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Active4w ago

Principal AI Systems Engineer

Employment

Full-Time

Work mode

Remote

Experience

SENIOR LEVEL

Salary

$175K – $200K/yr

Role overview

Job description

About Iovance Biotherapeutics, Inc. Iovance Biotherapeutics , Inc.  is the global leader in innovating, developing, and delivering tumor infiltrating lymphocyte (TIL) cell therapies for patients with solid tumors. Amtagvi® (lifileucel) is the first FDA-approved, one-time treatment for previously treated advanced melanoma, now approved in three global markets and available at more than 95 authorized treatment centers. The Iovance TIL platform spans registrational trials and next-generation programs in additional solid tumors, including gene-edited and IL-12 tethered TIL therapies, next-generation IL-2, and precision immuno-oncology approaches. As the first and only company to take TIL therapy from concept to a broadly accessible commercial treatment, Iovance operates as an end-to-end cell therapy company, anchored by fully owned, centralized U.S.-based manufacturing that is scaled to s

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What they are looking for

Skills & requirements

Qualification

The ideal candidate is a deeply technical, hands-on senior engineer with demonstrated production experience designing and shipping Large Language Model (LLM) applications, Retrieval-Augmented Generation (RAG) systems, and modern AI integrations; Own and maintain LLM security controls for production AI systems, including input and output guardrails, prompt injection and jailbreak defenses, sensitive data redaction (PII, PHI, Iovance Confidential Information and Intellectual Property), content moderation, and abuse monitoring, working in partnership with IT Security; Qualifications 10+ years of progressive software and/or AI/ML engineering experience, with the most recent 1+ years dedicated primarily to LLM-based application development

Department · Information Technology

Iovance Biotherapeutics logo

Hiring company

Iovance Biotherapeutics

Learn about our investigational tumor infiltrating lymphocyte (TIL) therapy. View our clinical trials and pipeline.

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