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Lead Software Development Engineer Jobs

10,000 active opportunities · Updated for October 2026

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Explore current lead software development engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

B
Biohub
📍 Redwood City• Full-time• Hybrid• $83K – $103K/yr
2mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The Biohub is a group of nonprofit research institutes that bring together scientists, engineers, and physicians with the goal of pursuing grand scientific challenges on 10- to 15-year time horizons. The Biohub focuses on understanding underlying mechanisms of disease and developing new technologies that will lead to actionable diagnostics and effective therapies. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at the Biohub facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and perspectives are at the heart of Biohub and enable disruptive innovation and scholarly excellence. We are committed to cultivating an organization where all colleagues feel inspired and know their work makes an important contribution. This role sits at the interface of two closely connected efforts within our Dynamic Structural Biology group, which maps the molecular architecture of living cells — charting how protein complexes assemble, where they localize, and how their organization shifts across cell states and in response to perturbation. We develop and operate advanced imaging workflows to resolve the structure of signaling organelles such as primary cilia and lysosomes. Together we develop and deploy cutting-edge cryo-electron tomography, proteomics, and correlative imaging ap

pythonrestai
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D
2mo ago

SLSQ227R802 The Global GCP Cloud Alliance, Go-To-Market Strategy & Business Development team owns these three domains with one of our most strategic cloud partners. Reporting to the Global VP, Databricks on GCP Business Unit, and Go-To-Market Strategy & Business Development will recruit, hire and lead a team of highly talented individuals that are obsessed with helping data teams solve the world’s toughest problems with Databricks on GCP. The impact you and your team will have: Design, launch, and scale a comprehensive Databricks on GCP Go-To-Market strategy that accelerates customer business outcomes, grows Databricks consumption, and increases long-term commitments to our lakehouse platform. Define, build, execute and measure the ongoing performance of joint horizontal and industry vertical sales plays with Databricks, GCP, and C&SI Partners to unlock new sales opportunities. Enhance Databricks’ strategic relationship with GCP leaders and executives across product, sales, solution architecture, business development, and partner teams. Motivate GCP sales teams to adopt the Databricks Lakehouse paradigm for our mutual customers' most essential Data and AI initiatives. Unlock value for Databricks, GCP and our mutual customers by identifying, prioritizing and facilitating high value product integrations with GCP services Strengthen the Databricks & GCP alliance by accelerating GCP Partner Program and GCP Marketplace innovations Build a foundation for future growth to help us scale Databricks What we look for: 15+ years of experience in business development, enterprise sales, go-to-market strategy, consulting and product management with companies that are focused on SaaS, cloud computing, analytics, machine learning, artificial intelligence or similar technologies. 5+ years of experience building and leading high-functioning teams and delivering results through others 3+ years of GCP or extended ecosystem experience Ability to attract,

gcpmachine learningartificial intelligence
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L
2mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Flexdrive is a subsidiary of Lyft that works together with Lyft teams to realize our shared mission. At Flexdrive, we're at the forefront of revolutionizing transportation by building the operational backbone for autonomous vehicle (AV) fleets. As a leader in fleet management, we're leveraging our expertise to enter the AV space, forming strategic partnerships with cutting-edge technology providers. We're looking for dedicated team members to help us pioneer this new chapter, starting with our first AV depot in Nashville, Tennessee. Reporting to the Depot Operations Lead , Flexdrive is seeking detail-oriented and technically capable Depot Operations Associates to ensure our autonomous vehicle fleet maintains optimal readiness for 24/7 operations. This hands-on role combines critical vehicle preparation, maintenance support, and calibration responsibilities that directly impact fleet availability and safety. You will be responsible for the complete vehicle lifecycle from pre-deployment checks through end-of-day diagnostics, including specialized calibration procedures that enable autonomous operation. This position offers a unique opportunity to work with cutting-edge autonomous vehicle technology while developing expertise in AV operations, safety protocols, and technical procedures. If you're passionate about being part of the future of transportation and thrive in a fast-paced, detail-oriented environment, we encourage you to apply. Work Schedule & Shift Availability This role supports 24/7 AV depot operations and requires availability to work afternoon shift, with hours scheduled between 09:30 PM - 7:00 AM. Specific shift times and schedules will be determined based on operational needs and business requirements. Schedules may include weekends and holidays based on depot operationa

