Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X . About This Role Axsome Therapeutics is currently searching for a Regional Business Director (RBD) to lead commercial activities for an assigned geography, establish a team of Account Managers, execute marketing strategies, and ensure a successful launch. The RBD will be primarily responsible for the supervision and leadership of an industry shaping, uniquely structured salesforce leveraging the use of a highly sophisticated digital infrastructure. All sales representatives will be aligned to geographical boundaries. The RBD is responsible for sales performance at a Region level and is expected to be a product champion and exhibit the business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace. This is a cross-functional front-line leader role that will ensure successful promotion of AUVELITY for major depressive disorder in adults and potential future indications. The position is field-based and will require travel as needed to
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About Us At Cloudflare, we are on a mission to help build a better Internet. Today the company runs one of the world’s largest networks that powers millions of websites and other Internet properties for customers ranging from individual bloggers to SMBs to Fortune 500 companies. Cloudflare protects and accelerates any Internet application online without adding hardware, installing software, or changing a line of code. Internet properties powered by Cloudflare all have web traffic routed through its intelligent global network, which gets smarter with every request. As a result, they see significant improvement in performance and a decrease in spam and other attacks. Cloudflare was named to Entrepreneur Magazine’s Top Company Cultures list and ranked among the World’s Most Innovative Companies by Fast Company. At Cloudflare, we’re not looking for people who wait for a polished roadmap; we’re looking for the builders who see the cracks in the Internet that everyone else has simply learned to live with. We value candidates who have the instinct to spot a "normalized" problem and the AI-native curiosity to create a solution using the latest tools. Our culture is built on iteration, leveraging AI to ship faster today to make it better tomorrow, while ensuring that every improvement, no matter how small, is shared across the team to lift everyone up. If you’re the type of person who values curiosity over bureaucracy, and that AI is a partner in solving tough problems to keep the Internet moving forward, you’ll fit right in. Available Locations Austin, US New York, US San Francisco, US Responsibilities Lead and Mentor: Manage a high-performing team of kernel and systems engineers, fostering a culture of "collaboration-first" and continuous knowledge sharing both internally and with the global open-source community. Own the OS Lifecycle: Oversee the end-to-end delivery of the Linux Kernel and core OS components. Your goal is a fully automated continuous delivery pipeli
About the Team At Trendyol Tech, our mission is to create a positive impact in our ecosystem by enabling commerce through technology. We solve complex problems with data, creativity, and agility — always driven by real outcomes. With a culture built on learning, collaboration, and ownership, we grow together while building what’s next. About the Role As a leading and fast-growing e-commerce company, our physical infrastructure is the backbone of our massive logistics and digital ecosystem. We operate high-capacity, multi-site data center environments supporting our continuous digital operations. In addition, our physical footprint spans a highly distributed network of nationwide logistics centers, fulfillment hubs, and corporate offices. We are seeking a highly resilient, strategically minded, and hands-on Infrastructure & Field Operations Manager to lead our Field Operations Team. In this role, you will oversee all physical infrastructure deployments, structured cabling, rack installations, hardware maintenance, and field operations across all our data centers, supply chain networks, and offices.
