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Lead Enterprise Systems Engineer in San Francisco

165 active opportunities · Updated October 2026

Explore current lead enterprise systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $182K/yr

Quick readStrong listing-quality and freshness signals

At Scale, we develop reliable AI systems for the world’s most important decisions. Scale’s product marketing team is responsible for developing and executing strategies that drive awareness and engagement for Scale’s offerings amongst our core audiences. We take a data-driven approach to understand our customers’ needs and challenges, ensuring that their voices are reflected in product development and messaging. We partner closely with product, engineering, research, sales, comms, and the broader marketing team to create a cohesive customer experience across all our channels. We aim to provide valuable insights and resources that help our customers execute on their AI transformation journey. This role will focus on developing and optimizing vertical-specific messaging and content for Scale’s applications business to ensure our messaging resonates with core buyers across verticals. The ideal candidate combines strategic thinking with hands-on execution. You will: Develop clear, compelling messaging for enterprise offerings tailored to key personas within target verticals Create marketing assets, including slide decks, videos, blog posts, and one-pagers, that effectively communicate our value propositions to vertical leaders and support our sales team’s pursuits Lead positioning and sales enablement efforts to drive awareness and engagement for Scale’s offerings. Drive cross-functional marketing programs around target verticals, in conjunction with product, engineering, sales, and growth marketing to create a cohesive customer experience and contribute to pipeline targets Collaborate with field marketing and events teams to develop vertical-specific event strategies, content, and experiences that drive engagement within customer and target accounts Drive customer marketing efforts, creating both strategy and tactics to maximize the value Scale and customers get from our shared success, including case studies, testimonials, visual assets and event particip

AWSRestAIGo
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $252K/yr

Quick readStrong listing-quality and freshness signals

About Scale AI Scale AI is the data foundation for AI, helping organizations build and deploy reliable production AI applications. We partner with leading enterprises and government organizations to accelerate their AI initiatives through our data annotation platform, generative AI solutions, and enterprise AI capabilities. Role Overview As a Forward Deployed AI Engineering Manager on our Enterprise team, you'll be the technical bridge between Scale AI's cutting-edge AI capabilities and our most strategic customers. You'll work with enterprise clients to understand their unique challenges, lead a team that architects specific AI solutions, and ensure successful deployment and adoption of AI systems in production environments. This is a Management role that combines deep engineering and AI expertise, leading a team, and working on customer-facing problems. You'll work directly with customer engineering teams to integrate AI into their critical workflows. Key Responsibilities Customer Integration & Deployment Partner directly with enterprise customers to understand their technical infrastructure, data pipelines, and business requirements Design and implement custom integrations between Scale AI's platform and customer data environments (cloud platforms, data warehouses, internal APIs) Build robust data connectors and ETL pipelines to ingest, process, and prepare customer data for AI workflows Deploy and configure AI models and agents within customer security and compliance boundaries AI Agent Development Develop production-grade AI agents tailored to customer use cases across domains like customer support, data analysis, content generation, and workflow automation Architect multi-agent systems that orchestrate between different models, tools, and data sources Implement evaluation frameworks to measure agent performance and iterate toward business objectives Design human-in-the-loop workflows and feedback mechanisms for continuous agent improvement Prompt Engineeri

PythonAWSAzureGCP
G
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$250K – $300K/yr

Quick readStrong listing-quality and freshness signals

About Glean: Glean is the Work AI platform that helps everyone work smarter with AI. What began as the industry’s most advanced enterprise search has evolved into a full-scale Work AI ecosystem, powering intelligent Search, an AI Assistant, and scalable AI agents on one secure, open platform. With over 100 enterprise SaaS connectors, flexible LLM choice, and robust APIs, Glean gives organizations the infrastructure to govern, scale, and customize AI across their entire business - without vendor lock-in or costly implementation cycles. At its core, Glean is redefining how enterprises find, use, and act on knowledge. Its Enterprise Graph and Personal Knowledge Graph map the relationships between people, content, and activity, delivering deeply personalized, context-aware responses for every employee. This foundation powers Glean’s agentic capabilities - AI agents that automate real work across teams by accessing the industry’s broadest range of data: enterprise and world, structured and unstructured, historical and real-time. The result: measurable business impact through faster onboarding, hours of productivity gained each week, and smarter, safer decisions at every level. Recognized by Fast Company as one of the World’s Most Innovative Companies (Top 10, 2025), by CNBC’s Disruptor 50, Bloomberg’s AI Startups to Watch (2026), Forbes AI 50, and Gartner’s Tech Innovators in Agentic AI, Glean continues to accelerate its global impact. With customers across 50+ industries and 1,000+ employees in more than 25 countries, we’re helping the world’s largest organizations make every employee AI-fluent, and turning the superintelligent enterprise from concept into reality. If you’re excited to shape how the world works, you’ll help build systems used daily across Microsoft Teams, Zoom, ServiceNow, Zendesk, GitHub, and many more - deeply embedded where people get things done. You’ll ship agentic capabilities on an open, extensible stack, with the craf

