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Ai Senior Systems Engineer in California

75 active opportunities · Updated October 2026

Explore current ai senior systems engineer jobs in California. Filter by work mode, employment type, experience, department, date posted and distance.

G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. As the Director, Enterprise Transformation Communications at Gilead, you will lea

AIProject ManagementFinanceRecruitment
I
📍 California, United States
✓ High-confidence listing

$62.9K – $94.3K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Illumina is seeking a talented individual to fulfill a Scientist 1 role in next-generation sequencing (NGS) assay research and development. This is a unique opportunity to join a talented team of scientists at the frontier of innovation in spatial transcriptomics. At Illumina you will work in a dynamic, team-oriented environment and help create novel molecular biology assays that support expansion of Illumina’s spatial transcriptomics portfolio Responsibilities Design and execute lab-based experiments using biochemistry and molecular biology skills Troubleshoot and optimize workflows and assays to improve performance Innovate new spatial transcriptomics methods and devise solutions to technical issues Work independently and as part of an interdisciplinary team Effectively communicate experimental results and next steps to team members at regular meetings Maintain detailed records of experimental work and analysis Complete goals within defined timelines Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with th

Artificial IntelligenceAI
H
📍 California, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$180K – $270K/yr

Quick readStrong listing-quality and freshness signals

Lead RF Systems and Defense Engineer- HP IQ Description - Who We Are HP IQ is HP’s new AI innovation lab. Combining startup agility with HP’s global scale, we’re building intelligent technologies that redefine how the world works, creates, and collaborates. We’re assembling a diverse, world-class team—engineers, designers, researchers, and product minds—focused on creating an intelligent ecosystem across HP’s portfolio. Together, we’re developing intuitive, adaptive solutions that spark creativity, boost productivity, and make collaboration seamless. We create breakthrough solutions that make complex tasks feel effortless, teamwork more natural, and ideas more impactful—always with a human-centric mindset. By embedding AI advancements into every HP product and service, we’re expanding what’s possible for individuals, organisations, and the future of work. Join us as we reinvent work, so people everywhere can do their best work. About The Role HP IQ's Wireless Technology Team works cross-functionally with Electrical Engineering, Software, Mechanical Engineering, Product Design, Industrial Design, Program Management, and Operations to develop next-generation wearable and AI-connected products. As a Lead RF Systems & Desense Engineer, you will own the RF system architecture from concept through mass production. You will lead RF integration across Wi-Fi, Bluetooth, UWB, NFC and emerging wireless technologies while driving RF desense, coexistence, and wireless performance for highly integrated products. <span style=

I
📍 California, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. This position maintains and repairs the facility's structure, equipment and ground, including plumbing, electrical and HVAC. Key Responsibilities: Responsible for mechanical service calls and in-house repairs throughout facility and grounds. Performs skilled trade work, such as carpentry or painting in the construction, repair or alteration of structures such as walls, roofs or office fixtures. Monitor, maintain document and perform preventative maintenance on HVAC system including central plant. May provide guidance and oversee other personnel. May work from sketches, blueprints, and drawings. Act as liaison and supervise work of contractors. Be on call and able to respond 7/24/365. Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs. Requirements: Requires 2-5 years of related experience Ability to continually learn through on-t

Artificial IntelligenceAI
I
📍 California, United States
✓ High-confidence listing

$74.9K – $112.3K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. We are looking for a talented and motivated scientist to join the Assay Research and Development group. You will play an important role in developing new and novel sequencing library preparation assays that meet the high performance and robustness characteristics that our customers require. You will be responsible to design and execute experiments, collect data, perform analysis, draw conclusions and participate on product development teams. A background in molecular biology and biochemistry lab techniques is desired. Position Responsibilities: Designs and performs experiments of varying complexity and across a broad array of techniques, foresees issues and works to overcome obstacles to completing tasks or assignments, conceives of new ways to analyze the data and present it. Makes detailed technical observations and documents them in laboratory notebooks and confluence pages, etc. Plans, conducts, summarizes, reports consistent conclusions, and generates recommendations for follow up experiments and may suggest alternate strategies. <

Artificial IntelligenceAI
I
📍 California, United States
✓ High-confidence listing

$82.5K – $123.7K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Position Summary: The Sr. Materials Planner is responsible for ensuring optimal material availability for Illumina's instrument and spare parts portfolio by balancing supply, demand, inventory, and lead-times to support manufacturing, service, and customer needs. Responsibilities: Develop and execute material plans to support instrument manufacturing, service, repair, and refurbishment operations. Monitor material availability and proactively communicate shortages or surplus to prevent supply disruptions in the network. Manage inventory levels to balance customer service, operational readiness, and inventory investment. Review and recommend updates to planning parameters, lead times, and master data. Analyze demand and supply changes, communicate risks and mitigation plans. Partner with Procurement to resolve delivery issues and improve material availability. Support product lifecycle transitions from a material readiness perspective. Collaborate cross-functionally with Manufacturing, Service, Quality, Logistics, and Supply Plan

