Jobs in United States

Senior Applied Scientist in United States

2,111 active opportunities · Updated October 2026

Explore current senior applied scientist jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 New York, New York, United States· Full-time
✓ High-confidence listingExact matchCompany trend -89.3%

From $220K/yr

Quick readExact title match for your search

The Applied AI team designs and builds algorithmically driven features in the Datadog app. We work across a range of applications, primarily focusing on analysis on streaming data such as anomaly detection, error outliers and faulty deployment analysis. As an Applied Scientist you will work on building models and algorithms for machine learning powered features within the Datadog platform. You will work closely with our engineering and product partners to explore, build, scale and deliver these features that we incubate within the Applied AI team. At Datadog, we place value in our office culture - the relationships that it builds, the creativity it brings to the table, and the collaboration of being together. We operate as a hybrid workplace to ensure our employees can create a work-life harmony that best fits them. What You’ll Do: Design solutions for our different use cases. You will research and benchmark relevant algorithms to find the best fit for our use-cases Leverage machine learning algorithms and statistical techniques to build new scalable product features Develop, deploy and monitor new and existing features to production Participate in our journal club by reading and presenting the latest academic research papers to the team Explore, analyze and tell the story behind high volumes of data flowing through Datadog systems Maintain and monitor the models, services and infrastructure owned by your team Participate in your team’s on-call rotation Who You Are: You have a BS/MS/PhD in a Computer Science, Engineering, Machine Learning or related scientific field or equivalent experience You have experience working with high-scale systems and datasets including building models, applying machine learning to real business problems, and writing production data pipelines You can explain complex ideas and algorithms to non-technical audiences You care about code simplicity and performa

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📍 New York, NY, United States· Full-time
✓ High-confidence listingCompany trend -99.2%

From $10K/yr

Quick readStrong listing-quality and freshness signals

About Ramp Ramp is building the smart infrastructure for finance teams, embedded in the transaction flow of every dollar a business spends. We automate how over $200B in annualized spend flows in and out of 70,000+ companies: authorizing payments, flagging risk, categorizing spend, and closing books. The problems are high-stakes, data-dense, and unforgiving. We hire people with high agency and high urgency. We look for slope over intercept. We care less about where you trained and more about what you’ve built. At Ramp, everyone is a builder who owns problems end to end and makes consequential decisions that shape the outcome. The median Ramp customer saves 5% and grows revenue 16% in their first year – far in excess of businesses operating without Ramp. We believe every ambitious company deserves the same. If you want to build systems that directly shape how companies move and manage billions, Ramp is the place to do it. About the Role We’re looking for a Senior Applied Scientist to help drive the future of credit applied science at Ramp. In this role, you will design, build, and optimize the models that power our credit risk systems, helping us make faster, smarter, and more scalable risk decisions for our customers. You’ll work at the intersection of machine learning, statistics, economics, and product strategy. This role requires strong technical depth as well as close collaboration with business, product, data, and engineering partners. You will help identify high-impact opportunities, translate ambiguous business problems into rigorous modeling work, and ship models that operate reliably in production. Applied scientists at Ramp focus on solving quantitative problems across credit, fraud, growth, and our core product by applying the right mix of machine learning, causal inference, structural modeling, and optimization. What You'll Do Design, build, and optimize machine learning models that support credit risk decisioning and portfolio management at Ramp Own the

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📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -90.5%

From $240K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview The Advertiser Optimization team is the decision-making engine of Instacart's $1B+ ads business. We own the systems responsible for Bidding, Pacing, Budgeting, and Targeting: converting stated advertiser goals into real-time auction actions. Our mission is to maximize realized Advertiser Value by deciding when to participate, how much to bid, and how fast to spend, all while balancing User Experience and Platform Revenue. We are hiring a Senior Applied Scientist II to lead the algorithmic direction of these systems. This is a role for someone who thinks in terms of control theory, constrained optimization, and auction economics, and who can translate those frameworks into production code that makes millions of decisions per day. You will formulate problems from first principles, shape the technical roadmap, and own systems end-to-end from mathematic

