Staff Scientist R&D

Natera is seeking a Staff Scientist to join our Early Research Team. The primary focus of this role is to independently lead the research and development of novel next-generation sequencing (NGS) technologies. In this role, you will lead projects from ideation to prototype, specifically designing and optimizing high-complexity NGS methods to advance our oncology diagnostic portfolio. Success in this role requires a deep technical foundation in molecular biology and NGS plus a proven track record of industrial R&D leadership. Primary Responsibilities: Lead and manage the development of innovative NGS-based diagnostic assays from feasibility through optimization. Define project goals and plans with input from stakeholders and manage multiple project streams in parallel. Independently design and execute complex laboratory experiments; analyze and interpret results to guide research direction. Coordinate cross-functional efforts to meet milestones and collaborate closely with bioinformatics, statistics, and data science teams to ensure robust experimental design and data analysis. Mentor and guide junior scientists while promoting scientific rigor and best practices. Author high-quality protocols, technical reports, and study documentation. Communicate progress regularly to stakeholders, including departmental meetings and senior leadership. Contribute to risk management, strategy development, and continuous improvement of scientific workflows. Qualifications: Ph.D. in molecular biology, genomics, or a closely related field. Minimum 8 years of relevant industry experience, or 2+ years postdoctoral research with 6+ years in industry. Proven experience in designing and advancing NGS-based diagnostics, preferably in the field of oncology. Required Expertise: A strong technical foundation in molecular biology or chemistry. Deep mechanistic knowledge of NGS library preparation chemistry. Demonstrated ability to independently design and execute complex experiments (solid

Natera’s Research team is building tests that can detect many cancers from a single blood draw. We are looking for a Staff Machine Learning and Bioinformatics Scientist to help design the models at the heart of that effort. You’ll work with large-scale, multi-modal genomic datasets from clinical cohorts and partner closely with molecular biologists and clinical scientists. Your research will advance the state-of-the-art and you will drive new methods from prototype, through scalable implementation, toward clinical validation and, ultimately, to patients. PRIMARY RESPONSIBILITIES: Lead the development of novel statistical and machine learning methods for cancer signal detection on multi-modal genomic data Build interpretable, well-calibrated models, setting the standard for uncertainty estimation and reproducibility across the group Prototype, test and productionize ML models using scalable infrastructure Own key technical deliverables within larger projects and help shape the team’s research roadmap Collaborate closely with molecular biologists and clinical experts on design and analysis of experiments and validation studies Keep raising the bar through code and design reviews across projects Translate complex results into clear stories for technical and non-technical audiences Mentor junior scientists and champion a culture of curiosity, collaboration, and scientific excellence QUALIFICATIONS: PhD in Computer Science, Mathematics, Bioinformatics, or a related quantitative field with 6-12 years of experience post-PhD Hands-on experience developing novel statistical / ML analysis methods applied to complex biological data Proven track record of innovation and technical leadership in complex method development projects Expertise in deep learning and multimodal foundation models Proficient in Python and its scientific computing ecosystem Scientific rigor throughout the R&D process, with eagerness to teach and learn new computational methods and biology Excellent co

Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Reddit’s Ads Data Science team is looking for a highly experienced Staff Data Scientist to advance the intelligence powering the advertiser experience on Reddit. In this role, you'll take deep ownership of a high-impact problem space within advertising, specializing in measurement, identity, and signal quality. This is a high-impact, high-autonomy role where you'll influence strategic direction, set a high technical bar, and drive cross-functional initiatives across one or more critical focus areas in the Ads organization. Responsibilities: Design the Future of Ads Identity: Develop/employ probabilistic models for identity resolution. Design the methodology that links on-platform and off-platform actions to maximize addressability while honoring privacy. Advance Lift Methodologies & Experimentation: Own the statistical rigor behind Reddit’s Brand and Conversion Lift products. Innovate experimental design and develop infrastructure that supports large-scale, high-velocity, low-bias testing for advertisers. Maximize Signal for Predictive Performance: Define the strategy for new signal sources. You will mathematically quantify the value of these signals and work with modeling teams to incorporate them into predictive models, directly improving bidding efficiency and ROAS. Define Ground Truth & Evaluation Frameworks: Solve the industry-wide challenge of validating identity and measurement. Design the objective functions and truth sets used to train our models and measure the incremental impact of our identity graph.

Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Location: US remote-friendly Reddit has a flexible first workforce. At Reddit we continue to grow our teams with the best talent. We're completely remote friendly and will continue to be. Advertising is Reddit’s primary revenue driver and we have an ambitious goal to turn it into a massive business. Although several large digital ad platforms already exist, advertisers are being increasingly drawn to Reddit because of our passionate communities. We believe our community-centric platform has created the opportunity for Reddit to build a highly differentiated ads business. About the Ads Data Science Team: The Ads Data Science team at Reddit leverages data to maximize advertiser value on Reddit through robust data foundations, metrics, and strategic insights generated through experimentation and cutting-edge DS methods. We work on a wide range of challenging problems in the areas of ads and platform measurement, campaign and creative management, advertiser growth and retention, monetization, and the intersection of brand and community engagement. We are a highly collaborative team of passionate data scientists and engineers who are constantly pushing the boundaries of what's possible with machine learning and statistical modeling. About the Role: Reddit’s Ads Data Science team is looking for a highly experienced Staff Data Scientist to advance the intelligence powering the advertiser experience on Reddit. In this role, you'll take deep ownership of a high-impact problem space within advertising, specializing in measu

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: You will join the Guest and Host Data Science organization, which powers products and data-driven decisions over Airbnb’s marketplace of Guest and Hosts. You will join a collaborative team of data scientists, analysts, engineers, product managers and designers who build, launch and iterate on our product roadmap to drive growth and deeper sophistication through experimentation, modeling, foundational tools and insights. Our work is core to ensuring that Airbnb’s strategy roadmap stays highly relevant for our users while supporting the long-term health of our marketplace. We work directly with decision makers in engineering and product to develop data-driven frameworks, technical solutions, evaluate product changes and guide the company through rigorous measurement and modeling. The Difference You Will Make: Under this general application, you will be considered for applications over several tracks. Growth Product Data Science Partner directly on growth initiatives to build, ship, measure incrementality of bookings/attach rate/revenue, and optimize 0-to-1 customer-facing features Thought partnership with Product to define strategy, sequence iteration, scale impact via science frameworks and as the go-to tech lead around data, experimentation, and domain understanding Build observational causal inference models to deeply understand guest intent, identify underlying mechanisms, and build data products to measure impact, and inform feature objectives and tradeoffs Champion AI-enabled Product Understanding, to scale data-driven frameworks, robust measurement, and compelling storyte

The Dashboards product is Datadog's unified single-pane-of-glass for metrics, logs, and traces—a comprehensive treasure trove of observability data. We are transforming Dashboards into an AI-native control surface and the central hub where every team moves seamlessly from question to insight to action – providing a guided experience that feels like having an expert SRE at your side and ensuring the entry point is never an empty canvas. We're hiring a Staff Applied Scientist to define and guarantee the quality of this AI system at scale. "Good" isn't one number — it spans answer quality, tool-selection accuracy (critical given the growing catalog of data sources and visualizations), retrieval relevance, latency, token cost, and end-to-end agent success. The space is full of open questions. How do you evaluate an agent end-to-end when the trajectory is non-deterministic? How do you score tool selection when a user’s query can result in the agent making decisions against dozens of visualizations and data sources – both of which are growing month over month? How do you build a measurement system that catches regressions across all widget types and data sources (e.g., enforcing correct grouping, sorting, and time overrides), and is easy to use and extend by dozens of teams? If those are the problems you want to spend your time on, come build this with us. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the evaluation strategy for Dashboards, as well as sister teams within our organization. Define the metrics — offline and online, quality and cost, single-turn and multi-turn — that the team and the broader organization optimize against. Build the eval datasets, golden traces, and regression harnesses that catch quality changes before they hit customers, an