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Staff Principal Engineer Jobs

3,518 active opportunities · Updated for October 2026

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Explore current staff principal engineer jobs. Use filters to narrow by work mode, employment type, experience and date posted.

Synthesia is the world’s leading AI video platform for business, used by over 90% of the Fortune 100. Founded in 2017, the company is headquartered in London, with offices and teams across Europe and the US. As AI continues to shape the way we live and work, Synthesia develops products to enhance visual communication and enterprise skill development, helping people work better and stay at the center of successful organizations. Following our recent Series E funding round, where we raised $200 million, our valuation stands at $4 billion. Our total funding exceeds $530 million from premier investors including Accel, NVentures (Nvidia's VC arm), Kleiner Perkins, GV, and Evantic Capital, alongside the founders and operators of Stripe, Datadog, Miro, and Webflow. About the role Almost every company can now produce training video at scale. Almost none of them can tell you whether any of it made someone better at their job. We're building the product that closes that gap: an agentic, real-time experience where people practice live, dynamic scenarios, and where organisations finally get signal on genuine readiness instead of a simple metric tied to course completion. This is a 0-to-1 bet on what comes after content, which is practice, and proof. You'll own a domain within it from strategy to ship. Why now: Real-time, agentic AI has only just become good enough to hold a convincing live scenario. The window to define this category is open now, and we intend to own it. The problem you're solving Today, the most you can do to assess whether someone has genuinely learned something is watch them complete a module or pass a quiz. The behaviours that matter in real roles, in real moments, are rarely tested reliably. We have the underlying technology to change that. What we need is a PM who can turn that into a product that an enterprise will use to prepare their people, and that a end user actually wants to engage with. What you'll be doing Owning the multi-quarter strategy for a

S
1mo ago

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake is seeking a Principal People Partner to serve as the primary strategic advisor to our Finance and Legal leadership organizations, including direct partnerships with the Chief Financial Officer and Chief Legal Officer / General Counsel. This is a highly visible, staff-plus role designed for an experienced People Partner who operates with executive presence, strong independent judgment, and the ability to shape people strategy at scale. This role is based in our Menlo Park office, with in-office attendance required three days per week. Due to the nature of ELT partnership, location flexibility is not available for this position. The Principal People Partner will work closely with senior Finance and Legal leaders, the G&A People Partner leadership team, and People Centers of Excellence to drive organizational effectiveness, leadership capability, and business-aligned people strategy. This role reports to the Director, G&A People Partners. THE IMPACT YOU WILL MAKE: As a Principal People Partner, you will operate at the intersection of business strategy, leadership effectiveness, and organizational design, influencing outcomes well beyond your immediate client group. You will: Serve as a trusted advisor to executive leadership: Partner directly with the CFO, G

aigorust
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Reddit is a community of communities. It’s built on shared interests, passion, and trust, and is home to the most open and authentic conversations on the internet. Every day, Reddit users submit, vote, and comment on the topics they care most about. With 100,000+ active communities and approximately 130 million daily active unique visitors, Reddit is one of the internet’s largest sources of information. For more information, visit www.redditinc.com . Reddit’s Ads Data Science team is looking for a Senior Staff Data Scientist to lead the scientific strategy behind Reddit’s ads measurement and signal systems. This role sits at the center of how Reddit proves advertiser value, improves signal quality, builds privacy-aware measurement systems, and connects ads exposure to real advertiser outcomes. As a Senior Staff Data Scientist for Ads Measurement, you will be the principal architect of our technical vision and the driving force behind the next generation of our measurement ecosystem. In a landscape rapidly shifting due to privacy regulations, browser changes, and evolving platform dynamics, you will spearhead innovation across experimental design (incrementality/lift), identity, signals, and privacy-safe 1P/3P measurement. This is a high-visibility, high-impact role requiring a rare blend of deep experimentation & causal inference expertise, strategic foresight, and the ability to influence cross-functional executives and industry standards. You will not just adapt to the changing ad-tech environment, you will redefine how we measure value. Responsibilities Technical Vision & Strategy: Define the long-term data science vision & strategy across ads measurement, signal quality, identity, attribution, and privacy. Establish how Reddit should evaluate advertiser value, measurement quality, and signal utility across first-party and third-party products. Set the Cross-Pillar Measurement Science Strategy: Define the long-term data science strategy across a

pythonsqlrest
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Pfizer
📍 Massachusetts• $99.2K – $165.4K/yr
10 days ago

