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Ai Native Startup Manager in New York

648 active opportunities · Updated October 2026

Explore current ai native startup manager jobs in New York. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $192K/yr

Quick readStrong listing-quality and freshness signals

As Engineering Manager for Threat Detection, you will lead a high-performing team that powers Datadog's detection program. Threat Detection is the organization responsible for keeping Datadog ahead of an evolving threat environment: closing coverage gaps faster, raising the bar on signal quality, and shipping detections that hold up under the scale and complexity of cloud-native infrastructure. Your team will combine direct detection expertise, platform engineering, and applied AI to ship detections at a pace and scale traditional rule-writing alone cannot match. Examples of what your team will work on include detection-authoring agents, the detection platform that powers every rule in production, coverage analysis, alert triage and response automation, and the evaluation infrastructure that holds these systems to a high bar of fidelity. Detection authorship is a shared responsibility across the organization, and your team will contribute both by building the systems that scale our authoring capacity and by writing detections directly when their domain expertise is the right tool. You will partner closely with our Security Incident & Response Team (SIRT), Cyber Threat Intelligence (CTI), AI Engineering teams, and Datadog's broader Security organization. This is a high-impact leadership role: you will grow a team of security and software engineers responsible for building and executing our detection and AI strategy. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Lead the strategy, roadmap, and execution of Datadog Security's shift to AI-accelerated detection and response. Drive development of high-fidelity detections as a shared responsibility across the organization, ensuring your team's systems and direct contributions raise the bar on coverage and

PythonCI/CDRestAI
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📍 New York, New York, United States· Full-time
✓ High-confidence listing

$175K – $215K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. We’re looking for a Senior Software Engineer to join our Network Engineering team to accelerate building and scaling our innovative systems that support our growing identity platform. In this role, you will build the next-generation infrastructure that underpins all systems at CLEAR. The ideal candidate for this role will approach challenges with an eye toward reliability, simplicity, and scalability. What You'll Do: Develop and maintain a streamlined process for engineers to effortlessly build and deploy scalable and reliable software-defined networking solutions on AWS. Enhance our compute platform (Kubernetes) by integrating new functionalities and features, focusing on AWS networking services and concepts such as VPCs, Route Tables, Security Groups (SGs), ALBs/ELBs, and Route53, as well as implementing Kubernetes networking solutions like service mesh (Istio) to optimize service communication and management. Collaborate across engineering teams to advocate for and implement best practices in observability, utilizing tools like Splunk or Datadog to ensure robust network monitoring. Act as a product owner for our infrastructure, collecting feedback and requirements from engineering teams to address pain points and develop solutions, particularly in the realm of AWS networking and cloud-native design principles. What you're great at: 6+ years of extensive experience in infrastructure and platform development, particularly in software-defined networking and AWS cloud services. Proficient in writing production-grade softwar

PythonAWSKubernetesGit
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📍 New York, New York, United States· Full-time
✓ High-confidence listing

From $105K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. We’re looking for an early career Software Engineer to join our Infrastructure team to accelerate building and scaling our innovative systems that support our growing identity platform. In this role, you will build the next-generation infrastructure that underpins all systems at CLEAR. The ideal candidate for this role will approach challenges with an eye toward reliability, simplicity, and scalability. What You'll Do: Develop and maintain a streamlined process for engineers to effortlessly build and deploy scalable and reliable software-defined networking solutions on AWS. Enhance our compute platform (Kubernetes) with new functionalities and features, focusing on AWS networking services and concepts such as VPCs, Route Tables, Security Groups (SGs), ALBs/ELBs, and Route53, optimize service communication and management. Collaborate across engineering teams to advocate for and implement best practices in observability, utilizing tools like Splunk or Datadog to ensure robust network monitoring. Act as a product owner for our infrastructure, collecting feedback and requirements from engineering teams to address pain points and develop solutions, particularly in the realm of AWS networking and cloud-native design principles. What you're great at: 0-2 years of experience in infrastructure and platform development and AWS cloud services. Proficient in Python, with understanding of Kubernetes and container orchestration tools like EKS and ECS. Understand AWS networking services, including VPC design, SGs, NATGWs, ALBs/ELBs, Rout