Artificial IntelligenceAISapExcel
I
📍 California, United States
✓ High-confidence listing

$82.5K – $123.7K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. *Candidate must be able to work out of our San Diego, Hayward, or Foster City locations* Position Summary This position will support the Regional Project Planning function within Global Facilities and provide facility planning and construction design management to facilitate execution at multiple project scales and delivery methods in an energetic and fast-paced environment. The role is responsible for construction project and renovation space planning, estimation, scheduling, and resourcing. This person will work closely with consultants and internal stakeholders to create functional area program, layout, and to coordinate facility infrastructure support needs. The ideal candidate for this role has proven ability to identify and resolve issues resourcefully and independently, and will work to understand key business drivers, applying this knowledge to decision making. We are looking for your talent, experience and initiative to join our growing team! Specific Responsibilities: Leading feasibility analysis and site master planning studies Tracking 3 year horizon of planned efforts to info

Artificial IntelligenceAIExcelProcurement
I
📍 California, Santa Clara, United States
✓ High-confidence listingCompany trend +315.4%
Quick readStrong listing-quality and freshness signals

Job Details: Job Description: Intel is shaping the future of technology to help create a better future for the entire world. Our work in pushing forward fields like AI, analytics, and cloud-to-edge technology is at the heart of countless innovations. With a career at Intel, you'll have the opportunity to use technology to power major breakthroughs and create enhancements that improve our everyday quality of life. Join us and help make the future more wonderful for everyone. Want to learn more? Visit our YouTube Channel or the link below. Life at Intel The Role and Impact As a Supply Chain Technical Analyst, you will play a vital role in optimizing and managing Intel's supply chain operations. You will develop and execute supply chain planning schedules, materials forecasts, build plans, and capacity requirements, ensuring seamless operations to meet customer needs. By analyzing data, identifying patterns, and modeling optimization strategies, you will directly contribute to creating more efficient supply chain solutions that drive cost-effectiveness and operational excellence. Business Group You will join Intel Foundry's Central Planning team, which plays a pivotal role in ensuring effective supply chain management for Intel's innovative manufacturing operations. This team works collaboratively between customers and Intel manufacturing to optimize supply while maximizing capacity utilization across all manufacturing stages. The group supports Intel's mission by driving operational efficiency and delivering exceptional value to customers. Key Responsibilities: Analyze supply chain data to identify trends, patterns,

SQLAISapExcel
I
📍 California, United States
✓ High-confidence listing

$155.6K – $233.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Responsibilities: Drive staff results by communicating job expectations, planning, monitoring and appraising job results, coaching and counseling employees, recognizing performance issues and driving improvement, developing, coordinating and enforcing systems, policies, procedures and productivity standards Establish strategic goals by gathering pertinent business, financial, service and operations information, choosing a course of action, defining objectives, and evaluating outcomes Maintain staff by recruiting, selecting, orienting and training employees; maintaining a safe, secure and legal work environment; developing personal growth opportunities Ensure validation program meets requirements of FDA (21 CFR Part 11 and Part 820), ISO 9001/13485, IEC 62304 and MDSAP Identify differences between ISO and FDA requirements and their applicability to products targeting different markets Report broadly through the organization on validation activities and instrument manufacturing audit readiness Estimate timelines and budgeting for validation engineering development efforts Formaliz

Artificial IntelligenceAIProject ManagementPmp
I
📍 California, United States
✓ High-confidence listing

$98.4K – $147.6K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Core Job Summary Position Summary: Manages the design, planning, construction and maintenance of equipment, machinery, buildings, and other facilities. Plans, budgets, and schedules facility modifications, including estimates on equipment, labor, materials and other related costs. Designs and develops organizational policies relevant to the facilities department. Oversees the coordination of building space allocation and layout, communication services and facilities expansion. May have responsibility for establishing and overseeing health and safety standards. Changes to individual responsibilities may occur due to business needs and other related duties may be assigned. Scope of Responsibilities: Receives predetermined work assignments with incremental objectives and defined processes, subject to a moderate level of control and review. Directs subordinates to complete assignments using established guidelines and procedures. Administers company policies that directly affect subordinate employees and recommends changes to unit, sub-unit, or discipline policies. Works on assignment

