Lab Manager Jobs

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution. The Opportunity The Biohub Chicago is seeking an exceptional Computational Biologist, Spatiotemporal Multi-Omics to join our growing team. We are looking for a creative and collaborative bioinformatics researcher who is excited to build the analytical foundation for our spatiotemporal multi-omics technology platform. What You'll Do Develop data analysis workflows for spatiotemporal and multi-omics datasets. Build visualization tools that enable exploration and interpretation of complex biological data across space and time. Integrate proteo

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our immune cell reprogramming team integrates foundational research on immunology and disease biology with AI-modeling to develop engineered cells that harness our own immune system to detect and treat early signs of age-related diseases, like cancer, Alzheimer’s, and Parkinson’s. These technologies will enable precise, context-dependent therapeutic responses only when and where it is needed. You can learn more about our work here . Our work brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity The newly established Laboratory of Synthetic Spatial Omics at CZ Biohub NY (https://takeilab.org/) advances our understanding of engineered immune cell function within their native microenvironment to design better cell therapeutic approaches. Toward this goal, we develop and integrate state-of-the-art immune cell engineering, imaging-based and sequencing-based multi-omics, and machine learning/AI frameworks. We bring t

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our AI research team sits at the heart of our mission to unlock new dimensions of biological understanding. You will leverage state-of-the-art AI to accelerate discovery and drive transformative insights in biology—developing novel AI models purpose-built for biological research, engineering robust systems that enable breakthrough science at unprecedented scale, and translating these advances into practical tools that empower researchers worldwide. Our approach is comprehensive and integrated, bringing together world-class AI model development, exceptional engineering talent, high-quality biological data, powerful computing infrastructure, and strategic partnerships. Success requires excellence across five interconnected pillars: training frontier AI models specifically for biology; building engineering systems that maximize research velocity and efficiency; executing a sophisticated data strategy that fuels AI development; operating a world-class AI compute platform; and creating impactful products that transform AI capabilities into accessible scientific tools. The Opportunity This is an opportunity to shape the future of biological research by pushing the boundaries of what AI can achieve in science. You’ll work alongside leading experts in AI and biology, with the resources and mandate to tackle some of the most important questions in human health—advancing frontier AI research, accelerating engineering velocity, connecting rich biological data to AI systems, enabling reliable compute acro

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The AI Cluster Production Engineering team is part of the AI Compute Platform organization at Biohub, a non-profit research lab committed to open science and open-source AI. We own the design, operation, and reliability of large-scale multi-GPU AI clusters that power frontier AI biology research: protein language models, genomic foundation models, and scientific reasoning systems built to be shared, not monetized. Our clusters run Slurm on Kubernetes infrastructure and support everything from day-to-day AI researcher workflows to multi-node hero training runs at thousands of GPUs. The team works at the intersection of AI tooling, distributed systems, HPC, and frontier AI, debugging deep AI infrastructure problems and building AI systems critical to the entire AI organization. The Opportunity CZ Biohub's mission is to cure or prevent all human disease. Achieving that requires training frontier-scale AI biology models, and that demands reliable, high-performance compute infrastructure. This is production engineering work at a frontier AI lab, with the twist that the mission is biology and the science is open. You'll keep GPU clusters running at high utilization, debug the toughest distributed systems failures, and build the operational foundations for scaling to multi-thousand GPU hero runs. The technical problems are genuinely hard (e.g., multi-node distributed training, InfiniBand fabrics, large-scale storage, Slurm at scale) inside an organization where the work is aimed at helping peop

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Engineer, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at th

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Our decoding inflammation team builds tools to enable precise molecular-level measurements of inflammation within human tissues in real time, and develop proactive, early interventions that can be deployed when inflammation — which underlies the most significant causes of death worldwide — first flares in the body. You can learn more about our work here . Our team collaborates with three powerhouse universities - Northwestern University, the University of Chicago, and the University of Illinois Urbana-Champaign - to develop first-in-class technologies and make breakthroughs. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity The Chan Zuckerberg Biohub Chicago is seeking outstanding early-career scientists to join and participate in the launch of the Proteoform Spatial Biology Group by continuing their training as a Postdoctoral Fellow in Multimodal Modeling. The Proteoform Spatial Biology Group aims to uncover the spatiotemporal regulation of proteins and their unique molecular forms, proteoforms, in inflammation and autoimmunity. For this position, the ideal candidate is expect