About the Team OpenAI's Industrial Compute organization builds and operates the infrastructure required to train and serve frontier AI models. The Capacity Planning team connects rapidly changing research and product demand with the compute, networking, storage, power, data center, hardware, and operational resources required to make that demand executable. About the Role We are seeking a Technical Program Manager to build and lead capacity planning across OpenAI's large-scale AI infrastructure. You will translate uncertain workload demand into clear infrastructure requirements, allocation decisions, supply commitments, activation priorities, and long-range capacity strategies. This role sits at the intersection of research, engineering, infrastructure, finance, sourcing, deployment, and operations. You will create the planning models, operating cadences, governance mechanisms, and source-of-truth systems that allow teams to understand what capacity is required, what is available, what is at risk, and what decisions must be made. This is not a finance-only forecasting or reporting role. Success requires technical fluency across the infrastructure stack, strong analytical judgment, and the ability to move consequential decisions forward when requirements, timelines, and supply conditions change quickly. Key Responsibilities Own capacity-planning processes across near-term workload allocation, quarterly execution, and longer-range infrastructure horizons. Translate research, training, inference, and product demand into compute, accelerator, cluster, networking, storage, rack, power, and site requirements. Develop scenarios that make assumptions, confidence levels, constraints, sensitivities, and decision points explicit. Reconcile requested demand against contracted, delivered, installed, activated, and workload-usable capacity. Partner with research and engineering teams to understand workload priorities, technical dependencies, utilization patterns, and changing req
About the Team OpenAI's data and storage infrastructure spans data platforms, online databases, and file/object storage. These systems underpin data ingestion and processing, durable persistence, indexing and retrieval, and product file experiences. As frontier models and agents evolve how they use memory, history and snapshots, the underlying architecture increasingly shapes the capabilities products can deliver—and their latency, reliability, cost and efficiency. About the Role We are looking for a technically deep TPM to independently define and lead multiple programs across data platforms, online databases and storage infrastructure. You will connect model, product and data-consumer requirements to architecture, and work with the relevant engineering teams to take new capabilities through production adoption and repeatable expansion. The design scope is exabyte-scale storage and infrastructure spanning multiple millions of CPU cores. The challenge is not simply forecasting more resources: it is making complete, workload-ready capacity repeatable, with a clear path from product requirements through architecture, deployment and validation. A data pipeline, database query, file operation or execution snapshot can affect whether a product or agent succeeds; you will connect those outcomes to the systems underneath. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Translate model, product and data-platform needs into precise access patterns, consistency, durability, freshness, availability and scalability requirements. Connect memory, history, retrieval and resumable work to capability and end-to-end latency. Partner with engineering to transform data and storage architecture into repeatable scale units: standardized provisioning, placement, routing, data movement and readiness checks that bring storage, compute and networking online together.
About the Team OpenAI's Industrial Compute organization is building and operating the infrastructure foundation for the next generation of AI. Infrastructure Operations works across facilities, hardware, network operations, incident management, data center engineering, delivery teams, and external partners to bring capacity online safely, understand its operational state, and improve it over time. As OpenAI's data center portfolio grows across first-party and partner-delivered capacity, the organization needs clear goals, trusted data, repeatable processes, and systems that make ownership, risk, readiness, and performance visible. This role will help build the operating mechanisms that allow Infrastructure Operations to scale with rigor. About the Role We are seeking a Technical Program Manager to own the systems, data, reporting, governance, and program-management backbone for Infrastructure Operations. Reporting to the Delivery & Operations Lead, you will translate strategy into executable goals and operating cadences, turn operational needs into software and data solutions, and create the mechanisms that keep a rapidly evolving organization aligned and accountable. This role will also own the current 1P+3P delivery-tracking layer within Operations: milestones, delivery timelines, quantity forecasts, risks, decisions, and executive reporting. You will partner closely with 1P Delivery Program Management, Compute TPMs, Data Center Engineering, construction, commissioning, and operations leaders to ensure that delivery information becomes complete, usable input for readiness, handover, and ongoing operations. You will own program health and the operating system around it: the goals, data definitions, workflows, reporting, decision paths, and follow-through that help functional DRIs execute. The ideal candidate is comfortable in ambiguity, technically fluent enough to implement real systems, and relentless about converting scattered information into durable mechan
