct impact on the security of the Snowflake platform and the trust of our customers. You will operate across organizational boundaries, guiding major security initiatives, influencing architectural decisions at the highest levels, setting the technical direction for the organization, and ensuring consistent security excellence across all product teams while working closely with business leaders to advance Snowflake’s business. The role requires deep expertise in security, software engineering, distributed systems, software infrastructure, AI/ML, applied cryptography, threat modeling and clou
Become a part of our caring community Every large organization is making critical decisions today about how it will leverage AI over the next decade. Few have leaders who can both define that vision and demonstrate its viability through hands-on engineering. This role requires both. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations to source documents, and route difficult cases to human experts. These capabilities support decisions that impact real healthcare outcomes for members. As a Principal AI Applied Engineer, you will define the technical strategy, architectural standards, and long-term vision for AI-enabled products across the organization. You will influence enterprise-wide decisions regarding AI platforms, model strategies, engineering standards, and technology investments while remaining deeply hands-on in prototyping, experimentation, architecture, and software development. This is the highest-level individual contributor role within the AI Applied Engineering organization. Success requires exceptional technical depth, organizational influence, strategic thinking, and the ability to translate emerging AI capabilities into scalable, reliable, and responsible production systems. Why Join Us Shape the long-term AI architecture and engineering direction for a large enterprise healthcare organization. Influence how AI-enabled products are designed, built, evaluated, deployed, and governed across multiple teams. Drive strategic decisions involving models, vendors, platforms, infrastructure, and shared capabilities. Prototype and validate emerging technologies before the organization invests at scale.</
About the Team Enterprise Verticals builds role-specific ChatGPT Work experiences for high-value enterprise workflows. We combine product engineering, plugins and skills, connectors, data, evaluations, and customer evidence to turn useful demos into reliable daily work. This opening sits within the Technology vertical inside Enterprise Verticals. The group focuses on repeatable workflows for people at technology companies, beginning with functions such as data and analytics, sales, and design, and carries the shared platform needs—tool integration, permissions, quality measurement, and safe rollout—across those experiences. We work closely with Design, Research, GTM, Security, and platform teams, as well as with customers and design partners. Success means that people can reach a trustworthy first result, understand what the system did, and keep using the workflow—not merely that a prototype exists. About the Role We are looking for an exceptionally experienced, hands-on full-stack engineer to define and build the next generation of AI-powered enterprise workflows. You will take on the hardest and most ambiguous problems in the Technology vertical: translating real customer needs into product direction, designing the systems behind the experience, and personally writing and shipping production-quality code across the stack. You will own the technical direction and end-to-end delivery of products spanning ChatGPT Work surfaces, backend services, plugins, connectors, enterprise data, permissions, and evaluations. You will make foundational architecture and product tradeoffs; establish patterns other engineers can build on; and hold these experiences to a high bar for reliability, security, observability, and customer value. This is an individual-contributor role for an engineer who leads through technical judgment, direct execution, and influence—not people management. You should be equally comfortable working directly with customers, setting direction with senior cro
About the Team Our Cyber team builds AI systems and products that help trusted defenders understand and respond to cyber threats while improving the safety and reliability of frontier models in security-sensitive settings. The team works across product engineering, model training, evaluations, safeguards, and deployment to make advanced cyber capabilities useful to defenders and responsibly managed. We collaborate closely with Safety/Preparedness, Research, Security, Legal, Communications, GTM, and external partners across OpenAI’s broader cyber work. About the Role We’re looking for research and software engineers to join Codex Cyber. You’ll help define and ship security products, work with trusted defenders and customers, shape model training and access patterns, and build research and evaluation systems for assessing cyber capabilities, validating safeguards, and improving training data. This role is hands-on and cross-functional, connecting product launches, model development, safety work, and real-world security use cases. In this role, you will: Help define and execute the technical roadmap for Codex Cyber’s security products, including evaluations, safeguards, trusted-defender workflows, and deployment decisions. Work with trusted defenders, customers, and partner teams to understand cyber use cases, evaluate risk, and turn feedback into product and research priorities. Shape cyber-specific model training and access patterns, including data, evaluations, validation, and deployment criteria. Build and validate systems for measuring cyber capabilities, monitoring misuse risk, and proving safeguards work in practice. Collaborate with Safety/Preparedness, Research, Security, Legal, Communications, Go-to-Market, and external partners on company-wide cyber priorities. Translate frontier cyber research into launch-ready tools, operational playbooks, and durable infrastructure for Codex and security products. You might thrive in this role if you: Enjoy 0 -> 1 envi
