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Mission Systems Engineers Jobs

6,678 active opportunities · Updated for October 2026

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Explore current mission systems engineers jobs. Use filters to narrow by work mode, employment type, experience and date posted.

C
Coinbase
📍 - USA• Full-time• Remote• From $186.1K/yr
1mo ago

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . As a Senior Software Engineer on the AI Platform team within the Platform group, you'll build and operate the LLM and agent infrastructure that every team at Coinbase depends on. This team owns the company's single path to large language models and the full agent lifecycle: build, deploy, run, observe, and improve. You'll lead multi-quarter technical initiatives across the platform, from gateway and runtime systems to knowledge bases and applied AI agents, directly shaping how Coinbase scales AI across the organization. What you'll do: Own the architecture and delivery of core platform systems including the LLM Gateway (60+ models, auth, PII redaction, fallbacks, cost optimization), AI Hub, and agent runtime with microVM sandboxes and governed MCP gateway Drive the design and implementation of Knowledge Base infrastructure, connecting data sources to auto-provisioned vector and markdown stores queryable by any agent Lead AI FinOps capabilities including spend attribution, governance, and cost optimization across all AI workloads company-wide Partner across engineering, security, legal, finance, product, and external partners at frontier labs and major cloud providers to ship high-impact platform capabilities Build evaluation and observability tooling including LLM-as-judge harnesses, full tracing, and feedback loops that let subject matter experts refine production a

REMOTEpythonawsmicroservices
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C
Coinbase
📍 - USA• Full-time• Remote• From $186.1K/yr
1mo ago

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . As a Senior Software Engineer on the Blockchain Networks team within the Platform group, you'll build the critical infrastructure that integrates blockchain protocols with Coinbase's internal services for new assets, stablecoins, and staking. This team translates complex blockchain operations and state machines into simple, reliable APIs that product teams across Coinbase depend on. You'll own multi-quarter technical initiatives and ship platform primitives that directly improve the latency, reliability, and cost of our crypto stack. What you'll do: Own the design and delivery of blockchain network infrastructure that abstracts blockchain complexity into reliable, platform APIs Lead multi-quarter initiatives including new chain integrations, re-architecture efforts, and data migrations that improve system latency, reliability, and cost Define and maintain APIs, SLOs, and observability for the systems you build, including on-call ownership Partner with product and platform teams to establish data contracts and ship SDKs and platform primitives that drive adoption across Coinbase Build deep technical context across multiple top blockchain protocols (e.g., Bitcoin, Ethereum) and apply that knowledge to simplify cross-chain operations Required Skills and Experience: 5+ years of software engineering experience, with demonstrated ownership of production services in a servi

REMOTEmongodbredisaws
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C
Coinbase
📍 - USA• Full-time• Remote• From $186.1K/yr
1mo ago

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . Senior Software Engineer, Backend - Platform (Tokens & Wrapped Assets) We're hiring a Senior Software Engineer to join the Tokens & Wrapped Assets team within the Platform organization. This team builds and operates the platform that issues, wraps, and transforms every asset at Coinbase, including flagship wrapped assets like cbBTC, spanning Ethereum, Base, and Solana. You'll own complex projects end-to-end, from smart contract through APIs and production rollout, designing and operating the Go services that mint, burn, bridge, and reconcile wrapped assets across chains. What you'll do: Own end-to-end delivery of complex token and wrapped asset initiatives, from smart contract deployment through API design, SLOs, and production rollout across multiple chains. Build and operate the Go services and smart contracts that mint, burn, bridge, and reconcile wrapped assets, ensuring correctness across on-chain and off-chain systems. Drive improvements to the asset transformation and migration pipeline, making it dramatically faster and safer to launch, upgrade, and migrate tokens at scale. Partner across Trading, Custody, USDC, Compliance, and the broader crypto stack to ship customer- and revenue-impacting work that advances onchain innovation. Lead on-call ownership for team services, building observability, runbooks, and operational improvements that keep T

REMOTEawsaigo
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C
Coinbase
📍 - USA• Full-time• Remote• From $218K/yr
1mo ago

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . Coinbase is building prediction markets as part of the Everything Exchange, letting millions of users trade on the outcomes of real-world events across sports, politics, crypto, and culture. We're building the full regulated stack in-house: our own exchange, clearing, and settlement infrastructure. As a Staff Software Engineer on the Prediction Markets team , you'll design and own the core backend systems that power market discovery, best-in-class trading experiences, order management, market resolution, and settlement. It's a rare chance to build market infrastructure from the ground up, with the ownership of a startup and the reach of Coinbase. What you’ll do: Own the design, development, and reliability of backend systems that power order management, trade matching, settlement, and market resolution for prediction markets Architect distributed systems that enforce strict correctness guarantees across clearing, payout, and position management workflows Drive the technical strategy for migrating from third-party venue participation to a fully Coinbase-operated exchange and clearing platform Lead cross-functional collaboration with Product, Compliance, and Risk teams to ensure the platform meets regulatory requirements and launches with confidence Shape engineering standards and practices across the Prediction Markets team, setting a high bar for code quality, system

