Jobs in United States

Safety Manager in United States

5,840 active opportunities · Updated October 2026

Explore current safety manager jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 Remote Based, United States· Remote
✓ High-confidence listingCompany trend +26.9%

$133K – $212K/yr

Quick readStrong listing-quality and freshness signals

Job Title Medical Safety Manager - Ultrasound Job Description Medical Safety Manager, Ultrasound The Medical Safety Manager independently oversees safety surveillance activities for medical products by analyzing data from post-marketing surveillance, literature reviews, and real-world evidence to identify risks and ensure patient well-being. The role supports regulatory compliance through the preparation of safety-related documentation, including Risk-Benefit Analyses, protocols, Clinical Study Reports, and Clinical Evaluation Reports. Your role: Independently conducts comprehensive safety evaluations using data from post-marketing surveillance, literature reviews, and clinical trials to proactively identify and assess potential risks and safety signals. Provides critical safety insights and recommendations for risk management activities, including Health Hazard Evaluations, Risk-Benefit Analyses, and recall procedures, ensuring robust patient safety measures are in place. Supports New Product Introduction, clinical studies, and post-marketing efforts by delivering safety-related perspectives and collaborating on safety inputs for regulatory submissions and key documentation such as RBAs, protocols, Clinical Study Reports, and Clinical Evaluation Reports. Responds to safety-related inquiries from healthcare professionals, patients, and internal stakeholders, fostering trust through transparent communication and supporting the implementation of safety policies, procedures, and programs to promote a culture of compliance. Stays current with evolving medical product safety regulations and guidelines, offering input into the design and execution of safety studies and vigilance activities to ensure adherence to requirements throughout the product lifecycle. You're the right fit if: You’ve acquired 5&#43

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📍 Remote Based, United States· Remote
✓ Quality checkedCompany trend -100%

$133K – $212K/yr

Job Title Medical Safety Manager, Hospital Patient Monitoring Job Description Medical Safety Manager, HPM The Medical Safety Manager, Hospital Patient Monitoring is responsible for conducting comprehensive evaluations of safety information sourced form a variety of channels such as Post-Marketing Surveillance (PMS) and literature searches, working under limited supervision. Your role: Provides essential support in bolstering patient safety by actively contributing insights and recommendations to critical processes such as Risk Management, Health Hazard Evaluations (HHE), Risk-Benefit analyses, and recall procedures. Offers valuable assistance in delivering safety-related perspectives for New Product Introduction (NPI) projects, clinical studies, and Post-Marketing Surveillance (PMS) efforts, facilitating informed decision-making. Collaborates effectively to furnish pertinent safety inputs for regulatory submissions and key documents such as Risk-Benefit Analyses (RBA), protocols, Clinical Study Reports (CSR), and Clinical Evaluation Reports (CERs), ensuring compliance and transparency in safety evaluations. Conducts literature reviews and surveillance activities to identify emerging safety issues, ensuring proactive identification and mitigation of potential risks. Provides answers to safety-related inquiries from healthcare professionals, patients, and internal stakeholders, fostering trust and transparency in communication regarding product safety. Contributes to the implementation of safety-related policies, procedures, and programs to promote a culture of safety and compliance within the organization. Maintains awareness of evolving regulations and guidelines related to medical product safety and ensures compliance with applicable requirements. Provides input into the design and conduct of safety studies and medical device vigil

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. About the Role The Safety Measurement Product Manager owns OpenAI's approach to measuring harm and safeguard efficacy in production, including driving the strategy for our suite of safety measurement platforms and products used across the company. You will partner closely with our safety research and engineering teams to determine what we measure, where we measure it, and how we measure it, feeding those insights directly into critical leadership decisions and back into our safety work. You will also represent the company's topline safety metric as well as prioritize incoming requests from partner teams to expand our safety measurement platform to more use cases. This position is based in San Francisco, CA, with relocation assistance available. In this role, you will: Partner closely with data science, research, engineering, policy teams, and other stakeholders to craft a vision for understanding safety outcomes and prevalence on our platforms. Define strategic priorities and product roadmaps focused on improving safety measurement approaches will scaling our measurement platform to more use cases, products, and cross-functional team needs. Establish repeatable processes to integrate cutting-edge AI safety research into OpenAI’s safety m

