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Lead Senior Python Engineer Jobs

6,753 active opportunities · Updated for October 2026

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Explore current lead senior python engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

BI
bswift India
📍 Bengaluru• Full-time
16 days ago

Want to be a bswifter? At bswift we’ve been transforming benefits administration since 1996, making it simpler, smarter, and more human. Our state-of-the-art, cloud-based technology and services empower employees to understand, manage, and love their benefits. From downtown Chicago, and remotely across the country, we serve thousands of companies and millions of people nationwide, reducing administrative burdens and freeing HR teams to focus on creating thriving, people-first workplaces. We’re looking for motivated and goal-driven individuals who share our passion for delivering excellence and creating solutions that make a difference. The reward is a fun, flexible and creative environment with ample opportunity for professional and personal growth. If you love the bswift values of pursue excellence, embrace accountability, deliver superior service, and be a great place to work, we want to hear from you! About the Role We are looking for an AI Engineer II to design, build, and deploy cutting-edge generative AI applications , including agentic workflows and intelligent chat experiences , that transform how employees interact with their benefits. This role goes beyond individual contribution—you will own complex AI features end-to-end , influence architecture decisions around LLMs and agent systems , and mentor junior engineers . You will play a key role in bringing secure, scalable, and high-performance AI solutions to production using AWS cloud technologies. You will collaborate closely with software engineers, architects, product managers, and cross-functional teams to deliver seamless and impactful user experiences Key Responsibilities 1. Solution Design & Development Lead the design and development of scalable, secure, and high-performance applications . Architect robust backend systems and integrate them with frontend applications and third-party services. Drive technical decisions and participate in design reviews alongside senio

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DU
17 days ago

About the Team DoorDash Labs is an independent team within DoorDash. We explore robotics and automation to transform last mile logistics in the long term. If you have a passion for applying robotics solutions in a service used by millions of people, then we want to talk to you! About the Role We are hiring a Software Integration Engineer for our Platform Integration team. This is a critical role with impact across the robot lifecycle, from manufacturing to daily operation. The Platform Integration team owns making sure the robot works as one cohesive system. The focus is on the interfaces between subsystems; this role in particular is focused on the software side handling interaction between: OS & software stack; firmware; networking; timing; and calibration. In this role, you will work cross functionally with our electrical, hardware, firmware, and autonomy engineers to support new functionality both in both hardware and software. This includes creating provisioning tools, functional tests, and supporting integration into the autonomy software stack. You will report to the Autonomy Platform Lead on our Autonomy Platform Team at DoorDash Labs. We expect this role to be hybrid with some time in-office and some time remote. You’re excited about this opportunity because you will… Play an integral role on a small and focused team. Lead system-level debug when an issue crosses subsystem boundaries or no single team can isolate it. Support early integration of new sensor and software component designs by identifying interface requirements, risks, dependencies and required checks. Design and maintain integration tests, test setups, and procedures to ensure subsystems, once combined, satisfy requirements and design intent. Build and maintain the mission-readiness checks used before manufacturing signoff, validation, field testing, or mission use for different robot platforms. Create the tools, checks, and debug guidance that Manufacturing Integration, Validation,

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S
Sigmoid
📍 Bengaluru• Full-time
17 days ago

Work Experience Required: 8 - 12 Years Experience in programing (Python, R, SQL, NoSQL,Spark) with ML tools & Cloud Technology (AWS, Azure, GCP) Experience in Python libraries such as numpy, pandas, scikit-learn, tensor-flow, scapy, scrapy, BERT etc. Good understanding in statistics, and ability to design statistical hypothesis testing to aid formal decision making. Develops predictive models using Machine Learning algorithms (SVM, Random Forest, Neural Network, Decision Tree, Logistic Regression, K-mean Clustering, linear regression, PCA etc.) Engaging with clients, understanding complex problem statements, and offering solutions in the domains of Retail, Pharma, Banking, Insurance, etc. Contribute to internal product development initiatives related to data science. Develop data science roadmap, and guide data scientist to meet their deliverables. Handling end-to-end client AI & analytics programs. Your role will be a combination of hands-on contribution, technical team management, and client interaction. Proven ability to discover solutions hidden in large datasets and to drive business results with their data-based insights Drive excellent project management required to deliver complex projects, including effort/time estimation. Be proactive, with full ownership of the engagement. Build scalable client engagement level processes for faster turnaround & higher accuracy Define Technology/ Strategy and Roadmap for client accounts, and guides implementation of that strategy within projects Run regular project reviews and audits to ensure that projects are being executed within the guardrails agreed by all stakeholders Manage the team-members, to ensure that the project plan is being adhered to over the course of the project Manage the client stakeholders, and their expectations, with a regular cadence of weekly meetings and status updates. Build a trusted advisor relationship with the IT management at clients and internal accounts leadership. Build