JavaScriptPythonJavaAWS
L
📍 San Francisco, Canada· Full-time
✓ High-confidence listingCompany trend -74%
Quick readStrong listing-quality and freshness signals

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. The Lyft Business organization builds the platform that lets organizations move the people they depend on employees, clients, and customers. From the foundational mechanics of a company funding and provisioning a ride to the tailored workflows that get an employee to a client meeting or home after a late shift, we sweat the small stuff to make Lyft the transportation solution businesses build their programs on. As a Staff Software Engineer on the Lyft Business Team, you will act as a critical technical leader, taking holistic ownership of complex systems that span the rider experience, the administrator experience, and the enterprise integrations behind them — defining strategic roadmaps, driving cross-functional alignment, and driving engineering excellence to improve how organizations move their people. Responsibilities: Shape the long-term architecture for systems, taking accountability for both short-term functionality and long-term health Translate high-level business goals into actionable engineering projects. Own the technical roadmap from conception to delivery, managing cross-team dependencies and mitigating risks Champion improvements in system, observability, performance, and tech debt reduction, extending your influence beyond your immediate team Establish best practices for deployment, alerting, and on-call health. Take holistic ownership of the platform's stability, tracking down issues root causes and building preventive safeguards for your immediate scope and beyond. Drive alignment across product, design, and operations. Proactively resolve bottlenecks and make decisive trade-offs to protect system architecture from competing organizational priorities Mentor and level up the engineers around you. Delegate stretch opportunities, lead cross-team reviews, and foster a culture of s

SQLAWSAzureGCP
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $275.2K/yr

Quick readStrong listing-quality and freshness signals

Head of Enterprise GTM Strategy & Operations Reports to VP, Enterprise Sales · SF or NY Reporting to the VP of Enterprise Sales, this role owns both halves of Scale AI’s enterprise revenue engine: the strategy that determines where we play and how we win, and the operating system - people, process, and systems - that makes that strategy executable, measurable, and repeatable. On the strategy side, you set the analytical foundation for enterprise growth: segment and account prioritization, coverage and territory design, pricing and packaging inputs, and the diagnostic work that explains why the funnel behaves the way it does. On the operations side, you own the RevOps stack, forecasting, compensation design, sales enablement, and the operating cadences that convert strategy into predictable quarterly execution. The ideal candidate is equally comfortable building a segmentation model from a blank page and running a Monday morning pipeline review. You will lead an established team, with the Head of Sales Enablement and the RevOps Manager as direct reports. Your first job is to raise the ceiling on what that team delivers: sharper analysis, tighter operating rhythm, and enablement that measurably shortens ramp and lifts win rates. This is a senior, highly visible role partnering with Enterprise Sales leadership, Finance, Marketing, Product, and Solutions Engineering, with regular exposure to the executive team and board materials. STRATEGY Define which segments, industries, and accounts Scale prioritizes, and build the analytical case behind those choices Build and maintain the market sizing, segmentation, and account-tiering models that drive coverage decisions and investment trade-offs Lead hypothesis-driven analyses of the enterprise funnel - win/loss patterns, conversion drivers, deal economics, coverage gaps - and translate findings into specific changes to how we sell Partner with Finance and Product on pricing, packaging, and deal-structure strateg

SQLAWSRestAI
V
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$150K – $210K/yr

