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Lead Product Designer in San Francisco

121 active opportunities · Updated October 2026

Explore current lead product designer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

AT
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$140K – $160K/yr

Quick readStrong listing-quality and freshness signals

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role: Axsome Therapeutics is seeking a National Training Manager to lead and conduct training programs for our Specialty Account Managers. This role is pivotal in ensuring our sales teams are equipped with the knowledge and skills necessary to effectively communicate our product offerings to healthcare professionals. This is a hybrid role that includes both remote and field-based work. This position requires up to 50% travel based on reoccurring national, regional and HQ-based training events, as well as travel to customer field rides with our specialty account team. Job Responsibilities and Duties include, but are not limited to, the following: Conduct all foundational new hire and advanced sales training classes virtually with some in-person sessions Coach and support new specialty account managers in their onboarding Partnering with the HQ based training team and cross functional teams, manage all aspects of training logistics for assigned classes to ensure a se

AIMarketingLogisticsRecruitment
AT
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$140K – $160K/yr

Quick readStrong listing-quality and freshness signals

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role: Axsome Therapeutics is seeking a National Training Manager to lead and conduct training programs for our Specialty Account Managers. This role is pivotal in ensuring our sales teams are equipped with the knowledge and skills necessary to effectively communicate our product offerings to healthcare professionals. This is a hybrid role that includes both remote and field-based work. This position requires up to 50% travel based on reoccurring national, regional and HQ-based training events, as well as travel to customer field rides with our specialty account team. Job Responsibilities and Duties include, but are not limited to, the following: Conduct all foundational new hire and advanced sales training classes virtually with some in-person sessions Coach and support new specialty account managers in their onboarding Partnering with the HQ based training team and cross functional teams, manage all aspects of training logistics for assigned classes to ensure a se

AIMarketingLogisticsRecruitment
V
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$260K – $290K/yr

Quick readStrong listing-quality and freshness signals

About VSCO For years, we've helped photographers create their work. Now we're building what comes next. VSCO exists for photographers. Not as a side feature, not as an afterthought, but as the whole point. We build the connected system photographers rely on, and we've spent over a decade earning the trust of a global creative community that takes the craft seriously. Photography is at an inflection point. AI is reshaping what's possible for creative work, and that's where our mission shines. VSCO is building the full photographer's workflow: from creating and editing your work, to delivering it to clients, to running your business. All of it built thoughtfully, with photographers leading the way. We believe the future of photography tools creates more space for creativity, handling the busy work so photographers can focus on the craft. If you care about craft, community, and what technology can unlock for creative people, this is the work. We're a mission-driven and focused company where your work ships quickly, is meaningful, and reaches tens of millions of people worldwide. You'll have a real say in what we build and how we build it. We hire people who don't wait to be asked, naturally connect the dots, care about the quality of what they ship, and believe the best outcomes come from building together. About The Role VSCO is hiring a Senior Staff Engineer to own Reflex, our production GPU image-processing engine, and the path it takes into Studio Pro on iOS and macOS. This is a critical technical leader. You will deepen a stack that is already in customers’ hands: new capabilities (RAW, large-image export, desktop), production quality (color correctness, memory, performance), and the contracts that let product engineers ship on top of the engine without becoming graphics programmers. You will also lead company-wide engineering mentorship and force-multiplication — tools, workflows, and AI-assisted development that make the rest of the team more effective. In This

ReactRestAIGo
V
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

$150K – $210K/yr

Quick readStrong listing-quality and freshness signals

Location: San Francisco, CA (Hybrid) What is Verse? The race to AI has become the race to power. Every breakthrough in artificial intelligence depends on one thing: access to electricity. But across the country, aging grid infrastructure and years-long interconnection queues are slowing the deployment of the data centers that will power the next generation of innovation. Solving this challenge isn't just about energy—it's about unlocking the future of AI. At Verse, we're building the energy intelligence platform for the AI economy. Our software helps the world's largest energy consumers achieve faster, cheaper, and cleaner power by combining real-time control of energy assets with complete visibility into their energy portfolio. Backed by Bessemer Venture Partners, GV, Coatue, and NVIDIA, and built by pioneers in grid-scale batteries, energy markets, and enterprise software, we're redefining how the world's most ambitious organizations access and manage energy. The Role We're seeking an experienced Senior Optimization Engineer to join our Data Science Team. In this role, you will lead the design, development, and deployment of optimization models that power our software platform across applications including electricity markets, renewable energy, and battery energy storage systems. You will be responsible for developing production-grade optimization engines that solve complex operational and planning problems at scale. This role requires deep expertise in mathematical optimization, strong software engineering skills in Python, and experience building optimization models that integrate with production systems. The ideal candidate has significant experience in the energy industry, particularly electricity markets and battery storage optimization. This position emphasizes technical leadership, ownership of complex optimization projects, and collaboration across engineering, product, and commercial teams to deliver high-impact optimization solutions. Key Res

