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Ai Native Startup Manager in United States

5,082 active opportunities · Updated October 2026

Explore current ai native startup manager jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI, in close collaboration with our capital partners, is building the world’s most advanced AI infrastructure ecosystem. Our Industrial Compute organization develops and deploys large-scale AI campuses designed to support the next generation of frontier model training and inference workloads. The Hardware Operations team is responsible for ensuring the reliability, availability, and lifecycle health of OpenAI’s compute infrastructure. We partner closely with Data Center Operations, Fleet Health Engineering, Manufacturing, Network Infrastructure, Capacity Planning, and our infrastructure partners to maintain world-class operational performance across rapidly expanding AI environments. As we scale globally, we are building the operational frameworks, reliability standards, and sustaining engineering practices required to support thousands of GPUs and servers across multiple campuses. About the Role We are seeking a Datacenter Hardware Technician Lead to serve as the senior on-site technical authority for hardware reliability and fleet health at one of OpenAI’s flagship AI campuses. This role operates at the intersection of hardware operations, sustaining engineering, and fleet reliability. You will partner closely with Cloud Service Provider operations teams, OpenAI fleet-health engineers, hardware engineering teams, and OEM vendors to identify, diagnose, and resolve hardware issues affecting production systems. Beyond day-to-day operational support, you will drive root cause investigations, reliability improvement initiatives, lifecycle management programs, and operational readiness efforts. You will help establish hardware maintenance standards, operational procedures, and best practices that scale across future OpenAI infrastructure deployments. The ideal candidate combines deep hands-on datacenter hardware expertise with strong troubleshooting, failure analysis, and cross-functional leadership skills. Candidates must be able to sit onsite at our

AWSLinuxRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team: GTM Innovation is a product engineering team with a charter to automate 100% of digital knowledge work in OpenAI's GTM, so sellers spend more time directly with customers. AGI-level reasoning doesn’t mean organization-level transformation “just works” out of the box; orgs must be redesigned around abundant intelligence and persistent virtual coworkers. Our team builds and scales a fleet of virtual coworkers that operate as full-time members of the account team, and redefines how our human-first revenue organization interacts with their agentic teammates. About the Role We’re looking for product mindset software engineers to join the GTM Innovation team. As a product engineer on this team, you’ll help OpenAI meet the world at scale. You’ll partner closely with go-to-market teams to understand their workflows, identify leverage points, and ship novel solutions using OpenAI’s API platform. You’ll move quickly from prototype to production, and your work will directly shape how customers experience our technology in the field. This role is ideal for engineers who want to be close to users, own end-to-end outcomes, and help define entirely new categories of enterprise software. In this role, you will: Build high-impact applications and tools that accelerate OpenAI’s go-to-market efforts Work across the full product lifecycle for GTM: prototype, iterate, ship, and maintain Embed with Sales, Technical Success, and Revenue Operations to identify user needs and build for them Apply OpenAI’s models in novel ways to solve real-world customer and internal workflow problems Translate learnings into feedback for Applied and Research teams to inform product development You’ll thrive in this role if you: Have 4+ years of experience as a software/ML/product engineer working on user-facing systems Former founder, or early engineer at a startup who built a product from scratch is a plus Are fluent in Python or JavaScript and comfortable building full-stack applications

JavaScriptPythonJavaAWS
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team The Fleet team at OpenAI supports the computing environment that powers our cutting-edge research and product development. We oversee large-scale systems that span data centers, GPUs, networking, and more, ensuring high availability, performance, and efficiency. Our work enables OpenAI’s models to operate seamlessly at scale, supporting both internal research and external products like ChatGPT. We prioritize safety, reliability, and responsible AI deployment over unchecked growth. About the role As a software engineer on the Fleet High Performance Computing (HPC) team, you will be responsible for the reliability and uptime of all of OpenAI’s compute fleet. Minimizing hardware failure is key to research training progress and stable services, as even a single hardware hiccup can cause significant disruptions. With increasingly large supercomputers, the stakes continue to rise. Being at the forefront of technology means that we are often the pioneers in troubleshooting these state-of-the-art systems at scale. This is a unique opportunity to work with cutting-edge technologies and devise innovative solutions to maintain the health and efficiency of our supercomputing infrastructure. Our team empowers strong engineers with a high degree of autonomy and ownership, as well as ability to effect change. This role will require a keen focus on system-level comprehensive investigations and the development of automated solutions. We want people who go deep on problems, investigate as thoroughly as possible, and build automation for detection and remediation at scale. In this role, you will: Build and maintain automation systems for provisioning and managing server fleets. Develop tools to monitor server health, performance, and lifecycle events. Collaborate with clusters, networking, and infrastructure teams. Partner with external operators to ensure a high level of quality. Identify and fix performance bottlenecks and inefficiencies. Continuously improve automati

PythonSQLAWSLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Foundations Research team works on high-risk, high-reward ideas that could shape the next decade of AI. Our goal is to advance the science and data that enable our training and scaling efforts, with a particular focus on future frontier models. Pushing the boundaries of data, scaling laws, optimization techniques, model architectures, and efficiency improvements to propel our science. The Search team sits within Foundations, building agentic search by co-designing model–system interfaces with the core search stack (serving, indexing, retrieval) to translate model intent into reliable, real-world actions. Operating at the frontier of AI and information retrieval, the team develops large-scale systems that transform and index vast corpora, enabling models to reason over global knowledge and act dependably. In close partnership with researchers, we rapidly bring modeling breakthroughs into production and redefine how intelligent systems discover, retrieve, and synthesize information at planetary scale. About the Role We’re looking for a researcher focused on our embedding retrieval efforts. You’ll work with a a team of world-class research scientists and engineers developing foundational technology that enables models to retrieve and condition on the right information, at the right time. This includes designing new embedding training objectives, scalable vector store architectures, and dynamic indexing methods. This work will support retrieval across many OpenAI products and internal research efforts, with opportunities for scientific publication and deep technical impact. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. Responsibilities Tackle embedding models and retrieval systems optimized for grounding, relevance, and adaptive reasoning. Collaborate with a team of researchers and engineers building end-to-end infrastructure for training, evaluati

AWSRestMachine LearningAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The RL and Reasoning team drives the core reasoning paradigm and has created groundbreaking innovations such as o1 and o3. They focus on pushing the boundaries of reinforcement learning research, building next-generation generative models, and deploying them at scale. About the Role As a Research Engineer/Research Scientist at OpenAI, you will advance the frontier of AI alignment and capabilities through cutting-edge RL methods. Your work will sit at the heart of training intelligent, aligned, and general-purpose agents, including the systems that power various models. We’re looking for people who have a background in reinforcement learning research, are able to iterate quickly, and are proficient at coding. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. You might thrive in this role if: You love being on the cutting edge of RL and language model research. You’re a self-starter who takes initiative and ownership of ideas, driving them to completion. You value principled approaches, simple experiments in tightly-controlled settings, and reaching trustworthy conclusions which stand the test of time. You thrive in a fast-paced, dynamic, and technically complex environment where rapid iteration is key. You’re comfortable diving into a large ML codebase to debug and improve it. You have a deep understanding of machine learning and machine learning applications. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and human needs at its core, and to achieve our mission, we must encompass and value the many different perspectives, voices, and experiences that form the ful

AWSRestMachine LearningAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team The Fleet team at OpenAI supports the computing environment that powers our cutting-edge research and product development. We oversee large-scale systems that span data centers, GPUs, networking, and more, ensuring high availability, performance, and efficiency. Our work enables OpenAI’s models to operate seamlessly at scale, supporting both internal research and external products like ChatGPT. We prioritize safety, reliability, and responsible AI deployment over unchecked growth. About the role As a software engineer on the Fleet Hardware team, you will be responsible for the reliability and uptime of all of OpenAI’s compute fleet. Minimizing hardware failure is key to research training progress and stable services, as even a single hardware hiccup can cause significant disruptions. With increasingly large supercomputers, the stakes continue to rise. Being at the forefront of technology means that we are often the pioneers in troubleshooting these state-of-the-art systems at scale. This is a unique opportunity to work with cutting-edge technologies and devise innovative solutions to maintain the health and efficiency of our supercomputing infrastructure. Our team empowers strong engineers with a high degree of autonomy and ownership, as well as ability to effect change. This role will require a keen focus on system-level comprehensive investigations and the development of automated solutions. We want people who go deep on problems, investigate as thoroughly as possible, and build automation for detection and remediation at scale. In this role, you will: Build and maintain automation systems for provisioning and managing server fleets. Develop tools to monitor server health, performance, and lifecycle events. Collaborate with clusters, networking, and infrastructure teams. Partner with external operators to ensure a high level of quality. Identify and fix performance bottlenecks and inefficiencies. Continuously improve automation to reduce manual work

