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Staff Bioinformatics Scientist Oncology Mrd Algorithm Development Jobs

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You’ll shape the future of a business‑critical platform as the technical lead across both product engineering and cloud infrastructure. You’ll modernize a mature .NET application running on AWS today, while steering its evolution toward a cloud‑native, React/Node.js, AI‑enabled architecture. If you enjoy owning architecture end‑to‑end, from backend and frontend through CI/CD, DevOps, and AWS infrastructure, this role gives you real influence at Staff Engineer level and the opportunity to set engineering standards that others follow. You’ll spend your time leading complex .NET and React features, designing scalable AWS infrastructure with Infrastructure as Code, and building automation that makes releases fast, safe, and repeatable. You’ll work on performance, reliability, and modernization in equal measure—fixing what’s slowing the platform down today and designing what it will look like in the next generation. Here’s a breakdown of what you’ll do (not all of it, just the important stuff) Lead the architecture and development of enterprise .NET services and APIs that power a business‑critical platform. Design and operate AWS infrastructure (using AWS CDK in TypeScript) to support secure, scalable, multi‑environment deployments. Build and optimize CI/CD pipelines (AWS CodePipeline, CodeBuild, Windows build agents) to make shipping .NET and React changes fast and reliable. Drive modernization initiatives across the stack, including clean architecture, refactoring legacy components, and reducing technical debt. Design and tune PostgreSQL and MSSQL database solutions for performance, scalability, and reliability. Mentor engineers and influence engineering practices across teams, raising the bar on cloud, DevOps, and software design. These are the essentials you’ll need to get an interview Significant experience (typically 8+ years) delivering and operating scalable enterprise software, owning both application code and cloud infrastructure. Deep hands‑on expertise with C

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Scale AI
📍 San Francisco• Full-time• From $252K/yr
16 days ago

The Public Sector software engineers (SWEs) create the core product building blocks forward-deployed teams use to develop agentic capabilities that function across multiple domains. SWEs responsibilities include building the systems required to ingest and process federal datasets to support real-time decision-making in contested environments. We develop novel agentic enabling capabilities that includes: Create multi-layered guardrails around agents Optimize data retrieval for agents Orchestrate fleets of asynchronous agents Automatically alerts users to deviations in data Illustrating how an agent reached a decision As a Staff Software Engineer, you will orchestrate the implementation of vertical features and horizontal capabilities to include mentoring other engineers on defining requirements with stakeholders and communication tradeoffs of technical implementations on feature and capabilities until they are accepted by the stakeholders. You will: Orchestrate feature implementation across the Federal engineering team to ensure architectural consistency. Define technical strategy for agentic guardrails, explainability, and fleet orchestration. Ensure system reliability and performance across multiple security classifications and network types. Mentor engineers in the process of defining requirements with stakeholders and gathering acceptance. Communicate high-level technical trade-offs and implementation strategies to senior government stakeholders and Scale C-Suite members. Influence the long-term product strategy and technical roadmap for the Federal business unit. Consult on the architecture of AI-powered solutions for large-scale federal contracts. Ideally you will have: Full Stack Development: Proficiency in front-end, back-end development and infrastructure, including experience with modern web development frameworks, programming languages, and databases Cloud-Native Technologies: Familiarity with cloud platforms (e.g., AWS, Azure, GCP) and experience in

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Scale AI
📍 San Francisco• Full-time• From $252K/yr
16 days ago

