Senior Strategist; Program Manager

About Tr1X Tr1X is a clinical-stage biotechnology company developing engineered Tr1 cell therapies to restore immune balance in autoimmune and inflammatory diseases. Leveraging the unique biology of Tr1 cells, the company is advancing a pipeline of off-the-shelf allogeneic and in vivo CAR-Tr1 therapies designed to deliver targeted immunoregulation and address diseases driven by immune dysfunction, including transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable, potentially curative therapies for conditions with high unmet need. For more information, visit www.tr1x.bio . Position Summary The Director/Senior Director, Program Management provides strategic leadership and performs hands-on operational activities supporting cell therapy programs in autoimmune indications. This individual aligns cross-functional teams, manages dependencies and risks, and ensures programs deliver against milestones and organizational objectives. The Director/Senior Director partners closely with Clinical Development, Clinical Operations, Regulatory, Technical Operations and R&D, along with external partners to drive execution of complex preclinical and clinical programs from early development through registrational studies. Key Responsibilities Translate program strategy into integrated timelines, milestones, and deliverables, ensuring coordination across all contributing functions. Provide program/project management expertise and support to advance Tr1X's Tr1, CAR-Tr1 and in vivo cell therapy programs. Provide program management of one or more highly complex R&D programs and/or high-profile partnerships. Communicate with project team members, management leadership team, department heads, and key stakeholders including KOLs. Track and monitor key milestones and decision points to drive delivery of project objectives. Develop and refine tools for project governance and program timeline

About Tr1X Tr1X is a clinical-stage biotechnology company developing engineered Tr1 cell therapies to restore immune balance in autoimmune and inflammatory diseases. Leveraging the unique biology of Tr1 cells, the company is advancing a pipeline of off-the-shelf allogeneic and in vivo CAR-Tr1 therapies designed to deliver targeted immunoregulation and address diseases driven by immune dysfunction, including transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable, potentially curative therapies for conditions with high unmet need. For more information, visit www.tr1x.bio. Position Summary The Director, Medical and Regulatory Writing reports to the Vice President, Head of Regulatory Affairs and provides strategic planning, development, review, and delivery of high-quality medical, clinical, and regulatory documentation supporting Tr1X clinical programs. The role is responsible for establishing and executing medical writing strategies across clinical development programs, ensuring the timely preparation of scientifically accurate, regulatory-compliant documentation. The Director drives document quality and operational excellence and collaborates with senior leaders across Clinical Development, Regulatory Affairs, Biostatistics, Clinical Operations, Translational Medicine, CMC/Technical Operations, and other functions. The position plays a critical role in supporting regulatory milestones and submissions throughout the product lifecycle, while ensuring alignment with applicable regulatory requirements, scientific standards, and corporate objectives. Key Responsibilities Partner with Regulatory to develop and implement the medical writing strategy in alignment with corporate objectives, clinical development plans, regulatory strategies, and program goals. Author (writes & edits) high-quality documents across all program areas as needed such as clinical study protocols, protocol ame

Who We Are: LINK is a fast-growing Woman Owned Small Business (WOSB) that leverages human-centered design to support strategy, innovation, communication, change, and branding within the federal government and adjacent industry partners. At LINK, we partner with engineers, futurists, and thought leaders to untangle complexity, discover opportunity, and communicate clearly with visual stories. Let us be your partners in change. Location: We are actively hiring in the San Diego area. About the Opportunity LINK is actively seeking a Senior Design Strategist to join our dynamic team, where we leverage strong partnerships and a robust portfolio of clients across diverse industries. You will be responsible for leading and executing innovative design strategies, collaborating with both internal teams and executive-level clients, and driving impactful visual storytelling to meet client objectives. This is an exciting opportunity for an experienced professional to bring a combination of creative and strategic expertise to elevate LINK’s business growth and deliver high-quality, human-centered design solutions. You will work closely with clients to understand their challenges, develop compelling narratives, and implement design strategies that align with their mission, goals, and brand identity. Ideal candidates will have a proven track record of designing impactful visual experiences, utilizing data-driven insights, and collaborating cross-functionally to deliver exceptional client results. Qualifications Bachelor’s degree in Design, Communication, Sociology, Psychology, Human-Centered Design, or a related field. 10+ years of experience in design strategy, service design, user experience, research, consulting, communications, or a related field. Ability to obtain and maintain a security clearance. Strong expertise in human-centered design, design thinking, systems thinking, facilitation, and strategic storytelling. Well-versed

