Senior Director, Development - ECD and MCED Products

POSITION SUMMARY: The Senior Director, Laboratory Operations is responsible for the management and oversight of all aspects of operations in order to provide the highest quality service including: clinical laboratory and laboratory operations. Knowledge of CAP, CLIA, California, and New York state regulations. PRIMARY RESPONSIBILITIES: Develop policies, procedures, and performance standards to ensure efficiency and quality. Ensure efficient and customer-friendly service. Oversee all clinical and technical functions of laboratory, which includes: day-to-day production, equipment and reagent qualification, and training. Lead trouble-shooting teams to address urgent issues. Ensure that operations maintain all personnel, equipment and consumable resources necessary to match the demand and projections. Maintain and expand laboratory infrastructure, including personnel, equipment, and inventory. Ensure efficient and effective use of resources and personnel within laboratory. Lead process improvements throughout the laboratory. Operationalize and implement new product launches. Maintain the resources required for effective turnaround times for all patient testing. Organize training and development programs for laboratory and support staff. Work with senior leadership to execute on short and long-term strategy. Recruit, retain, train, and develop employees and conduct performance management activities. Develop a team-oriented culture within and between departments. This role works with PHI on a regular basis both in paper and electronic form and have an access to various technologies to access PHI (paper and electronic) in order to perform the job. Employee must complete training relating to HIPAA/PHI privacy, General Policies and Procedure Compliance training and security training as soon as possible but not later than the first 30 days of hire. Must maintain a current status on Natera training requirements. QUALIFICATIONS: BS/BA (or equivalent) in a biological scien

POSITION SUMMARY Works closely with Senior Manager to ensure company, department, and team goals are met. PRIMARY RESPONSIBILITIES • Monitors workflow and ensures production goals and deadlines are met (e.g. TAT, SLA) • Engages in future planning and scales employees and equipment appropriately • Gathers and monitors metrics on production deadlines, efficiency, scrap waste, and error rates • Monitors the quality control/assurance programs, test results, and equipment (if applicable) • Uses metrics in decision-making and to drive changes across the team (e.g. cost reduction, quality improvement) • Manages sufficient headcount levels to meet production goals by proactively driving the interview process and managing employee PTO and overtime when necessary. • Refines current lab process through continuous improvement projects. • Oversees team specific lab operation. • Go-to person when senior manager is not present; go-to person for knowledge of process and product. • Responsible for seamless transition of automation and test improvement/additions into production workflow • Analyzes and troubleshoots lab processing errors; provides recommendations on how to proceed to lab director, scientists and statisticians as necessary • Supports Supervisors in close out of NCRs. • Responsible for the initiation and close out of CAPAs in a timely manner. • Ensures departmental lab compliance for regulatory bodies • Ensures tests are being completed according to approved procedures. • Maintains an organized, safe and efficient work area for the team at all times. • Actively interacts with interdepartmental teams such as OPS, Accessioning, Engineering, Stats, R&D, and Support. • Handles employee issues: complaints, disciplinary actions, etc. Collaborates with Senior Manager and/or Human Resources to resolve issues. • Explains (as much as possible) reasoning behind instructions/processes given/changes that are made. If necessary, explains to team why certain ideas cannot be implem

Natera’s Research team is building tests that can detect many cancers from a single blood draw. We are looking for a Senior or Lead Bioinformatics Scientist to join the team building the technology at the heart of that effort. You will work with large-scale, multi-modal genomic datasets from clinical cohorts and partner closely with molecular biologists and clinical scientists. You will help advance the state-of-the-art and drive new methods from prototype, through scalable implementation, toward clinical validation and, ultimately, to patients. PRIMARY RESPONSIBILITIES: Develop and validate new algorithms to analyze large multimodal epigenomic datasets Drive research analyses through implementation, testing and performance evaluation, including developing new features within existing pipelines Work with sequencing and clinical data from large cohorts, ensuring data integrity and quality control Partner with molecular biologists and clinical scientists to solve challenging, open-ended problems Visualize results and present complex findings to both technical and non-technical audiences Contribute to the team’s standards for code quality and reproducibility QUALIFICATIONS: Ph.D. in Bioinformatics, Computer Science, Biology, or a related field; alternatively a Bachelor’s or Master’s degree with at least 4 years of professional experience Track record developing and validating analysis workflows for high-throughput sequencing data Experience applying and evaluating statistical and ML methods to large datasets Strong quantitative reasoning and data analysis skills, applied effectively to real scientific problems. Software development experience, including proficiency in Python and its scientific computing ecosystem Fluent using Linux command-line tools and cloud computing environments Strong verbal and written communication skills Preferred Experience Working knowledge of DNA methylation and other epigenomic data Experience with cell-free DNA and liquid biopsy samp