Software is eating the world, but AI is eating software. We live in unprecedented times – AI has the potential to exponentially augment human intelligence. Every person will have a personal tutor, coach, assistant, personal shopper, travel guide, and therapist throughout life. As the world adjusts to this new reality, leading platform companies are scrambling to build LLMs at billion scale, while large enterprises figure out how to add it to their products. To make them safe, aligned and actually useful, these models need human evaluation and reinforcement learning through human feedback (RLHF) during pre-training, fine-tuning, and production evaluations. This is the main innovation that’s enabled ChatGPT to get such a large headstart among competition. At Scale, our products include the Generative AI Data Engine, SGP, Donovan, and others that power the most advanced LLMs and generative models in the world through world-class RLHF, human data generation, model evaluation, safety, and alignment. The data we are producing is some of the most important work for how humanity will interact with AI. At the foundation of these products is the Platform Engineering team. In this role, you will lead the design and development of core data storage, streaming, caching, and indexing platforms and underlying systems. You’ll also get widespread exposure to the forefront of the AI race as Scale sees it in enterprises, startups, governments, and large tech companies. You will: Drive the architecture, design, implementation, and reliability of our foundational data platforms and systems, working closely with stakeholders and internal customers to understand and refine requirements. Collaborate with cross-functional teams to define, design, and deliver new features. Proactively identify opportunities for, and driving improvements to, current programming practices, including process enhancements and tool upgrades. Present technical information to teams and stakeholders, providing

mongodbredisaws
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16 days ago

About Scale Scale’s mission is to develop reliable AI systems for the world’s most important decisions. As the leading AI data foundry, we provide the high-quality data and full-stack technologies that power the world’s most advanced models — fueling breakthroughs in generative AI, defense, and autonomous vehicles. We partner with leading enterprises and governments to bring AI into production that performs when it matters most, combining rigorous evaluation with full-stack deployment so our customers can build AI they can trust. About the Team Applied Intelligence Systems (AIS) is part of the Scale Generative AI Platform (SGP), focused on pushing the frontier of what agentic applications can do across diverse enterprise and government use cases. We build the infrastructure and tooling that power agentic AI in production, paired with applied ML research, design, and evaluation to ensure these systems perform reliably at the scale our customers demand. AIS spans multiple workstreams — agent evaluation and oversight, orchestration and tool-use infrastructure, model and systems optimization, and applied research on new agent capabilities — and this role is not scoped to any single one of them. We’re growing fast, with increasing traction across both commercial and public sector customers, and we’re just getting started — this team will define what dependable, production-grade agentic AI looks like. About the Role As a Staff Machine Learning Research Engineer, you will operate across the full breadth of AIS’s technical needs — wherever the hardest ML problem in agentic AI happens to be that quarter. This could mean training and fine-tuning models, designing evaluation and observability systems, building improvement loops from production data, prototyping novel agent architectures, or designing internal systems and tooling that boost productivity across teams. You’re not tied to one team’s roadmap; you’re expected to move to where the technical leverage is highest, and t

awsrestmachine learning
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16 days ago

Scale has been the leading AI data foundry, helping fuel the most exciting advancements in AI, including frontier model training, enterprise adoption, defense applications, and autonomous vehicles. Our mission is to develop reliable AI systems for the world's most important decisions. The next frontier for AI is the physical world. We're looking for an AI Product Manager to own the Robotics vertical within our Physical AI team. In this role, you'll own both the development of the data and training environments (the teleoperated demonstrations, real-world collections, simulated tasks, and annotation products that labs use to train and evaluate robot policies) and the "data as a product" strategy that powers them. You'll understand where physical AI is headed, decide what robot tasks and embodiments are worth collecting, how to source and structure the underlying data, and how to turn deep domain knowledge into a defensible product. The ideal candidate has lived inside robotics or physical AI research, and is able to pair that domain understanding with a sense for where current robot policies succeed and fail in real-world workflows. You'll translate that expertise into datasets, environments, and evaluation frameworks that teach robots to do real physical work, and you'll be the domain expert Scale's most important customers and their leading researchers turn to. A strong entrepreneurial & go-to-market mindset will be necessary. What You'll Do Own the Robotics AI roadmap & data strategy: Set product direction for the robotics training stack and the data strategy behind it — what data we collect, on which hardware and embodiments, and what we source internally vs. through our marketplace. Establish a vision for where physical AI is heading, driving execution across engineering, operations, and go-to-market teams. Build partnerships with research teams at frontier labs: Work directly with researchers at leading physical AI labs to understand where their robot p

awsrestai
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Scale AI
📍 San Francisco• Full-time• From $252K/yr
16 days ago