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LA
17 days ago

ROLE SUMMARY We are looking for a Senior Data Scientist to lead complex data science engagements that combine traditional statistical modelling with Generative AI. You will work hands-on with very large datasets across disparate systems and formats, translate ambiguous business problems into rigorous analytical solutions, and present those solutions clearly to C-level stakeholders. This is a delivery-first role with a fast track into technical leadership: alongside your own project work, you will help guide junior data scientists and shape how Lynx builds and ships data science solutions. KEY RESPONSIBILITIES Solution Design & Delivery Design and deliver end-to-end solutions for defined data science problems, combining classical modelling, data transformation, and Generative AI / LLM techniques. Work hands-on with very large datasets across disparate stores and formats, from ingestion and transformation through to modelling and validation. Apply statistical and machine learning methods to business problems such as customer retention, campaign management, and commercial performance optimisation. Client Communication & Leadership Present results and prepare client-ready materials for project stakeholders, including C-level audiences, translating technical work into clear business narratives. Lead smaller data science workstreams, with support from internal leadership and the PMO, including day-to-day guidance for junior team members. Partner with delivery and account teams to scope problems, set realistic timelines, and manage stakeholder expectations. Knowledge Building Create reusable documentation, presentations, and code libraries during projects so future engagements can build on prior work. Participate in internal education, research, and knowledge-sharing initiatives that raise the technical bar across the practice. SKILLS, QUALIFICATIONS AND EXPERIENCE 8+ years of overall experience in data science, with a track record of leading analytic

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Become a part of our caring community We are looking for a highly motivated Senior Technology Leadership professional to join our IT Operations team. You will support the Lead of the Application Operations Center and Enterprise Post Production Validation teams, with a focus on process automation, innovation, and continuous improvement. You will work with both onshore and offshore resources, ensuring in daily tasks, enhancing application support, and driving improvements in monitoring and validation processes. Main Responsibilities: Collaborate with the Lead to provide operational and strategic support for Application Operations Center and Post Production Validation teams. Identify, evaluate, and implement automation opportunities to increase efficiency and reduce manual workload. Drive process innovation by recommending and deploying advanced tools and methodologies for application operations and validation activities. Analyze existing workflows and develop documentation for standard operating procedures and best practices. Oversee daily application support and monitoring activities to ensure system stability, performance, and reliability. Partner with onshore and offshore teams to coordinate task execution and promote consistent adoption of new processes and technologies. Develop and maintain dashboards and reports to track key performance indicators and present findings to leadership. Ensure automation and process improvements comply with organizational standards and regulatory requirements. Facilitate knowledge sharing, training sessions, and change management activities to support team development and successful project implementation. Engage with stakeholders to gather requirements, understand challenges, and communicate progress on automation initiatives. Ability to create

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C
13 days ago

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Lead, Senior Decision Scientist serves as a strategic analytics and ideation leader supporting Payment Integrity Affordability initiatives with a primary focus on Fraud, Waste & Error (FWE) and Special Investigations Unit (SIU) programs. This role provides leadership and guidance to a team of Decision Scientists while driving the development, evaluation, and implementation of innovative opportunities that improve affordability outcomes and strengthen Payment Integrity capabilities. The Lead Decision Scientist is responsible for establishing analytical frameworks, managing ideation pipelines, defining success metrics, and identifying cross-functional opportunities that create enterprise value across Payment Integrity programs. Required Qualifications 7+ years of experience in healthcare analytics, Payment Integrity, Fraud, Waste & Error (FWE), Special Investigations, or related healthcare operations. 5+ years of experience leading analytical projects or providing technical leadership within a healthcare environment. Demonstrated experience working with healthcare claims platforms including ACAS, QNXT, HRP, or comparable systems. Experience using SAS, SQL, Python, R, or other analytical and statistical programming languages. Experience performing advanced data analysis, opportunity identification, trend analy