About the Team OpenAI's Industrial Compute organization is building the world's most advanced AI infrastructure ecosystem. In partnership with leading cloud providers, hardware manufacturers, utilities, construction partners, and internal engineering organizations, we are delivering hyperscale AI campuses that power the next generation of frontier AI models. Infrastructure Delivery Operations sits at the center of this effort. Our team develops the operating model that connects infrastructure strategy, supply planning, manufacturing operations, and delivery into a single, integrated system that enables OpenAI to deploy AI infrastructure predictably at scale. We partner across Hardware Engineering, Network Engineering, Capacity Delivery, Hardware Operations, Security, Finance, Strategic Sourcing, and external infrastructure partners to create a single, integrated view of program health. Through governance, operational analytics, executive reporting, and scalable operating mechanisms, we enable leaders to proactively manage risk, optimize capacity, and deliver infrastructure predictably at Industrial Compute speed. About the Role We are seeking a Technical Program Manager, Infrastructure Delivery Operations to drive integrated strategy and delivery across OpenAI's rapidly expanding AI infrastructure portfolio. This role sits at the intersection of infrastructure strategy, New Product Introduction (NPI), supply planning, manufacturing operations, and infrastructure delivery. You will lead highly cross-functional programs spanning engineering, supply planning, manufacturing, logistics, construction, commissioning, and operations, ensuring technical and operational dependencies remain synchronized from planning through production readiness. Beyond driving program execution, you will leverage operational insights to improve capacity planning, infrastructure strategy, and deployment readiness. You will also help operationalize new technologies and suppliers by partnering w
About the Team OpenAI’s Industrial Compute organization is building the infrastructure required to support the next generation of frontier AI systems. Through a combination of strategic partnerships and self-built data center campuses, we are scaling the physical infrastructure needed to deliver compute at unprecedented scale. The Commissioning organization is responsible for ensuring this infrastructure is safely tested, validated, integrated, and transitioned into reliable operations. As the portfolio grows, the team is building common standards, processes, tools, and reporting systems that allow commissioning programs to operate consistently across projects while giving teams and leadership clear visibility into readiness, risk, and execution. About the Role We are seeking a Commissioning Program Manager to build and scale the operating systems behind OpenAI’s infrastructure commissioning programs. You will own the development and continuous improvement of commissioning standards, processes, tools, dashboards, and KPIs across the infrastructure portfolio. You will work closely with commissioning and construction teams to translate field execution needs into practical playbooks, workflows, templates, metrics, and reporting mechanisms that teams can use from construction readiness through testing and turnover. This role sits at the intersection of infrastructure delivery, program management, process design, and data. The ideal candidate understands how complex construction projects operate and can turn fragmented workflows and project data into repeatable systems that improve execution without creating unnecessary administrative burden. Key Responsibilities Develop and maintain commissioning program standards, playbooks, process maps, templates, checklists, stage gates, and acceptance criteria across infrastructure projects. Establish consistent workflows for commissioning planning, construction readiness, QA/QC, issue management, document control, testing evidence
About the Team OpenAI's Industrial Compute organization is building the world's most advanced AI infrastructure ecosystem. In partnership with leading cloud providers, hardware manufacturers, utilities, construction partners, and internal engineering organizations, we are delivering hyperscale AI campuses that power the next generation of frontier AI models. Infrastructure Delivery Operations sits at the center of this effort. The team ensures that large, highly complex infrastructure programs execute predictably across planning, design, construction, hardware deployment, commissioning, and operational handoff. We partner across Hardware Engineering, Network Engineering, Capacity Delivery, Hardware Operations, Security, Finance, Supply Chain, and our external infrastructure partners to keep programs aligned, risks visible, and execution moving at Industrial Compute speed. About the Role We are seeking a Technical Program Manager, Infrastructure Delivery Operations to drive execution across large-scale AI infrastructure deployments. This role is responsible for orchestrating cross-functional delivery programs spanning multiple organizations, ensuring dependencies remain synchronized from early planning through production readiness. You will develop operational mechanisms that allow Industrial Compute to scale infrastructure delivery across multiple campuses simultaneously. Rather than owning any individual engineering discipline, you will own program health—bringing together engineering, construction, operations, supply chain, and partner organizations into a single coordinated execution model. Success in this role requires exceptional program management, executive communication, systems thinking, and operational rigor. You should be comfortable operating amid ambiguity while bringing structure to highly technical, multi-year infrastructure programs. Candidates should have experience leading complex infrastructure, cloud, data center, semiconductor, networking, manuf