logistics
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L
2mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Flexdrive is a subsidiary of Lyft that works together with Lyft teams to realize our shared mission. At Flexdrive, we're at the forefront of revolutionizing transportation by building the operational backbone for autonomous vehicle (AV) fleets. As a leader in fleet management, we're leveraging our expertise to enter the AV space, forming strategic partnerships with cutting-edge technology providers. We're looking for dedicated team members to help us pioneer this new chapter, starting with our first AV depot in Nashville, Tennessee. Reporting to the Depot Operations Lead , Flexdrive is seeking detail-oriented and technically capable Depot Operations Associates to ensure our autonomous vehicle fleet maintains optimal readiness for 24/7 operations. This hands-on role combines critical vehicle preparation, maintenance support, and calibration responsibilities that directly impact fleet availability and safety. You will be responsible for the complete vehicle lifecycle from pre-deployment checks through end-of-day diagnostics, including specialized calibration procedures that enable autonomous operation. This position offers a unique opportunity to work with cutting-edge autonomous vehicle technology while developing expertise in AV operations, safety protocols, and technical procedures. If you're passionate about being part of the future of transportation and thrive in a fast-paced, detail-oriented environment, we encourage you to apply. Work Schedule & Shift Availability This role supports 24/7 AV depot operations and requires availability to work afternoon shift, with hours scheduled between 12:00 PM - 11:00 PM. Specific shift times and schedules will be determined based on operational needs and business requirements. Schedules may include weekends and holidays based on depot operation

logistics
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L
2mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Flexdrive is a subsidiary of Lyft that works together with Lyft teams to realize our shared mission. At Flexdrive, we're at the forefront of revolutionizing transportation by building the operational backbone for autonomous vehicle (AV) fleets. As a leader in fleet management, we're leveraging our expertise to enter the AV space, forming strategic partnerships with cutting-edge technology providers. We're looking for dedicated team members to help us pioneer this new chapter, starting with our first AV depot in Nashville, Tennessee. Reporting to the Depot Operations Lead , Flexdrive is seeking detail-oriented and technically capable Depot Operations Associates to ensure our autonomous vehicle fleet maintains optimal readiness for 24/7 operations. This hands-on role combines critical vehicle preparation, maintenance support, and calibration responsibilities that directly impact fleet availability and safety. You will be responsible for the complete vehicle lifecycle from pre-deployment checks through end-of-day diagnostics, including specialized calibration procedures that enable autonomous operation. This position offers a unique opportunity to work with cutting-edge autonomous vehicle technology while developing expertise in AV operations, safety protocols, and technical procedures. If you're passionate about being part of the future of transportation and thrive in a fast-paced, detail-oriented environment, we encourage you to apply. Work Schedule & Shift Availability This role supports 24/7 AV depot operations and requires availability to work afternoon shift, with hours scheduled between 6:30 AM - 3:00 PM. Specific shift times and schedules will be determined based on operational needs and business requirements. Schedules may include weekends and holidays based on depot operational

logistics
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A
Anthropic
📍 San Francisco• $240K – $325K/yr
2mo ago

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role We are seeking a Machines FP&A lead to own financial planning for the chips and accelerators that run our models. You will own the hardware forecast and budget, keep leadership's view of machine spend current, and be the single finance point of contact for machines into Accounting and consolidated FP&A. In this role, you will be a key partner to our capacity planning and hardware teams, and work day to day with the Compute deal team, Accounting, and the consolidated FP&A team. Key responsibilities Own the hardware forecast: delivery volumes, lease and financing expense, and cash flows Run budget vs. actuals for machine spend: one view of what the fleet costs and why it moved Serve as the single point of contact for machines in forecast and close cycles with Accounting and consolidated FP&A Coordinate forecast inputs with Capacity Planning and the Compute deal team Track spend and cash-flow phasing against multi-year hardware commitments Partner with Accounting on the treatment of leases and related agreements Support chip and accelerator economics analyses led by the Machines finance team Build the reporting that keeps leadership's machine spend picture current Minimum qualifications Owned a forecast or budget end to end at a hardware, semiconductor, hyperscaler, or infrastructure-heavy business Strong driver-based modeling skills and budget-vs-actual / variance discipline Comfort partnering closely with engineering and commercial teams under deal-timeline pressure Passion for Anthropic's mission to build safe, transformative AI systems Preferred qualifications 7+ years in FP&A, strategic finance, or