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L
Lyft
📍 Toronto• Full-time• From C$136K/yr
1mo ago

At Lyft, our purpose is to serve and connect. We aim to achieve this by cultivating a work environment where all team members belong and have the opportunity to thrive. Our mission depends on having a digital representation of the physical world - a map with all routing related (real-time) information. This is what makes Lyft different from many products: our products don’t just facilitate online interactions, they facilitate dynamic, real-world ones. Without mapping services, none of these real world interactions between people and transport can happen. We are hiring a Senior Software Engineer to join our Pickup, Places and Search team within the Mapping organization that is responsible for building, enhancing and maintaining the Rider and Driver product for the Pickup/Drop off Experience. This team supports the backbone of Lyft’s search system, supporting millions of rides by helping our riders and drivers connect and reach their destination. Our focus is to ensure the pickup/dropoff experience is seamless by enhancing guidance and routing as well as the rider experience. Additionally the team uses map data and other signals to create new product experiences in collaboration with teams across Lyft. This team has a history of enabling rich and creative features that directly influence the product for all of our users. We constantly innovate and incorporate cutting-edge technologies to make the lives of our community more enriched. In this role, you'll collaborate with other engineering teams, product, data science, analytics, and operations on programs that empower us to iterate quickly, delighting our passengers and drivers with rideshare focused mapping experiences. Responsibilities: Drive high-impact projects and innovate new solutions to provide the best customer experiences Lead backend and cross functional projects to achieve long term goals as well as deliver short term roadmaps Lead large features from idea to successful execution and launch Own systems and

pythonsqlaws
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S
1mo ago

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team Risk Engineering builds the systems that protect Stripe from fraud, credit losses, and regulatory risk across user onboarding, compliance, financial crimes, and identity verification. Financial Crimes Engineering builds the systems and controls that let Stripe safely onboard businesses in emerging and regulated industries while keeping Stripe in compliance with sanctions law, anti-money-laundering rules, and financial partner requirements. We keep known bad actors off Stripe, find new through ongoing detection, and build AI-augmented tooling that helps expert reviewers resolve cases quickly and accurately. We operate at scale, screening every user, enforcing jurisdictional restrictions across money movement in real time, and automating signal acquisition and synthesis into investigation workflows. We're now re-architecting our screening platform to make it safe and easy for new Stripe products to launch with the right financial crimes controls, to express richer policy as code, and to serve as a multi-tenant Risk Platform offering across Stripe's products and subsidiaries. What you'll do As a Staff Engineer on Financial Crimes Engineering, you'll own technical direction across our screening, detection, and review systems. You'll design infrastructure that balances screening latency with accuracy, build the systems that surface emerging risk and collect information to resolve it, and ensure investigators have the tooling they need.

javarestai
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Who We Are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies — from the world's largest enterprises to the most ambitious startups — use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the Team The Core Change Management group is responsible for the systems that let every Stripe engineer ship code, configuration, and infrastructure changes safely and at high velocity. You will be embedded primarily on the Service Deployments team — the owners of Stripe's end-to-end code deployment platform — with regular collaboration with the Resource Automation and Feature Deployments teams. What Makes This Role Compelling You own the foundation of how Stripe ships software. The deployment platform sits in the critical path of every engineer's workflow at Stripe. The decisions you make affect thousands of deploys per day across hundreds of services, directly determining how fast and safely Stripe's product evolves. Technically rich, architecturally active. The team is executing several concurrent platform transformations: containerizing host-based services at scale, adding intelligent multi-service deploy pipelines, extending real-time anomaly detection to earlier stages of traffic shifts, and rebuilding deployment event infrastructure on top of a durable message bus. This is not maintenance work — the architecture is in motion. Broad surface area, real ownership. You will span the full stack from container scheduling and deployment orchestration business logic to the developer-facing internal platform UI. The problems are multi-layered: reliability, developer experience, performance, and safety all at once. Your judgment prevents incidents.

awsazurekubernetes
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S
Stripe
📍 South San Francisco• Full-time• $212K – $318K/yr
1mo ago