Quick readStrong listing-quality and freshness signals

Location: San Francisco, CA (Hybrid) What is Verse? The race to AI has become the race to power. Every breakthrough in artificial intelligence depends on one thing: access to electricity. But across the country, aging grid infrastructure and years-long interconnection queues are slowing the deployment of the data centers that will power the next generation of innovation. Solving this challenge isn't just about energy—it's about unlocking the future of AI. At Verse, we're building the energy intelligence platform for the AI economy. Our software helps the world's largest energy consumers achieve faster, cheaper, and cleaner power by combining real-time control of energy assets with complete visibility into their energy portfolio. Backed by Bessemer Venture Partners, GV, Coatue, and NVIDIA, and built by pioneers in grid-scale batteries, energy markets, and enterprise software, we're redefining how the world's most ambitious organizations access and manage energy. The Role We're seeking an experienced Senior Optimization Engineer to join our Data Science Team. In this role, you will lead the design, development, and deployment of optimization models that power our software platform across applications including electricity markets, renewable energy, and battery energy storage systems. You will be responsible for developing production-grade optimization engines that solve complex operational and planning problems at scale. This role requires deep expertise in mathematical optimization, strong software engineering skills in Python, and experience building optimization models that integrate with production systems. The ideal candidate has significant experience in the energy industry, particularly electricity markets and battery storage optimization. This position emphasizes technical leadership, ownership of complex optimization projects, and collaboration across engineering, product, and commercial teams to deliver high-impact optimization solutions. Key Res

PythonCI/CDAIGo
L
📍 San Francisco, Canada· Full-time
✓ High-confidence listingCompany trend -74%
Quick readStrong listing-quality and freshness signals

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Data Science is at the heart of Lyft’s products and decision-making. Data Scientists at Lyft operate in dynamic environments, moving quickly to build the world’s best transportation solutions.We tackle a wide range of challenges - from shaping long-term business strategy with data, to making critical short-term decisions, to developing algorithms and models that power both internal systems and customer-facing products. Lyft Business builds products that help organizations move the people who matter most - employees, customers, patients, and guests - easily and efficiently. Our offerings include Business Travel, Lyft Pass, and Concierge (for healthcare and non-healthcare rides), enabling companies to manage transportation at scale through APIs, integrations (e.g., Concur, Expensify), and dedicated tools. These platforms power high-impact B2B use cases across corporate travel, healthcare access, customer experience, and community programs. We are seeking a Senior Data Scientist to lead technical initiatives across the entire Lyft Business product suite. In this role, you will shape the technical vision, define algorithmic roadmaps, and drive execution for data science projects that accelerate growth, improve operational efficiency, and deliver measurable value to our enterprise partners. You’ll collaborate closely with Product, Engineering, Design, and Go-to-Market teams to build production ML models, experimentation frameworks, and advanced analytics that inform strategy and power product innovation. This is a high-visibility, high-impact role with direct influence on Lyft’s enterprise offerings. The ideal candidate will bring deep expertise in algorithm development, machine learning, causal inference, and experimentation, alongside strong business acumen in B2B contexts and a proven track record of t

PythonMachine LearningAIGo
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $252K/yr

Quick readStrong listing-quality and freshness signals

Software is eating the world, but AI is eating software. We live in unprecedented times – AI has the potential to exponentially augment human intelligence. Every person will have a personal tutor, coach, assistant, personal shopper, travel guide, and therapist throughout life. As the world adjusts to this new reality, leading platform companies are scrambling to build LLMs at billion scale, while large enterprises figure out how to add it to their products. To make them safe, aligned and actually useful, these models need human evaluation and reinforcement learning through human feedback (RLHF) during pre-training, fine-tuning, and production evaluations. This is the main innovation that’s enabled ChatGPT to get such a large headstart among competition. At Scale, our products include the Generative AI Data Engine, SGP, Donovan, and others that power the most advanced LLMs and generative models in the world through world-class RLHF, human data generation, model evaluation, safety, and alignment. The data we are producing is some of the most important work for how humanity will interact with AI. At the foundation of these products is the Platform Engineering team. In this role, you will lead the design and development of core data storage, streaming, caching, and indexing platforms and underlying systems. You’ll also get widespread exposure to the forefront of the AI race as Scale sees it in enterprises, startups, governments, and large tech companies. You will: Drive the architecture, design, implementation, and reliability of our foundational data platforms and systems, working closely with stakeholders and internal customers to understand and refine requirements. Collaborate with cross-functional teams to define, design, and deliver new features. Proactively identify opportunities for, and driving improvements to, current programming practices, including process enhancements and tool upgrades. Present technical information to teams and stakeholders, providing

MongoDBRedisAWSKubernetes
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $252K/yr

