We’re looking for a strategic operator to help advance OpenAI’s life sciences capabilities and translate them into meaningful scientific and commercial impact. Working closely with research teams and external partners, you’ll identify opportunities to improve AI models, products, and supporting infrastructure, and lead partnerships and strategic initiatives that bring these capabilities into real scientific workflows. This role combines partnership development, strategic judgment, and hands-on execution. You’ll help determine where OpenAI can make the greatest contribution, identify the expertise and resources needed, and bring together the right partners to move from an idea to demonstrated impact. In this role, you will: Shape capability priorities. Work with research and cross-functional teams to identify and prioritize new life sciences capabilities, balancing scientific value, technical feasibility, and commercial potential. Build and execute partnerships. Develop data, research, and commercial partnerships with biotechnology companies, pharmaceutical organizations, and other participants in the life sciences ecosystem. Translate capabilities into real-world applications. Partner with external organizations to apply OpenAI’s technology in scientific workflows, evaluate its usefulness, and use those learnings to inform further development. Structure effective collaborations. Work with legal, finance, research, and other teams to define partnership scope, align incentives, and navigate data access, intellectual property, commercial terms, and governance. Lead strategic initiatives. Identify and own projects that advance scientific capabilities and create long-term value for OpenAI, including licensing, joint development, and new applications of AI. Drive operational execution. Establish clear objectives, milestones, and ownership; coordinate resources; and resolve obstacles across internal teams and external partners. Expand access to expertise. Identify gaps in
Jobs in United States
Ai Systems Engineer in San Francisco
1,456 active opportunities · Updated October 2026
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Explore current ai systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.
About the Team Life sciences is one of the clearest areas where advances in intelligence can meaningfully benefit the world at large. The OpenAI Life Sciences team works at the intersection of advancing frontier life sciences model capabilities and building products to help scientists accelerate their research and leverage the full potential of AI for scientific work. Rosalind Workbench brings together the scientific tools, data sources, interactive biology file viewers and core life sciences workflows into a central environment to help scientists investigate questions, design experiments, analyze results, and advance discovery. Rosalind Workbench can be used with any OpenAI model, including GPT-Rosalind--our dedicated life sciences model, which combines frontier reasoning with specialized tool orchestration across medicinal chemistry, genomics, wet-lab assistance, and other scientific applications. Our long term vision is for teams of agents to work together across these domains, giving researchers access to broader expertise and the ability to pursue more ambitious scientific questions. About the Role We’re looking for a Product Manager to shape Rosalind Workbench for life sciences. You will own product strategy and execution, working directly with researchers in academic labs, biotech, and pharma to understand where AI can meaningfully improve their work. You’ll partner with engineering, research, design, and customer-facing teams to turn emerging capabilities into intuitive products that scientists return to. This role calls for strong product judgment, depth in life sciences, and the ability to move from an ambiguous research problem to a focused, shippable experience. In this role, you will have the opportunity to define the future of AI guided scientific discovery and build the capabilities and tools that help advance the scientific frontier for researchers and help increase the accessibility of model intelligence for scientific use. This is a chance to shape
Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. Senior Software Engineer (Federal) Secure Every Identity, from AI to Human Identity is the key to unlocking the potential of AI. Okta secures AI by building the trusted, neutral infrastructure that enables organizations to safely embrace this new era. This work requires a relentless drive to solve complex challenges with real-world stakes. We are looking for builders and owners who operate with speed and urgency and execute with excellence. This is an opportunity to do career-defining work. We're all in on this mission. If you are too, let's talk. The Okta Identity Governance Team Okta Identity Governance (OIG) is Okta's Identity Governance and Administration solution, responsible for some of the most critical and visible workflows in enterprise identity: how people request access, how approvers grant it, how entitlements are enforced, and how organizations prove to auditors that only the right people have the right access. OIG is the leading contributor to Okta's new product bookings, and it runs inside some of the largest enterprises in the world — the kind of accounts where a single tenant carries hundreds of thousands of identities across thousands of applications. OIG currently supports high-compliance public sector workloads and plans to expand our footprint to support the most secure, highly classified environments in government. The Senior Software Engineer (Federal) Opportunity As a Senior Fullstack Engineer on the OIG (Federal) team, your mission