PythonAWSKubernetesGit
C
📍 New York, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Senior Manager, Platform Engineering / DevOps Who Are You You are an experienced Senior Manager / emerging Staff-level leader in DevOps and Platform Engineering with strong technical depth and demonstrated leadership in delivering enterprise-scale cloud platforms. You bring a balanced mix of hands-on engineering expertise, team leadership, and execution rigor. You excel in driving outcomes in complex, multi-stakeholder environments, guiding teams to deliver secure, scalable, and high-quality platform solutions. You are comfortable leading engineers, managing stakeholders, and owning delivery across multiple workstreams. You demonstrate: A strong ownership mindset with accountability for delivery and outcomes Ability to translate business needs into actionable engineering roadmaps Solid expertise in cloud-native platforms, DevOps practices, and SRE principles Capability to lead teams and influence without requiring extensive tenure Role Responsibilities Development & Enforcement Own and execute the H100 platform engineering roadmap, aligned to enterprise priorities and program milestones Drive delivery of GCP-based platform capabilities (GKE, networking, IAM, CI/CD, observability) Establish and enforce engineering standards, best practices, and ADR compliance</li

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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -72.3%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. Our New Business team at Plaid combines deep product and industry knowledge and is focused on bringing Plaid to an ever-broadening set of businesses. Our thesis is that the financial services landscape is evolving at a breakneck pace, and every modern company building in the fintech space needs the gold standard of financial technology infrastructure to win, scale, and delight users. You'll be the one helping us achieve this vision. As a New Business Representative for our FinTech segment, you'll forge the path to finding new clients and prospecting digital-native fintechs, neobanks, alternative lending platforms, and personal finance applications for us to target. We are looking for extraordinary sales professionals with SaaS/tech and/or outbound selling experience who can demonstrate the added value of Plaid and what impact our API suite can have on supercharging a fintech's growth, security, and user experience. In this role, you will be responsible for organizational mapping, prospecting individuals, driving engagement, setting opportunities for AEs, taking qualification calls, and nurturing early opportunities. The ideal candidate is customer-centric, resilient, challenges the status quo, and h

AWSGitRestAgile
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $119K/yr

Quick readStrong listing-quality and freshness signals

As Lead of Web Content Engineering & AI Visibility on Datadog’s Web Experience team, you will own how we use our content management system (CMS), build and maintain the pages across datadoghq.com, and improve the technical SEO and AI discoverability that help those pages get found and cited. You will partner across Marketing, UX, and Engineering to turn content into effective web experiences and bring discoverability insights into planning and prioritization. You will also use AI, agents, and automation to shorten the path from recommendation to published page and make reporting and insights more accessible to stakeholders. This role offers the opportunity to shape how Datadog evolves its web presence as search and AI-driven discovery continue to change. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Build and maintain product, pricing, solutions, careers, about, and other pages across Datadog’s web properties, partnering with Engineering to support CMS templates, components, permissions, and workflows Partner with Content, Product Marketing, and UX to prioritize web work, structure content for the web, and ensure requests have the scope and lead time needed for high-quality execution Own technical SEO and AI discoverability across Datadog’s web properties, including structured data, heading structure, internal linking, metadata, crawlability, and how AI answer engines interpret and cite pages Establish consistent structural standards across owned web properties and monitor site health to identify and address issues Use AI, agents, and automation to streamline the path from recommendation to published experience and deliver dashboards and insights with less manual effort Who You Are: Experienced building and maintaining web pages in a modern CMS suc

AIRustMarketingSEO
LA
📍 New York, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

