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Senior Applied Research Engineer Jobs

7,101 active opportunities · Updated for October 2026

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Explore current senior applied research engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

H
1mo ago

Become a part of our caring community Most AI engineering jobs are a thin wrapper around a model API. This role is different. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to the source document, and route ambiguous cases to human experts for review. Our users make decisions that impact real healthcare outcomes, so “good enough” is not good enough. Building AI systems that are accurate, reliable, auditable, and scalable is at the core of this role. As a Senior AI Applied Engineer, you will design, build, deploy, and operate production AI systems used at scale within one of the largest health insurers in the United States. You will own solutions end-to-end, from user experience and APIs to model orchestration, evaluation frameworks, infrastructure, and production operations. Why Join Us Build production AI systems where LLMs are in the critical path, not just demos or proofs of concept. Work on extraction, retrieval, agentic workflows, and human-review systems that process real healthcare data at scale. Own projects end-to-end across frontend, backend, AI orchestration, infrastructure, deployment, and operations. Solve challenging problems around accuracy, explainability, traceability, and reliability in regulated environments. Ship quickly in a small, high-impact team that embraces AI-assisted development and rigorous quality standards. Build systems that continuously improve through expert feedback, evaluations, and human-in-the-loop workflows. Key Responsibilities Design, develop, and deploy full-stack AI-powered application

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F
1mo ago

About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. Senior Software Engineer: Applied AI Every day, thousands of shipments cross borders, change hands, and hit unexpected problems. For decades, fixing those problems meant phone calls, emails, and humans heroically firefighting. We think that's about to change completely. We've been building AI agents that spot trouble before it happens, reroute shipments, and keep goods moving—with our team of experts in the loop where it counts. The early results have been jaw-dropping. We're now going all in on a future where supply chains run themselves, and we're looking for the people who want to build that future with us. This isn't a role where you join a team and pick up tickets. You'll find the highest-leverage problems, design the solutions, and ship them to operators moving freight across 112 countries. If that sounds like your idea of a good time, read on. What You'll Do You'll build th

typescriptagileai
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F
1mo ago

About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. Senior Software Engineer: Applied AI Every day, thousands of shipments cross borders, change hands, and hit unexpected problems. For decades, fixing those problems meant phone calls, emails, and humans heroically firefighting. We think that's about to change completely. We've been building AI agents that spot trouble before it happens, reroute shipments, and keep goods moving—with our team of experts in the loop where it counts. The early results have been jaw-dropping. We're now going all in on a future where supply chains run themselves, and we're looking for the people who want to build that future with us. This isn't a role where you join a team and pick up tickets. You'll find the highest-leverage problems, design the solutions, and ship them to operators moving freight across 112 countries. If that sounds like your idea of a good time, read on. What You'll Do You'll build the cutting-edge agents and AI-powered applications that make Flexport's operations smarter, faster, and increasingly autonomous. That means: Designing and shipping end-to-end AI agents that handle real logistics work—customs compliance, document processing, exception management, and more. C

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For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. We are looking for a Senior Product Manager to join our Applied AI organization at Smartsheet. You'll own the roadmap for specialized AI agents and evaluation infrastructure, ship complex agent capabilities end-to-end, and define the standards that enable teams across the company to build agents successfully. You'll report to our Director of Product Management for Applied AI located in our Bellevue, WA office, or you may work remotely from anywhere in the US where Smartsheet is a registered employer. You Will: Own the strategy, roadmap, and execution for specialized AI agents and evaluation infrastructure Ship large, technically complex agent capabilities end-to-end with with a high degree of autonomy Define agentic development standards that enable teams beyond your own to build high-quality agents Mentor and develop junior PMs on your team Build strong cross-functional partnerships with engineering, design, and data science to drive alignment and move work forward Support other duties as assigned You Have: 8-10+ years of product management experience with technically complex platforms Fluency in AI/ML concepts -model evaluation, agent architectures, RAG, prompt engineering, quality measurement Track record of shipping enterprise software from inception to launch Experience building or managing evaluation and quality infrastructure for AI or ML systems (strongly preferred) Comfort operating in high-ambiguity environments with significant autonomy Exceptional communication skills and the ability to influence without auth

