TPMs at Datadog see the problems hiding between teams, engineer away the work that shouldn’t require humans, and drive the company’s most technically complex and consequential bets to completion. Technical Program Management at Datadog operates at the intersection of engineering depth and organizational reach by driving high priority, cross-functional programs that are too complex and consequential for any single team to own. We partner with engineering on solving deeply technical problems at scale by connecting the people, decisions, and context to move Datadog's most important work forward. We build the systems and automation that make entire classes of program work self-executing. We are in the architecture conversation early, earning trust through technical judgment. We use AI to surface risks earlier, accelerate program execution plans, and find cross-team patterns that would otherwise stay hidden. The faster teams move, the more essential it is to have someone who can operate across them. At Datadog, we place value in our office culture - the relationships that it builds, the creativity it brings to the table, and the collaboration of being together. We operate as a hybrid workplace to ensure our employees can create a work-life harmony that best fits them. What We Expect: These are the expectations we hold for every TPM at Datadog. Technical depth, product domain expertise, and AI systems literacy; knowing how AI solutions work, where they fail, and the scope and impact of those failures. AI brings more complexity into the picture - the technical bar is higher, not lower. Build the systems that reduce the need for coordination Identify what matters before anyone asks, and automate the rest Engineer program lifecycles end-to-end See what no single team can see and own the solution Drive the company's most technically complex and consequential bets through cross-functional agreement, organizational visibility, and influence Build AI powered automation tools and

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Principal Technical Program Manager, Science, Imaging

Biohub

📍 Redwood City• Full-time• Hybrid• $214K – $268K/yr

1mo ago

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team Through our multi-dimensional imaging program, we build imaging tools that capture life across scales — from single proteins to whole organisms — revealing how proteins and cells function, communicate, and assemble into living systems. These observations are laying the groundwork for a new generation of AI models that can predict cellular behavior and guide the development of better treatments for widespread diseases. You can learn more about our work here . Our work brings together three powerhouse universities - Stanford, UC Berkeley, and UC San Francisco - into a single collaborative technology and discovery engine. Our Vision Pursue large scientific challenges that cannot be pursued in conventional environments Enable individual investigators to pursue their riskiest and most innovative ideas Facilitate research by scientists and clinicians at our home institutions and beyond We are a team of passionate individuals powered by technology, guided by scientific research, and driven by collaboration, working toward a mission to cure or prevent all disease. The Opportunity Biohub is seeking an experienced Technical Project Manager to support the VP of Imaging in leading cross-functional teams to plan, execute, and deliver ambitious imaging science and technology projects. The ideal candidate will combine strong technical knowledge with exceptional project management skills to guide complex initiatives from conception to completion. This is ideal for a TPM who takes pride in discipli

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