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $345K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences – all created by our global community of developers and creators. At Roblox, we're building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We're on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you'll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Why Safety AI Systems? As Senior Engineering Manager for Safety AI Systems at Roblox, you'll lead technical efforts and manage a team of experienced engineers to develop innovative AI solutions for language and text content safety. You'll oversee machine learning systems, data quality, training pipelines, and model performance to address challenges like real-time content understanding across Roblox's experiences

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $295.3K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Why Safety AI Systems? As Senior Engineering Manager for Safety AI Systems at Roblox, you'll lead technical efforts and manage a team of experienced engineers to develop innovative AI solutions for multimodal content safety. You’ll oversee machine learning systems, constructing multimodal model architectures, improving data quality, training pipelines, and model performance to address challenges like real-time multi-verse content understanding and advanced moderation with large vision language models, spanning avatars, images, videos, audios, text, code / data models, and their composites. In close collaboration with product, policy, and Trust & Safety teams, you'll design large-scale systems to detect and mitigate abusive behavior before it harms the community. You'll own critical services at massive scale, balancing user freedom with platform civility to protect and empower our users. Your leadership will help ensure Roblox remains a safe, inclusive space for self-expression and shared experiences. You Will Own the vision, technical direction, and execution of machine learning solutions for the Multimodal Safety AI system, ensuring these systems effectively detect and prevent ha

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. Within Safety Systems, the Model Policy team works to ensure that frontier models behave safely and reliably in real-world environments by designing policies that define safe model behavior. Our relevant publications include: Safety at every step OpenAI GPT6 System Card OpenAI Model Spec GPT-Live ChatGPT Images 2.5 About the Role We are hiring a Model Policy Manager to focus on the safety of multimodal models. In this role, you will shape how OpenAI identifies, evaluates, and addresses risks in multimodal AI models - such as GPT-Live and ChatGPT Images - as well as multimodal capabilities in frontier AI models. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Design and maintain model policies for audio, image, video, and omni-modal behavior. Translate theories of harm and threat models into behavioral safety policies, evaluation criteria, grading guidance, and safeguards. Identify and analyze safety regressions and failure patterns to identify gaps in existing policies and inform policy iteration. Develop policy artifacts that support model training, evaluation, and deployment, including behavior i

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📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. Within Safety Systems, the Model Policy team works to ensure that increasingly capable models behave safely and reliably in real-world environments. We investigate emerging model failures, define the behavior models should exhibit instead, and develop the data, evaluations, monitoring, and safeguards needed to improve and validate that behavior. Our work connects alignment research with the practical challenges of training and deploying frontier models. About the Role In this role, you will shape how OpenAI understands and addresses real-world risks that emerge from model misalignment as models become more autonomous and operate over longer horizons. You will investigate how misaligned behavior emerges across extended trajectories - including when models persist toward the wrong objective, take unsafe shortcuts, lose track of instructions, exploit weaknesses in their environment, or circumvent constraints - and translate these insights into behavioral policies, evaluations, monitoring, and safeguards. This role is ideal for someone who wants to turn alignment and safety concerns into concrete, empirically grounded improvements to frontier AI systems. Your Responsibilities: Identify vulnerabilities that emerge as models interact with tools, data, and external systems, and translate them into model- and system-level safeguards. Develop threat models and empirical frameworks for understanding harmful outcomes from misaligned behavior. Build frameworks for understanding harmful outcomes arising from model misalignment. Identify the underlying behaviors and system conditions that drive those outcomes. Turn findings into policy frameworks, evaluation criteria, online measurement and safeguards. Develop human data campaigns and gold sets to ground measurement and evaluation of eme

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. About the Role We are hiring a Product Manager to focus on risk related to multimodal models. In this role, you will drive initiatives which ensure that OpenAI’s audio, image, and video deployments are safe, impactful, and aligned with user needs and technical innovation. You will clarify strategic priorities, develop safety-focused product roadmaps, and collaborate closely with AI researchers, software engineers, policy experts, and cross-functional partners. This role suits a proactive, technically skilled product manager adept at adversarial thinking and excited to tackle challenging, ambiguous problems through structured analysis and collaborative decision-making. This position is based in San Francisco, CA, with relocation assistance available. In this role, you will: Partner closely with AI research, engineering, data science, policy teams, and other stakeholders to embed safety throughout the development and deployment of multimodal AI models - such as GPT-Live and ChatGPT Images - as well as multimodal capabilities in frontier AI models. Develop comprehensive frameworks for understanding and mitigating deployment safety risks, drawing on data analysis, expert consultation, and adversarial assessments. Define strate