Quick readStrong listing-quality and freshness signals

About Snorkel At Snorkel, we believe meaningful AI doesn’t start with the model, it starts with the data. We’re on a mission to help enterprises transform expert knowledge into specialized AI at scale. The AI landscape has gone through incredible changes since 2015, when Snorkel started as a research project in the Stanford AI Lab, to the generative AI breakthroughs of today. But one thing has remained constant: the data you use to build AI is the key to achieving differentiation, high performance, and production-ready systems. We work with some of the world’s largest organizations to empower scientists, engineers, financial experts, product creators, journalists, and more to build custom AI with their data faster than ever before. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! About Snorkel Snorkel AI is the frontier AI data lab, helping teams build the data and environments behind high-performing frontier and agentic AI. We combine technology with research-driven AI data development to create datasets, benchmarks, evals, and custom solutions for real-world AI systems. Founded out of the Stanford AI Lab in 2019, Snorkel works with leading AI labs and enterprises to move from better data to better outcomes. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! About The Role Snorkel is hiring a Head of Security to build and lead our security function end-to-end — infrastructure security, application security, and governance, risk & compliance (GRC). You'll own the security function end-to-end — strategy, team, and execution — and operate as the primary security voice with customers, auditors, and the exec team. You'll report to the CTO. This is a builder's role: you'll take security from its current state to a mature, right-sized function as Snorkel scales, hiring and developing the team as needs grow. Key Responsibilities Security Leadership & Team Building Define Snorkel's overall security strategy,

AWSCI/CDAIGo
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $170K/yr

Quick readStrong listing-quality and freshness signals

About Snorkel At Snorkel, we believe meaningful AI doesn’t start with the model, it starts with the data. We’re on a mission to help enterprises transform expert knowledge into specialized AI at scale. The AI landscape has gone through incredible changes since 2015, when Snorkel started as a research project in the Stanford AI Lab, to the generative AI breakthroughs of today. But one thing has remained constant: the data you use to build AI is the key to achieving differentiation, high performance, and production-ready systems. We work with some of the world’s largest organizations to empower scientists, engineers, financial experts, product creators, journalists, and more to build custom AI with their data faster than ever before. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! About the Role Snorkel AI is looking for a Head of Talent Acquisition Operations & Insights to build and lead the systems, processes, tools, metrics, and operational infrastructure that power our recruiting organization. This leader will own the design and execution of a modern TA operations function that enables Snorkel AI to scale hiring with speed, quality, consistency, and data-driven decision-making. This is a builder role for someone who has stood up TA operations in a hyper-growth technical startup environment. You should be equally comfortable designing the strategy, implementing the systems, improving process, building reporting, leading recruiting coordination, and partnering with recruiting and business leaders to improve how hiring gets done. We are looking for someone who brings strong operational discipline, deep knowledge of recruiting systems and workflows, and a forward-looking perspective on how AI can modernize talent acquisition. What You’ll Do Build and lead the TA operations function for Snorkel AI, including recruiting systems, tools, workflows, reporting, process, and coordination. Own the recruiting tech stack, including ATS configu

AIGoExcelProject Management
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $130K/yr

Quick readStrong listing-quality and freshness signals

About Snorkel At Snorkel, we believe meaningful AI doesn’t start with the model, it starts with the data. We’re on a mission to help enterprises transform expert knowledge into specialized AI at scale. The AI landscape has gone through incredible changes since 2015, when Snorkel started as a research project in the Stanford AI Lab, to the generative AI breakthroughs of today. But one thing has remained constant: the data you use to build AI is the key to achieving differentiation, high performance, and production-ready systems. We work with some of the world’s largest organizations to empower scientists, engineers, financial experts, product creators, journalists, and more to build custom AI with their data faster than ever before. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! About the Team Marketing at Snorkel is growing rapidly and anchored by high-ownership operators who lead independently, align cross-functionally, and consistently deliver outsized results. We partner across Sales, Product, Research, and the executive team to translate complex AI and data value into differentiated positioning, integrated programs, and field-ready enablement that accelerates growth. The culture is high standards, high autonomy, and high collaboration. About the Role Reporting to the Sr. Director of Product Marketing, the Product Marketing Manager, Frontier Labs will own the GTM execution for our frontier lab business. You will partner closely with Research, FDE, and frontier-facing sales teams to translate technical work into research-credible positioning, repeatable sales plays, and high-quality GTM programs that resonate with research and procurement leaders inside frontier labs. You will keep the frontier asset library (battlecards, technical one-pagers, decks, benchmark and eval narratives) sharp against a fast-moving market, and bring competitive and customer insight into every motion. This is a hands-on role for a product marketer who wants