Why Patients Need You Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world. What You Will Achieve As part of the Comparative Medicine team, you will support the Research & Development site by managing a vivarium to deliver flawless animal care and welfare and will assure the quality of care and the animal facility environment is in compliance with local regulations and AAALAC International guidelines partnering with Research and Development Research Units and Partner lines to facilitate study support. It is your hard work along with innovative ideas and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe. How You Will Achieve It Assure that the care and welfare of laboratory animals is provided in compliance with local regulations and AAALAC International guidelines. Manage and engage animal care and technical staff in the pursuit of flawless animal care and welfare by ensuring adherence to established policies and procedures. Support the career and personal development of the animal care and technical staff. Assist with a centralized CM training program for research animal care and use for animal care staff, principal investigators and research technicians throughout WRD. Participate in the direction of a centralized CM program of occup

airecruitment
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T
Twilio
📍 - US• Full-time• Remote• $159.2K – $176.9K/yr
1mo ago

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join the team as Twilio’s next Staff Product Designer (Channels UX) . About the job At Twilio, we are shaping the future of communications, empowering millions of developers and hundreds of thousands of businesses globally to build personalized customer experiences. We are looking for visionary, highly strategic Staff Product Designers (L4) to join our Channels UX team. In this role, you will serve as a foundational systems thinker and design leader overseeing Twilio's core communication products (including Voice, Email, and SendGrid infrastructure). Rather than focusing on a single silo, you will help us treat channels agnostically to design cohesive, multi-channel journeys inside Twilio's modern One Console ecosystem. You will own information architecture, naming frameworks, complex API configurations, and developer workflows that establish long-term trust and usability for builders worldwide. This is a phenomenal opportunity to act as a principal d

REMOTErestaigo
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This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your role at Baxter You will support plant operations by planning, scheduling, and coordinating maintenance activities that ensure the safe and reliable operation of facility equipment and systems. This role handles preventive, corrective, and emergency maintenance from initial request through completion, while partnering with cross-functional teams, vendors, and technicians to minimize downtime and maintain operational efficiency. What you'll be doing Schedule preventive maintenance work in accordance with the preventive maintenance program Schedule corrective and emergency maintenance work, utilizing internal and/or external resources Receive and triage requests from multiple functional groups and schedule the resulting maintenance work Identify and implement corrections to the maintenance program Identify and procure materials, consumables, and maintenance spare parts Manage multiple contracts and billing for embedded contractors and recurring fees including janitorial staff, c

recruitment
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This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your Role at Baxter THIS IS WHERE you build trust to achieve results As an Asst Mgr, Sales - Pharma , you will be responsible for driving primary sales through product promotion in defined territory. The role involves engaging with anesthetists, healthcare professionals (HCPs), paramedical staff, hospital purchase authorities, distributors, and channel partners to ensure product availability, demand generation, and business expansion. Role requires strong critical thinking, consultative selling capabilities, and data-driven decision-making. They possess the ability to identify growth opportunities, lead complex customer relationships, implement market development initiatives, and consistently deliver business results in a highly driven healthcare environment. Location and Territory Coverage: Base Location: Chennai, India Territ

procurementrecruitment
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This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your Role at Baxter THIS IS WHERE you build trust to achieve results As an Asst Mgr, Sales, you will be responsible for driving primary sales through product promotion in defined territory by meeting HCPs and para medical staff, Coordinating with commercial or purchase authorities and channel partners for ensuring supply and liquidation of products. Drive awareness and adoption through activations in the territory/accounts. What you'll be doing Strategic Imperative: Drive awareness and adoption on Anesthetics amongst Anesthetists in the assigned territories. Baxter is the only company to offer the most commonly used modern inhaled anesthetics for general anesthesia. This includes a proprietary inhaled anesthetic, SUPRANE (desflurane, USP), AERRANE (isoflurane, USP) and SEVOFLURANE (sevoflurane, USP). Planning: Monthly account wis

