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Ai Oncology Portfolio Lead in New York

648 active opportunities · Updated October 2026

Explore current ai oncology portfolio lead jobs in New York. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$300.1K – $500.1K/yr

Quick readStrong listing-quality and freshness signals

Role Summary This role serves as the single point of accountability between USMAPPS and the Oncology Business Unit, owning access strategy, payer marketing, and brand-level contracting and pricing strategy across the full oncology portfolio. The role drives and owns outcomes, integrating all USMAPPS capabilities into one coherent access plan that directly supports the Oncology BU President and franchise leads. The Vice President is expected to operate at full strategic weight, lead a team aligned to oncology brands and franchise clusters, and be the single person the Oncology BU holds accountable for market access results. The Vice President, US Market Access Lead – Oncology reports directly to the Senior Vice President of US Market Access & Pfizer Patient Services (USMAPPS) with a dotted line to the Oncology BU President . This position requires close partnership with the Oncology BU President, franchise leads, Strategic Contracting & Analytic s , Strategic Account Management, the Patient Services, and USMAPPS leadership. The role sits on the Oncology BU leadership team and on the USMAPPS Leadership Team. Role Responsibilities 1. Oncology Access Strategy Ownership Develop and maintain a fully integrated brand market access plan for all oncology brands, covering payer marketing, contracting strategy, and pricing strategy in one coherent plan </

AIRecruitment
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📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$230.9K – $384.8K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. The US Precision Medicine Thoracic Franchise is entering its most consequential — and most complex — growth chapter. Our in-line thoracic portfolio spans two biomarker-defined populations: LORBRENA (lorlatinib) for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC), and the BRAFTOVI &#43; MEKTOVI (encorafenib &#43; binimetinib) regimen for BRAF V600E-mutant metastatic NSCLC. Both sit inside a molecularly driven treatment landscape where the right patient is identified by a biomarker signature. Winning here means mastering precision targeting: reaching narrow, high-value, genomically defined patient populations through the exact clinicians who test for and treat them. This is a people-management leadership role that demands a strong enterprise leader — one fluent in both commercial strategy and AI-enabled execution, and able to think and operate at the enterprise level. The colleague who leads this team will set a multi-year strategic vision, make thoughtful trade-off and resource-prioritization decisions across two brands, and influence senior leadership across the wider organizati

Machine LearningAIExcelRecruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$33 – $55/hr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary (GU) including both prostate and bladder, hematology-oncology and thoracic therapeutic areas. The primary purpose of this position will be to provide comprehensive day-to-day administrative support to the US Prostate Franchise Lead and to support the overall Franchise business. The Administrative Assistant will report to the US Prostate Vice President. In this role, the Administrative Assistant will be responsible for (but not limited to) heavy calendar management, coordination of meetings and events, development of agendas and meeting reports, slide development for select meetings, and requests and assembly of briefing materials, arranging travel and expense report preparation. As a working professional, he/she will be expected to handle tasks independently and in a proactive manner. <

AIExcelLogisticsRecruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$139.1K – $231.9K/yr

Quick readStrong listing-quality and freshness signals

As a leading biopharmaceutical company, Pfizer is dedicated to the discovery and delivery of high value therapies across a variety of disease areas. It is our mission to bring innovative medicines to patients that significantly improve their lives, and our priority is to ensure patients have access to these medicines. The Health Technology Assessment (HTA), Value & Evidence (HV&E) team is responsible for ensuring patients have affordable, timely access to medicines and vaccines by advancing innovative value and evidence solutions to inform healthcare decision-making. ROLE SUMMARY The HTA, Value & Evidence Senior Manager is responsible for development and execution of high-quality HV&E strategic efforts to support optimal access and reimbursement for treatments in Oncology. This role directly impacts the ability to achieve business objectives on a global basis by providing strategic guidance and robust evidence development relevant to achieve optimal global patient access by demonstrating the value of Oncology medicines. This position will be part of Pfizer’s dynamic HTA Value & Evidence team and will have the important role of managing health economics and outcomes research (HEOR) to generate data to support patient access to the GU Cancer Portfolio. This position will be working closely with the Oncology cross-functional teams (e.g., access, medical, clinical, commercial, etc.) and country teams to foster a culture that promotes innovation and thrives on doing better for Pfizer’s patients and society in general. This position will function in a closely aligned fashion with the Global Access Strategy and Pricing (GASP) team to ensure there is a single and coordinated view on strategy and project execution. This position will function with a ‘OnePfizer’ mindset and will work in a closely ali