PythonSQLAWSLinux
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Fleet team builds core components to enable productive research from small to state of the art scale across OpenAI, with the goal of accelerating progress towards AGI. We frequently collaborate with other teams to speed up the development of new state-of-the-art capabilities. About the Role As we scale up with more researchers and engineers joining OpenAI, we seek a pragmatic and passionate engineer with a strong focus on the development experience for both engineers and scientists. In this role, you will be responsible for building and maintaining systems that allow our research + engineering organization to iteratively develop, test, and deploy new features reliably, with high velocity, and with a frictionless and fast development cycle. You will help oversee and drive to the vision of how we should build, test and deploy software. You will drive the design of our continuous integration pipelines, testing infrastructure, training and support around our build system. Our current environment relies heavily on Python, Rust, and C++, which you will take ownership of and strive to transform into a state of the art development experience for research. Ultimately, your role will be to provide the necessary tools and metrics to support our fast-paced culture and ensure a stable, scalable platform for growth, while also fostering a seamless and low friction experience for OpenAI’s research. This role is based in San Francisco, CA. For a San Francisco role, we use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. You might thrive in this role if you: Have supported large monorepo development and deployment before Are a proficient Python programmer working in large monorepos Are proficient with Docker and Kubernetes Experienced in CI/CD About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boun

PythonAWSDockerKubernetes
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Training Runtime designs the core distributed machine-learning training runtime that powers everything from early research experiments to frontier-scale model runs. With a dual mandate to accelerate researchers and enable frontier scale, we’re building a unified, modular runtime that meets researchers where they are and moves with them up the scaling curve. Our work focuses on three pillars: high-performance, asynchronous, zero-copy tensor and optimizer-state-aware data movement; performant, high-uptime, fault-tolerant training frameworks (training loop, state management, resilient checkpointing, deterministic orchestration, and observability); and distributed process management for long-lived, job-specific and user-provided processes. We integrate proven large-scale capabilities into a composable, developer-facing runtime so teams can iterate quickly and run reliably at any scale, partnering closely with model-stack, research, and platform teams. Success for us is measured by raising both training throughput (how fast models train) and researcher throughput (how fast ideas become experiments and products). About the Role As a Training Performance Engineer, you’ll drive efficiency improvements across our distributed training stack. You’ll analyze large-scale training runs, identify utilization gaps, and design optimizations that push the boundaries of throughput and uptime. This role blends deep systems understanding with practical performance engineering — analyzing GPU kernel performance, collective communication throughput, investigating I/O bottlenecks, and sharding our models so we can train them at massive scale. You’ll help ensure that our clusters are running at peak performance, enabling OpenAI to train larger, more capable models with the same compute budget. This role is based in San Francisco, CA. We use a hybrid work model of three days in the office per week and offer relocation assistance to new employees. In this role, you will: Profil

PythonAWSRestAI
O
📍 United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but operational in how we execute, and we support every product and research effort at OpenAI. Our tenets include prioritizing for impact, enabling researchers and developers, preparing for future transformative technologies, and fostering a strong, collaborative security culture. About the Role OpenAI is seeking a Security Software Engineer to join the Infrastructure Security (InfraSec) team. InfraSec safeguards the core of OpenAI’s research and production environments—GPU supercomputing clusters, multi-cloud infrastructure, datacenters, networking, storage, and the critical services that power our frontier AI models. Our charter spans everything from bare-metal hardware and firmware to Kubernetes clusters, service meshes, and the data pathways that carry highly sensitive model weights and user data. As a Security Software Engineer, you will design and build critical foundational services, such as authentication systems, egress/ingress proxies, access brokers, and key management platforms, that demand high standards of reliability, scalability, and software craftsmanship. These systems form the security backbone of OpenAI’s supercomputing environment and must remain robust under intense scale and adversarial pressure. In this role, you will: Architect and implement production-grade security services (e.g., auth services, access brokers, secure proxies, key-management infrastructure) that provide strong guarantees across hardware, operating systems, Kubernetes, networks, and CI/CD. Partner with infrastructure and research engineers to embed security into high-performance compute clusters, enabling rapid model training and deployment without compromising protection. Develop automation and detection tooling to continuously identif