POSITION SUMMARY: The Senior Design Transfer Scientist will lead and support the transition of In Vitro Diagnostic (IVD) Next-Generation Sequencing (NGS) assays from R&D to Operations. This role is responsible for planning, executing, and documenting all design transfer activities while ensuring strict compliance with regulatory and quality standards. The ideal candidate will balance hands-on laboratory work, data analysis, and documentation. As a cross-functional collaborator, you will interface with multiple functional groups to drive project deliverables to completion in a dynamic, fast-paced environment. PRIMARY RESPONSIBILITIES: Design Transfer & Validation: Plan and execute process validations (IQ/OQ/PQ), stability studies, and study protocols; perform data analysis and author final reports Test Method Development: Support test method development, characterization, and Test Method Validation (TMV), including the generation of manufacturing specifications Quality & Risk Management: Lead Risk Management activities (including FMEAs) to identify and mitigate product risks; establish and maintain Design History Files (DHF) and Device Master Records (DMR) Sustaining & Change Control: Lead change control activities to evaluate and determine the impact of design changes to on-market products CAPA & Troubleshooting: Investigate product or process deviations, perform root cause analysis, and implement Corrective and Preventive Actions (CAPA) Cross-Functional Collaboration: Partner with Supply Chain to establish raw material and consumable pipelines; present status updates, data, and technical proposals to cross-functional stakeholders EDUCATION & EXPERIENCE: PhD. in Molecular Biology, Cell Biology, Biotechnology, Biochemistry, or a related scientific field with 4+ years of relevant industry experience; OR Master’s degree in the fields above with 7+ years of relevant industry experience; OR Bachelor’s degree in the fields above with 10+ year

LOCATION : This will be a hybrid role (1 day a week) working out of our San Carlos, CA location. POSITION SUMMARY: Natera is a global leader in cell-free DNA testing, supporting oncology, women’s health, and organ health. Our goal in R&D operations data science is to support R&D activities at Natera through data analytics and the development of intelligent tools to optimize workflows and processes. As a Senior Data Analyst on the team, you will play a pivotal role in designing, prototyping, and building out a modern, next-generation AI analytics platform to phase out legacy reporting infrastructure. In this role, you will leverage AI developer tools (e.g., Claude Code, Gemini) to significantly accelerate design, scripting, and platform prototyping. However, speed must be paired with engineering rigor: you must possess deep foundational technical expertise to critically review, audit, validate, and refine all AI-assisted output, ensuring production-grade code quality, data accuracy, and system reliability. PRIMARY RESPONSIBILITIES: Platform Design & Rapid Prototyping: Lead the effort in architecting, iterating, and building out a new R&D analytics platform. Rapidly prototype scalable analytics solutions and modern self-service data tools AI-Accelerated Development & Rigorous Validation: Proactively utilize advanced AI tools (including Claude Code, Gemini, and coding assistants) to accelerate development cycles, automate repetitive coding tasks, and speed up platform prototyping. Thoroughly review, debug, unit-test, and validate all generated code and analytics logic for correctness, security, and efficiency Data Pipeline & SQL Engineering: Extract, clean, transform, and model complex multi-source R&D data. Develop and optimize high-performance custom SQL queries and partner with Data Engineers to enhance database scalability and platform performance Analytics & Insight Generation: Translate operational requirements into act

POSITION SUMMARY The Clinical Lab Supervisor is a leader in Natera’s lab operations whose role is to oversee employees' performance and serve as a liaison between employees and senior management to meet company goals and quality objectives. The supervisor is responsible for daily supervision of lab staff performing duties such as laboratory testing and data review. Duties include but are not limited to coaching, motivating, staffing, evaluating, and training staff. The supervisor works closely with the manager to ensure company and team goals are met while adhering to good manufacturing practices and CLIA/CAP guidelines. The shift timings are from Monday- Friday , 1.00 PM- 9.30 PM PRIMARY RESPONSIBILITIES Responsible for day-to-day staffing/scheduling/setting up sample run schedules. Ensures production work is consistently completed according to department goals. Ensures all case samples are processed and accounted for. Monitors team members to ensure adherence to SOPs and safety procedures Oversees training for new hires: works in conjunction with lead to train new hires. Document nonconformance reports and all corrective actions taken when test systems deviate from the established performance specifications as needed. Escalates protocol deviation to lead/supervisor. Assists manager in initiating and completing CAPAs. Handles employee issues. Collaborates with Manager and/or Human Resources to resolve issues. Ensures alignment with team for reasoning behind instructions/processes and changes Meets regularly with individual team members to discuss goals and progress. Responsible for staff performance reviews. Plans and leads shift meetings Maintains team morale and professionalism of team members, including by acting as role model. Adheres to Departmental Expectations Ensures compliance with all regulatory agency requirements through documentation, audits, and corrective action. Go-to person when manager is not present. May assist lab team in day to day