We are investing in agentic AI and need a Senior AI Engineer to lead the design and delivery of these systems. This is a foundational hire: you will own both the agent-facing workstreams — pipelines, orchestration, conversational interfaces — and the underlying context layer that makes them reliable, including memory management, knowledge graph integration, and retrieval infrastructure. You will work closely with data engineers, project leads, and client stakeholders, and play a key role in shaping how Lynx builds and ships AI solutions at scale. What This Involves: Lead the architecture and delivery of agentic AI systems end-to-end: agents, orchestration, tool use, and multi-step reasoning workflows. Own the context layer: design and implement memory architectures (episodic, semantic, working memory) and integrate GraphRAG and knowledge graph retrieval into agentic pipelines. Build robust RAG systems — including vector retrieval, graph traversal, and hybrid search — and ensure retrieval quality through evaluation frameworks. Translate client requirements into technical designs, presenting approaches and trade-offs to both technical and non-technical stakeholders. Define standards and reusable patterns for agentic AI development that other engineers at Lynx can build on. Set up observability, evaluation, and monitoring pipelines to ensure AI systems perform correctly in production. Requirements: 5–8 years of software or ML engineering experience, with at least 2–3 years building LLM-based or agentic AI systems in production. Deep hands-on experience with agentic frameworks (LangChain, LlamaIndex, AutoGen, CrewAI, or similar) and LLM APIs (OpenAI, Anthropic, etc.). Strong understanding of agent design patterns: ReAct, planning loops, tool use, multi-agent coordination, and memory architectures. Practical experience with GraphRAG or knowledge graph-based retrieval (e.g., Neo4j, Microsoft GraphRAG) and vector databases (Pinecone, Weaviate, Qdrant, etc.). Proficiency in

PythonReactDockerKubernetes
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $128K/yr

Quick readStrong listing-quality and freshness signals

We’re looking for an experienced sourcing leader to join the Datadog Procurement team and help grow the Strategic Sourcing group. Make an impact by partnering closely with senior technology and business leaders, owning our fastest-growing AI, neocloud, and inference spend end-to-end, and continuing to prove the value that Strategic Sourcing brings to the organization. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the AI spend category end-to-end, covering foundation-model and AI APIs, AI development and productivity tools, and AI-enabled SaaS (with neocloud and inference compute as an emerging area), while developing and executing category strategies aligned to business objectives Champion AI and automation adoption across the sourcing function by identifying tools (e.g. Claude, ChatGPT) and building repeatable workflows that make sourcing faster, smarter, and more scalable Lead high-value AI vendor negotiations spanning foundation-model and API agreements, AI development and productivity tools, and AI SaaS, structuring seat- and consumption-based pricing across net-new purchases and strategic renewals, and building neocloud and GPU-capacity capability as the category grows Partner with Engineering and Finance to turn architectural and consumption trade-offs into commercial business cases, forecasts, and savings targets Build pricing and consumption models and apply FinOps discipline to quantify buying scenarios and uncover savings across a fast-moving spend base Work alongside executive and senior technology leadership as a trusted advisor on AI and neocloud investment decisions, influencing strategy and commercial trade-offs at the leadership level Track category KPIs (savings, pipeline, cycle time), monitor AI market, vendor, and pricing trends,

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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $320K/yr

Quick readStrong listing-quality and freshness signals

As a Research Scientist on our team, you will partner with Research Engineers, working on fundamental research problems and collaborating with Datadog's product and engineering teams to translate research advances into products. Building on our track record of AI-powered solutions (e.g., Bits AI , Bits Evolve , and our time series foundation model ), Datadog AI Research tackles high-risk, high-reward problems grounded in real-world challenges in cloud observability and security. We are focused on two research areas: World Models for Observability -- Training multimodal foundation models that learn the joint dynamics of distributed systems across metrics, traces, logs, topology, and events. These models power advanced forecasting, anomaly detection, root cause analysis, counterfactual simulation ("what if?"), and provide a learned planning backbone for our autonomous agents. Trained Agents for Observability -- Post-training models to operate autonomously across Datadog's domain. SRE incident response is our first target, with a clear path to code repair, security response, and infrastructure optimization. We build the simulation environments, RL training loops, and evaluation infrastructure needed to train agents that match or surpass frontier models at a fraction of the cost. What You'll Do: Conduct research in generative AI and machine learning, building specialized foundation models and trained agents for observability Train multimodal models on large-scale, diverse telemetry data (metrics, logs, traces, topology, events) using distributed training infrastructure Design and build simulated environments and RL training loops for on-policy agent training and evaluation Collaborate with cross-functional teams (Product, Engineering) to integrate capabilities like multimodal world modeling and autonomous agents into Datadog's products Stay at the forefront of foundation models, world models, and RL-based agent research Contribute to r

