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Active1d ago

Principal AI Engineer

Natera·📍 Us-Remote, Canada

Employment

Full-Time

Work mode

Remote

Experience

SENIOR LEVEL

Salary

Not disclosed

Salary not disclosed

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Role overview

Job description

POSITION SUMMARY Natera is seeking a Principal AI Engineer to set technical direction for, and hands-on build of, the Vector Store GenAI Platform that powers document intelligence and retrieval across our Real-World Data (RWD) organization. The platform ingests clinical documents from multiple sources, indexes them for high-quality search, and makes that content available to downstream AI workflows and business use cases across oncology and other clinical domains. This is a principal-level individual contributor role with architecture-plus-build ownership of retrieval, document processing, and ingestion systems. You will define platform strategy and sequencing, ship production code in a cloud environment, raise the reliability and quality of search and retrieval, and prove new approaches through POCs and benchmarks. You will partner with clinical, engineering, and product leaders to turn

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What they are looking for

Skills & requirements

Qualification

Integrate LLM capabilities into existing production systems with attention to performance, scalability, cost, observability, and safe operation in a regulated environment; QUALIFICATIONS Bachelor’s or Master’s degree in Computer Science, Engineering, or a related technical field; an advanced degree or background in a clinical or life sciences discipline is a plus; 5+ years building and shipping AI/ML-powered applications in production, with deep hands-on experience in retrieval-augmented systems, vector search, and document-centric AI pipelines—including indexing, retrieval quality, evaluation, and integration with downstream LLM or agent systems; Experience designing retrieval interfaces used by agents or multi-step LLM workflows is a plus

Department · Engineering RWD

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Hiring company

Natera

Dedicated to oncology, women’s health, and organ health. Natera’s cell-free DNA tests help protect health and inform more personalized decisions about care.

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