About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made up of Sales, Solutions, Support, Marketing, and Partnership professionals who work together to bring AI to as many users as possible. About the role Our Sales team helps customers understand how highly capable AI can transform their businesses. As an Account Director, Large Enterprise, you’ll work with some of our largest accounts across a variety of industries, winning new business and expanding adoption within existing customers. This role combines technical understanding, executive engagement, and ownership of complex enterprise sales. You’ll create demand, develop opportunities, and lead deals from initial engagement through negotiation, deployment, and expansion. You’ll help executives move from curiosity about AI to a clear understanding of how it can change the way their businesses operate—and build a practical path to realizing that value. We’re looking for someone with a hunter mentality who takes initiative and creates momentum. You’re comfortable opening doors, building relationships across business units, and bringing commercial and technical stakeholders together around an enterprise transformation strategy. Success means both winning business and helping customers turn their commitments into sustained adoption and consumption. This role can be based in our San Francisco, New York City or Seattle offices. We are also considering applications to work remotely from within the U.S. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, yo
About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Our Communications team supports that mission by explaining our technology, our values, and how we safely build powerful AI. We help business leaders see what AI can make possible for their organizations, show how customers use OpenAI’s products, and explain how AI is changing the way people work. About the Role We are looking for a senior product communications leader to own OpenAI’s B2B product story across business, trade, and nontraditional media. You will lead B2B communications for major product and platform moments, translate technical capabilities into clear business value, and build a sustained editorial program grounded in customer proof. Your work will help business leaders understand the problems our products solve and the outcomes they can enable using frontier intelligence. This is an exceptionally fast-paced, hands-on role that spans every altitude of communications. You will move from setting strategic positioning and shaping executive narratives to writing launch materials, developing media pitches, and delivering the details that make a story land. Working closely with Product, Research, Marketing, Sales, and our central Product Communications team, you will identify buyer needs, substantiate our claims, and carry a clear, consistent B2B story into the market. This role reports to the Head of Business Communications. In this role, you will: Set the positioning for OpenAI’s business products, connecting new capabilities to customer needs, the work they enable, and the evidence behind our claims. Lead business storytelling for priority launches across Codex, ChatGPT Work, API and developer capabilities, agents, and other enterprise products, in partnership with central Product Communications and product owners. Build a sustained editorial program between launches, using customer stories, explainers, and executive perspectives to show how our pr
About the Team The Product Policy team develops and implements policies that shape how OpenAI’s technology is built and used. We work with teams across the company to turn complex questions about AI’s benefits and risks into practical guidance for responsible research, product development, and deployment. About the Role As Product Policy Manager, Regulation, you will map external regulatory and legislative trends and synthesize them into concrete research, product, and policy requirements. You will connect deep expertise in regulation and public policy with a sophisticated understanding of AI and strong product judgment. Your remit will span frontier AI, youth, wellbeing, use in high-stakes domains, deceptive use, and other emerging issues. Working closely with Legal and Global Affairs, you will help Product, Engineering, Research, and Safety teams understand what external developments mean for their work, what decisions or evidence are needed, and how to act. We’re looking for someone who combines deep regulatory and public-policy expertise with an in-depth understanding of AI and a demonstrated ability to advise product and engineering teams. You should be able to move from complex external developments to clear decisions and requirements that teams can implement. This role can be based in San Francisco or remote. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Map and prioritize regulatory and legislative developments across jurisdictions and AI issue areas. Distinguish enacted requirements, proposals, guidance, and emerging expectations; assess their relevance, uncertainty, timing, and implications for our models and products. Translate external developments into actionable research questions, evaluation needs, product requirements, and policy recommendations. Identify gaps in evidence, define the intended outcome and acceptance criteria, and make tradeoffs and open questions c