Scale GP (Scale Generative AI Platform) is an enterprise-grade Generative AI platform that provides APIs for knowledge retrieval, inference, evaluation, and more. We are looking for a strong engineer to join our team and help us build and scale our product in a fast-paced environment. The ideal candidate will have a strong understanding of software engineering principles and practices, as well as experience with large-scale distributed systems. You will be responsible for owning large new areas within our product, working across backend, frontend, and interacting with LLMs and ML models. You will solve hard engineering problems in scalability and reliability. You will: Own large new areas within our product Work across backend, frontend, and interacting with LLMs and ML models Deliver experiments at a high velocity and level of quality to engage our customers Work across the entire product lifecycle from conceptualization through production Be able, and willing, to multi-task and learn new technologies quickly Ideally you'd have: 7+ years of full-time engineering experience, post-graduation Experience scaling products at hyper growth startups Experience tinkering with or productizing LLMs, vector databases, and the other latest AI technologies Proficient in Python or Javascript/Typescript, and SQL Experience with Kubernetes Experience with major cloud providers (AWS, Azure, GCP) Compensation packages at Scale for eligible roles include base salary, equity, and benefits. The range displayed on each job posting reflects the minimum and maximum target for new hire salaries for the position and may be inclusive of several career levels at Scale; it will be determined during the interview process based on work location and additional factors, including job-related skills, experience, qualifications, interview performance, and relevant education or training. Scale employees in eligible roles are also granted equity based compensation, subject to Board of Director approval

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Scale AI
📍 San Francisco• Full-time• From $252K/yr
16 days ago

About Scale AI At Scale, our mission is to develop reliable AI systems for the world's most important decisions. Our products provide the high-quality data and full-stack technologies that power the world's leading models, and help enterprises and governments build, deploy, and oversee AI applications that deliver real impact. Scale Frontier Data is the organization behind the training and evaluation data that frontier labs depend on. We build the systems, tooling, and expert workflows that turn hard human expertise into signals that models can learn from, across reasoning, coding, agentic tool use, and domain expertise. Reinforcement learning environments are now the center of gravity for that work: the difference between a model that demos well and a model that reliably completes long-horizon work is almost always the quality of the environments and reward signals it was trained against. Responsibilities As a Staff Software Engineer, RL Environments, you'll own the technical foundation for how Scale builds, runs, verifies, and delivers RL environments at scale. An RL environment is a real piece of software: a containerized world with real dependencies, real state, real tools, and a grader that has to be correct even when the agent is creative about breaking it. Building one is a full-stack engineering problem. Building thousands of them reproducibly, cheaply, with trustworthy reward signals and throughput measured in millions of rollouts is a systems problem that very few people have solved. You'll work on both. You'll design the platform: sandboxed execution, environment packaging and versioning, rollout orchestration, trajectory capture, verifier frameworks, and the authoring surfaces that let engineers and domain experts produce environments without reinventing infrastructure each time. And you'll go deep on the environments themselves by instrumenting real applications, designing task suites that expose specific capability gaps, and building graders that

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Tenstorrent
📍 Austin• Full-time• $100K – $500K/yr
16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. Tenstorrent is seeking talented Physical Design Engineers to implement high-performance blocks for our industry-leading CPU and AI/ML architectures. You'll own the complete implementation flow from synthesis to tapeout, working alongside world-class engineers to push the boundaries of performance, power, and area. If you're passionate about crafting silicon that powers the future of AI computing and thrive on solving complex design challenges, we want you on our team. This role is hybrid , based out of Austin, TX, Santa Clara, CA or Fort Collins, CO. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are A hands-on engineer with deep expertise in SOC/ASIC physical design and a track record of successful tapeouts. Passionate about optimizing PPA through innovative implementation techniques and close RTL collaboration. Strong problem solver who excels at debugging complex issues across design hierarchies. Collaborative team player who thrives in fast-paced, technically challenging environments. What We Need BS/MS/PhD in EE/ECE/CE/CS with proven experience in synthesis, PnR, and timing closure on taped-out designs. Expertise with industry-

