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Ai Systems Engineer in San Francisco

1,456 active opportunities · Updated October 2026

Explore current ai systems engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$192K – $240K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Engineering at Brex Engineering at Brex is about building systems that scale with speed and intention. Our teams span Software, Data, Security, and IT, and operate with high autonomy and deep collaboration. We tackle hard technical problems, own our outcomes, and push for excellence at every level — from architecture to deployment. It’s an environment where engineering is a craft, and builders become leaders. What you’ll do As a Security Operations Engineer at Brex, you will focus on preventing, detecting and responding to security threats across Brex's corporate and cloud environments. You will use existing systems and develop tools to improve our security capabilities. Our team is responsible for functions across corporate security, detection & response and infrastructure security domains; and we perform systems engineering and automation to support those functions. Security Operations is part of our wider Trust & IT o

PythonAWSAzureGCP
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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity As a Member of Technical Staff on AI Infrastructure, you will build and maintain the foundational systems and distributed infrastructure that power AI model post training, inference, and data pipelines. You will collaborate with engineering and research teams to ensure performance, scalability, and reliability of critical AI systems. What You’ll Do Design and implement large-scale, distributed AI infrastructure and services Optimize performance for GPU/xPU accelerators and cloud environments Build tools for observability, reliability, and scaling of AI workloads Partner with cross-functional teams to define AI infrastructure requirements and roadmap Contribute to architectural design and system longevity About You Have experience with GenAI infrastructure systems, distributed systems, cloud computing, and high-performance infrastructure Are proficient in programming languages like Python, Go, or similar Understand scaling challenges specific to AI workloads and accelerators Thrive in fast-paced, collaborative engineering environments The reasonably estimated base salary for this role ranges from $256,000.00 to $276,

PythonAIGoRust
P
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity As a Member of Technical Staff and AI Agent Development Lead, you will lead the design, development, and deployment of next-generation AI agents that interact with users and complex environments. You will drive the architecture and implementation of scalable, reliable AI systems, working closely with research, product and engineering teams to build safe, interpretable, and performant AI technology. What You’ll Do Lead a cross-functional engineering team focused on AI agent development, from conceptual design to production deployment. Design and implement AI agent architectures leveraging state-of-the-art language models and associated technologies. Collaborate with research scientists on scalable experiments and productize research innovations. Drive the development of agent capabilities including dialogue management, decision making, and autonomy. Ensure AI safety and alignment principles are integrated throughout the agent lifecycle. Mentor and grow technical staff, fostering an environment of collaboration and innovation. Evaluate new tools, frameworks, and methodologies to enhance AI agent capabilities. Partner

PythonMachine LearningAIGo
P
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -100%
Quick readStrong listing-quality and freshness signals

Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity As an Applied Scientist specializing in Small Language Models and AI Training, you will lead research and development efforts focused on building efficient, high-performance language models tailored for practical applications. You will work closely with research, engineering, and product teams to advance model training techniques, optimize architectures, and scale AI solutions. Your work will directly contribute to AI systems that are safe, interpretable, and impactful across diverse usage scenarios. What You’ll Do Lead research and development of novel training methodologies and architectures for small and efficient language models. Design, implement, and evaluate model training experiments to improve performance, robustness, and generalization of language models. Collaborate closely with research scientists and engineers on scalable training pipelines and model deployment strategies. Develop techniques for model compression, fine-tuning, and domain adaptation to optimize models for real-world applications. Ensure AI safety, fairness, and alignment principles are integrated into model training processes and evaluat

PythonMachine LearningAIGo
C
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why this role? We’re seeking an experienced Engineering Program Manager to join Cohere’s customer-facing Engineering Program Management team. We need someone with curiosity, drive, independence, and leadership, who has hands-on experience working directly with customers and managing projects for enterprise-grade software or enterprise-focused machine learning solutions. In return, you’ll have the unique opportunity to shape Cohere’s operations, collaborate with leading minds in the LLM space, work directly with our Strategic Customers as well as Applied ML (AML) Engineering, Forward Deployed Engineering (FDE), Platform , Product and Go-to-Market teams, and be the “technical” voice of Cohere for the customer. You will get a chance to create extremely high-impact contributions to our fast-growing company, product and culture. As an Engineering Program Manager/ Technical Program Manager, you will: Communicate: Provide clear, timely, and objective communication across the tech organization, Cohere teams, leadership, and most importantly - our strategic customers and external partners. Optimize: Break down complex issues into strateg

