Upstream Process Development Lead in United States

ROLE SUMMARY This laboratory-based leadership role will lead upstream process development for both mammalian cell culture and microbial fermentation platforms within Vaccines Early Bioprocess Development (EBPD). The incumbent will provide scientific and people leadership for the design, planning, execution, and interpretation of experiments supporting recombinant protein and vaccine antigen production. The role requires strong expertise in upstream process development, including host and cell-line evaluation, media and feed optimization, bioreactor process development, and integration of product yield and quality considerations. The successful candidate is expected to bring deep expertise in at least one platform, mammalian cell culture or microbial fermentation, together with demonstrated knowledge of and ability to lead programs across the other platform. Responsibilities include application of high-throughput and scale-down models, Design of Experiments (DOE), process characterization and modeling, scale-up, technology transfer, and development of processes suitable for good manufacturing practice (GMP) manufacture. Experience with automated and conventional bioreactor systems, such as ambr, stirred-tank bioreactors, and rocking-motion bioreactors, is highly valued. The role requires rigorous documentation, clear communication of data and recommendations, effective cross-functional collaboration, and a proven record of scientific and team leadership. ROLE RESPONSIBILITIES · Provide scientific and people leadership for the upstream process development workstream spanning mammalian cell culture and microbial fermentation within the Vaccines EBPD Process Development group. · Lead the design, prioritization, execution, documentation, and communication of complex studies to improve cell growth, recombinant protein expression, prod

We anticipate the application window for this opening will close on - 5 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life In this role, you will help bring innovative medical technologies from concept into commercialization by leading manufacturing engineering efforts for metal additive manufacturing processes within New Product Introduction. The Principal Manufacturing Engineer will support both upstream and later-stage NPI activities, partnering closely with cross-functional teams to develop robust, scalable, and compliant manufacturing solutions that enable successful product launches and long-term operational performance. This position requires deep technical expertise in metal additive manufacturing, strong process development capabilities, and experience operating within a regulated environment. The ideal candidate will be equally comfortable supporting early feasibility and design collaboration as well as process validation, design transfer, and production readiness activities. At Medtronic, we bring bold ideas forward with speed and decisiveness to put patients first in everything we do. In-person exchanges are invaluable to our work. We’re working a minimum of 5 days a week onsite as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary. Responsi

What You Will Achieve A Senior Scientist (R 4 ) position is available in the Upstream Process Development group within the Bioprocess R&D organization. The successful applicant will join a team of scientists and engineers focused on developing and optimizing manufacturing processes for recombinant proteins and other modalities for early- and late-phase human clinical trials. In this role, the candidate will be responsible for designing and executing laboratory experiments in bench-top bioreactors and associated scale-down equipment with the goal of developing robust, scalable, and high productivity processes. The work will also involve collaborating with pilot, clinical, and commercial production facilities to ensure accurate technology transfer, successful large-scale production and associated regulatory filing activities. The candidate may also be involved in cutting edge technology development projects that seek to improve production processes and control strategies leveraging various process analytical technologies. How You Will Achieve It Design and execute

Job Details: Job Description: The Thin Films Senior Process Engineer will support PVD, CVD, and ALD technologies for dielectric and metal thin-film deposition in a high-volume manufacturing environment. Key Responsibilities Apply advanced expertise in thin-film deposition processes to drive continuous improvement in process performance, sustainment, and technology development. Collaborate with upstream and downstream partners to deliver manufacturing improvements through strong cross-functional engagement and stakeholder management. Own manufacturing processes and/or equipment, ensuring achievement of key performance indicators (KPIs) including safety, quality, cost, productivity, defect reduction, and yield improvement. Develop and execute strategic plans for complex projects, coordinating timelines and dependencies across multiple teams and initiatives. Support manufacturing capacity expansion and technology transfer activities to enable successful ramp-to-volume production. Partner with equipment vendors and cross-functional stakeholders to troubleshoot technical challenges, improve tool performance, and enhance operational efficiency. Lead process development initiatives that support current and next-generation high-volume manufacturing technologies. Design and optimize excursion prevention and detection systems to strengthen process control and minimize manufacturing risk. Lead equipment installation, conversion, qualification, and readiness activities during factory ramps, ensuring all tools are deployed safely, on schedule, and in compliance with quality and manufacturing standards. Drive root cause analysis and implement corrective actions to resolve process and equipment-related issues while improving overall manufacturing stability and performance. <p st