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For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. About the Role The AI Platform Engineering team is looking for a highly motivated and talented engineer who are passionate about continuous learning and excited to grow in a fast-paced, innovative environment. We are an agile team that operates iteratively, focused on building high-quality software and adhering to rigorous operational best practices across complex, cross-functional distributed systems. This full-time position reports to a Software Engineering Manager and can be located in our Bellevue, WA office, or you may work remotely from anywhere in the US where Smartsheet is a registered employer. What You'll Do Build the AI Platform Foundation : Lead the design and ownership of the core infrastructure that serves as the backbone for all Smartsheet AI experiences. Focus on building a robust, multi-tenant environment that reduces friction for internal teams, allowing them to deploy reliable and scalable AI features with ease. Standardize the AI Developer Path : Architect high-level abstractions and "Golden Path" APIs that democratize AI development across Smartsheet. By insulating product teams from infrastructure complexity, you will enable them to ship intelligent features with high velocity while guaranteeing safety and consistency at scale. Engineer AI Trust & Safety Systems : Establish the mission-critical monitoring and quality assurance layers that protect Smartsheet customers. By creating rigorous evaluation pipelines, you will ensure every AI-driven feature meets the high bar for safety, data privacy, a

REMOTEpythonvueaws
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NVIDIA has continuously reinvented itself over two decades. Our invention of the GPU in 1999 sparked the growth of the PC gaming market, redefined modern computer graphics, and revolutionized parallel computing. More recently, GPU deep learning ignited modern AI — the next era of computing. NVIDIA is a “learning machine” that constantly evolves by adapting to new opportunities that are hard to solve, that only we can address, and that matter to the world. This is our life’s work, to amplify human creativity and intelligence. Make the choice to join us today. Design-for-Test Engineering at NVIDIA works on groundbreaking innovations involving crafting creative solutions for DFT architecture, verification and post-silicon validation on some of the industry's most complex semiconductor chips. What you'll be doing: As a senior member in our team, you will work with pre-silicon and post-silicon data analytics - visualization, insights and modeling. Design and uphold sturdy data pipelines and ETL processes for the ingestion and processing of DFX Engineering data from various origins Lead engineering efforts by collaborating with cross-functional teams (execution, analytics, data science, product) to define data requirements and ensure data quality and consistency You will work on hard-to-solve problems in the Design For Test space which will involve application of algorithm design, using statistical tools to analyze and interpret complex datasets and explorations using Applied AI methods. In addition, you will help develop and deploy DFT methodologies for our next generation products using Gen AI solutions. You will also help mentor junior engineers on test designs and trade-offs including cost and quality. What we need to see: BSEE (or equivalent experience) with 5+, MSEE with 3+, or PhD wi

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At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Our Solution Engineering organization is seeking an AI Specialist who can provide hands-on expertise and support while working with technical decision makers and data scientists to design and architect AI solutions built on the Snowflake AI Data Cloud. This is a strategic role that works closely with cross-functional teams, including product, engineering, and the broader field organization to ensure successful execution and customer adoption of Snowflake’s AI & ML solutions. IN THIS ROLE YOU WILL GET TO: Be the technical expert in the room that positions Snowflake’s AI and ML features and value to technical stakeholders at Snowflake’s customers across the Americas. Partner with Snowflake account team teams and customer champions to scope and drive POCs to success and technical wins that prove the value of Snowflake’s capabilities, including executive readouts and business value cases. Collaborate with Snowflake’s product and engineering teams to influence Snowflake’s AI and ML roadmaps based on customer feedback. Publish content that helps the team and company scale beyond your individual efforts, like blog posts, presentations at conferences, or technical collateral like notebooks and demos. Influence, tailor and maintain Sales Engineering AI and ML selling assets, inc

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J
Justworks
📍 Mexico City• Full-time• MX$1.7M – MX$2.2M/yr
1mo ago

Who We Are At Justworks, you’ll enjoy a welcoming and casual environment, great benefits, wellness program offerings, company retreats, and the ability to interact with and learn from leaders in the startup community. We work hard and care about our most prized asset - our people. We’re helping businesses get off the ground by enabling them to focus on running their business. We solve HR issues. We’re data-driven and never stop iterating. If you’d like to work in a supportive, entrepreneurial environment, are interested in building something meaningful and having fun while doing it, we’d love to hear from you. We're united by shared goals and shared motivations at Justworks. These are best summed up in our company values, which are reflected in our product and in our team. Our Values If this sounds like you, you’ll fit right in. Who You Are You are self-driven and like to work with others to remove roadblocks. You are curious and love to explore and learn new technologies. You have demonstrated the ability to build, deploy, and maintain large-scale, complex applications. You care more about solutions and impacting the customer experience than using a particular tool or framework. About the role: You will join a small, highly autonomous cross-functional team to build AI agents that fundamentally transform how operations work at scale. Instead of writing bespoke software for every workflow, we are developing an agent platform that can read operational knowledge, reason about it in context, and execute tasks end-to-end. This approach allows us to scale complexity through knowledge and reasoning, rather than simply through code. This is an opportunity to join a foundational team, which currently consists of fewer than five engineers. The work spans critical areas including LLM-powered agent design, robust backend service architecture, tool and integration development, and sophisticated knowledge infrastructure. We are seeking a Senior Software Engineer with a strong pas

