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City Business Lead Jobs

1,823 active opportunities · Updated for October 2026

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Explore current city business lead jobs. Use filters to narrow by work mode, employment type, experience and date posted.

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Biohub
📍 Redwood City• Full-time• Hybrid• $214K – $268K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity The Security Engineering and Infrastructure team brings modern security engineering practices to the Biohub network to make sure our systems are secure while we accelerate Biomedical research. We are uniquely positioned to design, build, and scale software systems to help scientists better address the myriad challenges they face. This team works on building shared tools and platforms to be used across

pythonci/cdrest
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Biohub
📍 Redwood City• Full-time• Hybrid• $241K – $301K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health—advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute acro

restaigo
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B
Biohub
📍 Redwood City• Full-time• Hybrid• $214K – $294.8K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This role is part of the Data team, which focuses on owning the strategy, sourcing and implementation for data supporting AI research and development. Our goal is to maximize the speed, agility, and capability of biological AI research by connecting public data resources and Biohub's experimental platforms to AI systems. The data that trains biological frontier models comes in dozens of modalities—sequences, images, sp

pythonrestmachine learning
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Biohub
📍 Redwood City• Full-time• From $106K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work here . Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity We are looking for a self-motivated individual with a scientific background to join the Lab Management team. This role will report to the Senior Lab Manager and support group leaders, platform leaders, and scientists within the Biohub to carry out their role(s). The Lab Management team is responsible for the day-to-day operations and implementation of processes to ensure smooth operation of the laborat

restaigo
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Biohub
📍 Redwood City• Full-time• $71K – $89K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This is an opportunity in the AI Research Wet Lab team to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health—advancing frontier AI research, connecting rich biological data to AI systems, and translating models and data i

pythonrestai
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B
Biohub
📍 Redwood City• Full-time• Hybrid• $241K – $331K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The AI Cluster Production Engineering team is part of the AI Compute Platform organization at Biohub, a non-profit research lab committed to open science and open-source AI. We own the design, operation, and reliability of large-scale multi-GPU AI clusters that power frontier AI biology research: protein language models, genomic foundation models, and scientific reasoning systems built to be shared, not monetized. Our clusters run Slurm on Kubernetes infrastructure and support everything from day-to-day AI researcher workflows to multi-node hero training runs at thousands of GPUs. The team works at the intersection of AI tooling, distributed systems, HPC, and frontier AI, debugging deep AI infrastructure problems and building AI systems critical to the entire AI organization. The Opportunity CZ Biohub's mission is to cure or prevent all human disease. Achieving that requires training frontier-scale AI biology models, and that demands reliable, high-performance compute infrastructure. This is production engineering work at a frontier AI lab, with the twist that the mission is biology and the science is open. You'll keep GPU clusters running at high utilization, debug the toughest distributed systems failures, and build the operational foundations for scaling to multi-thousand GPU hero runs. The technical problems are genuinely hard (e.g., multi-node distributed training, InfiniBand fabrics, large-scale storage, Slurm at scale) inside an organization where the work is aimed at helping peop

pythonkubernetesgit
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B
Biohub
📍 Redwood City• Full-time• Hybrid• $214K – $375K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Engineer, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at th

restaigo
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B
Biohub
📍 Redwood City• Full-time• Hybrid• $214K – $375K/yr
1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Scientist, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at t

restaigo
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