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Tenstorrent
📍 Austin• Full-time• $100K – $500K/yr
16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. We’re looking for a Staff Forward Deployed Engineer who’s excited to build with the engineers using the AI computers Tenstorrent makes. You will create continuity between customers, engineering, and AI inference service products. This is an engineering role first: you contribute production code, operate deployments, and you can explain a trade-off to customer leadership as clearly as to core engineering teams. This is a high-autonomy role with direct customer impact. This role is remote, based out of North America, with preference near one of our main hubs: Santa Clara, CA; Austin, TX; or Toronto, ON. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are You understand how accelerator compute, memory, and networking topology constrain AI workloads, and don't treat hardware as a black box. You're an early adopter of AI for your work from coding to building agentic workflows that multiply your impact. You work directly with customers to understand their challenges and provide effective solutions. You are comfortable debugging across the full inference stack: from failing requests, through the serving layer, down to OOMs or kernel dispatch if n

awskubernetesmachine learning
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Tenstorrent
📍 Boston• Full-time• $100K – $500K/yr
16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. We’re looking for a Field Application Engineer who’s wired for AI/ML, fluent in real-world problem-solving, and excited to build with the people actually using what we make. You will collaborate closely with the sales team and enterprise customers, leveraging your deep technical knowledge in AI to drive the adoption of our products and solutions. This is a customer-facing role that requires both technical expertise and excellent communication skills to convey complex technical concepts to non-technical stakeholders. This role is remote based out of North America with preference near one of our main hubs Santa Clara, CA; Boston, MA; or Toronto,ON. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are You’ve lived in the AI/ML trenches, whether as a field engineer, a solutions architect, or the one tapped in when things needed to “just work.” You speak both machine and human. Whether it’s a researcher or a skeptical executive, you know how to break things down and bring them to life. You’re fired up about generative models, LLMs, and the edge of what’s possible when software meets purpose-built silicon. Work directly with customers in mee

awsmachine learningai
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16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. At Tenstorrent, we're building cutting-edge AI compute solutions. Developing diagnostics programs to validate the functionality and stress the performance of our solutions is a critical part of delivering exceptional products. We are looking for Engineers to join our Diagnostics Development team. These engineers will work closely with our firmware, software, board, ASIC design and verification teams to ensure that the ASICs, boards, and AI compute systems meet the highest standards of quality and performance. This role is hybrid, based out of Toronto, Canada. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are You're curious, hands-on, and excited by the challenge of building powerful systems that sit at the intersection of hardware and software. You enjoy working close to the metal, whether that’s writing code, debugging hardware, or exploring how systems perform under stress. You thrive in collaborative environments and love learning from teammates across disciplines like firmware, ASIC design, and manufacturing. You’re motivated by impact and want to contribute to technology that’s shaping the future of AI and computing. What We Need A

awsaisem
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16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. Join Tenstorrent as a Staff Reliability Engineer and help define the reliability strategy behind the next generation of AI computing systems. In this highly visible technical leadership role, you'll drive reliability from architecture through production, partnering across hardware, software, and manufacturing teams to build high-performance AI platforms that set the standard for uptime, durability, and quality. If you're passionate about solving complex engineering challenges and influencing products at scale, you'll have the opportunity to shape technology powering the future of AI. This role is hybrid, based out of Toronto, Canada. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are You've spent 8+ years in reliability engineering, ideally in high-performance computing, AI hardware, or data center systems. You're comfortable with the statistical side of the job, HALT, HASS, ALT, MTBF, Weibull analysis, and FMEA are all familiar territory. You can work through a technical problem in a thermal lab and then explain the risks and trade-offs clearly to leadership. You're good at bringing people together, mechanical, electrical, thermal, softw