About the Team OpenAI's research training infrastructure powers how our frontier models are trained and evaluated. The Simulation team sits at the intersection between the agentic harness that powers OpenAI's products and the research infrastructure where GPT-next is trained, ensuring that our model's training environment is as realistic as possible. This team owns the integration layer that connects our production harness capabilities into the training stack. The work is highly cross-functional and high leverage: researchers depend on it to run experiments and evaluations reliably as well as to develop the next generation of harness capabilities. Failures in this surface can materially affect training velocity and correctness. About the Role We're looking for a Principal Software Engineer to lead the architecture and evolution of the Simulation Platform. You'll own a critical interface between research and engineering, building the systems, APIs, and operational patterns that let researchers use agentic coding infrastructure safely and effectively in training environments. This role is ideal for a senior backend or infrastructure engineer with strong technical judgment, product sense for highly technical users, and the ability to drive execution across multiple teams. The highest-leverage work is building robust infrastructure that supports and accelerates research without compromising engineering quality. In this role, you will Design, build, and evolve the integration between the Codex harness that powers OpenAI's products and research training infrastructure used for training GPT-next Build a platform for our LLMs to train and be evaluated in simulated environments that mimic their deployment setting as closely as possible, on every axis: agentic harness, compute substrate, timing, tools, data sources, humans in the loop, and more Own major integration surfaces end-to-end, from architecture and API design through rollout, operations, and long-term maintenance Bu
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake's Data Engineering organization builds the platform that ingests, transforms, and stores data for modern lakehouse architectures — powering billions of queries, DML, and DDL operations with industry-leading price-performance. We lead the industry's shift to open data lakes through our work on Iceberg and Polaris, and we deliver capabilities like Snowpark, Dynamic Tables, cross-region replication, time travel, and zero-copy cloning at enterprise scale. We are investing in a new line of applied research — building toward verified data infrastructure and trustworthy data systems — that brings formal methods, automated reasoning, and modern AI techniques to bear on the hardest problems in our distributed systems and developer tooling. The goal is to improve correctness, reliability, and engineering velocity at a scale very few platforms operate at. We're hiring at both the Staff and Principal level; we'll calibrate the offer to the candidate's experience and scope of impact. What you'll do Lead research projects that apply formal methods, program analysis, automated reasoning, and AI-driven techniques (including code generation and modeling) to real problems in our cloud data platform. Translate research ideas into prototypes, then into shipped capabilities that move
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Data Engineering - Applied Field Engineer- CA- Menlo Park- Remote Snowflake is about empowering enterprises to achieve their full potential — and people too. With a culture that’s all in on impact, innovation, and collaboration, Snowflake is the sweet spot for building big, moving fast, and taking technology — and careers — to the next level. Our Solution Engineering organization is seeking a Data Engineering Specialist to join our Applied Field Engineering team who can provide technical leadership in working with both technical and business executives in the design and architecture of the Snowflake Cloud Data Platform as a critical component of their enterprise data architecture and overall ecosystem. In this role you will work directly with the sales team to understand the needs of our customers, strategize on how to navigate winning sales cycles, provide compelling value-based demonstrations, support enterprise Proof of Concepts, and ultimately close business. You will leverage your expertise, best practices and reference architectures highlighting Snowflake’s Data Platform capabilities across data ingestion, transformation, and lakehouse workloads. You are equally comfortable in both a business and technical context, interacting with executives and talking shop with tec