PythonCI/CDAIGo
R
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $190.8K/yr

Quick readStrong listing-quality and freshness signals

Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . The Media Experience team exists to empower users to discover, consume, and engage with the best media content on Reddit. We do that by making video consumption intuitive and engaging. Because video is a powerful medium for community connection, our goal is to ensure our video experience is best-in-class for every user. Our north star is growing video views and video users . These are users who consistently return to Reddit for the unique, authentic content that fuels our communities. Achieving this level of consistent engagement requires a product flywheel that surfaces the right video features, UI optimizations, and playback improvements at the right moment to accelerate organic engagement. We use data, Quality of Experience (QoE) signals, and rapid product experimentation to identify and resolve any friction preventing a seamless viewing experience. We move with urgency, instrument everything, and treat a missed engagement milestone as a signal to learn from, not a number to ignore. If you want to build iOS video experiences that measurably change the trajectory of tens of millions of users and improve the overall engagement of Reddit itself, this is your team. What you’ll do: 🚀 Drive the Technical Strategy for Media Engagement Lead the iOS architecture for user-facing features that boost video discovery and consumption. You’ll design and build immersive viewing surfaces and intuitive UI/UX flows that directly maximize watch time, user retention, and daily active video consumers. 🔬 Champion for User Experience With

RestAISwiftGo
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $134.4K/yr

Quick readStrong listing-quality and freshness signals

Scale’s Generative AI business unit is experiencing historic growth. As the Community Manager, you will spearhead initiatives connecting hundreds of thousands of expert contributors on our platform. This is a strategic operational role requiring the execution of an operator, program manager, and creative writer. You’ll need an entrepreneurial mindset, operational rigor, and the ability to communicate effectively with diverse stakeholders across internal and external community channels. Scale’s mission is to develop reliable AI systems for the world’s most important decisions. Our Generative AI unit partners with the world's most advanced research teams to improve their models with human data. You will ensure that our global network of contributors stay engaged and informed so that they can do their best work. You will manage communications, execute virtual campaigns and events, and develop strategies to grow and retain our contributor base. This pivotal role shapes community culture, facilitates a thoughtful contributor experience, and harnesses the energy of our community in order to achieve high-level business goals. You must employ creative problem-solving to resolve complex operational challenges and manage the communications cadence across diverse stakeholders. In this role you will: Create strategies to increase participation and satisfaction, overseeing external platforms like Reddit and managing our internal Outlier Community Develop systems to efficiently channel questions, feedback, and disputes across our platforms and social channels Lead with vision: Set direction for multi-team areas and inspire clarity and alignment Organize virtual events to foster connection and monitor community sentiment in order to proactively mitigate risk and address concerns Leverage user feedback, insights, and quantitative metrics to drive improvement in product and operational strategies Enable the team: Instill ownership, drive cross-team collaboration, and remove structur

SQLAWSRestAI
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $275.2K/yr

Quick readStrong listing-quality and freshness signals

Head of Enterprise GTM Strategy & Operations Reports to VP, Enterprise Sales · SF or NY Reporting to the VP of Enterprise Sales, this role owns both halves of Scale AI’s enterprise revenue engine: the strategy that determines where we play and how we win, and the operating system - people, process, and systems - that makes that strategy executable, measurable, and repeatable. On the strategy side, you set the analytical foundation for enterprise growth: segment and account prioritization, coverage and territory design, pricing and packaging inputs, and the diagnostic work that explains why the funnel behaves the way it does. On the operations side, you own the RevOps stack, forecasting, compensation design, sales enablement, and the operating cadences that convert strategy into predictable quarterly execution. The ideal candidate is equally comfortable building a segmentation model from a blank page and running a Monday morning pipeline review. You will lead an established team, with the Head of Sales Enablement and the RevOps Manager as direct reports. Your first job is to raise the ceiling on what that team delivers: sharper analysis, tighter operating rhythm, and enablement that measurably shortens ramp and lifts win rates. This is a senior, highly visible role partnering with Enterprise Sales leadership, Finance, Marketing, Product, and Solutions Engineering, with regular exposure to the executive team and board materials. STRATEGY Define which segments, industries, and accounts Scale prioritizes, and build the analytical case behind those choices Build and maintain the market sizing, segmentation, and account-tiering models that drive coverage decisions and investment trade-offs Lead hypothesis-driven analyses of the enterprise funnel - win/loss patterns, conversion drivers, deal economics, coverage gaps - and translate findings into specific changes to how we sell Partner with Finance and Product on pricing, packaging, and deal-structure strateg