Work Flexibility: Onsite What You Will Do: This role is on the Electrical Engineering team at Stryker Medical division's Acute Care business unit. We primarily work with patient handling and patient care equipment within the hospital space such as stretchers, hospital beds, and support surfaces. This role falls under the team addressing the high-acuity market, with a focus on products that often come into direct contact with patients. It includes gaining a deep understanding of customer needs through research and partnership with upstream marketing and through direct interactions with customers. Working with a diverse team, you will design, develop, modify, evaluate, and verify electrical components and sub-systems for medical devices. The role includes the full development process from research to product launch. Design and develop electrical circuits and subsystems for medical devices. Coordinate engineering changes and complete documentation in accordance with quality management system requirements. Review and modify C/C&#43;&#43; code to support product functionality and performance Apply electrical system and circuit test methods to evaluate product designs. Build and support prototypes and conduct bench testing activities. Collaborate with manufacturing, sourcing, and cross-functional teams to support ongoing production activities. Analyze and test designs for electromagnetic compatibility, reliability, safety, manufacturability, and testability. Support

Become a part of our caring community Services represent one of the organization’s most consequential sources of capability, capacity, transformation and external spend. The Associate Vice President, Services Procurement will lead the enterprise strategy for contingent workforce, outsourcing and offshoring, consulting and clinical services, converting third-party services into measurable business outcomes, workforce agility, operating leverage and sustainable value. The AVP will serve as the senior Procurement partner to leaders across the Insurance segment and Corporate Services, helping shape operating-model, workforce and transformation decisions before sourcing begins or a supplier solution is selected. The leader will bring deep expertise in global business services, business process outsourcing, workforce solutions and complex professional services. The mandate is to strengthen business-case quality, establish clear make, buy, build, automate and partner choices, create fit-for-purpose commercial models, manage transitions and hold providers accountable for committed outcomes. Success will be measured by whether business leaders make better services and workforce decisions, transformations deliver their promised value, and suppliers improve performance and innovation. Key Responsibilities Serve as the Strategic Services Partner to Business Leaders Serve as the senior Procurement relationship leader and trusted commercial advisor to Insurance segment and Corporate Services leadership. Develop a deep understanding of business strategy, operating plans, transformation roadmaps, workforce needs and financial commitments, and translate them into integrated services, workforce and supplier strategies. Engage upstream of supplier selection to frame the problem, test demand and assess make, buy, build, automate, offshore, outsource

About the Team OpenAI is building the world’s most advanced AI infrastructure ecosystem. The Site Readiness & Development team owns the upstream diligence and development work required to convert powered-land opportunities into executable infrastructure options. About the Role The Site Selection Lead sets the site-selection strategy for powered-land and greenfield/brownfield opportunities. This role defines, with cross-functional partners, what makes a site attractive, executable, and scalable, then turns that shared rubric into portfolio choices and deployment plans. Key Responsibilities Own the site-selection strategy across priority geographies, including market maps, pipeline segmentation, source refreshes, live-location tracking, and portfolio prioritization. Convene Power, Land, Development, Engineering, Construction, Environmental, Community, Commercial, Legal, and Finance partners to define the shared rubric for a high-quality site. Translate that rubric into clear screening criteria across power readiness, land control, timing, scale, cost, community risk, environmental constraints, AHJ path, budget, schedule, and counterparty credibility. Orchestrate Commercial, Legal, Finance, Power, and Development teams to shape exclusivity, initial terms, site-control strategy, funding assumptions, and the path to deployment before deeper commitment. Build a deployment plan for top candidates that identifies capacity, sequencing, capital implications, critical-path approvals, risks, owners, and stage-gate decisions. Lead conceptual site planning and test-fit screening using boundaries, map layers, buildings, substations, roads, parking, laydown, stormwater, utility corridors, acreage, and estimated load. Maintain a single decision-support view of pipeline stage, site health, power readiness, finance review, maps, project evidence, outstanding source data, owners, deadlines, and escalations. Present executive-ready advance, defer, or stop recommendations with clear