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J
Justworks
📍 International• Full-time• Remote• £132K – £170K/yr
1mo ago

Who We Are At Justworks, you’ll enjoy a welcoming and casual environment, great benefits, wellness program offerings, company retreats, and the ability to interact with and learn from leaders in the startup community. We work hard and care about our most prized asset - our people. We’re helping businesses get off the ground by enabling them to focus on running their business. We solve HR issues. We’re data-driven and never stop iterating. If you’d like to work in a supportive, entrepreneurial environment, are interested in building something meaningful and having fun while doing it, we’d love to hear from you. We're united by shared goals and shared motivations at Justworks. These are best summed up in our company values, which are reflected in our product and in our team. Our Values If this sounds like you, you’ll fit right in. Who You Are You are self-driven and like to work with others to remove roadblocks. You are curious and love to explore and learn new technologies. You have demonstrated the ability to build, deploy, and maintain large-scale, complex applications. You care more about solutions and impacting the customer experience than using a particular tool or framework. About the role: You will join a small, highly autonomous cross-functional team to build AI agents that fundamentally transform how operations work at scale. Instead of writing bespoke software for every workflow, we are developing an agent platform that can read operational knowledge, reason about it in context, and execute tasks end-to-end. This approach allows us to scale complexity through knowledge and reasoning, rather than simply through code. This is an opportunity to join a foundational team, which currently consists of fewer than five engineers. The work spans critical areas including LLM-powered agent design, robust backend service architecture, tool and integration development, and sophisticated knowledge infrastructure. We are seeking a Senior Software Engineer with a strong pas

REMOTEjavascriptpythonjava
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J
Justworks
📍 International• Full-time• Remote• $111K – $143K/yr
1mo ago

Who We Are At Justworks, you’ll enjoy a welcoming and casual environment, great benefits, wellness program offerings, company retreats, and the ability to interact with and learn from leaders in the startup community. We work hard and care about our most prized asset - our people. We’re helping businesses get off the ground by enabling them to focus on running their business. We solve HR issues. We’re data-driven and never stop iterating. If you’d like to work in a supportive, entrepreneurial environment, are interested in building something meaningful and having fun while doing it, we’d love to hear from you. We're united by shared goals and shared motivations at Justworks. These are best summed up in our company values, which are reflected in our product and in our team. Our Values If this sounds like you, you’ll fit right in. Who You Are You are self-driven and like to work with others to remove roadblocks. You are curious and love to explore and learn new technologies. You have demonstrated the ability to build, deploy, and maintain large-scale, complex applications. You care more about solutions and impacting the customer experience than using a particular tool or framework. About the role: You will join a small, highly autonomous cross-functional team to build AI agents that fundamentally transform how operations work at scale. Instead of writing bespoke software for every workflow, we are developing an agent platform that can read operational knowledge, reason about it in context, and execute tasks end-to-end. This approach allows us to scale complexity through knowledge and reasoning, rather than simply through code. This is an opportunity to join a foundational team, which currently consists of fewer than five engineers. The work spans critical areas including LLM-powered agent design, robust backend service architecture, tool and integration development, and sophisticated knowledge infrastructure. We are seeking a Senior Software Engineer with a strong pas

REMOTEjavascriptpythonjava
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J
Justworks
📍 International• Full-time• Remote• €143K – €184K/yr
1mo ago