About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the Role As a Supply Chain Program Manager, you will own material readiness and supply chain execution for critical hardware programs spanning custom silicon, systems, memory, storage, networking, and rack infrastructure. You will work cross-functionally with Engineering, Strategic Sourcing, Manufacturing Operations, Finance, Planning, Quality, and external suppliers to develop and execute scalable supply strategies that support aggressive product development and deployment timelines. This role requires deep understanding of hardware supply chains, material planning, NPI execution, supplier management, and operational scaling in constrained and rapidly evolving environments. In this role you will: Material Readiness & Supply Planning - Own end-to-end material readiness across NPI and production phases, including building the necessary framework and processes for enablement. Drive supply planning and execution for long lead-time and constrained commodities including ASICs, HBM, DDR, SSDs, networking, optics, power, thermal, and mechanicals. Build and manage material readiness plans aligned to proto/pre-EVT, EVT, DVT, PVT, and mass production schedules. Monitor supply health, lead times, inventory positions, allocation risk, and capacity constraints. Drive shortage management, allocation mitigation, and recovery planning. Coordinate supply commits, forecast alignment, and supply continuity planning with suppliers and manufacturing partners. Cross-Functional Program Ma
About the Team OpenAI, in close collaboration with our capital partners, is building the world’s most advanced AI compute infrastructure ecosystem. The InfraDev team is central to this mission, setting the strategy and executing the roadmap to scale our supercomputing footprint globally. From site planning to system integration, this team operates at the intersection of commercial, technical, and operational excellence, partnering with leaders across OpenAI and the industry. About the Role We are seeking a Strategic Sourcing Manager who is ready to take on global-scale challenges in AI compute supply and manufacturing — an opportunity to shape the future of supercomputing. As part of the Infrastructure Strategy & Delivery organization supporting Industrial Compute, OpenAI’s next-generation supercomputing platform, you will lead sourcing and strategic supplier engagements for compute infrastructure at hyperscale. This role will drive commercial strategy and supplier accountability across server platforms, accelerators, rack systems, and associated thermal & power delivery components. This is not traditional procurement — it is foundational work enabling OpenAI to deploy compute faster and more efficiently than anyone in the world, while building deeply-integrated partnerships with the global compute supply chain. Key Responsibilities Develop and execute sourcing strategies for the next generation of AI compute infrastructure in partnership with engineering and program leadership. Stay at the leading edge of industry and supply-chain trends to inform category strategy and long-range planning. Initiate, negotiate, and manage commercial agreements across OEM/ODM/JDMs for accelerators, GPUs/CPUs, server platforms, rack systems, liquid-cooling components, PSUs, and supporting mechanical/electrical subsystems. Secure capacity and optionality across a rapidly scaling compute supply chain while mitigating risk and ensuring manufacturing readiness. Partner cross-funct
About the Team OpenAI is building the infrastructure foundation for the next generation of AI. The Data Center Engineering team defines the strategy, reference architectures, technical requirements, and delivery standards for the large-scale data centers that support OpenAI research, products, and infrastructure partners. As a Data Center Infrastructure Engineering Program Manager, you will help turn complex infrastructure strategy into executable programs across electrical, mechanical, controls, network, hardware, construction, commissioning, deployment, and operations workstreams. You will partner with research, hardware engineering, data center engineering, site development, supply chain, security, EHS, finance, legal, operations, and external delivery partners to bring OpenAI's infrastructure vision to life. About the Role We are looking for an Engineering Program Manager (EPM) to lead assigned infrastructure programs focused on production and non-production network integration, controls coordination, and the design and deployment of data hall or whitespace facilities. The EPM will support functional Directly Responsible Individuals (DRIs) across network, controls, structural, electrical, and mechanical disciplines. Key responsibilities include coordinating assigned workstreams and program controls, maintaining risks and interfaces, and supporting readiness within the network and data hall deployment track. The ideal candidate thrives on bringing structure to complex environments characterized by ambiguous technical requirements, large partner ecosystems, tight deadlines, and high operational stakes. This individual must be adept at keeping teams aligned on decisions, risks, dependencies, schedules, and readiness criteria, and escalating gaps or decision points when needed. Candidates should have a proven track record of managing technically challenging engineering programs across major lifecycle phases, including design, validation, procurement, construction, c