Who we are About Stripe Stripe, LLC. is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. What you’ll do Responsibilities Design state-of-the-art ML models and large-scale ML systems for underwriting and portfolio management for Stripe Capital based on ML principles, domain knowledge, risk, regulatory and engineering constraints. Design systems to speed up the time from idea to deployment of new models. Experiment and iterate on ML models (using tools including PyTorch and TensorFlow) to achieve key business goals and drive efficiency. Develop pipelines and automated processes to train and evaluate models in offline and online environments. Integrate ML models into production systems and ensure their scalability and reliability. Collaborate with product and strategy partners to propose, prioritize, and implement new product features. Engage with the latest developments in ML/AI and take calculated risks in transforming innovative ML ideas into productionized solutions. Who you are Minimum requirements Must have a Bachelor's degree or foreign equivalent in Computer Science, Machine Learning, Mathematics, Physics, Statistics, or a related field, plus two (2) years of experience in Building and shipping ML systems in production. Must have two (2) years of experience in each of the following: ML algorithms and model architectures; Designing, training and evaluating machine learning models; Productionizing and deploying machine learning models at scale; Orchestrating data pipelines and leveraging large-s

machine learningaigo
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Integration Reliability Engineer, Technical Operations About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team APAC Payins TechOps is a newly formed team based in Singapore. Our charter is to improve the health and resilience of our payment acquiring volume, making it easier for Stripe to build and operate the integrations that support hundreds of billions of dollars in payments annually. Our team partners closely with payments and platform engineering teams to assess systems or processes that create high operational workloads, then develops durable solutions via code, tooling, data, and process improvements. We are responsible for the financial data quality of key systems at Stripe, ensuring that data is quarantined without impacting downstream systems while implementing the right changes upstream to prevent recurring issues. The team's work has a direct impact on Stripe's ability to expand into new markets and offer more sophisticated payment features to merchants. What you’ll do Responsibilities Scope and lead technical initiatives end-to-end: identify problems worth solving, propose the right solution approach, and deliver on that solution — not just execute on a pre-defined plan. Investigate problems in systems by tracing problems through Stripe’s stack. You’ll examine code, write SQL queries, read logs, and inspect data pipelines to understand system behavior, then make changes to address. Examine updates being made by Stripe’s financial partners to understand impact, and make the changes within Strip

sqlgitrest
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About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Threat Intelligence team protects OpenAI’s technology, people, research, and infrastructure by proactively identifying and disrupting adversaries who seek to compromise our systems or misuse our models. We investigate sophisticated threats, build tooling to scale and augment analysis, and deliver intelligence that shapes security strategy and equips leadership with timely, risk-aware insights. We combine technical depth, investigative rigor, and strong cross-functional partnerships to uncover threats and drive impact across OpenAI’s security and research organizations. About the Role As a Technical Threat Investigator at OpenAI, you will help protect the company from sophisticated adversaries targeting OpenAI and the broader ecosystem, as well as those attempting to misuse our models in support of cyber operations. This is a deeply investigative role. You will independently conduct complex, end-to-end investigations into capable threat actors to understand their behavior, infrastructure, emerging techniques, and how AI is integrated into their workflows. You’ll use these insights to proactively identify malicious activity and drive detection, disruption, enforcement, and safety improvements across the company. You’ll translate your investigative findings into durable solutions that scale impact. You’ll build and own lightweight tooling, automate where it matters, and create AI-assisted workflows to make investigations faster, more repeatable, and more effective over time. In this role, you will: Conduct deep, end-to-end investigations into sophisticated threat actors interacting with OpenAI’s models, products, and broader ecosystem. Think like an adversary — model attacker behavior, anticipate misuse patterns, and proactively hunt for, identify, and disrupt malicious activity. Leverage internal telemetry, OSINT, vendor data, a

awsrestai
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O
OpenAI
📍 San Francisco• Full-time
1mo ago

About the Team The Support Automation team at OpenAI scales the organization by applying cutting-edge AI models to real-world challenges, automating and enhancing work across the organization. From customer operations to engineering, we develop an ecosystem of automation products that empower our colleagues and drive impact. We're passionate about crafting products that serve those around us, blending rapid prototyping with a focus on long-term quality and reliability. By creating reusable solutions, we create patterns that can be applied across diverse domains within OpenAI. TLDR: this team leverages OpenAI technology to improve OpenAI, and you’ll have the opportunity to leverage the full extent of our tech (both public and pre-released) to accomplish this mission. About the Role We’re looking for a Backend Software Engineer with experience working in ML/LLM-heavy domains to help to design and build an evals infrastructure that measures the quality of OpenAI’s support automation. This is a deeply technical and highly cross-functional role where you’ll build robust systems and backend services that serve as the foundation for how knowledge is created, accessed, and applied across OpenAI. The role will especially focus on working closely with Data Science and Research partners to design and build evals at scale. In this role, you will: Design eval pipelines that are reliable, reproducible, and extendable Build the infrastructure for continuous eval monitoring frameworks (regression/drift monitoring, building robust golden datasets) along with feedback loops that ultimately strengthen support automation Design, build, and maintain backend services and APIs to support intelligent automation and knowledge systems Integrate and structure data across internal platforms, transforming it into formats optimized for use by downstream systems and AI workflows. Collaborate closely with data, research, and engineering teams to integrate OpenAI models into high-leverage workflows