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Tenstorrent
📍 Toronto• Full-time
16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. Tenstorrent is looking for a Firmware Engineer working on microcontrollers and SoCs, focused on low-level C/C++ development and board bring-up. You’ll implement and debug firmware, develop boot/power/reset sequences, and use lab tools to diagnose issues across the hardware–software boundary. You’ll collaborate closely with hardware, board, and system software teams while building strong skills in modern embedded platforms, RTOS/Embedded Linux, and automated testing. This role is hybrid, based out of Toronto, Canada. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are An experienced embedded engineer with a strong foundation in computer engineering, electrical engineering, computer science, or a related field, and a track record of building reliable software for real-world systems. A strong problem solver who enjoys working where software meets hardware and can move comfortably between architecture, implementation, debugging, and system-level thinking. Curious by nature and energized by complex challenges, with a willingness to explore new technologies, development approaches, and AI-assisted tools to make engineering more effective. A thou

awslinuxai
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Tenstorrent
📍 Austin• Full-time• $100K – $500K/yr
16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. Our Tensix team is building custom AI compute cores, RISC-V CPUs, and chiplet-based architectures for datacenter, edge, and automotive AI. Design Verification Engineers on this team validate compute IP and subsystems and build scalable DV infrastructure to keep verification fast, automated, and production-grade. This role is hybrid, based out of Toronto, ON, Austin, TX or Belgrade, Serbia. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are Experienced in modern verification methodologies with strong SystemVerilog skills and exposure to structured testbench development. Comfortable working from block-level to system-level verification and reasoning about microarchitecture behavior from specs and waveforms. Proficient in Linux environments with Python, or Bash scripting for automate builds, parse logs, manage CI pipelines. Skilled in coverage-driven verification and confident debugging across RTL, testbench, and workload scenarios. Motivated by AI hardware and eager to learn verification strategies for new architectures and domains. What We Need Contribute to verification of Tensix IP and subsystems from early planning through tape-out, owning cov

pythonawsci/cd
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16 days ago

Tenstorrent is leading the industry on cutting-edge AI technology, revolutionizing performance expectations, ease of use, and cost efficiency. With AI redefining the computing paradigm, solutions must evolve to unify innovations in software models, compilers, platforms, networking, and semiconductors. Our diverse team of technologists have developed a high performance RISC-V CPU from scratch, and share a passion for AI and a deep desire to build the best AI platform possible. We value collaboration, curiosity, and a commitment to solving hard problems. We are growing our team and looking for contributors of all seniorities. At Tenstorrent, we build open, state of the art compute for real workloads and real developers.You will own CPU core‑level verification, shaping how our out‑of‑order RISC‑V CPUs behave in silicon. This role is hybrid, based out of Bangalore, India. We welcome candidates at various experience levels for this role. During the interview process, candidates will be assessed for the appropriate level, and offers will align with that level, which may differ from the one in this posting. Who You Are You bring 8+ years in CPU verification or closely related digital design. You know high‑performance out‑of‑order CPU microarchitecture in depth. You work comfortably with RTL, waveforms, logs, and complex debug scenarios. You communicate clearly across design, DV, emulation, and post‑silicon teams. What We Need Plan and drive functional verification for CPU core features and complex microarchitectural scenarios. Develop UVM, assembly, and C/C++ based stimulus, functional models, and coverage for ISA, RISC-V extensions, and un-core components. Debug simulation and emulation regressions using RTL understanding, waveforms, and logs to identify and resolve issues efficiently. Build and enhance coverage models, testbenches, and debug infrastructure to improve verification quality and coverage closure. Collaborate with design, validation, and

awsgitai
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