Clinical Research Scientist

Noctrix Health is redefining the treatment of chronic neurological disorders with clinically validated therapeutic wearables. Our team of medical device specialists, neuroscientists, and consumer electronics engineers is dedicated to delivering prescription-grade therapy with an outstanding user experience. We have pioneered the world’s first drug-free wearable therapy, clinically proven to alleviate symptoms in adults with drug-resistant Restless Legs Syndrome (RLS). Be part of our mission to transform healthcare, improve lives, and drive meaningful change with Noctrix Health. We are seeking an experienced and hands-on Senior Clinical Research Scientist to lead the strategy and execution of clinical research supporting the development and validation of emerging therapeutic technologies. This role will have direct responsibility for study design and analysis, physiological data collection, algorithm development, external research collaborations, and the communication of scientific findings through grants, publications, and conference presentations. The ideal candidate is a highly collaborative scientist who is equally comfortable developing research strategy and working directly with engineering, clinical affairs, investigators, and research partners to execute studies and solve complex scientific problems. This individual will play a critical role in translating physiological and clinical data into meaningful product insights, clinical evidence, and future research opportunities. This is a full-time, hybrid position based in Pleasanton, CA, with a minimum of three days onsite per week, or more depending on business needs. Travel is expected to be approximately 10%. Responsibilities Design and lead the execution of multiple clinical research studies in parallel Lead the analysis and interpretation of physiological and clinical data sets Develop research strategies, study plans, protocols, case report forms, and statistical analysis plans that produce scientifically

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 115,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Clinical Research Associate II Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution. Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Opportunity The CRA II will assist in the clinical execution and management of all aspects of assigned clinical studies. This includes but not limited to planning and implementati

Become a part of our caring community Humana’s Quality and Cost Strategy Analytics Team is seeking a Research Scientist 2 (Remote). Healthcare is rapidly changing, and our members are living longer, often with more chronic conditions. The Quality and Cost Strategy Analytics team identifies opportunities and build solutions to improve clinical outcomes and lower costs for millions of Medicare Advantage beneficiaries leveraging data science & analytics, clinical expertise, strategic mindset, and rigorous study designs. In this multi-disciplinary team, you will have the opportunity to work closely with strategy partners and clinicians to shape Humana’s future enterprise clinical strategies and initiatives. The Research Scientist 2 will lead research, evaluation and development of opportunities that optimize healthcare delivery, lower medical cost while improve member health outcomes, through applying mathematical, statistical, epidemiologic and data science methods. The Research Scientist 2 will also partner with stakeholders across the enterprise to identify, prioritize and measure the impact of core and novel solutions to significant problems in healthcare and improve the health of especially underserved population, using high volumes of structured and unstructured data. Responsibilities As a Research Scientist 2, you will: Research, prototype and scale new ideas to improve population health and healthcare delivery Collaborate with analytic and business teams to set objectives, approaches, and work plans Collaborate with strategy to evaluate existing programs and identify and measure new solutions to impact healthcare Leverage a wide range of analytics methods ranging from descriptive to prescriptive to transform high volumes of complex data into analytics solut

Use Your Power for Purpose At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development team, which strives to convert advanced science and cutting-edge technologies into impactful therapies and vaccines. Whether you are engaged in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, your role is crucial. You will leverage innovative design and process development capabilities to expedite the delivery of top-tier medicines to patients globally. Role Summary Pfizer’s Machine Learning and Computational Sciences (MLCS) group is seeking a Senior Machine Learning Scientist to lead independent and collaborative research in computational antibody design and optimization. This position focuses on developing and applying modern computational and machine-learning approaches to accelerate the discovery of next-generation biologic therapeutics. Positioned at the intersection of machine learning, protein science, and therapeutic discovery, the role is ideal for candidates eager to translate foundational AI research into real-world drug design. It offers the opportunity to join an innovative, collaborative environment that supports professional growth through mentorship, knowledge sharing, and the freedom to pursue impactful science. What You Will Achieve In this role, you will: Conduct original research in computational antibody engineering, with an emphasis on sequence- and structure-based generative modeling. Develop and deploy state-of-the-art machine-learning methods for multi-objective, constraint-aware antibody optimization that balances affinity, stability, and developability. Apply proprietary computational frameworks and machine-learning models to predict antibody developability and affinity. Leverage NGS-derived antibody repertoires to info

Responsible for the scientific and clinical oversight of clinical trials in support of the development strategy for programs within the Inflammation & Immunology (I&I) portfolio. As an individual contributor, this role focuses on ensuring data integrity and quality for clinical trials across both early and late-stage development, based on portfolio and resourcing needs. The Senior Manager partners with other clinical and medical colleagues, clinical operations, and other functional lines for the successful implementation and execution of the clinical trial(s) within the assigned program. This role is central to ensuring studies are conducted with the highest scientific and ethical standards. The role is also expected to leverage AI tools and other innovative technologies to improve ways of working, enhance efficiency, reduce work redundancy and improve quality. JOB RESPONSIBILITIES Maintains current scientific and clinical knowledge in the specific therapeutic and disease area(s) of assignment. Authors and reviews key clinical and regulatory documents including, but not limited to, protocols, study-level informed consent forms (ICFs), Investigator's Brochures (IBs), clinical study reports (CSRs), and regulatory submission components. Leads the clinical data review strategy, including the ongoing review of emerging clinical data for safety and efficacy trends. Presents relevant data to internal teams, governance bodies, and other stakeholders. Collaborates with cross-functional team members (e.g., Clinical Operations, Biostatistics, Regulatory Affairs, Clinical Pharmacology) to ensure trial objectives are met and activities are executed seamlessly. Provides scientific and clinical input for site training materials and supports responses to questions from investigators and site personnel regarding the protocol and study conduct.

POSITION SUMMARY: Natera is a global leader in cell-free DNA testing. We measure fetal, tumor, or donor cfDNA at the molecular level to help inform personalized health care decisions with a non-invasive test. The Natera R&D Department is looking for a highly motivated Senior Scientist to join the rapidly growing assay development team to help build the future of Natera. In this position, you will be an integral part of high-performing teams across functions to develop laboratory tests that positively impact the business and our patients. A successful candidate will have a deep understanding of molecular biology, strong scientific curiosity and high level of expertise of developing cfDNA assays through product development cycles. You will lead and support dedicated junior scientists and laboratory technicians to plan, execute and manage scientific studies under design control in a regulated environment to help improve and expand Natera's state-of-the-art product portfolios. PRIMARY RESPONSIBILITIES: Lead technical projects and associated timelines and deliverables as a subject matter expert and represent the assay development group in cross-functional project teams. Drive the planning, design, execution, and reporting of feasibility, development, verification and validation studies under the design control quality system. Collaborate closely with research scientists, automation engineers, biostatisticians and data scientists within a dynamic R&D team to develop new and innovative molecular assays. Communicate and document experimental data, scientific findings, and recommendations to R&D and other functions including Lab Operations, Scientific Affairs, Product Management, Quality, and Regulatory groups. May manage Research Associates. QUALIFICATIONS: Typically requires a university degree and a minimum of 8+ years of related experience or a MS degree and 6 years of related experience or a PhD and 4 years of related experience Knowledge of high throughput