recruitment
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C
9 days ago

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. POSITION SUMMARY CVS Health is looking for hands-on, passionate people who want to join a high energy and growing team to make a difference in customers’ lives and who want to be on the forefront of digital innovation that aims to reinvent what a pharmacy and a health care company can be in the digital world. Currently, we are seeking a Staff Software Engineer – Search / AI who as a Senior technical leader, be responsible for driving architecture, design, and delivery of scalable, cloud-native platforms built on microservices architecture and AI capabilities. This role combines deep hands-on engineering with strategic leadership to build intelligent, distributed systems. The right candidate will be a strong analytical thinker and be able to simplify complex problems, processes or projects into component parts explore and evaluate them systematically. We love to collaborate and help each other and we want someone to share that ideology. Expectations for the Role Drive enterprise architecture and technical strategy with strong focus on microservices-based design and AI platform engineering Design and develop highly scalable microservices architectures, including APIs, domain-driven services, and event-driven systems Lead the development and integration of AI/ML solutions, including LLMs, Retrieval-Augmented Generation (RAG), and agentic frameworks Develop sc

REMOTEpythonjavaaws
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C
Cvshealth
📍 Fair Oaks Ranch
9 days ago

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Job Purpose and Summary: At CVS Health, we are focused on transforming health care for our customers and making our company a great place to work. We help people navigate the health care system – and their personal health care – by improving access, lowering costs, and being a trusted partner for every meaningful moment of health. Within our Retail locations, we bring this promise to life with heart every day. Our Staff Pharmacists play a critical role in cultivating a culture of excellence in their pharmacy by acting as a role model for all, demonstrating genuine care, and setting the bar for the pharmacy team. As a Staff Pharmacist, you play a critical role at the forefront of delivering our purpose, modeling our values, and demonstrating genuine, authentic care for our patients. In addition to supporting the Pharmacy Manager in leading and directing the pharmacy team, you are accountable for supporting the management, oversight, and operation of all aspects within your pharmacy. The Staff Pharmacist’s responsibilities include, but are not limited to: Living our purpose by helping to manage and improve patient health through safe and appropriate dispensing, counseling, and immunizing practices Taking direction from the Pharmacy Manager and overseeing the pharmacy as their proxy during bench shifts without overlap, including strengthening pharmacy pe

customer service
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C
9 days ago

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Job Purpose and Summary: At CVS Health, we are focused on transforming health care for our customers and making our company a great place to work. We help people navigate the health care system – and their personal health care – by improving access, lowering costs, and being a trusted partner for every meaningful moment of health. Within our Retail locations, we bring this promise to life with heart every day. Our Staff Pharmacists play a critical role in cultivating a culture of excellence in their pharmacy by acting as a role model for all, demonstrating genuine care, and setting the bar for the pharmacy team. As a Staff Pharmacist, you play a critical role at the forefront of delivering our purpose, modeling our values, and demonstrating genuine, authentic care for our patients. In addition to supporting the Pharmacy Manager in leading and directing the pharmacy team, you are accountable for supporting the management, oversight, and operation of all aspects within your pharmacy. The Staff Pharmacist’s responsibilities include, but are not limited to: Living our purpose by helping to manage and improve patient health through safe and appropriate dispensing, counseling, and immunizing practices Taking direction from the Pharmacy Manager and overseeing the pharmacy as their proxy during bench shifts without overlap, including strengthening pharmacy performan

customer service
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C
9 days ago

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Job Purpose and Summary: At CVS Health, we are focused on transforming health care for our customers and making our company a great place to work. We help people navigate the health care system – and their personal health care – by improving access, lowering costs, and being a trusted partner for every meaningful moment of health. Within our Retail locations, we bring this promise to life with heart every day. Our Staff Pharmacists play a critical role in cultivating a culture of excellence in their pharmacy by acting as a role model for all, demonstrating genuine care, and setting the bar for the pharmacy team. As a Staff Pharmacist, you play a critical role at the forefront of delivering our purpose, modeling our values, and demonstrating genuine, authentic care for our patients. In addition to supporting the Pharmacy Manager in leading and directing the pharmacy team, you are accountable for supporting the management, oversight, and operation of all aspects within your pharmacy. The Staff Pharmacist’s responsibilities include, but are not limited to: Living our purpose by helping to manage and improve patient health through safe and appropriate dispensing, counseling, and immunizing practices Taking direction from the Pharmacy Manager and overseeing the pharmacy as their proxy during bench shifts without overlap, including strengthening pharmacy pe

customer service
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