aiaccountingfinance
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S
Snowflake
📍 District of Columbia, United States• Full-time
2mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. PRINCIPAL PRACTICE MANAGER LEAD. STRATEGIZE. TRANSFORM. JOIN US AS A PROFESSIONAL SERVICES PRACTICE MANAGER! Are you ready to own your impact at the forefront of the AI and data revolution ? As a Principal Practice Manager , you’ll be a key driver in transforming the US Federal government through cutting-edge AI-cloud data solutions . You’ll collaborate with top-tier clients, strategize with elite sales teams, and win and lead groundbreaking professional service engagements —all while working with the best minds in the industry! This role is completely remote but preference will be given to those in the DC-metro area. WHY THIS ROLE? Be a Market Leader: Own and execute the strategic vision for Professional Services across all of the US Federal Government for Defense and Civilian. Drive Meaningful Change: Work with clients to unlock the power of AI and data and fuel digital transformations. Collaborate with the Best: Work cross-functionally with top industry experts to win transformative services opportunities and shape the future of cloud data solutions. Grow your Business: Work proactively across accounts to create and mature new opportunities, close deals and grow your business. Crush Your Goals: Meet and exceed bookings, revenue, and consumption targets while delivering e

C
Clickup
📍 United States• Full-time• Remote• $250K – $300K/yr
2mo ago

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 Come lead the Identity & Access Management Platform team (IAM Platform) — the foundational layer that decides who can see and do what across all of ClickUp. This team owns the authorization engine, the permission and role model, authentication (SSO, MFA, SCIM, OIDC), sharing primitives, audit logs, and the core data model and APIs that define how customers' work is organized and nested across the product — the foundation every other part of ClickUp is built on. It is backend-heavy, high-blast-radius work. As we move upmarket, this is some of the most important and security-sensitive work we do — enterprises decide whether they can trust us based on how precise, predictable, auditable, and manageable our access controls are. We're looking for a Senior Engineering Manager to lead and grow this team. Your mandate is twofold: deliver an enterprise-grade access management platform — extensible, configuration-driven, correct and auditable by design — and build the team that will carry it , hiring and developing engineers as we invest heavily in enterprise. You'll raise the access, identity, and admin capabilities enterprises depend on to an enterprise-grade standard and keep them there, partnering with a Staff engineer on technical direction while you own delivery, people, and priorities. Just as important: you'll run this team the way ClickUp runs — AI-native . We structure work so AI agents can read it, route it, roll it up, and report on it, so a small team amplified by agents operates at a different scale. There are no status-reporting meetings; agents keep status, progress, and health current from r

REMOTEmachine learningartificial intelligenceai
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NH
Noctrix Health
📍 Pleasanton• $230K – $250K/yr
2mo ago

Noctrix Health is redefining the treatment of chronic neurological disorders with clinically validated therapeutic wearables. Our team of medical device specialists, neuroscientists, and consumer electronics engineers is dedicated to delivering prescription-grade therapy with an outstanding user experience. We have pioneered the world’s first drug-free wearable therapy, clinically proven to alleviate symptoms in adults with drug-resistant Restless Legs Syndrome (RLS). Join us in transforming healthcare, improving lives, and driving meaningful change through innovative medical technology. We are seeking an experienced and strategic Director, Clinical Affairs to lead the planning, execution, and oversight of clinical studies supporting the development, regulatory approval, reimbursement, and commercialization of Noctrix Health’s medical devices. This leader will be accountable for the successful delivery of clinical programs, ensuring studies are executed efficiently, compliantly, on schedule, and within budget while generating high-quality clinical evidence that supports regulatory and business objectives. The Director, Clinical Affairs will serve as a key cross-functional leader and liaison among Clinical Affairs, Clinical Research, Regulatory Affairs, Quality, Product Development, and external partners. This individual will provide leadership across clinical operations, including sponsor oversight, site management, CRO and vendor management, clinical data quality, study execution, and evidence generation. This position reports to the Senior Vice President, Clinical & Regulatory Affairs . This is a full-time, hybrid position that is located at our Pleasanton headquarters. Responsibilities: Lead the planning, execution, and oversight of medical device clinical studies from study start-up through close-out Contribute to clinical development strategies supporting product development, regulatory submissions, reimburse

gcpproject management
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O
2mo ago