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The mission of The New York Times is to seek the truth and help people understand the world. That means independent journalism is at the heart of all we do as a company. It’s why we have a world-renowned newsroom that sends journalists to report on the ground from nearly 160 countries. It’s why we focus deeply on how our readers will experience our journalism, from print to audio to a world-class digital and app destination. And it’s why our business strategy centers on making journalism so good that it’s worth paying for. About the Role NYT Wirecutter is looking for a Senior Manager, Revenue Analytics to power our business strategy. Your core mandate is to increase audience monetization across our primary businesses—Affiliate, Advertising, and E-commerce—ensuring we preserve long-term audience trust. As a player-coach role, you will lead a team of analysts and partner closely with Revenue, Product, and Marketing leads to establish KPIs, run conversion experiments, and build attribution frameworks that scale revenue. You will report to the Executive Director, Data Analytics. Responsibilities You will lead, mentor, and onboard a team of two direct reports, nurturing their career growth You will analyze affiliate revenue drivers (e.g., merchant commissions, EPC, conversion rates, and partner yield) across all content touch points. You will be the analytics lead for the newly launched Wirecutter Store, reporting on unit economics, merchandise performance, cart funnel analytics, order value (AOV), and customer acquisition/repeat purchase metrics You will partner with Ad Ops and Advertising teams to track ad yield (RPM, eCPM), fill rates, and ad unit viewability, balancing display and custom content revenue against user experience and page speed You will evaluate trade-offs between affiliate links, ad placements, and Wirecutter Store product placements on site, creating a holistic monetization framework to maximize total revenue per user. You will lead recur

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L
1mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. The Growth Products team drives rider and driver acquisition to scale the business and balance the marketplace. We specialize in incentive and messaging targeting, budget optimization, and paid media measurement, and move rapidly to test new ideas and products. As a Data Scientist expert in causal inference and marketing mix models (MMM), you will lead our efforts to measure and optimize investments across marketing channels. Responsibilities: Deliver results across the entire lifecycle of data science solutions for Growth: from defining the problem with cross-functional stakeholders to deploying production models that address key business problems. Own complex domains and develop long-term roadmaps to maximize business impact. Build statistical pipelines, write production code, and design/analyze experiments. Participate in the science on-call rotation to ensure automated campaigns operate successfully. Experience: Advanced degree in statistics, economics, mathematics, or equivalent industry experience. 4+ years of industry experience in causal inference or data science. Proven ability to apply statistics to unstructured problems and deliver measurable results. Deep technical expertise in causal inference and tackling challenging measurement problems. Expertise in marketing mix modeling is highly preferred. Expertise in SQL and experience with large-scale data platforms. Proficiency in Python and working within production coding environments. Benefits: Great medical, dental, and vision insurance options with additional programs available when enrolled Mental health benefits Family building benefits Child care and pet benefits 401(k) plan with company match to help save for your future In addition to 12 observed holidays, salaried team members have discretionary paid time off, hourly team membe

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L
Lyft
📍 San Francisco• Full-time
1mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. The Growth Products team drives rider and driver acquisition to scale the business and balance the marketplace. We specialize in incentive and messaging targeting, budget optimization, and paid media measurement, and move rapidly to test new ideas and products. As a Data Scientist expert in causal inference and marketing mix models (MMM), you will lead our efforts to measure and optimize investments across marketing channels. Responsibilities: Deliver results across the entire lifecycle of data science solutions for Growth: from defining the problem with cross-functional stakeholders to deploying production models that address key business problems. Own complex domains and develop long-term roadmaps to maximize business impact. Build statistical pipelines, write production code, and design/analyze experiments. Participate in the science on-call rotation to ensure automated campaigns operate successfully. Experience: Advanced degree in statistics, economics, mathematics, or equivalent industry experience. 4+ years of industry experience in causal inference or data science. Proven ability to apply statistics to unstructured problems and deliver measurable results. Deep technical expertise in causal inference and tackling challenging measurement problems. Expertise in marketing mix modeling is highly preferred. Expertise in SQL and experience with large-scale data platforms. Proficiency in Python and working within production coding environments. Benefits: Great medical, dental, and vision insurance options with additional programs available when enrolled Mental health benefits Family building benefits Child care and pet benefits 401(k) plan with company match to help save for your future In addition to 12 observed holidays, salaried team members have discretionary paid time off, hourly team membe

