$106K – $176.6K/yr
Use Your Power for Purpose At Pfizer, our purpose is to deliver breakthroughs that transform patients' lives. Central to this mission is our Research and Development team, which strives to convert advanced science and cutting-edge technologies into impactful therapies and vaccines. Whether you are engaged in discovery sciences, ensuring drug safety and efficacy, or supporting clinical trials, your role is crucial. You will leverage innovative design and process development capabilities to expedite the delivery of top-tier medicines to patients globally. Role Summary Pfizer’s Machine Learning and Computational Sciences (MLCS) group is seeking a Senior Machine Learning Scientist to lead independent and collaborative research in computational antibody design and optimization. This position focuses on developing and applying modern computational and machine-learning approaches to accelerate the discovery of next-generation biologic therapeutics. Positioned at the intersection of machine learning, protein science, and therapeutic discovery, the role is ideal for candidates eager to translate foundational AI research into real-world drug design. It offers the opportunity to join an innovative, collaborative environment that supports professional growth through mentorship, knowledge sharing, and the freedom to pursue impactful science. What You Will Achieve In this role, you will: Conduct original research in computational antibody engineering, with an emphasis on sequence- and structure-based generative modeling. Develop and deploy state-of-the-art machine-learning methods for multi-objective, constraint-aware antibody optimization that balances affinity, stability, and developability. Apply proprietary computational frameworks and machine-learning models to predict antibody developability and affinity. Leverage NGS-derived antibody repertoires to info