SQLAWSRestAI
NI
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

#Team Nextdoor Nextdoor is where you connect to the neighborhoods that matter to you so you can belong. Our purpose is to cultivate a kinder world where everyone has a neighborhood they can rely on. Neighbors around the world turn to Nextdoor daily to receive trusted information, give and get help, get things done, and build real-world connections with those nearby — neighbors, businesses, and public services. Today, neighbors rely on Nextdoor in more than 350,000 neighborhoods across 11 countries. Meet your Future Neighbors As an Analytics Engineer 4 with Nextdoor, Inc. (San Francisco, CA) (May telecommute from any U.S. location) you’ll: Apply mathematical or statistical theory and methods to design, create, and select the appropriate samples of data that will allow the data science team to conduct probabilistic experiments and statistical analyses Design software systems and processes to gather data in the most efficient way and determine key data points needed in order to interpret experiment results and ensure results are properly tracked Interpret data and report conclusions drawn from their analyses Work with cross-functional teams, including product, design, engineering, marketing, operations, and sales, to determine which data analyses will lead to the most actionable insights Build data pipelines to create and transform data for analysis of different product features Clean and summarize data to make it accessible for reporting and for data science Combine data from multiple sources to make and distribute client reports in order to see how particular ad products are performing Analyze expected vs actual delivery of ad products in order to find and improve gaps in our delivery pipeline What You’ll Bring to The House Master’s degree or foreign equivalent in Mathematics, Statistics, Business Analytics, or closely related quantitative field. Three (3) years of years of experience in the role or in a related position. Full term of experience m

PythonSQLAIRust
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the Team DoorDash’s GenAI Platform team sits within Machine Learning Platform and builds the shared infrastructure that helps DoorDash, Wolt, and Deliveroo teams safely bring GenAI-powered products, agents, automation, and personalization to production. Our mission is to increase the velocity of business impact from GenAI. A central pillar of that work is running frontier open-weight LLMs and VLMs (such as GLM, Qwen, Kimi, and DeepSeek) ourselves — real-time GPU serving, high-throughput batch inference, and fine-tuning on autoscaling GPUs — delivering large cost and latency wins (for example, a billion embeddings produced roughly 20× cheaper and visual models served roughly 72% cheaper). We also own core platform surfaces including the LLM Gateway, Agent Gateway, evals infrastructure, guardrails, and cost attribution. About the Role You will join a small, high-leverage team building production infrastructure for Generative AI at DoorDash, leading the design and architecture of our open-weights model platform spanning inference and fine-tuning: real-time GPU serving, high-throughput batch inference, and model fine-tuning. You’ll set technical direction across model serving and inference engines, fine-tuning and training pipelines, GPU autoscaling and utilization, batch pipelines, backend services, and observability, and mentor engineers as you go. This role is ideal for a senior engineer who enjoys owning ambiguous, high-impact systems and pushing the cost/performance frontier of GPU inference and fine-tuning in a fast-moving technical area where product needs, model capabilities, vendor ecosystems, and cost/performance tradeoffs are evolving quickly. You’re excited about this opportunity because you will… Lead the design of infrastructure that helps DoorDash teams move GenAI ideas from prototype to production, increasing the velocity of business impact from AI across the company. Own and evolve our open-weights serving stack — real-time GPU endpoints, high-thr

PythonAWSGCPKubernetes
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $1.5M/yr