PythonAWSAzureGCP
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team We’re hiring software engineers to make the Workload team more productive. The Workload team maintains the core components of OpenAI’s training and inference frameworks and helps execute frontier experiments. About the Role We’re looking for someone who cares about the developer experience of working in and around OpenAI’s core training and inference frameworks. In this role you will: Be responsible for optimizing the development workflows of the engineers around you Work within various Workload teams to address their specific needs, but collaborate with the centralized teams that own various aspects of development experience Optimize iteration speed, both broadly, and in particular by optimizing specific teams’ CI Improve reliability, for instance, by driving testing strategy for particular components Work through the long tail of things that it takes to build libraries and systems that will delight researchers You might thrive in this role if: You are motivated by helping people. You believe a thing that separates great teams from good teams are the players willing to do whatever work it takes, without ego. You believe in the power of developer experience. Something magical happens when people can quickly and confidently iterate on a simple codebase, but this magic is fragile and must be fought for. When you see someone trip over something, no matter how small, your first instinct is asking yourself what it would take for that to not happen again. Your second instinct is clicking merge on the PR you’ve already written to make it so. You are pragmatic. You have the ability to see the world through a perfectionist’s eyes, but are not yourself a perfectionist. You know which problems to pick and when to switch to making progress on a different problem. You like going end-to-end on things. You love co-design — that feeling when you were only able to find the right solution because you both deeply understand the users that interact with a system and the

PythonAWSRestAgile
O
📍 United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but are operational in how we do our work, and are committed to supporting all products and research at OpenAI. Our Security team tenets include: prioritizing for impact, enabling researchers, preparing for future transformative technologies, and engaging a robust security culture. About the Role OpenAI is seeking a Security Engineer to join our Infrastructure Security (InfraSec) team. InfraSec protects the foundations of OpenAI’s research and production environments, spanning GPU supercomputing clusters, multi-cloud infrastructure, datacenters, networking, storage, and the critical services that power our frontier AI models. Our charter includes securing everything from bare-metal hardware and firmware, to Kubernetes clusters and service meshes, to data storage and access pathways for highly sensitive model weights and user data. In this role, you will: Design and build security controls across diverse layers (e.g., physical hardware, firmware/BMC, OS, Kubernetes, networks, and CI/CD) to defend against sophisticated adversaries and insider threats. Collaborate with engineering and security teams to drive deployment of security enhancements and control changes across broad-scale infrastructure. Tackle high-impact projects such as checkpoint encryption, network isolation, secret management, and machine identity, while continuously raising the security bar for emerging AI workloads. Take a generalist approach to building security controls, balancing a mix of security expertise and broad technical skillsets to adapt to evolving challenges. You will thrive in this role if you have: Deep understanding of security principles, best practices, and common vulnerabilities. A proactive mindset, with the ability to identify and address secu

AWSAzureKubernetesCI/CD
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Strategic Finance team at OpenAI plays a critical role in shaping the company’s long-term trajectory. We partner closely with Product, Engineering, and Go-To-Market teams to inform high-stakes decisions through rigorous data science and economic modeling. As part of our expanding Data Science function, we’re building a best-in-class Forecasting capability to drive real-time, data-driven decision-making across user growth, revenue, compute infrastructure, and more. We are developing scalable forecasting infrastructure to help us understand and anticipate business dynamics in an increasingly complex, usage-based world. Our models are foundational to planning, pricing, operational efficiency, and growth strategy - supporting key investment decisions and unlocking OpenAI’s full potential. About the Role We’re looking for a senior Machine Learning Data Scientist to lead our forecasting initiatives. You’ll be one of the founding members of the Forecasting pillar within Strategic Finance Data Science, responsible for building and scaling robust, interpretable, and production-ready forecasting systems. Your models will power critical business decisions by predicting core metrics such as DAU/WAU, revenue, LTV, compute consumption, and profitability. This is a highly cross-functional role, requiring technical excellence, strong product intuition, and business acumen. You’ll collaborate with product managers, researchers, engineers, and finance leaders to operationalize forecasting insights, influence company-wide strategy, and build foundational forecasting capabilities at OpenAI. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Build statistical and machine learning models to solve forecasting needs across product, finance, infrastructure, and GTM domains. Own the end-to-end modeling lifecycle , including scoping, feature engineerin