GitMachine LearningAIGo
H
📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community Most AI engineering jobs are a thin wrapper around a model API. This role is different. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to the source document, and route ambiguous cases to human experts for review. Our users make decisions that impact real healthcare outcomes, so “good enough” is not good enough. Building AI systems that are accurate, reliable, auditable, and scalable is at the core of this role. As a Senior AI Applied Engineer, you will design, build, deploy, and operate production AI systems used at scale within one of the largest health insurers in the United States. You will own solutions end-to-end, from user experience and APIs to model orchestration, evaluation frameworks, infrastructure, and production operations. Why Join Us Build production AI systems where LLMs are in the critical path, not just demos or proofs of concept. Work on extraction, retrieval, agentic workflows, and human-review systems that process real healthcare data at scale. Own projects end-to-end across frontend, backend, AI orchestration, infrastructure, deployment, and operations. Solve challenging problems around accuracy, explainability, traceability, and reliability in regulated environments. Ship quickly in a small, high-impact team that embraces AI-assisted development and rigorous quality standards. Build systems that continuously improve through expert feedback, evaluations, and human-in-the-loop workflows. Key Responsibilities Design, develop, and deploy full-stack AI-powered application

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📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community You have shipped AI products before. You understand the difference between a demo and a production system. You have strong opinions about evaluation frameworks because you have experienced the consequences of operating without them. You are at your best when you own architecture decisions while continuing to build and deliver critical code yourself. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to source documents, and route complex cases to human experts. The output of these systems supports healthcare decisions that impact real members. As a Lead AI Applied Engineer, you will provide technical leadership for AI-enabled products and platforms, define architectural direction, establish engineering standards, and personally design and build the most critical components of our systems. You will lead through both technical expertise and execution, helping the team deliver reliable, scalable, and auditable AI solutions in a highly regulated healthcare environment. Why Join Us Lead the architecture of production AI systems where LLMs are foundational to the product experience. Make key technical decisions regarding model selection, system boundaries, platform architecture, and build-versus-buy strategies. Own the highest-risk and highest-impact technical challenges involving reliability, explainability, and correctness. Influence engineering culture and establish standards that shape how the team builds and ships AI products. Work on systems operating at meaningful scale, processing millions of documents and supporting healthcare decisions across a large member population. Partner

JavaScriptTypeScriptPythonReact
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📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community Every large organization is making critical decisions today about how it will leverage AI over the next decade. Few have leaders who can both define that vision and demonstrate its viability through hands-on engineering. This role requires both. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations to source documents, and route difficult cases to human experts. These capabilities support decisions that impact real healthcare outcomes for members. As a Principal AI Applied Engineer, you will define the technical strategy, architectural standards, and long-term vision for AI-enabled products across the organization. You will influence enterprise-wide decisions regarding AI platforms, model strategies, engineering standards, and technology investments while remaining deeply hands-on in prototyping, experimentation, architecture, and software development. This is the highest-level individual contributor role within the AI Applied Engineering organization. Success requires exceptional technical depth, organizational influence, strategic thinking, and the ability to translate emerging AI capabilities into scalable, reliable, and responsible production systems. Why Join Us Shape the long-term AI architecture and engineering direction for a large enterprise healthcare organization. Influence how AI-enabled products are designed, built, evaluated, deployed, and governed across multiple teams. Drive strategic decisions involving models, vendors, platforms, infrastructure, and shared capabilities. Prototype and validate emerging technologies before the organization invests at scale.</

JavaScriptTypeScriptPythonReact
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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -82%