Quick readStrong listing-quality and freshness signals

About the Team AI Research Lab is one of DoorDash’s frontier innovation hubs, focused on building the foundation for an AI-native future across our three core audiences: consumers, merchants, and dashers. As AI capabilities accelerate, the AI Research Lab operates at the center of technical exploration and real-world execution — connecting frontier model research, internal platform investments, operator teams, and strategic external partners. Our mission is to translate cutting-edge AI research into scalable, production-ready systems that drive measurable business impact. We combine deep technical rigor with strong operational execution to ensure that breakthrough capabilities become durable competitive advantages for DoorDash. About the Role As an Associate Manager, Strategy & Operations on our AI Research Lab, you will play a central role in converting frontier AI advancements into shipped products and scalable infrastructure. You will operate across research, product, and operations to move from early discovery and experimentation to deployment and impact. This role sits at the intersection of customer insight, technical innovation, and business execution. You will help define and scale the Lab’s most important bets while building the foundations that enable AI applications to compound over time. You’re Excited About This Opportunity Because You Will … Reimagining core experiences through AI, such as the merchant journey, by partnering directly with in-field merchants, sales, support, product, and engineering teams. You will help unify major initiatives into a coherent, AI-native interaction model. Own revenue-driving AI initiatives, operating as the accountable business owner for high-priority AI bets and ensuring clear linkage between technical progress and financial outcomes. Lead business planning cycles, developing go-to-market strategies for AI-powered products and capabilities, overseeing execution through structured project plans, resource allocation,

AWSGitRestAI
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $1.3M/yr

Quick readStrong listing-quality and freshness signals

About the Team The New Verticals Business Development team is a small, fast-paced, high-performing group responsible for establishing, managing and scaling new lines of business at DoorDash in the retail and logistics space. You’ll leverage AI-powered insights, data-driven signals, and emerging tools to shape strategy, inform decision-making, identify opportunities, and drive growth across complex, enterprise-level engagements. By integrating AI and data-enabled analysis into day-to-day workflows, you’ll improve prioritization, execution, and business impact while partnering cross-functionally to translate evolving platform and AI capabilities into clear, tangible value for partners and the business. About the Role Your role will be focused on building out a team while managing and scaling enterprise level partnerships in the retail and logistics space. This role will get you in at the ground floor and operate at “start up” pace for one of DoorDash’s fastest and most promising new bets. As Associate Manager, Retail Partnerships you will report into the Senior Manager of Retail Partnerships in our Merchant Business Development organization. You’re excited about this opportunity because you will… Manage and cultivate enterprise relationships with leading retailers and ecommerce logistics players that will drive step change growth for DoorDash Lead renewals and upsell opportunities with existing merchant partners Shape product roadmap and go-to-market strategies based on merchant feedback Serve as the liaison between our partners and DoorDash leadership, product, legal, operations, and logistics teams Inform goals for growth and revenue (and its proxies); and advise on associated business resource needs Identify and pursue creative growth opportunities within the Drive organization We’re excited about you because… You have 8+ years experience in early stage business development, account management, client success, or strategic partnerships in technology or

AWSGitRestAI
DU
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $1M/yr

Quick readStrong listing-quality and freshness signals

About the Team The Enterprise Ad Sales Team is responsible for the marketing vision, development and growth of our largest advertising partnerships. This team was recently formed, and is seeking additional founding team members to build an industry-leading ads and promotions business across DoorDash’s core categories, starting with enterprise restaurant and consumer packaged goods (CPG) brands. The growing DoorDash ads business will quickly become the single best place for merchants and brands to market to local customers, in an ecosystem that benefits all parties. You’ll leverage AI-powered insights, data-driven signals, and emerging tools to shape strategy, inform decision-making, identify opportunities, and drive growth across complex, enterprise-level engagements. By integrating AI and data-enabled analysis into day-to-day workflows, you’ll improve prioritization, execution, and business impact while partnering cross-functionally to translate evolving platform and AI capabilities into clear, tangible value for partners and the business. About the Role The Account Manager, CPG will steer the company's efforts in adopting and partnering with major CPGs across our grocery, convenience, restaurant and retail markets. Digital grocery and convenience is expanding, and DoorDash is making meaningful strides to become a leader in this sector. You will build partnerships that create tangible value for both DoorDash and advertisers. In this role, you will manage the ads strategy across a focused portfolio of accounts, and drive adoption of our growing ads and promotions offering. You will also work cross-functionally with account executives, marketing, analytics, and product to innovate on our future approach and solutions. You will report into a CPG Industry Manager in our Enterprise Sales & Business Development organization. You’re excited about this opportunity because you will… Be part of the growing DoorDash Ads & Promos team Lead end-to-end marketing conversa