About the Team OpenAI's Enterprise team builds AI-powered enterprise products and shared platform capabilities that help organizations put advanced AI to work securely and at scale. Our work spans enterprise workflows, agent experiences, integrations, identity, administration, security, governance, and deployment. About the Role As a Technical Program Manager on Enterprise, you will lead the technical strategy and execution behind the products and shared capabilities that make ChatGPT, Codex, and future OpenAI products useful, secure, and scalable for organizations. You will translate customer needs, competitive dynamics, and product priorities into actionable plans, influence architectural direction, and deliver durable capabilities across application, platform, and infrastructure layers. The role requires deep technical fluency, strong product judgment, and the ability to move between hands-on execution and broader enterprise strategy. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Drive technical strategy and execution for enterprise product and AI workflow initiatives, from design through implementation, launch, customer rollout, and iteration. Partner with engineering teams to influence architectural direction, interface definitions, and implementation tradeoffs across full-stack products, APIs, integrations, and shared platform systems. Translate enterprise customer requirements into actionable product priorities across AI-powered workflows, agent experiences, integrations, permissions, data access, evaluations, identity, security, governance, and deployment readiness. Represent the needs of enterprise buyers, IT administrators, security teams, business leaders, developers, and end users in product and technical decisions. Identify adoption barriers, competitive gaps, and opportunities to make OpenAI products easier for organizations

awsrestai
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A
Anthropic
📍 San Francisco• $240K – $325K/yr
2mo ago

About Anthropic Anthropic’s mission is to create reliable, interpretable, and steerable AI systems. We want AI to be safe and beneficial for our users and for society as a whole. Our team is a quickly growing group of committed researchers, engineers, policy experts, and business leaders working together to build beneficial AI systems. About the role We are seeking a Strategic Finance Lead to provide finance leadership for our accelerator investments. In this role, you will be a key partner to our compute teams, providing financial expertise and guidance to optimize our compute investments and drive strategic decision-making. In this role, you’ll develop deep expertise in the economics of AI compute, from the unit economics of individual training runs to the long-range financial planning of our accelerator fleet. You’ll build financial models that inform Anthropic’s investment decisions, own planning and forecasting processes for major cost centers, and translate complex technical dynamics into clear financial narratives for leadership. This is a high-impact role for someone who thrives at the intersection of finance and technology, and who is energized by building frameworks from scratch in a fast-moving environment. Key responsibilities Finance lead for cloud accelerator compute spend, including budgeting, monthly forecasting, variance analysis, and financial plan maintenance Build and maintain detailed bottoms-up data-driven financial models for accelerator infrastructure, including long-range forecasts, cost driver analyses, and investment scenario modeling Develop deep expertise in compute contracts, pricing structures, and cost drivers, and surface optimization opportunities across our infrastructure Serve as subject matter expert for Anthropic’s overall compute capacity plan, owning source of truth and plan of record Support the implementation and management of financial planning tools (e.g., Pigment), ensuring our models and processes scale with the organiza

pythonsqlaws
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O
OpenAI
📍 San Francisco• Full-time• Remote• $205K – $335K/yr
2mo ago

About the Team OpenAI's Industrial Compute organization is building the world's most advanced AI infrastructure ecosystem. Through strategic partnerships and self-built campuses, we are scaling one of the world's fastest-growing AI infrastructure platforms. The Supply Chain organization ensures critical infrastructure components—from compute systems and networking equipment to integrated rack solutions—are sourced, manufactured, qualified, and delivered with the speed and reliability required to support frontier AI development. We partner closely with Hardware Engineering, Manufacturing Quality Engineering, Infrastructure Delivery, Hardware Operations, Finance, and suppliers worldwide to build a resilient, scalable supply chain capable of supporting rapid infrastructure expansion. As Industrial Compute continues to grow, Supply Chain serves as the operational bridge between engineering innovation and large-scale infrastructure deployment. About the Role We are seeking a Supply Chain Manager to lead strategic execution across sourcing, supplier operations, manufacturing quality, and infrastructure delivery for OpenAI's AI infrastructure portfolio. This role will oversee a multidisciplinary team responsible for strategic sourcing, manufacturing quality engineering, and technical program management while partnering closely with engineering, finance, hardware operations, and deployment teams. You will drive supplier strategy, manufacturing readiness, production planning, quality performance, and operational execution across the full hardware lifecycle. Success requires balancing long-term supplier strategy with day-to-day execution. You'll establish scalable operating mechanisms, strengthen supplier partnerships, manage complex cross-functional programs, and ensure OpenAI can rapidly deploy AI infrastructure without compromising quality, cost, or reliability. This is a people leadership role responsible for developing a high-performing organization while driving operati