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📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -93.7%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. About the Team The Finance Data Science team owns the forecasting systems that power Snowflake’s financial planning, operating cadence, and long-term strategy. Our work informs executive decision-making, corporate planning, investor reporting, and cross-functional decisions across Finance, Sales, and Product. We build and operate production forecasting systems for Snowflake’s core money-in metrics, with a particular focus on revenue and bookings in a consumption-based business. Our forecasts are highly visible, widely used, and foundational to how the company plans and operates. This is a high-trust team operating at the intersection of statistical modeling, production systems, and financial decision-making. The Role We are hiring a Senior Applied Scientist to own and advance mission-critical forecasting systems used across the company. This role is not just about building models. It is about developing reliable, explainable, production-grade forecasting systems that leaders can trust to make decisions. You will work on high-impact, open-ended problems involving revenue forecasting, customer consumption behavior, workload ramps, renewals, and other leading indicators that feed Snowflake’s broader financial planning processes. You will partner closely with Finance, Sales, Pr

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why This Role Is Different This is not a typical “Applied Scientist” or “ML Engineer” role. As a Member of Technical Staff, Applied ML, you will: Work directly with enterprise customers on problems that push LLMs to their limits. You’ll rapidly understand customer domains, design custom LLM solutions, and deliver production-ready models that solve high-value, real-world problems. Train and customize frontier models — not just use APIs. You’ll leverage Cohere’s full stack: CPT, post-training, retrieval + agent integrations, model evaluations, and SOTA modeling techniques. Influence the capabilities of Cohere’s foundation models. Techniques, datasets, evaluations, and insights you develop for customers will directly shape the next generation of Cohere’s frontier models. Operate with an early-startup level of ownership inside a frontier-model company. This role combines the breadth of an early-stage CTO with the infrastructure and scale of a deep-learning lab. Wear multiple hats, set a high technical bar, and define what Applied ML at Cohere becomes. Few roles in the industry combine application, research, customer-facing engineeri

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📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -84.7%

About the Team OpenAI’s People team hires, engages, and retains world-class talent to safely build and deploy AGI that benefits all of humanity. The People Analytics team helps leaders make rigorous, evidence-based talent decisions and ensures that the systems supporting those decisions are valid, reliable, fair, and accountable. About the Role As a People Data Scientist focused on AI fairness and bias testing, you will help establish how OpenAI evaluates AI-assisted People systems and high-impact talent processes. You will design and conduct rigorous assessments to identify, measure, and mitigate potential bias across the lifecycle of models, agents, decision-support tools, and automated workflows. Your work will span the entire employee life-cycle, such as hiring, performance, promotion, employee development, workforce planning, etc. You will evaluate both technical systems and the broader human-AI decision processes in which they operate, examining not only model performance but also data quality, measurement validity, differential outcomes, human oversight, and unintended consequences. We’re looking for an experienced data scientist or applied researcher who can translate complex fairness questions into defensible evaluation strategies, scalable testing infrastructure, and clear recommendations for technical teams and senior leaders. This role is preferred to be based in San Francisco, CA. In this role, you will: Define and lead fairness and bias-testing strategies for AI-assisted People processes, models, agents, and decision-support systems from development through deployment and ongoing monitoring. Design rigorous algorithmic audits and validation studies, including adverse-impact analysis, subgroup and intersectional evaluation, error-rate analysis, calibration, measurement invariance, reliability, criterion-related validity, and sensitivity testing. Identify the appropriate fairness criteria for each use case, evaluate tradeoffs among competing definitions

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📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -74.6%
Quick readStrong listing-quality and freshness signals

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. We are the Fraud Data team within Plaid's Fraud organization. We leverage relationships and activity across Plaid’s network to develop machine learning models that help customers detect and prevent fraud while minimizing friction for legitimate users. Our team owns the full model lifecycle, from data processing and experimentation to feature pipelines, model serving, and monitoring. In this research role, you’ll partner closely with Machine Learning Engineers and Data Scientists to uncover new signals, explore and evaluate innovative modeling approaches, and translate promising research into production-ready solutions that strengthen fraud detection across Plaid’s network. As a Senior Research Scientist, you will lead applied research to develop next-generation fraud detection models across relational graphs, sequential events, images, and video data. You’ll design rigorous experiments and evaluation methodologies that reflect real-world fraud dynamics, while exploring state-of-the-art approaches such as Graph Neural Networks and Transformer-based foundation models. In close partnership with Machine Learning Engineers, you’ll translate promising research into production-ready solu