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Scientist, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at t

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Engineer, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at th

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. Biohub operates one of the largest AI compute clusters dedicated to biology, spanning three frontier research institutes with some of the world's leading biologists. We're not a startup trying to find product-market fit, and we're not a pharma company optimizing a pipeline. We're building frontier AI for fundamental science, as open science, at a scale no one else is doing. This is a unique moment for scientific acceleration. The problems are among the hardest and most impactful problems you can choose to work on, and we move at a pace that meets this moment. Our research spans: Frontier molecular modeling, from protein language models (e.g., ESM) to structure prediction (e.g., ESMFold) and beyond. Scaled biological foundation models trained on some of the largest GPU clusters dedicated to science Imaging foundation models trained across the world's largest microscopy datasets Reasoning and agentic systems that connect frontier LLMs with biological foundation models Mechanistic interpretability of biological foundation models: extracting new biological knowledge directly from model weights Scientific data at unprecedented scale: AI systems to collect, curate, and learn from some of the richest biological datasets ever assembled Join Our Team! As a Research Scientist, you'll build the models and systems that define what AI can do in biology: foundation models, reasoning, reinforcement learning, and multi-agent systems at frontier scale. What You'll Do Build on and advance the AI systems at t

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 The Mission The Foundry is ClickUp's internal AI innovation lab — embedded inside GTM Systems and accountable for turning AI capabilities into production-grade, internally deployed products that make every GTM function faster and smarter. We build the infrastructure that powers AI-first work across Sales, Marketing, Post-Sales, and Revenue Operations. As the Senior Software Engineer on this team you will own the technical delivery of our MCP server platform, agent orchestration layer, and internal tooling — shipping production systems used daily by hundreds of ClickUp employees, and scaling your own throughput by treating AI tools as first-class engineering collaborators. What You'll Own MCP Server Platform Design, build, and operate Model Context Protocol servers that expose CRM, ticketing, analytics, and communication data to AI agents across the GTM stack Implement Okta PKCE authentication flows and RBAC policy enforcement so agents access only the data they're authorized to touch Maintain deployment infrastructure on AWS (Bedrock, Lambda, ECS, API Gateway) and contribute to GCP workloads where applicable Own observability: structured logging, distributed tracing, latency SLOs, and on-call runbooks for every production server Agent Orchestration & AI-Native Products Build and maintain multi-step autonomous agents that execute end-to-end GTM workflows — lead qualification, deal room assembly, onboarding automation, support triage, and more Architect prompt engineering frameworks, tool-call schemas, and agent evaluation harnesses that make AI behavior predictable and auditable Integrate with LLM p

About the Team OpenAI's mission is to ensure that artificial general intelligence benefits all of humanity. The Consumer Devices team is building a new generation of AI-powered products that seamlessly integrate hardware and software to create intuitive, transformative experiences. We bring together experts across embedded systems, machine learning, hardware, design, and product engineering to develop products at the intersection of AI and consumer technology. About the Role OpenAI is seeking a System Performance Engineer to profile, benchmark, and optimize performance across our embedded hardware products. In this role, you will work across operating systems, applications, camera and vision, graphics, and platform teams to define product KPIs, build performance tooling, and drive optimizations from early lab characterization through product launch and real-world usage. You will help establish the performance standards that shape the user experience of our products, ensuring they remain responsive, efficient, and reliable throughout their lifecycle. This role requires deep expertise in embedded or high-performance systems, strong operating systems fundamentals, and hands-on experience debugging under tight latency, power, and memory constraints. This role is based in San Francisco, CA. We use a hybrid work model of four days per week in the office and one day working remotely. Relocation assistance is available for new hires. In this role, you will: Develop system performance benchmarks, methodologies, and policies to evaluate end-to-end product behavior. Profile and analyze performance across key product use cases and workloads using custom and industry-standard profiling tools. Partner closely with engineering teams to identify bottlenecks and drive performance optimizations across the software stack. Define high-level product KPIs and establish measurement frameworks to measure launch readiness and monitor performance throughout the product lifecycle. Measure, re