pythonsqlai
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L
1mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. The Growth Products team drives rider and driver acquisition to scale the business and balance the marketplace. We specialize in incentive and messaging targeting, budget optimization, and paid media measurement, and move rapidly to test new ideas and products. As a Data Scientist expert in causal inference and marketing mix models (MMM), you will lead our efforts to measure and optimize investments across marketing channels. Responsibilities: Deliver results across the entire lifecycle of data science solutions for Growth: from defining the problem with cross-functional stakeholders to deploying production models that address key business problems. Own complex domains and develop long-term roadmaps to maximize business impact. Build statistical pipelines, write production code, and design/analyze experiments. Participate in the science on-call rotation to ensure automated campaigns operate successfully. Experience: Advanced degree in statistics, economics, mathematics, or equivalent industry experience. 4+ years of industry experience in causal inference or data science. Proven ability to apply statistics to unstructured problems and deliver measurable results. Deep technical expertise in causal inference and tackling challenging measurement problems. Expertise in marketing mix modeling is highly preferred. Expertise in SQL and experience with large-scale data platforms. Proficiency in Python and working within production coding environments. Benefits: Great medical, dental, and vision insurance options with additional programs available when enrolled Mental health benefits Family building benefits Child care and pet benefits 401(k) plan with company match to help save for your future In addition to 12 observed holidays, salaried team members have discretionary paid time off, hourly team membe

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Notice to applicants: We have seen a rise in recruitment scams. Please note that outreach from Khan Academy recruiters will only come from the @khanacademy.org domain. Our team does not use Gmail or other personal accounts for contacting potential candidates. Khan Academy will never solicit money, equipment fees, or sensitive financial information at any stage of the hiring process. We also do not work with external recruiting agencies, so outreach from headhunters presenting opportunities on behalf of Khan Academy is illegitimate. Please always check the email domain and cross-reference the position with the official Khan Academy Careers page to confirm an opening is valid. ABOUT KHAN ACADEMY Khan Academy is a nonprofit with the mission to deliver a free, world-class education to anyone, anywhere. Our proven learning platform offers free, high-quality supplemental learning content and practice that cover Pre-K - 12th grade and early college core academic subjects, focusing on math and science. We have over 181 million registered learners globally and are committed to improving learning outcomes for students worldwide, focusing on learners in historically under-resourced communities. ABOUT KHAN ACADEMY KIDS Khan Academy Kids is a free and fun learning program for children ages 2 to 8. Kodi Bear and a cast of animated characters lead children on a personalized education journey filled with fun, standards-aligned activities in early literacy, math, executive functioning and social emotional skills. Built by a small but mighty team, Khan Academy Kids is used by millions of children in homes and classrooms around the world. OUR COMMUNITY Our students, teachers, and parents come from all walks of life, and so do we. Our team includes people from academia, traditional/non-traditional education, big tech companies, and tiny startups. We hire great people from diverse backgrounds and experiences because it makes our company stronger. We value diversity, equity,

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G
Gilead
📍 California• $169.3K – $219.1K/yr
10 days ago

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. The Protein Therapeutics department is seeking a highly motivated laboratory-based scientist to lead the Molecular Biology function within the Mammalian Expression team. In this capacity