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📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -85.6%

From $164.7K/yr

Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . As a Staff Product Manager for the GenAI Safety team within Trust & Safety, you'll define and drive the product strategy for ensuring Pinterest's GenAI-powered systems are safe, fair, and trustworthy. You'll be responsible for building proactive safety frameworks that scale with our growing AI capabilities, partnering deeply with engineering, policy, data science, and design to protect our users while enabling Pinterest to innovate responsibly. This is a high-impact role for someone who is passionate about the intersection of AI and user safety, and who thrives in ambiguous, fast-evolving problem spaces. You'll work at the frontier of responsible AI - anticipating novel harms before they emerge, red-teaming new AI features, and translating complex policy goals into measurable product requirements. What you'll do: GenAI Safety Strategy: Own a

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📍 California, United States
✓ High-confidence listingCompany trend +190.5%
Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description The Senior Manager, Kite Safety and Pharmacovigilance provides scientific and strategic leadership for pharmacovigilance activities supporting Kite’s investigational and marketed products. This role serves as a senior pharmacovigilance science expert, leading complex safety analyses, regulatory deliverables, and cross-functional safety strategy execution. Key Responsibilities Aggregate Reporting and Medical Writing Serve as lead author for complex aggregate safety reports, including PSURs, PBRERs, and DSURs, synthesizing global safety data and clinical context Author and review high-impact safety documents supporting regulatory submissions and lifecycle management Safety Analysis and Signal Management <

Recruitment
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Safely delivering increasingly capable AI systems requires scalable technical safeguards, clear ownership of emerging risks, rigorous deployment readiness, and close coordination across research, engineering, product, operations, legal, policy, and external partners. Our Technical Program Managers lead complex, high-stakes initiatives that turn safety commitments into deployed systems and measurable outcomes. We work across model development, infrastructure, product, and operational response to help ensure our technology is deployed responsibly and cannot be used to cause serious real-world harm. About the Role We’re seeking Technical Program Managers to drive complex product, platform, and safety initiatives across ChatGPT, API, enterprise, and related deployment environments. These roles operate at the intersection of technical strategy and execution: you will turn safety and product priorities into actionable plans, influence architectural and operational decisions, and deliver durable capabilities across model, infrastructure, application, and platform layers. Depending on the role, you may enable sensitive or high-impact model deployments, integrate safeguards into cloud and API platforms, prevent violent misuse and other serious harms, improve detection and enforcement systems, create platform solutions for safety or establish new programs as risks evolve. You will partner deeply with engineers, researchers, product managers, and operational teams while communicating technical tradeoffs and program decisions to senior leadership. You bring technical fluency, product judgment, and a strong execution record. You’re comfortable navigating ambiguity, advocating for users and developers, balancing safety with model usefulness, and leading cross-functional work with urgency, rigor, and empathy. Specific focus areas and scope will vary by opening and level. Thi

AWSRestMachine LearningAI
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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $345K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Senior Engineering Manager, Safety Platform You will lead engineering pods within the Safety Platform organization, driving the technical vision and execution for the foundational systems that power every safety workflow at Roblox. You will own the core safety platform end-to-end: from the shared infrastructure and APIs that enable trust & safety capabilities across the company, to the tooling ecosystem that empowers internal operators to investigate, intervene, and resolve issues at scale. The scope also includes the Safety agentic platform — AI-powered systems that automate and augment safety workflows across detection, enforcement, and review pipelines. As the platform layer beneath every safety surface, your work will define how quickly and reliably Roblox can respond to emerging threats. This role requires a leader with a strong platform mindset who can balance technical rigor with broad organizational impact — working across User Safety, Trust & Safety Policy, Data Science, and Machine Learning to deliver scalable, extensible, and high-availability systems for one of the world's largest platforms. You Will: Lead and Develop: Recruit, hire, mentor, and inspire a diverse team of