At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are a visionary and innovative industry expert team with a track record of architecting, building, and taking solutions to market applicable to various sub-verticals across financial services, spanning retail and commercial banking, lending and payments. There is only one Data Cloud. Snowflake's founders started from scratch and designed a data platform built for the cloud that is effective, affordable, and accessible to all data users. But it didn't stop there. They engineered Snowflake to power the Data Cloud, where thousands of organizations unlock the value of their data with near-unlimited scale, concurrency, and performance. This is our vision: a world with endless insights to tackle the challenges and opportunities of today and reveal the possibilities of tomorrow. Are you passionate about taking new ideas and innovation to market? Have you successfully applied technology to solve business problems in core banking? If so, we have a strategic opportunity to use your expertise across Data, Cloud, and AI to drive transformational changes across the financial services industry in a highly visible role collaborating with internal and external leadership. Snowflake is seeking a seasoned Financial Services Industry Architect with deep, hands-on experience designing and d
About the Team Tax and Trade at OpenAI shapes business strategy by embedding critical tax, export control, customs, and cross-border considerations into how the company builds, sources, scales, and operates in support of the mission. We combine deep expertise with practical systems thinking to look around corners, identify emerging risks and opportunities early, and help teams make smarter decisions at the point where strategy becomes execution. Across procurement, hardware operations, manufacturing, logistics, finance, legal, supplier onboarding, and operator workflows, we build robust, scalable support services leveraging cutting-edge technology—including governed AI and automation—to make complex regulated work more durable, more efficient, and easier to scale. About the Role We’re hiring a Senior Manager, Export Controls to lead OpenAI’s export controls strategy and operating model. This is a senior role with broad scope across advanced computing, semiconductors, software, hardware, manufacturing, and high technology partnerships. You will refine how OpenAI classifies controlled technology, software, and hardware, structures access-controlled environments, manages licensing and supplier commitments, and scales export-control operations in a way that supports the company’s pace of innovation. You will also shape how OpenAI applies AI and agentic workflows to policy-heavy operational work, building systems that make complex rules easier to navigate and easier to execute. In this role, you will: Refine the strategy and operating model for OpenAI’s export controls program across advanced computing, semiconductors, software, hardware, manufacturing, and high technology partnerships. Own export classification and licensing strategy for controlled technical data, software, hardware, and research environments. Lead the design and operation of compliant controlled environments and related governance processes. Partner with Research and Infrastructure to support efficient
Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. Micron's Global Supplier Quality organization is seeking a Controller Quality Principal Engineer to lead the quality strategy, qualification, and continuous improvement of storage and memory controller (ASIC/SoC) manufacturers supporting Micron's SSD, embedded, and storage solutions portfolio. This is a senior technical leadership role responsible for driving controller supplier quality performance from design qualification through mass production and field support The successful candidate will collaborate across functions with ASIC Development Team, Compose Engineering, Product Engineering, Dependability, Manufacturing, and Commodity Management, as well as directly with controller IC vendors, foundries, third party reliability labs and OSAT (outsourced assembly and test) partners, to ensure controller quality, reliability, and supply continuity meet Micron's standards. This role can be based in Taiwan, Hyderabad, or San Jose and will work extensively across time zones with global partners and suppliers! Develops, evaluates, revises, and applies technical quality assurance protocols/methods to inspect and test in-process raw materials, production equipment, and finished products. Ensures activities and items are in compliance with both company quality assurance standards and applicable government regulations. Performs analysis and identifies trends in the inspection of finished products, in-process materials and bulk raw materials, and recommends corrective actions when vital. Ensures that established manufacturing inspection, sampling and statisti
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: The Staff Data Engineer is a senior, hands-on technical contributor within an Enterprise Data domain, owning technical design and the most complex implementation work for assigned data products, capabilities, and integrations. The role establishes, communicates, and evolves the technical approach for the work it leads and is accountable for the quality, durability, and supportability of the solutions it shapes. Staff Data Engineers work directly with business stakeholders to understand needs and shape technical solutions, engaging at a level appropriate to the work they lead. The role is expected to be fluent in both technical execution and business context, translating between them without losing precision in either. The Staff Data Engineer sets technical direction for assigned capabilities and initiatives within the domain, applies enterprise standards and platform patterns, engages Principal Engineers where cross-domain considerations apply, and multiplies the effectiveness of the domain team through design leadership, code review, and mentoring. This role is based in Madison, WI . Essential Duties Include, but are not limited to, the following: Technical design and solutioning Own technical design and hands-on delivery for the most complex or highest-risk work across assigned data products, capabilities, and initiatives, including data models, pipeline architecture, integration patterns, and platform usage decisions. Produce design docume