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Altana is the network for trusted trade. Our AI-powered product network empowers governments and businesses to build a more resilient and secure global economy while keeping trade flowing. The Role: Vertical Technology Lead, Policy & National Security Altana’s mission is to power a new era of globalization organized around trusted networks. Nowhere is that mission more consequential — or more demanding — than in the policy and national security community, where the questions our customers bring us are matters of sovereignty, security, and how a nation understands the networks it depends on. These are the hardest programs we run. The technical bar is high and it keeps rising: the biggest opportunities are won, kept, and expanded on the strength of the technical work itself — sometimes on technical capability alone. As these engagements grow, so does the machinery large government partners expect from a serious partner: program management, delivery cadence, contractual rigor, accreditation. Left unmanaged, that machinery swamps the very people whose job is to architect and build. We’re changing how we deliver so it doesn’t. Large and strategic accounts are staffed with dedicated Implementation Delivery Managers (IDMs) who carry the program, project, and delivery-management load — and, as an account grows more complex, we trade up the team to meet it. That frees the technical leadership of the vertical to do what only it can do: hold the architecture bar, win the technical argument, and drive the last mile of product where the mission needs something that doesn’t exist yet. As Vertical Technology Lead for Policy & National Security, you own the technical outcomes for the vertical end-to-end. You are the senior technical counterpart to the vertical’s commercial leadership — setting the technical approach that wins business, owning the solution architecture and delivery that turns wins into mission outcomes, and leading the team that does the work. This is a UK-b

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Altana is the network for trusted trade. Our AI-powered product network empowers governments and businesses to build a more resilient and secure global economy while keeping trade flowing. The Opportunity at Altana As a Global Public Sector Implementation Delivery Manager (IDM), you are the single-threaded technical owner of delivery for one of Altana’s most important public sector accounts or organizations. You blend enterprise architecture, hands-on deployment, and product design and development with the relationship skills to be the trusted technical voice in the room for the mission owners you serve. You lead a small, account-aligned implementation pod and are accountable for turning a closed-won account into mission outcomes: architecting the deployment, delivering it in secured and regulated environments, keeping it healthy, and finding the next place Altana can create value. You do this hip-to-hip with commercial — partnering with the Technical Account Managers (TAMs) and Program Managers who run the account — using delivery credibility to enable organic growth and inside sales without carrying the commercial number yourself. This role reports to a GPS Implementation sub-vertical lead (Trade, Resilience, or Policy) within the Implementation function, and is deployed against a named strategic account. For example, an IDM aligned to U.S. Customs and Border Protection (CBP) would report to the Trade sub-vertical lead. Your Responsibilities Own delivery outcomes for a named strategic account or account groups. Serve as the single-threaded technical owner for implementation and platform delivery to a key public sector account or organization, from post-award through sustainment. Deliver on-time against contractual commitments and hold the technical quality bar. Set and steward the account architecture. Translate mission outcomes into a coherent enterprise/solution architecture across SaaS and regulated PaaS environments. Own the deployment, integration, and data-m

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H
Hyreo
📍 Bengaluru• Full-time
16 days ago

About Team: Financial Planning and Analysis” (FP&A) team works closely with the CFO, FP&A head, and all the other functions to enable and improve data-driven decision-making. The team enables financial planning, and allocation of funds, and uses structured problem-solving approaches along with a wide range of statistical / operations research techniques to create productized solutions for business teams to consume. Role: We are seeking to hire a talented Finance Professional for the FP&A team. This role offers a wide spectrum of responsibilities spanning from Financial and strategic planning, dynamic resource allocation framework for growth and P&L sustainability, driving efficiency charters across the P&L line items, performance management, business analytics and benchmarking with external companies. Responsibilities: Prepare monthly, quarterly and annual financial plans to be executed. Hold guardrails for investment to maximize topline growth Develop financial model for planning, budgeting, variance analysis and performance management Strategic Planning, AOP and LRP creation with thorough and detailed how-lists for topline and P&L line items Lead the MEC process with stakeholders from Business Finance and Controllership. Action upon the key risks and opportunities with agility Identify opportunities for efficiencies across the org and partner with respective teams to develop action plan to maximize the returns on investment for topline growth as well as cost optimization Leverage SQL to extract and manipulate financial data for analysis, Create and maintain dashboards and reports using SQL based tools Handle complex ad hoc request with a shorter turnaround time and supplement such request with appropriate analysis and insights for enabling business decision-making Assessment and dissemination of impact on business due to macro trends, benchmarking with national and international peer companies to identify the

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