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s Platform team powers how millions of developers and enterprises build with our models. We provide APIs and agentic solutions used by global startups and fortune 500s. We work closely with product, engineering, design, and go-to-market to build a world-class platform that pushes the frontier of AI capabilities. About the Role As a Data Scientist on the Platform team, you will drive a data-driven culture for OpenAI’s API and B2B solutions. You’ll define the metrics that matter for developer success and enterprise value, measure the impact of new models and features, and partner with PMs and engineers to improve model quality, reliability, latency, and cost. Your work will shape how thousands of products adopt agentic AI. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will Embed with the Platform product team as a trusted partner, uncovering ways to improve developer experience, reliability, and usage growth Define north-star metrics across the developer funnel (activation, retention, growth), as well as latency/cost guardrails for new features and models Design and interpret A/B tests and controlled rollouts (e.g., new model versions, pricing/limits, new API features, new B2B products) Build source-of-truth dashboards and self-serve data tools for product, engineering, and go-to-market teams Translate product learnings into actionable feedback for Research (e.g., failure modes, eval gaps, model response quality) You might thrive in this role if you have 5+ years in a quantitative role in ambiguous, high-growth environments (platforms, APIs, or B2B products a plus) Depth in SQL and Python, with a track record proposing, designing, and running rigorous experiments Experience defining and operationalizing metrics from scratch (including reliability/latency/cost and safety) Strong cross-functional communication with PMs, enginee

PythonSQLAWSRest
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team: GTM Innovation is a product engineering team with a charter to automate 100% of digital knowledge work in OpenAI's GTM, so sellers spend more time directly with customers. AGI-level reasoning doesn’t mean organization-level transformation “just works” out of the box; orgs must be redesigned around abundant intelligence and persistent virtual coworkers. Our team builds and scales a fleet of virtual coworkers that operate as full-time members of the account team, and redefines how our human-first revenue organization interacts with their agentic teammates. About the Role We’re looking for Full Stack software engineers with a product mindset to join the GTM Innovation team. As a product engineer on this team, you’ll help OpenAI meet the world at scale. You’ll partner closely with go-to-market teams to understand their workflows, identify leverage points, and ship novel solutions using OpenAI’s API platform. You’ll move quickly from prototype to production, and your work will directly shape how customers experience our technology in the field. This role is ideal for engineers who want to be close to users, own end-to-end outcomes, and help define entirely new categories of enterprise software. In this role, you will: Build high-impact applications and tools that accelerate OpenAI’s go-to-market efforts Work across the full product lifecycle for GTM: prototype, iterate, ship, and maintain Embed with Sales, Technical Success, and Revenue Operations to identify user needs and build for them Apply OpenAI’s models in novel ways to solve real-world customer and internal workflow problems Translate learnings into feedback for Applied and Research teams to inform product development You’ll thrive in this role if you: Have 4+ years of experience as a software/ML/product engineer working on user-facing systems Former founder, or early engineer at a startup who built a product from scratch is a plus Are fluent in Python or JavaScript and comfortable building full-s

JavaScriptPythonJavaAWS
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Our Robotics team is focused on unlocking general-purpose robotics and advancing toward AGI-level intelligence in dynamic, real-world environments. Working across the full model and systems stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the physical constraints of real-world systems to improve people’s lives. About the Role We're looking for an experienced Electrical Engineer to help develop the next generation of robotic systems at OpenAI. This role spans the full lifecycle of hardware development, from early concept exploration and prototyping through circuit design, component selection, PCB layout, bring-up, integration, and deployment. Engineers in this role are expected to independently drive significant hardware efforts from initial concept through deployment. You will translate ambiguous goals into concrete engineering plans, make key technical decisions, coordinate closely with cross-functional partners, and own execution through the iterations required to deliver a successful system. Many of the systems we build are still being defined. You will work closely with mechanical, firmware, software, controls, and research teams to evaluate new ideas, develop novel hardware, and integrate it into robotic platforms. Success in this role requires strong engineering judgment, comfort operating in ambiguous spaces, and the ability to balance rapid experimentation with the discipline required to build reliable and scalable systems. The ideal candidate enjoys building things from first principles and is equally comfortable evaluating a new technology, debugging a prototype on the bench, reviewing PCB layout details, and driving system integration efforts. You should be able to move quickly when appropriate, but also know when investing in robustness, simplicity, or infrastructure will create leverage for future development. This role is

PythonAWSRestAI
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