pythonawsrest
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About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Threat Intelligence team protects OpenAI’s technology, people, research, and infrastructure by proactively identifying and disrupting adversaries who seek to compromise our systems or misuse our models. We investigate sophisticated threats, build tooling to scale and augment analysis, and deliver intelligence that shapes security strategy and equips leadership with timely, risk-aware insights. We combine technical depth, investigative rigor, and strong cross-functional partnerships to uncover threats and drive impact across OpenAI’s security and research organizations. About the Role As a Technical Threat Investigator at OpenAI, you will help protect the company from sophisticated adversaries targeting OpenAI and the broader ecosystem, as well as those attempting to misuse our models in support of cyber operations. This is a deeply investigative role. You will independently conduct complex, end-to-end investigations into capable threat actors to understand their behavior, infrastructure, emerging techniques, and how AI is integrated into their workflows. You’ll use these insights to proactively identify malicious activity and drive detection, disruption, enforcement, and safety improvements across the company. You’ll translate your investigative findings into durable solutions that scale impact. You’ll build and own lightweight tooling, automate where it matters, and create AI-assisted workflows to make investigations faster, more repeatable, and more effective over time. In this role, you will: Conduct deep, end-to-end investigations into sophisticated threat actors interacting with OpenAI’s models, products, and broader ecosystem. Think like an adversary — model attacker behavior, anticipate misuse patterns, and proactively hunt for, identify, and disrupt malicious activity. Leverage internal telemetry, OSINT, vendor data, a

awsrestai
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S
1mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Senior Software Engineer, Warehouse UX About Snowflake At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You do not just use tools; you bring an innate curiosity and treat AI as a high-trust collaborator that is core to how you solve problems, deepen your technical leverage, and accelerate your impact. We look for low-ego individuals who thrive in dynamic, fast-moving environments and operate with an experimental mindset, rapidly testing emerging capabilities to uncover simpler, more powerful ways to deliver results. At Snowflake, your role is not just to execute within a function, but to help redefine how world-class engineering teams build, operate, and innovate. About the Role We are hiring a Senior Software Engineer to join the Warehouse UX pod at Snowflake. This team owns critical warehouse capabilities spanning features, billing, and usability across the warehouse experience. Warehouses are one of the most mission-critical parts of Snowflake’s platform and a major revenue driver for the company, making this an opportunity to work on high-impact systems at significant scale. Despite the UX pod name, this is not a fron

aigorust
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At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. The Mission: Building the Data Foundations for AI We are the Snowflake Interoperable Foundations organization - the foundational layer that powers Snowflake’s AI, Analytics and Data Engineering capabilities. We lead innovations across open table formats such as Apache Iceberg, helping customers build peta-byte scale multi-cloud data lakes on Snowflake. We deliver core Metadata capabilities that power Snowflake’s industry-leading performance, AI, governance and platform features. We are embarking on a 0->1 redesign of our core systems across Interoperable Foundations. While we already manage exabyte-scale data supporting Snowflake’s AI capabilities, the next frontier is providing the foundational data layer that accelerates agentic innovation in an open, multi-format data world, You will be setting the technical vision across our investments in metadata platforms, Apache Iceberg and AI-ready storage. Your Impact: From Redesign to Reality 0->1 Architectural Leadership: Lead the ground-up redesign of our core Metadata systems, influencing the transaction frameworks that power query, DML, and AI-driven data interactions in addition to extending our lead on platform capabilities such as Zero Copy Cloning and Cross-Region / Cross-Cloud Replication. Iceberg Innovation: Drive

aigorust
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PE
Private Employer
📍 Remote• Full-time• Remote
1mo ago

At Curai, we believe that access to high-quality healthcare is a fundamental human right, not a privilege. Our mission is to radically transform healthcare delivery by harnessing the power of artificial intelligence and clinical expertise to make care more affordable, accessible, and effective for everyone. Patients interact with advanced AI systems at every step of their care and follow-up. Licensed physicians review each case with the patient for the clinical decision in our integrated virtual clinic. We ground our approach in rigorous research, continuous learning, and a deep commitment to clinical integrity. We focus on making a real impact: improving health outcomes, expanding access to care, and setting new standards for what trustworthy, patient-centered healthcare is. Read some of our latest publications.

REMOTEaigorust
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