About the Team OpenAI's Industrial Compute organization is building the world's most advanced AI infrastructure ecosystem. Working alongside leading cloud providers, engineering firms, construction partners, utilities, and equipment manufacturers, we are delivering hyperscale AI campuses that enable the next generation of frontier AI models. The Strategic Sourcing team develops and executes the commercial strategies that ensure our infrastructure programs have reliable access to the equipment, materials, and strategic partners needed to deliver at unprecedented scale. We partner closely with Infrastructure Delivery, Capacity Planning, Design Engineering, Hardware Operations, Finance, Legal, and our external suppliers to build a resilient global supply network capable of supporting Industrial Compute's long-term growth. As we continue expanding globally, strategic sourcing becomes a critical competitive advantage, ensuring our infrastructure programs remain cost-effective, resilient, and capable of executing against aggressive deployment timelines. About the Role We are seeking a Strategic Sourcing Manager, Data Center Infrastructure: Owner Furnished Equipment to lead sourcing strategy for the critical infrastructure systems that power Industrial Compute campuses. This role will develop commercial strategies, negotiate strategic supplier agreements, and manage relationships across engineering, construction, manufacturing, and infrastructure partners responsible for delivering mission-critical facilities. You will work closely with Infrastructure Delivery, Capacity Planning, Engineering, Finance, Construction, and external suppliers to ensure Industrial Compute has the capacity, supplier relationships, and commercial frameworks required to support rapid global expansion. The ideal candidate has experience sourcing major infrastructure systems for hyperscale data centers, mission-critical facilities, industrial construction, semiconductor manufacturing, energy infrastr
About the Team The Industrial Compute team is responsible for building the physical infrastructure that powers OpenAI’s largest-scale AI systems. We design, deploy, and operate next-generation compute infrastructure across a rapidly expanding global footprint, combining OpenAI-owned infrastructure with strategic cloud and infrastructure partners to support frontier AI workloads. As our infrastructure footprint grows, operational excellence across third-party providers becomes increasingly critical. Our team ensures external infrastructure partners consistently deliver the reliability, performance, and operational maturity required to support OpenAI’s rapidly expanding compute environment. About the Role We are seeking a Hardware Technical Program Manager, Infrastructure Partner Operations to lead operational delivery across OpenAI’s third-party infrastructure partners, including major cloud service providers and strategic compute vendors. In this role, you will serve as the primary operational program manager for external infrastructure partners, driving accountability for service delivery, operational readiness, incident management, performance reporting, and continuous operational improvement. You will work closely with partner engineering and operations teams while coordinating internally across Hardware Engineering, Infrastructure Operations, Capacity Planning, Networking, Supply Chain, Deployment, Reliability Engineering, and executive leadership. Success in this role requires someone who understands how hyperscale infrastructure organizations operate, can establish strong operational governance with external partners, and is comfortable driving complex technical programs without direct ownership of the underlying infrastructure. Key Responsibilities Own operational engagement with third-party infrastructure providers, ensuring consistent execution against operational commitments, service-level agreements (SLAs), and performance expectations. Develop operationa
About the Team OpenAI's Industrial Compute organization is building the world's most advanced AI infrastructure ecosystem. Working alongside leading cloud providers, engineering firms, construction partners, utilities, and equipment manufacturers, we are delivering hyperscale AI campuses that enable the next generation of frontier AI models. The Strategic Sourcing team develops and executes the commercial strategies that ensure our infrastructure programs have reliable access to the equipment, materials, and strategic partners needed to deliver at unprecedented scale. We partner closely with Infrastructure Delivery, Capacity Planning, Design Engineering, Hardware Operations, Finance, Legal, and our external suppliers to build a resilient global supply network capable of supporting Industrial Compute's long-term growth. As we continue expanding globally, strategic sourcing becomes a critical competitive advantage, ensuring our infrastructure programs remain cost-effective, resilient, and capable of executing against aggressive deployment timelines. About the Role We are seeking a Strategic Sourcing Manager, Data Center Infrastructure to lead sourcing strategy for the critical infrastructure systems that power Industrial Compute campuses. This role will develop commercial strategies, negotiate strategic supplier agreements, and manage relationships across engineering, construction, manufacturing, and infrastructure partners responsible for delivering mission-critical facilities. You will work closely with Infrastructure Delivery, Capacity Planning, Engineering, Finance, Construction, and external suppliers to ensure Industrial Compute has the capacity, supplier relationships, and commercial frameworks required to support rapid global expansion. The ideal candidate has experience sourcing major infrastructure systems for hyperscale data centers, mission-critical facilities, industrial construction, semiconductor manufacturing, energy infrastructure, or similarly comple
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