Opportunity Overview: We’re seeking a Senior Clinical Informatician to serve as a key bridge between clinical expertise and data science. In this advanced role, you’ll apply deep clinical reasoning and informatics expertise to design, evaluate, and optimize data-driven healthcare solutions. You’ll also lead ontology mapping, structured data validation, and annotation quality initiatives supporting our next-generation AI and LLM-enabled healthcare tools. This is a remote-first role that may require travel to Boston, MA for new hire onboarding and occasional in-person team meetings and company events. What you’ll do: Collaborate with clinicians, data scientists, and engineers to design and validate digital health and analytics solutions. Translate clinical workflows into structured data and logic for algorithms and quality measurement. Lead efforts in ontology mapping, terminology management (SNOMED, ICD, LOINC, RxNorm), and interoperability standards (FHIR, HL7). Oversee labeling and abstraction to ensure model safety, accuracy, and clinical integrity. Mentor junior informaticians and specialists in annotation, data validation, and workflow improvement. What you’ll need: BSN or related clinical degree with active RN license required. 4–6+ years of experience in clinical informatics, analytics, or digital health. Advanced understanding of clinical data, EHR systems, and data standards. Experience with data modeling or AI-driven healthcare products preferred. Master’s degree or informatics certification (RN-BC, CPHIMS, ACHIP, etc.) a plus. Pay & Perks: 💻 Fully remote opportunity with about 5% travel 🩺 Medical, dental, vision, life, disability insurance, and Employee Assistance Program 📈 401K retirement plan with company match; flexible spending and health savings account 🏝️ Up to 184 hours (23 days) of PTO per year + company holidays 👶 Up to 14 weeks of paid parental leave 🐶 Pet insurance The salary range for this p
Market pay estimate
$199,950–$260,450 / year for comparable Data Scientist roles in United States. Not employer-provided.
Role overview
Job description
The Ontology Engineer is a foundational technical hire on the AI, ML and Data Science team specializing in Knowledge Representation. This role is responsible for designing and maintaining the formal ontological architecture that makes cross-organizational data alignment. This is not a taxonomy or metadata management role. It requires genuine formal depth in description logics, upper ontology theory, and the ability to reason about what an ontology commits to and what it leaves open. Our platform sits between hospitals, distributors, GPOs, manufacturers, and regulators, enabling transactional execution, clinical data alignment, and analytics optimization across organizational boundaries. Each party maintains its own implicit ontology encoded in its schemas, workflows, and data. The Ontology Engineer will define the formal structures and processes that make alignment across them possible.
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They will be expected to make and defend design decisions at the level of formal correctness, not just practical convenience, and to direct and evaluate LLM-assisted ontology discovery and enrichment pipelines with the rigor that formal alignment demands; Build, direct and evaluate LLM-assisted ontology extraction pipelines, define and enforce the human-in-the-loop validation standards for AI-generated ontological candidates; Proactively monitor developments in formal ontology, knowledge representation, and LLM-assisted knowledge engineering to drive adoption of improved methods; Familiarity with LLM-assisted ontology extraction and enrichment pipelines, including the ability to evaluate LLM-generated ontological candidates against formal
Department · Artificial Intelligence

Hiring company
GHX
GHX: It's the way you do business in healthcareGlobal Healthcare Exchange (GHX) enables better patient care and billions in savings for the healthcare community by maximizing automation, efficiency and accuracy of business processes. GHX is a healthcare business and data automation company, empowering healthcare organizations to enable better patient care and maximize industry savings using our world class cloud-based supply chain technology exchange platform, solutions, analytics and services. We bring together healthcare providers and manufacturers and distributors in North America and Europe - who rely on smart, secure healthcare-focused technology and comprehensive data to automate their business processes and make more informed decisions. It is our passion and vision for a more operationally efficient healthcare supply chain, helping organizations reduce - not shift - the cost of doing business, paving the way to delivering patient care more effectively. Together we take more than a billion dollars out of the cost of delivering healthcare every year. GHX is privately owned, operates in the United States, Canada and Europe, and employs more than 1000 people worldwide. Our corporate headquarters is in Louisville, Colorado, just outside of Denver, with additional offices in Europe, Chicago, Illinois, and Omaha, Nebraska. Read our GHX Privacy Policy
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