Model Policy, Chemical & Biological Risk

About the Team The Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. The Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. Key focus areas include: catastrophic risk, mental health, teen safety and multimodal safety. About the Role Providing access to frontier AI systems raises complex questions around dual-use science and catastrophic risk. How should models respond to requests involving chemical synthesis, biological experimentation, or pathogen research? Where is the boundary between legitimate scientific inquiry and information that could enable misuse? How do we design policies that meaningfully reduce risk without unnecessarily restricting beneficial research? This is a senior role in which you’ll help shape policy creation and development at OpenAI for addressing biological and chemical risks. You will develop structured policy frameworks and taxonomies to guide safe model behavior. This role sits at the intersection of biosecurity expertise, AI safety research, and policy design. You will help ensure that frontier AI systems can support beneficial life sciences research, such as drug discovery, public health, and biosafety, while reducing the risk that these capabilities could be misused. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you’ll: Design and maintain model policies governing chemical and biological risk, defining how models should safely handle dual-use scenarios. Develop structured taxonomies of chemical and biological risk that inform model training data, evaluation benchmarks, and safet

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. Within Safety Systems, the Model Policy team works to ensure that frontier models behave safely and reliably in real-world environments by designing policies that define safe model behavior. Some of our publications include: Safety at every step OpenAI GPT6 System Card OpenAI Model Spec About the Role We’re hiring a Model Policy Manager to shape model behavior for U.S. government use, with a focus on national security applications. You’ll define nuanced policies and translate them into training and evaluation criteria, helping models navigate high-stakes scenarios while preserving their usefulness and capabilities. In this role, you will: Develop model policies that guide safe and useful behavior. Build evaluations, identify policy gaps and model failures, and use findings to improve policies and training. Work with research, engineering, and domain experts to support safe, reliable deployment. You might thrive in this role if you: Bring relevant experience in AI safety, policy, or risk assessment. Have strong judgment and can turn complex safety questions into clear, practical policies. Have the technical fluency to work hands-on with model data and evaluations. Are motivated by OpenAI’s mission and the responsible use of

About the Team Safety Systems manages the complete lifecycle of safety efforts for OpenAI’s frontier models, ensuring our models are deployed responsibly and have a positive impact on society. Our work spans diverse research and engineering initiatives—from system-level safeguards and model training to evaluation and red-teaming—all aimed at mitigating misuse, misalignment, and maintaining our high bar for safety. We lead OpenAI's commitment to developing and deploying safe Artificial General Intelligence (AGI), fostering a culture of trust, responsibility, and transparency. Our goal is to continuously learn from deployments, distribute AI’s benefits widely, and ensure that powerful tools remain aligned with human values and safety considerations. Within Safety Systems, the Model Policy team works to ensure that frontier models behave safely and reliably in real-world environments by designing policies that define safe model behavior. Our relevant publications include: Safety at every step OpenAI GPT6 System Card OpenAI Model Spec GPT-Live ChatGPT Images 2.5 About the Role We are hiring a Model Policy Manager to focus on the safety of multimodal models. In this role, you will shape how OpenAI identifies, evaluates, and addresses risks in multimodal AI models - such as GPT-Live and ChatGPT Images - as well as multimodal capabilities in frontier AI models. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Design and maintain model policies for audio, image, video, and omni-modal behavior. Translate theories of harm and threat models into behavioral safety policies, evaluation criteria, grading guidance, and safeguards. Identify and analyze safety regressions and failure patterns to identify gaps in existing policies and inform policy iteration. Develop policy artifacts that support model training, evaluation, and deployment, including behavior i

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. Within Safety Systems, the Model Policy team works to ensure that increasingly capable models behave safely and reliably in real-world environments. We investigate emerging model failures, define the behavior models should exhibit instead, and develop the data, evaluations, monitoring, and safeguards needed to improve and validate that behavior. Our work connects alignment research with the practical challenges of training and deploying frontier models. About the Role In this role, you will shape how OpenAI understands and addresses real-world risks that emerge from model misalignment as models become more autonomous and operate over longer horizons. You will investigate how misaligned behavior emerges across extended trajectories - including when models persist toward the wrong objective, take unsafe shortcuts, lose track of instructions, exploit weaknesses in their environment, or circumvent constraints - and translate these insights into behavioral policies, evaluations, monitoring, and safeguards. This role is ideal for someone who wants to turn alignment and safety concerns into concrete, empirically grounded improvements to frontier AI systems. Your Responsibilities: Identify vulnerabilities that emerge as models interact with tools, data, and external systems, and translate them into model- and system-level safeguards. Develop threat models and empirical frameworks for understanding harmful outcomes from misaligned behavior. Build frameworks for understanding harmful outcomes arising from model misalignment. Identify the underlying behaviors and system conditions that drive those outcomes. Turn findings into policy frameworks, evaluation criteria, online measurement and safeguards. Develop human data campaigns and gold sets to ground measurement and evaluation of eme

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. Within Safety Systems, the Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. About the Role Frontier AI systems are rapidly expanding what is possible in cybersecurity and software engineering. These capabilities create major defensive opportunities, but they also raise serious dual-use and misuse risks across areas such as malware development, exploit discovery, vulnerability chaining, credential abuse, cyber intrusion, and autonomous offensive operations. In this role, you will help define how OpenAI’s models should behave in high-risk cybersecurity contexts. You will develop policy frameworks, threat models, taxonomies, evaluations, and behavioral specifications that guide model behavior across training, deployment, and monitoring systems. This role sits at the intersection of cybersecurity, AI safety, threat modeling, evaluation science, and policy implementation. You will work closely with research, engineering, safety training, preparedness, and product teams to build policies that are technically grounded, measurable, enforceable, and responsive to real-world cyber risk. Your Responsibilities: Design and maintain model policies for cybersecurity and frontier-risk domains, especially dual-use and high-risk cyber capabilities. Translate cybersecurity threat models into clear behavioral specifications, evaluation criteria, grading guidance, and system-level mitigations. Define practical boundaries between legitimate security research, defensive workflows, and assistance that could materially enable harmful activity. Build policy artifacts that support i

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. We believe that achieving our goal requires effective engagement with public policy stakeholders and the broader community impacted by AI. Accordingly, our Global Affairs team builds authentic, collaborative relationships with public officials and the broader AI policymaking community to inform and support our shared work in these domains. We ensure that insights from policymakers inform our work and – in collaboration with our colleagues and external stakeholders – seek to shape policy so that it aligns with and supports our mission. About the role OpenAI is looking for an Applied Risk Standards Specialist to lead standards work for applied risk in applications, including mental health, youth safety, age assurance, functional efficacy, reliability, and privacy-related risks. You will help turn internal research, safety policies, and evaluation methods into technically sound, measurable, and adaptable standards that build public trust and support responsible deployment. This role sits within our AI standards and global assurance function in Global Affairs. Working closely with Safety Systems, Research, Product, Model Policy, Legal, and third-party evaluators, you will author proposals, negotiate requirements, and represent OpenAI in priority standards bodies. You will take on the drafting and external engagement needed to advance this work, enabling technical experts to focus on the underlying methods and evidence. You will also bring emerging requirements back into internal planning before they become established expectations. Alongside this primary portfolio, you will support the AI Standards and Global Assurance Lead on frontier AI assurance, contributing to risk-management standards, evaluation and benchmarking requirements, and approaches to independent assessment. The role connects technical practice with external standards. It does not replace t