About the Team OpenAI, in close collaboration with our capital partners, is building the world’s most advanced AI infrastructure ecosystem. The Site Readiness & Development team owns the upstream diligence and development work required to convert powered-land opportunities into executable infrastructure options. About the Role The Power Land Developer; Development & Power Projects will support the advancement of powered-land opportunities across the portfolio, reporting to the Development & Power Project Lead. This is an individual contributor lead role and does not have direct reports initially. This role will own day-to-day development execution across approximately 1–3 active sites depending on complexity, including utility applications, interconnection requests, study follow-through, queue milestones, consultant workstreams, schedule and risk management, and readiness handoff for opportunities advancing to deeper diligence, commercial commitment, or execution. The role translates study and utility findings into clear schedule, budget, and risk implications for portfolio decisions. Responsibilities Manage day-to-day advancement of powered-land opportunities from intake through readiness. Own utility application and interconnection follow-through across active powered-land opportunities, including utility inputs, study responses, and queue milestones. Scope and manage external studies and consultant workstreams needed to validate readiness. Track development schedules, dependencies, risk registers, site-readiness milestones, and key budget implications. Translate technical findings into clear schedule, budget, and risk implications and escalate material blockers or trade-offs to the Development & Power Project Lead. Partner with land, environmental, economic development, and community affairs leads to align project advancement. Support expansion planning, infrastructure sequencing, and long-term power-risk mitigation. Define readiness criteria and

We are looking for a Senior System Software Engineer, Software Defined Networking to design, build, and operate highly performant and scalable SDN solutions for NVIDIA's AI Clouds hosting GPU-accelerated workloads — including hyperscale multi-node training, inference, cloud gaming, and cloud functions. This role spans the full lifecycle of our SDN stack — from designing and developing new control and data plane software to ensuring operational excellence in production through reliability engineering, CI/CD, observability, and incident response. What you'll be doing: Design and develop next-generation multi-tenant cloud SDN control and data plane software (OVS, OVN, OpenFlow) Build Infrastructure-as-a-Service virtual network orchestration and services using gRPC and REST to support tenant workload security and performance SLAs for BMaaS, VMaaS, and Kubernetes Drive upstream contributions to OVN-Kubernetes and related open-source projects Develop software for network observability — monitoring, telemetry, intelligent metering, and performance analysis Operate and support OVS-OVN based SDN solutions in large-scale NVIDIA AI Cloud environments Own end-to-end observability for the SDN stack — build and maintain monitoring, alerting, distributed tracing, and dashboarding to ensure real-time insight into network health, performance, and tenant SLAs Design, enhance, and maintain CI/CD pipelines (GitLab) across Linux host networking, OVS, OVN, and Kubernetes CNIs Implement GitOps approaches or related experience for secure, seamless integration with cloud infrastructure Drive reliability through incident management, resource monitoring, and performance tuning<