GitMachine LearningAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI’s mission is to ensure that artificial general intelligence benefits all of humanity. Safely delivering increasingly capable AI systems requires scalable technical safeguards, clear ownership of emerging risks, rigorous deployment readiness, and close coordination across research, engineering, product, operations, legal, policy, and external partners. Our Technical Program Managers lead complex, high-stakes initiatives that turn safety commitments into deployed systems and measurable outcomes. We work across model development, infrastructure, product, and operational response to help ensure our technology is deployed responsibly and cannot be used to cause serious real-world harm. About the Role We’re seeking Technical Program Managers to drive complex product, platform, and safety initiatives across ChatGPT, API, enterprise, and related deployment environments. These roles operate at the intersection of technical strategy and execution: you will turn safety and product priorities into actionable plans, influence architectural and operational decisions, and deliver durable capabilities across model, infrastructure, application, and platform layers. Depending on the role, you may enable sensitive or high-impact model deployments, integrate safeguards into cloud and API platforms, prevent violent misuse and other serious harms, improve detection and enforcement systems, create platform solutions for safety or establish new programs as risks evolve. You will partner deeply with engineers, researchers, product managers, and operational teams while communicating technical tradeoffs and program decisions to senior leadership. You bring technical fluency, product judgment, and a strong execution record. You’re comfortable navigating ambiguity, advocating for users and developers, balancing safety with model usefulness, and leading cross-functional work with urgency, rigor, and empathy. Specific focus areas and scope will vary by opening and level. Thi

AWSRestMachine LearningAI
P
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -72.3%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. Plaid’s Product team builds the network that powers the future of financial services. Our mission is to unlock financial freedom for everyone through open finance. Product Managers at Plaid are curious, customer-obsessed, and move quickly to deliver value. They take ownership, sweat the details, and make sound decisions with imperfect information. As a Product Manager on the AI Foundations team, you will drive Plaid’s AI strategy by building the data and intelligence layer that powers smarter financial experiences. You will work across engineering, data science, and research to develop scalable AI systems—from core embeddings and representation learning to applied model integrations that enhance developer and consumer outcomes. This role is for an experienced PM who thrives at the intersection of AI and platform products. You are technically fluent, strategic, and execution-oriented. You enjoy turning advanced machine-learning capabilities into reliable, trusted infrastructure that scales across Plaid’s ecosystem. Responsibilities AI Platform Vision: Define the strategy, roadmap, and success metrics for Plaid’s core AI and data foundation, enabling smarter, more adaptive financial products across th

C
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why this role? At Cohere, we believe in the power of multimodal AI to revolutionise the way we interact with technology. Our engineering teams push the boundaries of what's possible, and we're looking for talented individuals to join us on this exciting journey. With an exceptional ratio of compute resources to engineers, we provide an ideal environment for you to explore, innovate and shape the future of AI. July 31st 2025 - Cohere's Multimodal team Introduced Command A Vision: Multimodal AI Built for Business. At release our new flagship vision-language model: ● Consistently outperforms major models like Llama 4 Maverick, Mistral Medium/Pixtral Large, and GPT4.1 ● 83.1% average benchmark (73.5% MathVista, 90.9% ChartQA...) ● Built for the real world - 112B parameters running on just 2 GPUs ● Open weights live on HuggingFace With a focused team, breakthrough performance doesn't require breakthrough compute. Focus on the things that matter, and join the team. As a Member of Technical Staff with a focus on Multimodal AI, you will: Design and develop cutting-edge multimodal AI systems, integrating various modalities such as text,

PythonGitMachine LearningAI
C
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -79.2%

£215K – £260K/yr

Quick readStrong listing-quality and freshness signals

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! About the Role Cohere is seeking a Global Public Policy Manager to lead policy engagement on compute infrastructure, export controls, AI competitiveness, and sovereign AI strategies. Governments increasingly view AI as critical national infrastructure and are investing heavily in compute capacity, energy resources, and domestic AI ecosystems. This role will help position Cohere as a trusted partner in emerging discussions around AI infrastructure, national competitiveness, and sovereign AI deployment. Key Responsibilities Monitor and analyze developments related to AI infrastructure, data centers, energy policy, semiconductor policy, export controls, and national AI strategies. Develop policy positions on sovereign AI, compute access, digital sovereignty, and AI competitiveness. Support engagement with governments developing AI infrastructure investment programs and national AI initiatives. Collaborate with commercial, product, and corporate development teams on strategic opportunities involving public-private partnerships. Represent Cohere in policy discussions related to AI infrastructure, energy requirements, and technology c

GitRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team The Interpretability team studies internal representations of deep learning models. We are interested in using representations to understand model behavior, and in engineering models to have more understandable representations. We are particularly interested in applying our understanding to ensure the safety of powerful AI systems. Our working style is collaborative and curiosity-driven. About the Role OpenAI is seeking a researcher passionate about understanding deep networks, with a strong background in engineering, quantitative reasoning, and the research process. You will develop and carry out a research plan in mechanistic interpretability, in close collaboration with a highly motivated team. You will play a critical role in helping OpenAI ensure future models remain safe even as they grow in capability. This will make a significant impact on our goal of building and deploying safe AGI. In this role, you will: Develop and publish research on techniques for understanding representations of deep networks. Engineer infrastructure for studying model internals at scale. Collaborate across teams to work on projects that OpenAI is uniquely suited to pursue. Guide research directions toward demonstrable usefulness and/or long-term scalability. You might thrive in this role if you: Are excited about OpenAI’s mission of ensuring AGI benefits all of humanity, and are aligned with OpenAI’s charter . Show enthusiasm for long-term AI safety, and have thought deeply about technical paths to safe AGI. Bring experience in the field of AI safety, mechanistic interpretability, or spiritually related disciplines. Hold a Ph.D. or have research experience in computer science, machine learning, or a related field. Thrive in environments involving large-scale AI systems, and are excited to make use of OpenAI’s unique resources in this area. Possess 2+ years of research engineering experience and proficiency in Python or similar languages. Are deeply curious. About OpenA

PythonAWSRestMachine Learning
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team ​​Preparedness is a critical Safety Research team at OpenAI, which is focused on mitigating AI threats to global security that could scale to an extreme level of severity. Our work involves: Measurement. Monitoring and predicting the evolving capabilities of frontier AI systems. Mitigation. Keeping misuse safeguards, alignment tools, and security measures on track to adequately address extreme threats that might arise in the future. Coordination. Setting mitigation targets by maintaining OpenAI’s preparedness framework , and partnering with other staff to achieve these targets. This is urgent, fast-paced work that has far-reaching implications for the company and for society. About the role Models are becoming increasingly capable—moving from tools that assist humans to agents that can plan, execute, and adapt in the real world. As we push toward AGI, cybersecurity becomes one of the most important and urgent frontiers: the same systems that can accelerate productivity can also accelerate exploitation. As a Researcher for cybersecurity risks, you will help design and implement an end-to-end mitigation stack to reduce severe cyber misuse across OpenAI’s products. This role requires strong technical depth and close cross-functional collaboration to ensure safeguards are enforceable, scalable, and effective. You’ll contribute directly to building protections that remain robust as products, model capabilities, and attacker behaviors evolve. In this role, you will: Design and implement mitigation components for model-enabled cybersecurity misuse—spanning prevention, monitoring, detection, and enforcement—under the guidance of senior technical and risk leadership. Integrate safeguards across product surfaces in partnership with product and engineering teams, helping ensure protections are consistent, low-latency, and scale with usage and new model capabilities. Evaluate technical trade-offs within the cybersecurity risk domain (coverage, latency, model util

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team Our Safety Systems team is at the forefront of OpenAI's mission to build and deploy safe AGI, driving our commitment to AI safety and fostering a culture of trust and transparency. Within Safety Systems, the Model Policy team aligns model behavior with desired human values and norms. We co-design policy with models and for models by driving rapid policy taxonomy iteration based on data and defining evaluation criteria for foundational models’ ability to reason about safety. About the Role Frontier AI systems are rapidly expanding what is possible in cybersecurity and software engineering. These capabilities create major defensive opportunities, but they also raise serious dual-use and misuse risks across areas such as malware development, exploit discovery, vulnerability chaining, credential abuse, cyber intrusion, and autonomous offensive operations. In this role, you will help define how OpenAI’s models should behave in high-risk cybersecurity contexts. You will develop policy frameworks, threat models, taxonomies, evaluations, and behavioral specifications that guide model behavior across training, deployment, and monitoring systems. This role sits at the intersection of cybersecurity, AI safety, threat modeling, evaluation science, and policy implementation. You will work closely with research, engineering, safety training, preparedness, and product teams to build policies that are technically grounded, measurable, enforceable, and responsive to real-world cyber risk. Your Responsibilities: Design and maintain model policies for cybersecurity and frontier-risk domains, especially dual-use and high-risk cyber capabilities. Translate cybersecurity threat models into clear behavioral specifications, evaluation criteria, grading guidance, and system-level mitigations. Define practical boundaries between legitimate security research, defensive workflows, and assistance that could materially enable harmful activity. Build policy artifacts that support i

AWSGitRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the team Preparedness is a critical Safety Research team at OpenAI, which is focused on mitigating AI threats to global security that could scale to an extreme level of severity. Our work involves: Measurement. Monitoring and predicting the evolving capabilities of frontier AI systems. Mitigation. Keeping misuse safeguards, alignment tools, and security measures on track to adequately address extreme threats that might arise in the future. Coordination. Setting mitigation targets by maintaining OpenAI’s preparedness framework , and partnering with other staff to achieve these targets. This is urgent, fast-paced work that has far-reaching implications for the company and for society. About the role The stakes of securing OpenAI increases as our internal coding and research becomes increasingly driven by autonomous AI agents. Compromising these agents could allow a cyber threat actor to compromise many other parts of the company. In this role, you would lead Preparedness work defending the security of our internal AI agents against insiders, Advanced Persistent Threats (APTs), or powerful AI agents. We’re looking for a strong hands-on technical executor with experience working directly with advanced cyber threat actors. In this role, you will: Develop and maintain threat models via which advanced attackers could compromise our coding assistants and automated security systems. Identify security investments that are especially critical to make in advance; for example, prioritizing by implementation lead-times, costs, and benefit. Partner with Security, Infrastructure, Research, Legal, and Preparedness to align on implementation plans and tradeoffs. Lead technical execution directly when needed, including prototyping controls, writing and reviewing software, and coordinating engineers across teams. Work with penetration testers to close gaps in defenses. You might thrive in this role if you: Are an exceptional hands-on technical executor. Have worked with advanced

AWSRestAIRust
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -80.2%

About the Team OpenAI is building AI systems that can help professionals perform complex, high-value work with greater speed, rigor, and creativity. Investment banking is one of the most demanding environments for knowledge work: bankers must synthesize fragmented information, exercise judgment under pressure, and produce precise, defensible models, analyses, and client materials. Our team works across Research, Product, Engineering, and Go-to-Market to make OpenAI's models genuinely useful for these workflows. We translate real professional work into product requirements, evaluations, training signals, and repeatable customer solutions. We care not only whether a model can generate an answer, but whether it can deliver accurate, defensible work that experienced bankers can trust and use. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. About the Role We are looking for a Subject Matter Expert in Investment Banking to help define what excellent AI-assisted banking work looks like and turn that standard into better models and products. You will bring deep, current knowledge of how investment banking work is actually performed, including company and industry research, financial analysis and modeling, valuation, diligence, transaction execution, and the creation and review of client materials. You will use that expertise to design realistic tasks and evaluations, create and assess high-quality reference work, diagnose model failures, and help our technical teams improve model behavior and product experiences. This is a hands-on individual-contributor role for someone who enjoys both doing the work and explaining what makes it good. You should be comfortable moving between an Excel model, a presentation, a source document, an evaluation rubric, a product prototype, and a conversation with researchers or customers. You will help us distinguish outputs that merely look pl

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team The Technology Vertical team builds within Core Products. The team’s mission is to transform every major function in a technology company with AI to drive higher economic output, while people remain owners of the outcomes: setting intent, applying judgment and craft, directing iteration, and owning the result. About the Role As a Product Manager on the Technology Vertical team, you will shape how knowledge workers use AI in their daily work. You’ll craft enterprise products at the intersection of novel research capabilities and genuine enterprise needs, driving the full feedback loop from research, to product, to OpenAI’s own enterprise functions, to the broader Technology Vertical. This role is based in San Francisco, CA. We use a hybrid work model of three days in the office per week and offer relocation assistance to new employees. In this role, you will: Own the product roadmap for a line of business within tech verticals, using OpenAI’s organization to test, refine, and scale new workflows. Develop the ecosystem strategy across technology partners in your line of business You might thrive in this role if you: Have built enterprise products for non-developer knowledge workers and understand the needs of both individual contributors and organizational buyers. Can turn complex workflows, integrations, and permission requirements into clear product decisions. Are comfortable developing a strategy while working closely with engineers, customers, and cross-functional partners to ship and learn. Bring strong judgment about which vertical-specific needs should become reusable capabilities across a broader product. About OpenAI OpenAI is an AI research and deployment company dedicated to ensuring that general-purpose artificial intelligence benefits all of humanity. We push the boundaries of the capabilities of AI systems and seek to safely deploy them to the world through our products. AI is an extremely powerful tool that must be created with safety and

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