AIProject ManagementRecruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$162.9K – $271.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. IBRANCE changed the treatment paradigm for metastatic breast cancer when it launched in 2015. As the brand approaches loss of exclusivity (LOE), this role owns its omnichannel and HCP marketing engine through the LOE timeframe and then carries that same omnichannel discipline forward to stand up NPP and digital execution for the Oncology Business Unit's next wave of breast cancer launches. This is a role for a marketing leader who thrives on solving complex problems in a competitive market and wants both halves of the brand lifecycle; defending an in-line asset through the tape, and building the omnichannel foundation a new set of launches will be built on. This individual must be able to excel in a fast-paced, matrixed environment, make immediate business impact, think outside the box, and actively contribute to a positive team culture. This role will focus on non-personal promotion (NPP), owning IBRANCE's nonpromotional strategy and digital/omnichannel execution (paid search, organic search, paid social, web analytics, search AI, media strategy,

AIExcelProject ManagementRecruitment
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📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$99.2K – $165.4K/yr

Quick readStrong listing-quality and freshness signals

Role Summary This position reports to the Director, Product Communications and Social Engagement Lead, and will execute the organic social strategy and community engagement across the Primary Care, Specialty Care, and Oncology businesses, as well as PfizerForAll handles. The role is responsible for delivering tactics against social communication strategies that amplify product narratives, foster meaningful connections, and protect brand reputation through compliant, social-by-design content, while ensuring alignment with overall brand and business objectives. The individual will own the editorial calendar, build high-performing communities, and operationalize safe, responsive, and compliant social engagement programs. The ideal candidate is someone proficient in hands-on execution and collaboration with cross-functional teams, including marketing, product, and digital. Key Responsibilities Strategy and Planning Help define the organic social strategy for Primary and Specialty Care brands and input into translation of brand narratives into platform-native content and series. Help build and maintain a channel-by-channel editorial calendar (quarterly and monthly) aligned to campaigns, corporate moments, data and regulatory milestones, and product needs; integrate tagging and UTMs. Content Operations and Execution Assist in the editorial process end to end: help brief, develop, adapt, and optimize organic posts and lightweight social extensions; enforce tone of voice and style guides. Support data and milestone moments through social, helping shape the communications approach and developing supporting content for owned corporate channels. Coordinate influencer and partner content where relevant, ensuring taxonomy, job-code tracking, and preview/QA workflows with agencies. Drive test

AIRecruitment
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $119K/yr

Quick readStrong listing-quality and freshness signals

As Lead of Web Content Engineering & AI Visibility on Datadog’s Web Experience team, you will own how we use our content management system (CMS), build and maintain the pages across datadoghq.com, and improve the technical SEO and AI discoverability that help those pages get found and cited. You will partner across Marketing, UX, and Engineering to turn content into effective web experiences and bring discoverability insights into planning and prioritization. You will also use AI, agents, and automation to shorten the path from recommendation to published page and make reporting and insights more accessible to stakeholders. This role offers the opportunity to shape how Datadog evolves its web presence as search and AI-driven discovery continue to change. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Build and maintain product, pricing, solutions, careers, about, and other pages across Datadog’s web properties, partnering with Engineering to support CMS templates, components, permissions, and workflows Partner with Content, Product Marketing, and UX to prioritize web work, structure content for the web, and ensure requests have the scope and lead time needed for high-quality execution Own technical SEO and AI discoverability across Datadog’s web properties, including structured data, heading structure, internal linking, metadata, crawlability, and how AI answer engines interpret and cite pages Establish consistent structural standards across owned web properties and monitor site health to identify and address issues Use AI, agents, and automation to streamline the path from recommendation to published experience and deliver dashboards and insights with less manual effort Who You Are: Experienced building and maintaining web pages in a modern CMS suc

AIRustMarketingSEO
B
📍 New York, New York, United States· Full-time
✓ High-confidence listing

$141.9K – $177.4K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Customer Experience at Brex The Customer Experience team is the connective tissue between Brex’s product and the companies that depend on it every day. We don’t just resolve issues — we surface insights, close feedback loops, and help shape the product roadmap. As Brex becomes an AI-native company, our CX organization leads that shift: building the systems, metrics, and workflows that let AI handle routine complexity while humans focus on judgment and relationships. We measure success not by tickets closed, but by customers who don’t need to contact us in the first place. What you’ll do Brex is looking for an experienced AI operator & leader to own the strategy and execution of AI-powered customer experience. You’ll lead the team responsible for Brex’s AI customer service platform — optimizing instruction sets, driving quality, and expanding AI across chat, voice, and email. You’ll also own the internal side of the equation: build

AIGoAccountingFinance
LA
📍 New York, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