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team The GTM Product Marketing team sits within Stripe's Product Marketing org. We make sure Stripe sellers walk into every conversation prepared, confident, and armed with the right story. As Stripe's center of excellence for general product enablement, we set the standard for how sellers learn and pitch our products, drive consistency across product suites, and act as Marketing's Voice of the Field — surfacing seller insights to sharpen upstream messaging and positioning. We translate product value into seller-ready narratives, resources, and enablement — and we measure our impact on seller confidence and how effectively our teams pitch, qualify, and close. Stripe's Commerce Experiences products (Optimized Checkout Suite, Link, Terminal, Agentic Commerce) help businesses convert more customers across every channel — from online checkout, to digital wallets, to in-person commerce, to the emerging world of AI-driven shopping. We're looking for an exceptional GTM product marketer to bring Stripe's story to market. In this role, you'll be the connective tissue between product, marketing, and the field. You'll translate complex commerce and checkout capabilities into compelling narratives and seller resources that resonate with our users and drive adoption. You'll equip customer-facing teams to confidently pitch all our solutions, answer technical questions, and speak to the roadmap. You'll also elevate seller and field insights to refine produc

The Silicon Co-Design Group (SCG) sits at the crossroads of architecture, design, marketing, operations, and productization. Our work spans early architecture through final product delivery across Datacenter, Gaming, Robotics, Automotive, and Embedded markets. We work closely across functions to deliver chips that change what is possible. System Integration sits at the intersection of all of them. It is the layer where every architecture, design, software, and manufacturing decision meets reality. When something breaks late in a program, it usually breaks here first. We are hiring a Senior Manager to lead this team in the US and partner closely with teams globally. Your work will sit on the critical path of every NVIDIA silicon program, and the bar you set for system integration is the bar we ship to! The two hardest, highest-leverage problems in this seat: Find critical silicon issues earlier — often before software is production-ready. Left-shifting post-silicon coverage is the highest-value thing System Integration can do. Standing up wide-area testing as a repeatable capability is a core part of the role. Keep programs on milestone when upstream dependencies slip. Validation plans collide with reality every program! The team needs new strategies, not just contingency plans, to keep moving when software, firmware, or methodology slip. You will design and run those strategies. What you’ll be doing: Plan and execute post-silicon feature integration, PVT validation, and wide-area testing across NVIDIA’s GPU, SoC, and CPU programs. Build wide-area and in-system test as a repeatable capability that shifts post-silicon coverage left, so issues surface before we are production-ready. Lead resolution of the most complex system-level issues, RMAs, and HW/SW interaction problems with creative workarounds and focused lab experimentation. Deve

About Us: AI needs a new infrastructure layer. We're building it at Modal. Every era of computing brought new workloads that previous infrastructure couldn't support: mainframes, databases, and the cloud. Each time, the company that rebuilt the layer underneath defined the decade. AI is no different, except it touches everything instead of one slice, and the window to build the layer underneath it is open right now. Our customers include category-defining companies like Lovable , Ramp , Cognition, DoorDash, and Suno. They rely on Modal for instant GPU access, sub-second container starts, and native storage, so it's simple to serve low-latency inference, fine-tune models, and access production-ready sandboxes at scale. We recently raised a $355M Series C at a $4.65B valuation, led by General Catalyst and Redpoint Ventures. We've crossed $300M+ ARR and grown fivefold since September. Our team includes creators of popular open-source projects (e.g., Seaborn , Luig i ), academic researchers, international olympiad medalists, and experienced engineering and product leaders with decades of experience. The Role: We are looking for a strong technical lead to guide the engineers designing, building, and maintaining the novel, high-performance systems that make up our serverless platform. You'll lead the team responsible for the distributed object storage system that underpins every container image, volume, and checkpoint on Modal: hundreds of petabytes of data, replicated across multiple cloud object stores and a CDN, cached on local NVMe across a large fleet of workers in many datacenters, and shared peer-to-peer within each datacenter. You'll set technical direction for the primitives that other teams (filesystems, training, sandboxes) build on, balancing durability, latency, throughput, and cost. You'll own the roadmap from today's hardest problems (garbage collection at petabyte scale, active-active replication, rate limiting that protects the upstream without wasting ut