We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Seattle, Washington D.C., Raleigh, London, and Amsterdam. Qualifications: 7+ years of quota carrying software or technology account management experience. Strong attention to detail, organizational skills, prioritization and management of multiple cross-functional work streams across internal and external stakeholders. Executive level communication skills - written and verbal. Relationship building (understand how to leverage internal/external executives, product, etc). Strong Commercial/Sales experience (contract negotiation, value-selling). Customer retention and termination-save tactics. Desire to get technical and the ability to learn the ins and outs of Plaid's APIs. Customer empathy and deep desire to see customers succeed. Some familiarity in financial services and technical products; a high degree of intellectual curiosity. Excitement to work in a high-growth, ever-changing environment and to help build processes and tools as needed. Responsibilities: Own and manage the overall relationship with your portfolio of customers in our fastest growing customer segment. Build strong relationships with customer C-Suite, Product and Engineering teams to retain and grow revenue. Own and exceed revenue growth targets, which includes identif
🚀 About WRITER WRITER is where the world's leading enterprises orchestrate AI-powered work. Our vision is to expand human capacity through superintelligence. And we're proving it's possible – through powerful, trustworthy AI that unites IT and business teams together to unlock enterprise-wide transformation. With WRITER's end-to-end platform, hundreds of companies like Mars, Marriott, Uber, and Vanguard are building and deploying AI agents that are grounded in their company's data and fueled by WRITER's enterprise-grade LLMs. Valued at $1.9B and backed by industry-leading investors including Premji Invest, Radical Ventures, and ICONIQ Growth, WRITER is rapidly cementing its position as the leader in enterprise generative AI. Founded in 2020 with office hubs in San Francisco, New York City, Seattle, Austin, Chicago, and London, our team thinks big and moves fast, and we're looking for smart, hardworking builders and scalers to join us on our journey to create a better future of work with AI. 📐 About the role As a go-to-market (GTM) sales recruiter, you'll play a pivotal role in scaling the sales engine that powers WRITER's growth. You'll be responsible for sourcing, screening, and hiring exceptional enterprise and strategic candidates who align with our company values and contribute to our growth objectives. This is a high-impact role — the people you bring in will be the ones closing deals with the world's leading enterprises, expanding our footprint, and helping us cement our position as the leader in enterprise generative AI. We're growing fast, and our GTM team is at the center of that growth. You'll partner closely with hiring managers across sales to understand their needs, build targeted sourcing strategies, and deliver a seamless candidate experience that makes top talent excited to join WRITER. Your work will directly shape the revenue org that takes our platform to hundreds more companies. This is a 6-month contract role based in our San Francisco or New
$131.1K – $163.9K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Marketing at Brex Marketing tells the story of Brex to the world. From acquisition to activation, we translate product value into business results. Our team spans Revenue, Product, and Brand Marketing, and works closely with nearly every function at Brex. We move fast, experiment often, and think deeply about customer behavior. If you want your creativity to drive growth and shape perception, this is the place. What you’ll do As the Senior Manager, Partner Marketing at Brex, you’ll be responsible for developing and executing co-marketing strategies with key strategic and ecosystem partners. You’ll own end-to-end co-marketing programs with our partners — translating joint business plans into measurable pipeline and revenue. You will work shoulder-to-shoulder with Business Development, Sales, Product Marketing, and Brand to scale how Brex shows up with partners. Where you’ll work This role will be based in our San Francisco office. We a
$126.6K – $158.2K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Recruiting at Brex Recruiting is where every career at Brex begins. We’re the first point of connection for future builders and leaders, helping candidates see what’s possible. We partner with leaders across the company to find exceptional talent and build high-performing teams. We move quickly, think strategically, and take pride in creating a thoughtful, welcoming candidate experience from the very first contact. We don’t just fill roles, we shape the culture at Brex, finding the next generation of builders and leaders. What you’ll do As a Senior Technical Sourcer, you will be a strategic talent partner responsible for identifying, engaging, and building pipelines of world-class technical talent. You’ll collaborate closely with recruiters, hiring managers, and technical leaders to deeply understand role requirements and develop proactive sourcing strategies that fuel both immediate hiring needs and long-term growth. You’ll leverage