We are investing in agentic AI and need a Senior AI Engineer to lead the design and delivery of these systems. This is a foundational hire: you will own both the agent-facing workstreams — pipelines, orchestration, conversational interfaces — and the underlying context layer that makes them reliable, including memory management, knowledge graph integration, and retrieval infrastructure. You will work closely with data engineers, project leads, and client stakeholders, and play a key role in shaping how Lynx builds and ships AI solutions at scale. What This Involves: Lead the architecture and delivery of agentic AI systems end-to-end: agents, orchestration, tool use, and multi-step reasoning workflows. Own the context layer: design and implement memory architectures (episodic, semantic, working memory) and integrate GraphRAG and knowledge graph retrieval into agentic pipelines. Build robust RAG systems — including vector retrieval, graph traversal, and hybrid search — and ensure retrieval quality through evaluation frameworks. Translate client requirements into technical designs, presenting approaches and trade-offs to both technical and non-technical stakeholders. Define standards and reusable patterns for agentic AI development that other engineers at Lynx can build on. Set up observability, evaluation, and monitoring pipelines to ensure AI systems perform correctly in production. Requirements: 5–8 years of software or ML engineering experience, with at least 2–3 years building LLM-based or agentic AI systems in production. Deep hands-on experience with agentic frameworks (LangChain, LlamaIndex, AutoGen, CrewAI, or similar) and LLM APIs (OpenAI, Anthropic, etc.). Strong understanding of agent design patterns: ReAct, planning loops, tool use, multi-agent coordination, and memory architectures. Practical experience with GraphRAG or knowledge graph-based retrieval (e.g., Neo4j, Microsoft GraphRAG) and vector databases (Pinecone, Weaviate, Qdrant, etc.). Proficiency in

PythonReactDockerKubernetes
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $128K/yr

Quick readStrong listing-quality and freshness signals

We’re looking for an experienced sourcing leader to join the Datadog Procurement team and help grow the Strategic Sourcing group. Make an impact by partnering closely with senior technology and business leaders, owning our fastest-growing AI, neocloud, and inference spend end-to-end, and continuing to prove the value that Strategic Sourcing brings to the organization. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the AI spend category end-to-end, covering foundation-model and AI APIs, AI development and productivity tools, and AI-enabled SaaS (with neocloud and inference compute as an emerging area), while developing and executing category strategies aligned to business objectives Champion AI and automation adoption across the sourcing function by identifying tools (e.g. Claude, ChatGPT) and building repeatable workflows that make sourcing faster, smarter, and more scalable Lead high-value AI vendor negotiations spanning foundation-model and API agreements, AI development and productivity tools, and AI SaaS, structuring seat- and consumption-based pricing across net-new purchases and strategic renewals, and building neocloud and GPU-capacity capability as the category grows Partner with Engineering and Finance to turn architectural and consumption trade-offs into commercial business cases, forecasts, and savings targets Build pricing and consumption models and apply FinOps discipline to quantify buying scenarios and uncover savings across a fast-moving spend base Work alongside executive and senior technology leadership as a trusted advisor on AI and neocloud investment decisions, influencing strategy and commercial trade-offs at the leadership level Track category KPIs (savings, pipeline, cycle time), monitor AI market, vendor, and pricing trends,

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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $192K/yr

Quick readStrong listing-quality and freshness signals

As a Senior Platform Product Manager focused on AI SDLC Trusted Throughput, you will define and drive the product strategy for enabling safe, reliable software delivery at AI-native scale across Datadog’s Internal Developer Platform. As AI accelerates development velocity and system complexity, you will help evolve SDLC systems from human-supervised workflows to platforms with built-in safety, observability, and correctness guarantees. You will partner closely with engineering, security, and developer platform teams to improve deployment reliability, operational visibility, and governance while enabling both engineers and AI agents to move quickly with confidence. This role offers the opportunity to shape foundational developer infrastructure and influence how AI-powered software delivery operates across Datadog. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the product strategy, roadmap, and execution for AI-native SDLC throughput and reliability initiatives across Datadog’s Internal Developer Platform Define and drive platform outcomes aligned to DORA metrics, balancing deployment velocity with reliability, change failure reduction, and operational safety Partner with engineering, infrastructure, security, and developer experience teams to build automated validation, auditability, and risk-scoring capabilities into deployment workflows Deliver actionable SDLC observability and diagnostic capabilities that connect executive-level metrics to operational signals across the software delivery lifecycle Drive systems that monitor and validate AI-generated or AI-attributed changes to ensure correctness, compliance, and trustworthy automation Serve as a cross-functional product leader across SDLC Foundations, Security Engineering, and compl

AIGoRustSpring
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📍 New York, California, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $330K/yr