About the Team The Cooperative AI team is scaling OpenAI with OpenAI. We are building a model powered knowledge system that evolves and learns as our products, systems and customers evolve. We leverage our state of the art models, technologies, and products (some external, some still in the lab) to assist or completely automate robust operations supporting both internal and external customers. We support OpenAI customers and internal partners globally, powering systems from customer support to integrity to product insights. We are a self-contained multi-disciplinary team, who enjoy a lightning fast feedback loop with customers at scale, some of whom sit just a few pods away. We iterate fast, and engineer for reliable long-term impact. We're constantly looking for the similarities and patterns in different types of work, and focus on building simple primitives, to apply world class knowledge to many domains. The work of this team exemplifies use of OpenAI technologies. We build systems so everyone can see the leverage that is possible with well designed AI-based implementations. We do this by working through internal use cases focused on Customers (specifically knowledge systems, automation systems, and automated agent systems) to prove impact, then we scale. About the Role We’re looking for a Backend Software Engineer to help architect and scale the infrastructure that powers our knowledge systems. This is a deeply technical and highly cross-functional role where you’ll build robust systems and backend services that serve as the foundation for how knowledge is created, accessed, and applied across OpenAI. In this role, you will: Design, build, and maintain backend services and APIs to support intelligent automation and knowledge systems Integrate and structure data across internal platforms, transforming it into formats optimized for use by downstream systems and AI workflows. Collaborate closely with product, research, and engineering teams to integrate OpenAI mode

About the Team The Cooperative AI team is scaling OpenAI with OpenAI. We are building an AI powered knowledge system that evolves and learns as our products, systems and customers evolve. We leverage our state of the art models, technologies, and products (some external, some still in the lab) to assist or completely automate robust operations supporting both internal and external customers. We support OpenAI customers and internal partners globally, powering systems from customer support to integrity to product insights. We are a self-contained multi-disciplinary team, who enjoy a lightning fast feedback loop with customers at scale, some of whom sit just a few pods away. We iterate fast, and engineer for reliable long-term impact. We're constantly looking for the similarities and patterns in different types of work, and focus on building simple primitives, to apply world class knowledge to many domains. The work of this team exemplifies use of OpenAI technologies. We build systems so everyone can see the leverage that is possible with well designed AI-based implementations. We do this by working through internal use cases focused on Customers (specifically knowledge systems, automation systems, and automated agent systems) to prove impact, then we scale. About the Role We’re looking for Software Engineers who're passionate about blending production-ready platform architecture with new tech and new paradigms. You’ll push the boundaries of OpenAI’s newest technologies to enable interactions and automations that are not only functional, but delightful. We value proactive, customer-centric engineers who can get the foundational details right (data models, architecture, security) in service of enabling great products. In this role, you will: Own the end-to-end development lifecycle for new platform capabilities and integrations with other systems Collaborate closely with engineers, data scientists, information systems architects, and internal customers to understand th

About the team: OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the role: We are seeking an experienced Optical Network Engineer to lead Laser related work within our optical interconnect efforts for large-scale compute systems. The role also requires broad, hands-on optical validation experience across IM/DD-based interconnects, working from lab characterization through production readiness and scaled deployment. In this role you will: Drive laser-focused requirements and technical direction within the broader optical interconnect roadmap. Lead evaluation and validation of optical components and subsystems, including laser-based elements, in lab and production-representative environments. Support end-to-end optical testing for IM/DD interconnects (e.g., module/system bring-up, characterization, debug, and readiness for scale). Work with external partners to align on development milestones, performance targets, and quality expectations. Own technical issue triage and resolution across performance, reliability, and manufacturability topics. Collaborate across internal teams to support integration, rollout, and operational success at scale. You might thrive in this role if you have: Strong experience in laser-focused optical engineering (development, validation, manufacturing readiness, or field support). Broad hands-on background with IM/DD optical technologies and optical test/debug workflows. Experience working with external suppliers/manufacturing partners and production-oriented execution. Demonstrated ability to debug complex t

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