About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. Own your portfolio and drive strategic growth across global trade. The opportunity: The Sales team at Flexport is critical to our mission, fostering deep, lasting relationships that drive client success and accelerate global trade. As an Account Executive II (Farmer), you operate with independence. You own a portfolio of accounts and are the architect of their success — not just the executor of a plan. Your clients are growing in complexity: multiple trade lanes, operational nuance, and real expansion potential. You know Flexport's product suite well enough to connect client needs to solutions with confidence, and you drive revenue growth within your book without being directed. Senior leadership trusts your judgment on the accounts you own. This is where you move from learning the craft to mastering it. You will: Own the success and retention of a portfolio of Flexport clients, managing relationships independently and proactively — you identify problems before clients raise them. Lead all client communications and strategic engagements, including QBRs/MBRs, without requiring support from senior teammates for routine situations. Identify and execute cross-sell and

About Tr1X Tr1X is a clinical-stage biotechnology company developing engineered Tr1 cell therapies to restore immune balance in autoimmune and inflammatory diseases. Leveraging the unique biology of Tr1 cells, the company is advancing a pipeline of off-the-shelf allogeneic and in vivo CAR-Tr1 therapies designed to deliver targeted immunoregulation and address diseases driven by immune dysfunction, including transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable, potentially curative therapies for conditions with high unmet need. For more information, visit www.tr1x.bio . Position Summary The Senior Director, Quality (SD) reports to the Chief Technical Officer and is responsible for all aspects of the quality organization including support and oversight for all internal and external GxP operations inclusive of clinical quality assurance (CQA). As the leader of the quality function, the SD establishes and maintains a culture of quality across the organization and is responsible for overseeing development, implementation, and continuous improvement of all quality systems to ensure that all products, processes, and operations comply with applicable regulatory requirements. The SD is ultimately responsible and accountable for critical decisions that directly impact product integrity, patient safety, regulatory compliance, and business continuing. The SD works with both internal and external stakeholders to manage timelines, meet internal deliverables and develop a best-in-class quality organization. This position develops, leads, and coaches the teams responsible for quality systems, quality control, document control, quality assurance, clinical quality, and compliance. The SD responsibilities include implementation and continuous improvement of policies, procedures and standards necessary to ensure compliance with applicable GxPs. Additional responsibilities include team building, ca

About Tr1X Tr1X is a clinical-stage biotechnology company developing engineered Tr1 cell therapies to restore immune balance in autoimmune and inflammatory diseases. Leveraging the unique biology of Tr1 cells, the company is advancing a pipeline of off-the-shelf allogeneic and in vivo CAR-Tr1 therapies designed to deliver targeted immunoregulation and address diseases driven by immune dysfunction, including transplant-related complications. Founded by pioneers in the discovery of Tr1 cells, Tr1X, Inc. is focused on developing durable, potentially curative therapies for conditions with high unmet need. For more information, visit www.tr1x.bio. Position Summary The Senior Scientist, In vivo Immunology – Targeted LNP Delivery is an experienced, hands-on immunologist who leads the biological design and evaluation of targeted lipid nanoparticle (tLNP) formulations supporting the Tr1X in vivo chimeric antigen receptor (CAR)-Treg platform. Reporting to the Executive Director of Biology, this individual plays a central R&D role in advancing tLNP delivery systems — defining the immunological targeting rationale and driving in vitro and in vivo proof-of-concept studies — to enable precise, immune cell-specific delivery of nucleic acid payloads. This is a high-impact, science-driven role focused on the discovery and development of Tr1X’s next-generation tLNP delivery platform. The Senior Scientist brings deep expertise in immunology, particularly T cell and Treg biology, hands-on experience applying tLNPs in immune cells, strong experimental rigor across in vitro and in vivo studies, and the ability to thrive in a fast-paced startup environment. Key Responsibilities Partner with formulation and chemistry colleagues on the design and optimization of targeted lipid nanoparticle (tLNP) formulations for mRNA payloads, owning the immunological targeting criteria and biological evaluation. Design and execute in vitro and in vivo studies, including humanized models,