$240K – $300K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope out the most impactful opportunities for Brex to tackle. We are responsible for aligning cross-functional teams — such as Engineering, Legal, Compliance, and Design — on key decisions. We set strategy and drive products from inception to launch, enabling Brex to grow rapidly and help our customers reach their full potential. What you’ll do Brex has an abundance of opportunities to develop tech-enabled infrastructure and applications to drive GTM productivity, measured by pipeline dollars, conversion rates, customer activation, retention, and ultimately revenue. This role will drive key initiatives to work with a dedicated Engineering and Design team and a set of XFN partners to develop tech-enabled tooling, infrastructure, and applicati
$240K – $300K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Product at Brex The Product team is at the forefront of Brex's mission to empower employees anywhere to make better financial decisions. With a deep understanding of the business, we identify and scope out the most impactful opportunities for Brex to tackle. We are responsible for aligning cross-functional teams — such as Engineering, Legal, Compliance, and Design — on key decisions. We set strategy and drive products from inception to launch, enabling Brex to grow rapidly and help our customers reach their full potential. What you’ll do As a Staff Product Manager at Brex, you will operate at the intersection of product strategy, technical depth, and business impact. You will define and drive multi-quarter strategy within one of Brex’s most critical product domains, leading initiatives that materially shape the company’s trajectory. You will be expected to identify the highest-leverage problems, frame them with rigor, and mobiliz
$186.1K – $206.8K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex The Sales team is the driving factor behind revenue for Brex and every member of our team directly affects our bottom line. We focus on generating new opportunities, acquiring new customers, and building even stronger relationships with our current customers. Our winning culture recognizes big team wins and celebrates individual accomplishments. We ensure that top performers are recognized and have built a competitive environment to motivate and unify the team. What you’ll do As a Mid-Market Client Sales Executive II, you will play an essential role in driving revenue growth by engaging existing Brex customers and cultivating new business opportunities. In this role, you will combine your sales and relationship building skills with a strategic mindset to identify opportunities and execute strategies that recapture and increase card spend. You will have the opportunity to collaborate with cross-functional teams and learn
From $247.5K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. People at Brex The People Team at Brex keeps our company and culture growing. We’re curious, optimistic, and pragmatic, and we work across all parts of Brex to solve organizational challenges for years to come. We focus on bringing great people to the company and providing the tools and resources to empower individual and team success. Above all, we help build an authentic, inclusive environment where our team members can grow and make an impact. What you’ll do As the People Business Partner Director supporting Engineering, you will serve as a trusted partner to our CTO and Engineering leadership team, shaping the organization, leadership, and talent strategy that enables Brex to scale its technical capabilities. You will operate as a mini CPO for your client group, ensuring we are building a high-performing, durable engineering organization as we scale. Responsibilities Serve as a thought partner and advisor to the CTO and Engineerin
$167.2K – $209.1K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Marketing at Brex The Marketing team tells the Brex story — turning product innovation into customer obsession. We develop messaging, shape the brand, and bring our platform to life through thoughtful, compelling content. Our team spans Revenue Marketing, Product Marketing, and Brand Marketing, and works cross-functionally with Product, Sales, Business Development, and Design to drive growth and build trust. What you’ll do Brex is seeking a strategic, data-driven Growth Marketing Lead, Programmatic & Video to shape how we invest across programmatic display, YouTube, CTV, online video, audio, and emerging channels. You’ll own a high-impact media portfolio spanning Brand and Growth, with the opportunity to define how these programs work together, prove their incremental impact, and identify where Brex should invest next. You’ll combine deep programmatic expertise with strong measurement, audience, and experimentation instincts to tu
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