REMOTEartificial intelligenceaifinance
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At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Sitting within the broader Safety & Customer Care team, Lyft's Customer Care Operations organization manages over 1.7 million monthly customer interactions and serves as the company's primary direct touchpoint with riders, drivers, and businesses — spanning frontline support across multiple customer segments, a global BPO workforce, and the central functions that enable them to operate at scale. The Director of Business Planning & Central Operations is a newly created role at the center of how Customer Care runs and grows. This leader will ensure the org is resourced and positioned for the future, and will own the functions that keep Customer Care financially disciplined and execution-ready. Reporting to the Senior Director of Customer Care Operations, they will lead five functions: Planning & Forecasting, Workforce Management, Readiness & Integration, Vendor Management, and Support Excellence. What You'll Do Business Planning & Strategy Partner with the Senior Director to drive H1 and H2 planning — translating annual objectives into operational plans, investment decisions, and resource models. Lead the investment brief process: sizing opportunities, articulating trade-offs, and building the business cases that secure resourcing for strategic priorities. Drive capacity planning, scenario modeling, and long-range forecasting to ensure the internal and external workforce scales efficiently alongside platform growth and AI adoption. Define and operationalize OKRs across the portfolio, then build the rhythms and infrastructure — scorecards, business reviews, and performance dashboards — that hold teams accountable and give leadership clear visibility into progress and outcomes. Growth & Integrations Lead operational readiness for major product launches, external partnerships, and

aigorust
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C
2mo ago

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 What You’ll Own Lead, coach, and develop a team of Account Executives focused on the commercial segment across AMER. Drive pipeline generation, deal execution, and consistent attainment of regional revenue targets. Build a strong operating cadence around forecasting, pipeline inspection, deal reviews, rep development, and performance management. Hire, ramp, and retain high-performing talent while creating an ambitious, inclusive, and motivating team culture. Improve sales process scalability through better use of CRM data, performance metrics, and repeatable best practices. Partner closely with Growth, Marketing, Operations, and Product to improve conversion, support important accounts, and remove friction in the customer journey. Reinforce high standards for thoughtful, value-based selling and customer-first leadership. Report on performance, pipeline health, forecast accuracy, and improvement opportunities to senior leadership. Required Qualifications Significant experience leading B2B SaaS sales teams in a commercial, SMB, or mid-market motion. Strong understanding of selling across AMER markets and how regional nuance shapes coaching, hiring, and execution. Proven track record coaching high-performing sellers and improving team productivity, forecast quality, and revenue outcomes. Experience building or scaling repeatable new-business and outbound motions. Strong analytical and operational instincts, with comfort using CRM data, sales metrics, and pipeline insights to drive decisions. Excellent communication, collaboration, and change-management skills. Ability to influence partners across Marketin

awsmachine learningai
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About Comfrt Comfrt is one of the fastest-growing direct-to-consumer apparel brands, redefining what comfort means through elevated essentials designed for everyday life. Our mission goes beyond clothing—we are building a global community centered around comfort, confidence, mental wellness, and inclusivity. About the Role As Comfrt continues to expand across retail, wholesale, and experiential channels, we are seeking a strategic and commercially minded Senior Director of Retail Marketing to lead our physical brand experience. This role will own the strategy and execution of Comfrt’s retail marketing ecosystem, including store launches, retail experiences, wholesale partnerships, local market activations, and customer engagement initiatives. Working cross-functionally with Brand, Creative, Retail Operations, Merchandising, Marketing and Growth teams, you will develop scalable retail marketing strategies that strengthen brand awareness, drive traffic and revenue, and support Comfrt’s continued expansion. Key Responsibilities Retail Marketing Strategy Develop and execute Comfrt’s retail marketing strategy, ensuring alignment with the company’s overall brand and business objectives. Translate seasonal campaigns, product launches, and curated brand moments into impactful retail experiences across new stores, pop-ups, and future retail formats. Establish scalable retail marketing frameworks, playbooks, and brand standards that ensure consistency across all physical touchpoints. Partner with cross-functional teams to create integrated omnichannel campaigns that connect physical and digital customer experiences. Lead full funnel marketing initiatives to drive traffic and sales for retail stores - including localized digital and paid media campaigns, in store and community events, influencer and creator partnerships, and affiliate programs - in partnership with the Growth, Social, and CRM teams. Store Openings & Market Expansion Lead marketing strategy for new store op

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