Artificial IntelligenceAI
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%
Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Kite is seeking a highly motivated and experienced Associate Director, Sales Analytics and Operations to join our team. The ideal candidate will play a critical role in driving sales planning and performance through data-driven insights and operational excellence. This position requires a strategic thinker with robust , hands on , ana lytical skills and a deep understanding of the biotech industry. Responsibilities include:

SQLAIExcelPower Bi
I
📍 California, Santa Clara, United States
✓ High-confidence listingCompany trend +315.4%
Quick readStrong listing-quality and freshness signals

Job Details: Job Description: The Role and Impact As a GPU Platform Hardware Design Engineer, you will play a pivotal role in designing and developing high-quality GPU hardware platforms that drive innovation in high-performance computing, graphics, and visualization technologies. You will lead the design process from initial feasibility studies through board layout, tapeout, and platform power-on, ensuring robust functionality and compatibility with industry standards. Your expertise in platform-level requirements, electrical engineering applications, and system bring-up will directly contribute to delivering cutting-edge GPU systems that accelerate Intel's leadership in computing. Business group The Data Center Group (DCG) is dedicated to advancing Intel's role in powering the digital world with leading-edge technologies. Focused on delivering innovative solutions for data center and cloud environments, DCG supports high-performance computing and graphics to enable capabilities such as AI, machine learning, and advanced visualizations. As part of the GPU IP Engineering team within DCG, you'll contribute to developing GPU systems that meet the evolving demands of the industry while supporting Intel's broader mission to create world-changing technology. Key Responsibilities - Design, develop, and evaluate electronic components, PCBs, and integrated circuits for GPU hardware platforms. - Translate platform-level requirements into detailed specifications and ensure adherence throughout the design process. - Define component placement and trace routing rules to optimize board layouts for performance, power, and signal integrity. - Conduct feasibility studies, board layout, tapeout, and platform power-on activities. - Perform functionality tests and utilize tools to verify platform configurations and compatibility. - Research, develop, and validate firmware, hardwa

Machine LearningAIRecruitment
S
📍 California, California, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Mortgage Loan Officer Subject Matter Expert Location: United States (Onshore; Remote with periodic travel) Employment Type: Full-Time About SAI Group SAI Group is a private investment firm that has committed $1 billion to incubate and scale revolutionary AI-powered enterprise software application companies. Our portfolio, a testament to our success, comprises rapidly growing AI companies that collectively cater to over 2,000+ major global customers, approaching $600 million in annual revenue, and employing a global workforce of over 4,000 individuals. SAI Group invests in new ventures based on breakthrough AI-based products that have the potential to disrupt existing enterprise software markets. SAI Group’s latest investment, JazzX, is a pioneering technology company which is building a platform that will not only shape the future of enterprise AI applications but also offer practical solutions to real-world challenges. Role Overview As JazzX’s Mortgage Loan Officer SME, you will be the single-domain authority for the front end of the mortgage business — lead intake, borrower consultation, qualification, structuring, pricing, locking, and application handoff — across product, engineering, and operations. You will own how loan officer workflows, incentives, and borrower interactions are defined, explained, and operationalized into the JazzX Mortgage Application, ensuring that AI-assisted sales and origination experiences faithfully reflect how loan officers actually work and win business. This is a hands-on position. You will work representative borrower scenarios end-to-end, document how loan officers qualify, structure, and price loans, map the lead-to-lock-to-submission journey, and sit with product managers and engineers daily to translate that knowledge into detailed product requirements, decision logic, and acceptance criteria. JazzX is bui

GitAIGoExcel
I
📍 California, United States
✓ High-confidence listing

$155.6K – $233.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Position Summary: Designs, models, and develops data management systems that integrate laboratory, operation and research data. Designs, builds, improves and maintains high performance and highly scalable data pipelines. Oversees transition of data pipelines to production and commercial settings; develops technology choices and practices that support pipeline maturation. Researches and assesses the viability of new data management and processing technologies. Scope of Responsibilities: Applies subject matter expertise and extensive knowledge of theories, practices, and design matters to lead the application of existing principles and guide the development of new ideas. Provides, guides, and uses professional concepts to resolve critical issues. Works on highly complex assignments that address future concepts where problem solving requires conceptual thinking and an evaluation of enigmatic components. Accountable for results which may impact multiple functions. Enhances formal networks with key decision makers and recognized as a thought le

Artificial IntelligenceAI
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$226.2K – $292.7K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences, Inc. is a research-based biopharmaceutical company that discovers, develops and commercialises innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead’s therapeutic areas of focus include HIV/AIDS, liver diseases, cancer, inflammation and serious respiratory conditions. For more information please visit Gilead.com An exciting opportunity has arisen within the Global Decision Sciences & Insights team for a Director, Integrated Insights for Liver & Inflammation Pipeline. Inflammation/ Liver is

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