AWSGitRestAI
S
📍 San Francisco, Canada
✓ Quality checkedCompany trend -91.4%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team The Strategic Pursuits team is a new group within Stripe’s Enterprise Platform Sales organization, built to win Stripe’s most complex and high-impact opportunities. This team focuses on multi-year, transformative sales cycles with the world’s largest software platforms and enterprises—companies that have the potential to fundamentally shift Stripe’s presence in new industries and markets. Strategic Pursuits is responsible for identifying, shaping, and closing Stripe’s most significant platform partnerships. These are long, intricate engagements requiring deep collaboration across executive, product, and engineering teams and the ability to influence strategic priorities on both sides of the table. The team’s work often extends well beyond payments, helping partners co-develop entirely new business models and revenue streams powered by Stripe’s financial infrastructure stack, including Connect, Billing, Payments, and Banking as a Service. What you’ll do As an Account Executive, Strategic Pursuits , you will lead the end-to-end pursuit of Stripe’s largest and most complex platform opportunities. You’ll act as both strategist and dealleader—identifying transformative prospects, crafting multi-year engagement plans, and orchestrating resources across Stripe to bring highly tailored solutions to market. This is a senior, cross-functional sales role that combines strategic vision

Q
📍 San Francisco, Canada· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

At Qualia, we've built the leading B2B real estate technology that transforms the home buying and selling experience into a simple, secure, and enjoyable process. Our SMB and Enterprise products bring together users from across the real estate ecosystem---homebuyers and sellers, lenders, title and escrow agents, and real estate agents---onto a single shared digital closing platform, providing greater clarity and transparency to real estate transactions. Today, through our business customers across the country, millions of consumers use Qualia to close on homes every year. WHAT YOU'LL WORK ON The FP&A team at Qualia is the analytical engine of the Finance organization. We own the company's planning and forecasting processes, serve as trusted business partners to functional leaders, and produce the financial insights that inform our most important strategic decisions, all in an environment where AI is actively reshaping how we work. As a Senior Manager of FP&A, you will be a central force in shaping how Qualia plans, forecasts, and makes decisions as we scale. You will own high-impact analytical workstreams end-to-end, serve as the go-to financial partner for senior functional leaders, and help set the direction for how the FP&A function evolves, from the models we build to the processes we run to the way we leverage AI to work smarter. This is a high-visibility individual contributor role with direct exposure to executive and C-level audiences. RESPONSIBILITIES Own Qualia's planning and forecasting infrastructure : Lead the design, build, and continuous improvement of our operating model, annual plan, and long-range financial plan, ensuring they accurately reflect the current and future state of the business Drive financial rigor at the executive level: Lead preparation of monthly and quarterly management reporting, Board materials, and investor-facing financial packages; distill complex financial results into clear narratives that drive action at the lea

GitAIGoRust
SA
📍 San Francisco, Canada· Full-time
✓ High-confidence listing

From $252K/yr

Quick readStrong listing-quality and freshness signals

Software is eating the world, but AI is eating software. We live in unprecedented times – AI has the potential to exponentially augment human intelligence. Every person will have a personal tutor, coach, assistant, personal shopper, travel guide, and therapist throughout life. As the world adjusts to this new reality, leading platform companies are scrambling to build LLMs at billion scale, while large enterprises figure out how to add it to their products. To make them safe, aligned and actually useful, these models need human evaluation and reinforcement learning through human feedback (RLHF) during pre-training, fine-tuning, and production evaluations. This is the main innovation that’s enabled ChatGPT to get such a large headstart among competition. At Scale, our products include the Generative AI Data Engine, SGP, Donovan, and others that power the most advanced LLMs and generative models in the world through world-class RLHF, human data generation, model evaluation, safety, and alignment. The data we are producing is some of the most important work for how humanity will interact with AI. At the foundation of these products is the Platform Engineering team. In this role, you will lead the design and development of core data storage, streaming, caching, and indexing platforms and underlying systems. You’ll also get widespread exposure to the forefront of the AI race as Scale sees it in enterprises, startups, governments, and large tech companies. You will: Drive the architecture, design, implementation, and reliability of our foundational data platforms and systems, working closely with stakeholders and internal customers to understand and refine requirements. Collaborate with cross-functional teams to define, design, and deliver new features. Proactively identify opportunities for, and driving improvements to, current programming practices, including process enhancements and tool upgrades. Present technical information to teams and stakeholders, providing

MongoDBRedisAWSKubernetes
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