Senior Designer Description - ABOUT THE ROLE We’re looking for a Senior Designer who leads by doing. This is an equal-parts strategic and hands-on role — someone who sets the creative bar for our in-house agency, earns credibility through exceptional work, and isn’t afraid to roll up their sleeves when it matters. You champion design excellence, can defend your decisions with clarity and confidence, and help grow the people around you. This role sits within a balanced creative environment: you’ll have real influence over the work, while partnering closely with internal clients across marketing, sales, and product who hold final approval. Success here means earning trust through quality and communication, not just creative instinct. Day-to-day you’ll operate across mid-to-lower funnel channels — social, ecommerce, retail, sales enablement, and short-form video. You think like a creative director but know that craft lives in execution. Production is where the rubber meets the road, and you’re proud to be there. WHAT YOU’LL DO Produce exemplary design work across social, etail, retail, sales decks, and short-form video that raises the quality bar for the whole team Partner with internal clients across marketing, sales, and product — translating briefs into design that performs and building lasting working relationships Concept and execute with both visuals and words — thinking across design and messaging together, not in isolation Defend design decisions with strategic rationale, balancing business goals with creative integrity Contribute upstream — shaping briefs, influencing strategy, and catching creative problems before execution begins Maintain and evolve brand standards, ensuring visual consistency across all channels and touchpoints Build scalable systems — templates, as

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team Brand Studio sits at the center of everything Stripe shows the world — from visual identity and brand systems to campaigns, events, digital experiences, and global marketing. The studio functions as a creative multiplier: setting the standards, building the systems, and producing the work that helps Stripe show up with intention and quality across every touchpoint. World-class creative output requires world-class operational infrastructure. Brand Operations is the function that makes Brand Studio's work possible at scale — not by managing the execution, but by architecting the conditions that enable it. That means shaping what enters the studio, ensuring clarity before a brief is written, and building the systems that allow creative directors and producers to focus on what they're here to do: create exceptional work. What you’ll do Most operations leaders are brought in to fix problems. We're looking for someone who prevents them — and designs the system in which prevention becomes the norm. The Head of Brand Operations exists upstream from creative execution. This role's job is to ensure the work entering Brand Studio is strategically aligned, clarified, prioritized, resourced, and fully prepared for delivery before it ever reaches a creative director or producer. It also means ensuring the company understands how to work with Brand Studio — what it takes to be a ready partner, and where a given initiative stands on the roadmap. When th

We are developing advanced multi-rack, multi-tenant AI/ML datacenters with NVIDIA GB200, and upcoming GB300 GPUs. NVIDIA seeks a Senior Software Engineer for our CSP (Cloud Service Provider) Engagements team to focus on the cloud-native stack for datacenter products like GB200. In this role, You will define customer workflows, prototype stack enhancements, and debug the toughest Kubernetes &#43; Slurm issues in multi-rack, multi-tenant AI datacenters. You'll tackle complex scheduling challenges across racks, tenants, and clouds as part of the CSP engagements team. What you’ll be doing: Perform deep-dive debugging of multi-rack, multi-tenant clusters: scheduler behavior, container runtime issues, device-plugin crashes, RDMA/IB fabric anomalies, etc. Gather customer requirements and prototype feature extensions for Kubernetes operators, Slurm plugins, and custom micro-services that expose new GPU capabilities. Drive joint architecture reviews and “whiteboard” sessions with CSP and internal platform teams; convert findings into RFCs and upstream pull requests. Create reproducible testbeds (Helm/Ansible/Terraform) that mirror customer environments; automate validation and benchmark suites. Deliver technical collateral-design docs, how-to guides, demo scripts-and present at customer on-sites, KubeCon, and SlurmUG. Collaborate with AE, FAE, and Solution Architect teams to deliver integrated customer solutions and technical documentation. What we need to see: Strong source-level expertise in Kubernetes internals (scheduler, CRI/CNI/CSI, operators) and Slurm (federation, power-save, plugins). Hands-on experience integrating next-gen GPUs (Blackwell/GB200/GB300) or comparable accelerators into containerized clusters. Proven track record debugging large-scale, cloud-native stacks across ne