Brief Description of the Organization Citi, the leading global bank, has approximately 200 million customer accounts and does business in more than 160 countries and jurisdictions. Our mission is to serve as a trusted partner to our clients by responsibly providing financial services that enable growth and economic progress. We strive to earn and maintain our clients’ and the public’s trust by constantly adhering to the highest ethical standards and making a positive impact on the communities we serve. Citi’s Personal Banking and Wealth Management (PBWM) division is building a purpose-driven team to serve its globally diverse, digitally forward customers in top cities around the world. We’re looking for exceptional candidates who think digitally and differently, resolve problems in unconventional ways and strive to provide a remarkable experience for our clients. We define success by our Citi Leadership Principles: We Take Ownership, We Deliver with Pride and We Succeed Together. Overview of the Role The Head of USCC Personal Loans Core Platforms and Lending Integrations is accountable for the execution and delivery of next-generation API integration platforms across value proposition, lending, and commerce ecosystems. This role owns a critical engineering function responsible for building scalable, secure, and compliant integration platforms that support Value Cards, Lending and Commerce business in USCC. The individual applies deep technical expertise and strong business understanding to translate strategic priorities into enterprise-grade API integration solutions. This is a highly technical leadership role, requiring the individual to actively drive architecture, influence low-level design, and guide implementation through principal and senior engineers. The role is expected to set engineering standards, define technical guardrails, and contribute hands-on where required, including the ability to review, prot
About the team The Agent Enablement AI Deployment Engineering (ADE) team works across engineering, product, design, partnerships, and strategic customers to grow an open ecosystem of agent-enabled sites and services. We help partners adopt the OpenAI tech stack related to identity, permissioning, agent-auth primitives so users can safely connect ChatGPT and Codex to the tools, services, and workflows they already use. Our team also works with external partners on defining the standards for agent access, marketplace offerings as well as other agent enablement initiatives to ensure users of ChatGPT and Codex go from intent to task completion seamlessly. About the role We are looking for an AI Deployment Engineer to help strategic partners design, build, validate, launch, and operate agent enablement integrations across web applications, connectors, APIs, CLIs, MCP servers, and developer tools. This is a hands-on, partner-facing product engineering role for someone who can contribute to the platform itself, lead sophisticated technical engagements, and turn ambiguous identity and agent-workflow requirements into secure, production-ready integrations. You will work across partner product and engineering teams and OpenAI’s product, engineering, design, partnerships, legal, policy, security, support, and go-to-market teams. You will identify high-value user journeys, choose the right integration path, prototype and review architectures, write code, run evaluations and dogfood, trace failures end to end, guide launch and rollout, and support post-launch iteration. The best person for this role moves fluidly between full-stack code, OAuth/OIDC and identity systems, product judgment, project leadership, and clear communication with engineers and executives. This role is a fit for a product-minded engineer who wants to stay close to users and partners while going deep on authentication, permissions, reliability, safety, and developer experience. The principle objective is to
This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your Role at Baxter As a Principal Software Engineer, you will play a crucial role in designing, developing, and maintaining software applications using the .NET framework. You will work closely with cross-functional teams to deliver high-quality solutions that meet our clients’ needs. This position requires strong technical expertise, problem-solving skills, and a passion for continuous learning. What You'll Do: Design, develop, test, and maintain scalable applications and services using C# and the .NET framework. Collaborate with product managers, architects, developers, and stakeholders to define technical requirements and solution designs. Develop and maintain RESTful APIs and GraphQL services that support modern application and integration needs. Write clean, maintainable, and high-quality code following established software engineering principle
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