Who We Are At Justworks, you’ll enjoy a welcoming and casual environment, great benefits, wellness program offerings, company retreats, and the ability to interact with and learn from leaders in the startup community. We work hard and care about our most prized asset - our people. We’re helping businesses get off the ground by enabling them to focus on running their business. We solve HR issues. We’re data-driven and never stop iterating. If you’d like to work in a supportive, entrepreneurial environment, are interested in building something meaningful and having fun while doing it, we’d love to hear from you. We're united by shared goals and shared motivations at Justworks. These are best summed up in our company values, which are reflected in our product and in our team. Our Values If this sounds like you, you’ll fit right in. Who You Are You are self-driven and like to work with others to remove roadblocks. You are curious and love to explore and learn new technologies. You have demonstrated the ability to build, deploy, and maintain large-scale, complex applications. You care more about solutions and impacting the customer experience than using a particular tool or framework. About the role: You will join a small, highly autonomous cross-functional team to build AI agents that fundamentally transform how operations work at scale. Instead of writing bespoke software for every workflow, we are developing an agent platform that can read operational knowledge, reason about it in context, and execute tasks end-to-end. This approach allows us to scale complexity through knowledge and reasoning, rather than simply through code. This is an opportunity to join a foundational team, which currently consists of fewer than five engineers. The work spans critical areas including LLM-powered agent design, robust backend service architecture, tool and integration development, and sophisticated knowledge infrastructure. We are seeking a Senior Software Engineer with a strong pas

REMOTEjavascriptpythonjava
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J
Justworks
📍 Toronto• Full-time• C$188K – C$242K/yr
1mo ago

Who We Are At Justworks, you’ll enjoy a welcoming and casual environment, great benefits, wellness program offerings, company retreats, and the ability to interact with and learn from leaders in the startup community. We work hard and care about our most prized asset - our people. We’re helping businesses get off the ground by enabling them to focus on running their business. We solve HR issues. We’re data-driven and never stop iterating. If you’d like to work in a supportive, entrepreneurial environment, are interested in building something meaningful and having fun while doing it, we’d love to hear from you. We're united by shared goals and shared motivations at Justworks. These are best summed up in our company values, which are reflected in our product and in our team. Our Values If this sounds like you, you’ll fit right in. Who You Are You are self-driven and like to work with others to remove roadblocks. You are curious and love to explore and learn new technologies. You have demonstrated the ability to build, deploy, and maintain large-scale, complex applications. You care more about solutions and impacting the customer experience than using a particular tool or framework. About the role: You will join a small, highly autonomous cross-functional team to build AI agents that fundamentally transform how operations work at scale. Instead of writing bespoke software for every workflow, we are developing an agent platform that can read operational knowledge, reason about it in context, and execute tasks end-to-end. This approach allows us to scale complexity through knowledge and reasoning, rather than simply through code. This is an opportunity to join a foundational team, which currently consists of fewer than five engineers. The work spans critical areas including LLM-powered agent design, robust backend service architecture, tool and integration development, and sophisticated knowledge infrastructure. We are seeking a Senior Software Engineer with a strong pas

javascriptpythonjava
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At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We seek a highly specialised technical Senior Security Architect (SA) who practices security with an obsession for helping customers design and implement the best security mechanisms, particularly those that would relate to the Snowflake AI & Data Cloud. At Snowflake, Security Architects are passionate about security, often involving tremendous technology challenges that require no simple solutions. Success requires working collaboratively with a broad range of people inside and outside the company. Operating out of our APJ Field CTO Office , you will serve as our primary South Korean Security expert, who will be a cloud compliance evangelist, technical architect, and hands-on practitioner. This specialized role bridges the gap between global cloud data architecture and South Korea’s rigorous, localized regulatory frameworks, specifically the Cloud Security Assurance Program (CSAP) and the Korea Financial Services Institute (K-FSI) Safety Evaluation. IN THIS ROLE YOU WILL GET TO: Help to scope security related feature enhancements on behalf of customers to work with Product Management and Engineering on ways to enhance requirements for the local market. Help drive Snowflake adoption by advising customers and engineering teams on how to build secure Korea-compliant Data

pythonsqlaws
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At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Our Sales Engineering organization is seeking an AI Specialist who can provide hands-on expertise and support while working with technical decision makers and data scientists to design and architect AI solutions built on the Snowflake AI Data Cloud. This is a strategic role that works closely with cross-functional teams, including product, engineering, and the broader field organization to ensure successful execution and customer adoption of Snowflake’s AI & ML solutions. IN THIS ROLE YOU WILL GET TO: Be the technical expert in the room that positions Snowflake’s AI and ML features and value to technical stakeholders at Snowflake’s customers across the APJ region. Partner with Snowflake account team teams and customer champions to scope and drive POCs to success and technical wins that prove the value of Snowflake’s capabilities, including executive readouts and business value cases. Collaborate with Snowflake’s product and engineering teams to influence Snowflake’s AI and ML roadmaps based on customer feedback. Publish content that helps the team and company scale beyond your individual efforts, like blog posts, presentations at conferences, or technical collateral like notebooks and demos. Influence, tailor and maintain Sales Engineering AI and ML selling assets, incl

pythonawsazure
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