Quick readStrong listing-quality and freshness signals

Datadog is expanding the Technical Solutions (TS) organization by seeking a customer-focused, deeply technical Distinguished Architect to join our Product Solutions Architecture (PSA) team. In this role, you will act as a technical multiplier for the world's leading AI labs and AI-native companies. You will bridge the gap between their bleeding-edge infrastructure aspirations and Datadog’s technology roadmap, ensuring our platform natively solves the unique observability challenges of training and deploying foundational models at scale. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Leadership : Demonstrate thought leadership in the AI/LLM space. Influence key decision makers and stakeholders by connecting technical capabilities to organizational and business impact. Advisory : Strategically partner with highly technical Founders, Heads of Infrastructure, and Research Lead peers. Guide them on best practices and emerging industry trends in the AI/LLM space. Lead high-level technical and architectural conversations around AI adoption. Presentations : Lead deep-dive architecture reviews and design engagements with customer teams and their leaders to share industry trends, best practices, and demonstrate how Datadog can support high-throughput hyper scale AI workloads. GTM : Identify emerging AI-native technology shifts and feed them directly back to Datadog Product Management. Co-create custom observability integrations and solutions alongside Product SAs to keep Datadog at the absolute forefront of the AI stack. Collaboration : Collaborate with Product Solutions Architecture (PSA), Sales, Sales Engineering and Marketing in providing high-quality technical resources to a broad audience of practitioners and economic buyers. Hiring : Assis

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $320K/yr

Quick readStrong listing-quality and freshness signals

As a Research Scientist on our team, you will partner with Research Engineers, working on fundamental research problems and collaborating with Datadog's product and engineering teams to translate research advances into products. Building on our track record of AI-powered solutions (e.g., Bits AI , Bits Evolve , and our time series foundation model ), Datadog AI Research tackles high-risk, high-reward problems grounded in real-world challenges in cloud observability and security. We are focused on two research areas: World Models for Observability -- Training multimodal foundation models that learn the joint dynamics of distributed systems across metrics, traces, logs, topology, and events. These models power advanced forecasting, anomaly detection, root cause analysis, counterfactual simulation ("what if?"), and provide a learned planning backbone for our autonomous agents. Trained Agents for Observability -- Post-training models to operate autonomously across Datadog's domain. SRE incident response is our first target, with a clear path to code repair, security response, and infrastructure optimization. We build the simulation environments, RL training loops, and evaluation infrastructure needed to train agents that match or surpass frontier models at a fraction of the cost. What You'll Do: Conduct research in generative AI and machine learning, building specialized foundation models and trained agents for observability Train multimodal models on large-scale, diverse telemetry data (metrics, logs, traces, topology, events) using distributed training infrastructure Design and build simulated environments and RL training loops for on-policy agent training and evaluation Collaborate with cross-functional teams (Product, Engineering) to integrate capabilities like multimodal world modeling and autonomous agents into Datadog's products Stay at the forefront of foundation models, world models, and RL-based agent research Contribute to r

GitMachine LearningAIGo
H
📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community Most AI engineering jobs are a thin wrapper around a model API. This role is different. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to the source document, and route ambiguous cases to human experts for review. Our users make decisions that impact real healthcare outcomes, so “good enough” is not good enough. Building AI systems that are accurate, reliable, auditable, and scalable is at the core of this role. As a Senior AI Applied Engineer, you will design, build, deploy, and operate production AI systems used at scale within one of the largest health insurers in the United States. You will own solutions end-to-end, from user experience and APIs to model orchestration, evaluation frameworks, infrastructure, and production operations. Why Join Us Build production AI systems where LLMs are in the critical path, not just demos or proofs of concept. Work on extraction, retrieval, agentic workflows, and human-review systems that process real healthcare data at scale. Own projects end-to-end across frontend, backend, AI orchestration, infrastructure, deployment, and operations. Solve challenging problems around accuracy, explainability, traceability, and reliability in regulated environments. Ship quickly in a small, high-impact team that embraces AI-assisted development and rigorous quality standards. Build systems that continuously improve through expert feedback, evaluations, and human-in-the-loop workflows. Key Responsibilities Design, develop, and deploy full-stack AI-powered application

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📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community You have shipped AI products before. You understand the difference between a demo and a production system. You have strong opinions about evaluation frameworks because you have experienced the consequences of operating without them. You are at your best when you own architecture decisions while continuing to build and deliver critical code yourself. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to source documents, and route complex cases to human experts. The output of these systems supports healthcare decisions that impact real members. As a Lead AI Applied Engineer, you will provide technical leadership for AI-enabled products and platforms, define architectural direction, establish engineering standards, and personally design and build the most critical components of our systems. You will lead through both technical expertise and execution, helping the team deliver reliable, scalable, and auditable AI solutions in a highly regulated healthcare environment. Why Join Us Lead the architecture of production AI systems where LLMs are foundational to the product experience. Make key technical decisions regarding model selection, system boundaries, platform architecture, and build-versus-buy strategies. Own the highest-risk and highest-impact technical challenges involving reliability, explainability, and correctness. Influence engineering culture and establish standards that shape how the team builds and ships AI products. Work on systems operating at meaningful scale, processing millions of documents and supporting healthcare decisions across a large member population. Partner

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