AIGoExcelMarketing
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $1.3M/yr

Quick readStrong listing-quality and freshness signals

About Snorkel At Snorkel, we believe meaningful AI doesn’t start with the model, it starts with the data. We’re on a mission to help enterprises transform expert knowledge into specialized AI at scale. The AI landscape has gone through incredible changes since 2015, when Snorkel started as a research project in the Stanford AI Lab, to the generative AI breakthroughs of today. But one thing has remained constant: the data you use to build AI is the key to achieving differentiation, high performance, and production-ready systems. We work with some of the world’s largest organizations to empower scientists, engineers, financial experts, product creators, journalists, and more to build custom AI with their data faster than ever before. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! Accounting Manager, Technical Accounting & Financial Reporting San Francisco, CA (Hybrid) About The Role We are seeking a highly motivated Accounting Manager, Technical Accounting & Financial Reporting to play a key role in building and scaling Snorkel's accounting organization. This position combines technical accounting expertise with operational excellence. You will partner closely with the Controller and Accounting team to own key areas of the monthly close, prepare technical accounting analyses, support financial statement audits, and help establish scalable accounting processes and internal controls. The ideal candidate enjoys solving complex accounting issues while remaining hands-on in day-to-day accounting operations. You thrive in a fast-paced startup environment, embrace ambiguity, and enjoy building processes that support a rapidly scaling business. What You'll Do Month-End Close & General Accounting Support and help lead the monthly, quarterly, and annual close processes. Prepare and review journal entries, reconciliations, accruals, and supporting schedules. Perform detailed balance sheet reconciliations and investigate reconcil

AIGoExcelSalesforce
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About Snorkel At Snorkel, we believe meaningful AI doesn’t start with the model, it starts with the data. We’re on a mission to help enterprises transform expert knowledge into specialized AI at scale. The AI landscape has gone through incredible changes since 2015, when Snorkel started as a research project in the Stanford AI Lab, to the generative AI breakthroughs of today. But one thing has remained constant: the data you use to build AI is the key to achieving differentiation, high performance, and production-ready systems. We work with some of the world’s largest organizations to empower scientists, engineers, financial experts, product creators, journalists, and more to build custom AI with their data faster than ever before. Excited to help us redefine how AI is built? Apply to be the newest Snorkeler! The Role We're looking for our founding AI Data Product Manager to own Snorkel's Agentic Data and RL Environments roadmap. In this role, you'll lead the product strategy for a variety of data types (e.g. Agentic Coding, Computer Use). You will shape the roadmap for the datasets Snorkel invests in by understanding the market, incorporating frontier lab needs and collaborating with researchers at Snorkel and our academic partners. This role is highly cross-functional, sitting between Research, GTM and Operations. As a founding member for this role, you will be in charge of setting up the frameworks to build the roadmap, gather data from relevant sources, and share the roadmap with both internal and external stakeholders. What You'll Do Own the "data as a product" roadmap for Snorkel's Agentic and RL Environment focus areas, working x-functionally with research, academic partners, and GTM to define the skills and capabilities for our datasets Shape new "data" product areas and work with academic partners and research leaders to build Snorkel's competitive edge in the market Collaborate cross-functionally to help shape the roadmap and data strategy and influence bu

PythonAIGoExcel
DU
📍 San Francisco, Canada
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the Role At DoorDash we are redefining what it means to be a designer. We are building towards a team of makers, builders, and doers. Between 2005 and 2015, "web designer" became "product designer" and the scope widened. The same shift is happening now — LLMs are expanding the T again, toward strategy on one end and direct execution on the other. As a Staff Product Designer, you will lead this shift across your team: not just practicing build-first design, but multiplying it through the people and systems around you. We're seeking an ambitious and system design minded Staff Product Designer to lead “Meals for Work” within DoorDash for Business , a strategic area at the heart of redefining workplace dining and company perks. You’ll craft transformative consumer and enterprise experiences, from tools that make team lunch ordering effortless to scalable solutions for catering, company paid recurring meals, and grocery benefits. This role offers a unique opportunity to design powerful systems that help workplace admins plan, manage, and operate food programs with confidence, while pioneering new offerings in an evolving market. This position is open for candidates in San Francisco, Seattle, or New York City, and will report to the Head of New Bets Design within our Consumer organization. You will work in a hybrid model, working from one of our offices 1-2 times a week with the rest working from home. Your primary impact is making the team faster and more autonomous. You build reusable workflows, shared tools, and decision frameworks that let every designer on your team operate at a higher level with less coordination overhead. Your secondary impact is revenue: the speed and quality gains you unlock translate directly into more experiments shipped, faster iteration cycles, and measurable business outcomes across your team and adjacent teams. You're excited about this opportunity because you will... Define projects with a clear point of view on what to build,

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