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📍 United States· Full-time
✓ Quality checkedCompany trend -92.7%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Our Data and Analytics team is currently looking for a Senior Data Scientist to join us! You’ll be responsible for laying the foundation for a best-in-class business analytics function. You’ll partner closely with our business stakeholders to ensure that our analytics stack and processes meet the business needs today with an eye towards the future. What you’ll do as a Senior Data Scientist at Vanta: Build and maintain trusted product data assets using dbt, Snowflake, and modern analytics infrastructure Leverage AI-powered analytics tools and data agents (e.g., Snowflake Cortex) to accelerate insight generation, automate repeatable analysis, and scale decision-making Define and evolve measurement frameworks for product health, customer lifecycle, and AI-powered product experiences Partner closely with Product, Engineering, Design, and Customer Success to influence product strategy through data Help define Vanta’s analytics strategy and AI measurement practices as our product and data platform evolve Lead executive analytics reviews, translating complex analyses into clear recommendations that drive company decisions How to be successful in this role: 4+ years of experience working with data as a Data Scientist, Product Analyst, or Analytics Engineer in an applied business setting Strong foundation in SQL, Python (or R), statistics, and machine learning Experience designing and evaluating experiments, predictive models, and other statistical analyses to inform product decisions Experience building scalable data assets, metrics, and analytical frameworks on modern cloud data platforms (e.g., Snowflake, dbt) Deep experience with da

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📍 Chicago, Illinois, United States· Full-time
✓ Quality checkedCompany trend -93.7%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Our Solution Engineering organization is seeking an AI Specialist who can provide hands-on expertise and support while working with technical decision makers and data scientists to design and architect AI solutions built on the Snowflake AI Data Cloud. This is a strategic role that works closely with cross-functional teams, including product, engineering, and the broader field organization to ensure successful execution and customer adoption of Snowflake’s AI & ML solutions. IN THIS ROLE YOU WILL GET TO: Be the technical expert in the room that positions Snowflake’s AI and ML features and value to technical stakeholders at Snowflake’s customers across the Americas. Partner with Snowflake account team teams and customer champions to scope and drive POCs to success and technical wins that prove the value of Snowflake’s capabilities, including executive readouts and business value cases. Collaborate with Snowflake’s product and engineering teams to influence Snowflake’s AI and ML roadmaps based on customer feedback. Publish content that helps the team and company scale beyond your individual efforts, like blog posts, presentations at conferences, or technical collateral like notebooks and demos. Influence, tailor and maintain Sales Engineering AI and ML selling assets, inc

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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -93.7%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Our Solution Engineering organization is seeking an AI Specialist who can provide hands-on expertise and support while working with technical decision makers and data scientists to design and architect AI solutions built on the Snowflake AI Data Cloud. This is a strategic role that works closely with cross-functional teams, including product, engineering, and the broader field organization to ensure successful execution and customer adoption of Snowflake’s AI & ML solutions. IN THIS ROLE YOU WILL GET TO: Be the technical expert in the room that positions Snowflake’s AI and ML features and value to technical stakeholders at Snowflake’s customers across the Americas. Partner with Snowflake account team teams and customer champions to scope and drive POCs to success and technical wins that prove the value of Snowflake’s capabilities, including executive readouts and business value cases. Collaborate with Snowflake’s product and engineering teams to influence Snowflake’s AI and ML roadmaps based on customer feedback. Publish content that helps the team and company scale beyond your individual efforts, like blog posts, presentations at conferences, or technical collateral like notebooks and demos. Influence, tailor and maintain Sales Engineering AI and ML selling assets, inc