About the Team The AI Deployment Engineering team is responsible for ensuring the safe and effective deployment of Generative AI applications for developers and startups. We act as a trusted advisor and thought partner for our customers, working to build an effective backlog of GenAI use cases for their industry and drive them to production through strong technical guidance. As an AI Deployment Engineer (ADE) in the OpenAI for Global Affairs team, you’ll help government and non-profit agencies transform their organization through solutions such as automated content generation, contextual search, and novel applications that make use of our newest, most exciting models and technology. About the Role OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. We believe that achieving our goal requires effective engagement with public policy stakeholders and the broader community impacted by AI. The Global Affairs team builds authentic, collaborative relationships with public officials and the broader AI policymaking community to inform and support our shared work in these domains. We ensure that insights from policymakers inform our work and - in collaboration with our colleagues and external stakeholders - help shape policy guardrails, industry standards, and safe and beneficial development of AI tools. We are looking for an AI Deployment Engineer to collaborate directly with our Global Affairs team to help public sector actors unlock the benefits of OpenAI tools and products, aiming to broadly benefit humanity. This includes supporting a workforce organization deploying Certifications programs or advising a government partner on responsible implementation practices. Your role will integrate technical expertise with our mission to ensure that artificial general intelligence benefits all of humanity. In this role, you will: Technical Enablement & Deployment Serve as the primary technical advisor for Global Affairs partnersh

JavaScriptPythonJavaAWS
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -85.2%

From $192K/yr

Quick readStrong listing-quality and freshness signals

Databases and data stores are at the center of our applications, for legacy applications and modern AI applications alike. Yet most observability and optimization approaches lack a holistic approach or application context. Datadog has been on a mission to revolutionize how databases are operated, flipping what is often seen as a black box of complexity prone to security and performance risks, into a well oiled machine enabling our builders and businesses to move faster and smarter. We’re looking for an experienced product manager passionate about joining this mission to lead this product opportunity. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Lead ambitious investments that rethink how customers operate and get value from their databases, diving into ambiguity, working with our customers on new models, and shipping new products and changes to existing products. Develop a deep understanding of our customers and their issues, what problems are really behind those issues, and how we can improve how databases are operationalized across SRE teams, DBAs and application developers. Continuously refine your understanding of database management systems and datastores from SQL and OLTP based to NoSQL e.g. AWS RDS, PostgreSQL, SQL Server, MongoDB, MySQL, etc Define, build and launch the next generation of database monitoring and optimization capabilities for our customers Join a talented engineering team with a record of disrupting observability approaches to further the mission of demystifying and optimizing databases using your team’s creativity, alongside your customers’ problems, as a key resource. Collaborate with other Product teams in Datadog to maintain and improve all Datadog products, improve the seamless integration across th

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📍 New York, NY, United States
✓ High-confidence listingCompany trend +310%
Quick readStrong listing-quality and freshness signals

Become a part of our caring community Help shape practical, responsible AI solutions that improve healthcare experiences and outcomes. Humana’s Enterprise AI organization develops safe, scalable AI solutions across our Insurance and CenterWell businesses. We bring together product managers, data scientists, engineers, policy experts, and business leaders to apply emerging technology to meaningful healthcare challenges. As Associate Director of Applied AI, you will lead teams that design, build, and deploy enterprise AI solutions, with a focus on generative AI and intelligent agents. You will connect technical strategy to business needs, guide responsible delivery in a regulated environment, and help teams turn promising ideas into measurable outcomes for members, patients, and associates. Key Responsibilities Lead and mentor teams developing production-ready AI solutions that improve healthcare delivery, member experiences, and business operations. Help define and execute the roadmap for applied AI initiatives in alignment with enterprise priorities and business needs. Guide the evaluation and adoption of machine learning, generative AI, large language models, multimodal models, and intelligent agent technologies. Oversee scalable APIs, frameworks, data pipelines, retrieval-augmented generation solutions, and agent orchestration capabilities. Partner with product, data science, engineering, architecture, security, and business teams to translate requirements into reliable solutions. Establish standards for AI evaluation, obse

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