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📍 United States· Full-time· Remote
✓ High-confidence listing

$220K – $275K/yr

Quick readStrong listing-quality and freshness signals

Discord has a highly engaged community of millions of daily active users who use the platform for many different reasons, but there’s one thing that nearly everyone does: play video games. Discord plays a uniquely important role in the future of gaming, and we are focused on making it easier and more fun for people to hang out before, during, and after playing games. Discord exists to give people the power to create space to find belonging — to talk regularly with the people they care about and build genuine relationships with friends and communities close to home or around the world. We're looking for an Analytics Manager to lead our Scaled Abuse Countermeasures and Research (SCAR) team — the team that safeguards Discord’s platform integrity. SCAR detects, analyzes, and disrupts high-volume threats through a combination of automated systems, deep research, and active incident response. This role reports to the Head of Safety Intelligence and Automation. What You'll Be Doing Lead and mentor a team of data analysts, scientists, and researchers who investigate active threats, identify platform abuse vectors, and uncover adversarial patterns. Define a strategic roadmap that prioritizes and disrupts the highest impact abuse operations through structured research, rigorous analyses, and live experimentation. Collaborate closely with the safety machine learning team to improve models by identifying the threat signals that translate into long-term, automated countermeasures. Partner cross-functionally with Product, Engineering, Data Science, Policy, Legal, and Revenue, influencing safety-by-design decisions upstream of abuse. Influence capacity toward high-impact infrastructure, such as automated rule engines, ML models, or agent moderation tools. What you should have 2+ years of people management experience leading technical teams, including engineers, data scientists, analysts, applied researchers, or equivalent. 4+ years of experience working in a Trust & Safety dom

PythonSQLRestMachine Learning
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s mission is to ensure the responsible and widespread adoption of artificial intelligence. In support of that mission, the Marketing team helps deeply understand customer audiences and market dynamics, influence the development of the right products, build sustainable and customer-aligned monetization models, and drive awareness, adoption, and usage across OpenAI’s products and platform. We take a data-driven approach to understand markets, develop monetization strategies, and uncover customer needs that shape product strategy and messaging. We partner closely with Sales, Partnerships, Product, Engineering, Research, Comms, and Design to deliver a cohesive end-to-end customer experience and lead go-to-market efforts for new product launches across channels. About the Role As a Product Marketing Manager, Research & Safety , you will shape how the world understands OpenAI’s frontier research and our approach to developing AI responsibly. You will establish the strategic narrative for some of the company’s most important research themes—including frontier capabilities, safety, preparedness, reasoning, and compute—and translate complex technical work into clear, credible stories for researchers, policymakers, and the broader public, working with cross-functional teams to translate that messaging and reach developers and enterprise. Working closely with Research, Safety Systems, Policy, Communications, and Product teams, you’ll lead the go-to-market strategy and messaging for major research and safety initiatives. You’ll develop narratives that build trust, translating technical concepts into tangible artifacts and messaging, drive industry understanding of emerging evaluation frameworks, and help communicate OpenAI’s unique perspective on responsible frontier AI development. You’ll also identify creative and non-traditional ways to bring these stories to the audiences that matter most. In this role, you will: Establish the strategic narrative f

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $280.5K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Every day, Roblox users play over 7M experiences, make over 270M avatar updates, send 6+ billion chat messages and talk for 1+ million hours using voice. Safety is Roblox’s top priority. As part of the Safety Group, the Content and Communications Safety team builds AI features and tools to automate review and moderation of all of these activities on the platform. Areas that the Content Safety Team works on include: Experience reviews The components that make up those experiences (textures, 3D meshes, models, scripts) Avatars, Avatar items Audio, Video Text chat and voice conversations and other content types As a Senior Product Manager on the team, you will work closely with leadership, product, engineering, data science, and operations teams across Roblox. In addition, you will drive critical company-level KPIs that affect how Roblox keeps the platform safe and civil. As we bring new immersive features and content types to Roblox, you will be responsible for leading the product in one of the most challenging and vital roles at Roblox. You will Lead safety features focused on automation of content reviews by leveraging AI Stay one step ahead of malicious actors and their adversarial tactics

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