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.7%

About the Team The Youth Well-Being product team is part of the Integrity pillar at OpenAI, responsible for ensuring that our state-of-the-art AI technologies are deployed in safe, age-appropriate, and beneficial ways—especially for youth and families. We work across OpenAI’s entire product surface area, from ChatGPT to future-facing tools, to architect safety and trust into the foundation of our systems. Our mission: empower families while meeting the highest standards of regulatory compliance and ethical responsibility. This work is core to OpenAI’s mission to ensure AGI benefits all of humanity. Safety, especially for the most vulnerable users, is more important to us than unfettered growth. About the Role We’re looking for a Senior Software Engineer to help architect and build the foundational systems that power family- and youth-facing experiences at scale. You’ll help define how teens and guardians engage with OpenAI products—ensuring those experiences are safe, compliant, and empowering. You’ll operate across a broad technical surface: building identity primitives, age assurance pipelines, and guardian tools that support both proactive and reactive interventions. You’ll collaborate closely with a cross-functional team of engineers, data scientists, designers, user researchers, and policy experts. This is a high-impact, 0→1 opportunity to set the standard for how families interact with generative AI. In this role, you will: Architect and implement teen and guardian experiences across OpenAI products, including ChatGPT. Build global age assurance systems that are privacy-preserving and tailored to regional compliance needs. Design and evolve our identity infrastructure to support scalable, secure, and resilient user journeys at consumer internet scale. Help define safety and well-being metrics, and continuously improve user trust through technical interventions. You might thrive in this role if you: Have built products or infrastructure for users under 18, or h

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📍 California, Foster City, United States
✓ High-confidence listingCompany trend -1.6%

$243.1K – $314.6K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Director, Applied AI Solutions, leads the applied AI function within the AI Research Center (ARC), part of Gilead’s Clinical Data Science (CDS) organization in Drug Development. As CDS’s center of excellence for applied AI, this leader is accountable for the technical and product path from a prioritized AI use case defined by CDS functional organizations to a trusted, reusable capability in production — spanning discovery, experimentation, technical validation, first production release, adoption support, and measured value. The ownership model is deliberate. Business ownership of priorities, requirements, funding, process change, and workflow outcomes remains with the CDS and Develo

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📍 Santa Clara, United States
✓ Quality checkedCompany trend -13.7%

Build the infrastructure that keeps every NVIDIA chip aligned from first spec to final shipment. NVIDIA's Silicon Co-Design Group sits at the convergence of architecture, silicon, systems, and manufacturing. The System–Manufacturing Architecture (SMAC) team coordinates between system specifications and manufacturing test specifications from pre-silicon POR through production release across GPU, SoC, and CPU programs. When that alignment drifts, silicon faces the consequences: escapes, yield loss, and performance loss. We're hiring a Senior Manufacturing & System Co-Design Workflow Engineer to lead the methodology and infrastructure that maintains holistic, systematic alignment, at scale across the full portfolio. The strongest candidates in this role design the workflow before being asked to fix a program, and build the checks and automation that confirm alignment holds long after they've moved on to the next problem. What you’ll be doing: SMAC Workflow Methodology: Define manufacturing spec types, including schema and semantics, derived from system PORs and features. Own the methodology that governs how specification work gets structured, versioned, and validated across the program lifecycle. Production Python Pipelines & Automated Checks: Develop production-grade Python pipelines and automated checks that catch specification drift between system POR and manufacturing test programs ,ATE, SLT, BLT, L10+, before silicon exposes the discrepancy. The goal is that misalignments surface in the workflow, not on the tester. E2E Program Integration & TPM Attestation: Wire SMAC work into the end-to-end program spine, milestones, gates, and artifacts, and define explicit TPM-driven attestation when checks lag. Alignment can't be assumed; it must be proven at every stage. Agent-Ready Tooling & CI Infrastructure: Integrate tooling into an agent-ready

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -93.7%

$166.9K – $225.9K/yr

Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: Drata is seeking a Senior Applied AI Engineer to drive the quality and effectiveness of our AI systems through rigorous experimentation, evaluation, and applied research. This is a research-focused role emphasizing experimentation and rigor over production engineering. You'll own the science behind how Drata's AI products retrieve, reason, and respond — and you'll work closely with

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