Jobs in United States

Business Systems Lead in California

57 active opportunities · Updated October 2026

Explore current business systems lead jobs in California. Filter by work mode, employment type, experience, department, date posted and distance.

I
📍 California, United States
✓ High-confidence listing

$141.6K – $212.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Summary The Staff Data Engineer is a seasoned, hands-on engineer who designs, builds, and scales data products on our cloud lakehouse, powering analytics, reporting, and AI/ML across Illumina. We are looking for someone with strong proficiency in Python, SQL, and data modeling, a solid understanding of distributed systems and system design who has built and scaled data products on modern cloud platforms such as Databricks and Snowflake. This is a hands-on, senior individual-contributor role with end-to-end ownership and leadership spanning multiple domains such as Supply Chain, Manufacturing and Quality, including mentoring engineers on our global (India-based) team. Responsibilities Partner across business, AI, and platform teams translating domain needs (e.g., SAP, Manufacturing, Quality) into well-modeled, governed and scalable data products. Design, build, and scale end-to-end data products on Databricks (and interoperating with Snowflake) — from ingestion through curated, analytics-ready datasets following a medallion (Bronze/Silver/Gold) architecture. Develop reusable frameworks, libraries, and

PythonSQLAWSGit
I
📍 California, Santa Clara, United States
✓ High-confidence listingCompany trend +315.4%
Quick readStrong listing-quality and freshness signals

Job Details: Job Description: The Role and Impact As a GPU Platform Hardware Design Engineer, you will play a pivotal role in designing and developing high-quality GPU hardware platforms that drive innovation in high-performance computing, graphics, and visualization technologies. You will lead the design process from initial feasibility studies through board layout, tapeout, and platform power-on, ensuring robust functionality and compatibility with industry standards. Your expertise in platform-level requirements, electrical engineering applications, and system bring-up will directly contribute to delivering cutting-edge GPU systems that accelerate Intel's leadership in computing. Business group The Data Center Group (DCG) is dedicated to advancing Intel's role in powering the digital world with leading-edge technologies. Focused on delivering innovative solutions for data center and cloud environments, DCG supports high-performance computing and graphics to enable capabilities such as AI, machine learning, and advanced visualizations. As part of the GPU IP Engineering team within DCG, you'll contribute to developing GPU systems that meet the evolving demands of the industry while supporting Intel's broader mission to create world-changing technology. Key Responsibilities - Design, develop, and evaluate electronic components, PCBs, and integrated circuits for GPU hardware platforms. - Translate platform-level requirements into detailed specifications and ensure adherence throughout the design process. - Define component placement and trace routing rules to optimize board layouts for performance, power, and signal integrity. - Conduct feasibility studies, board layout, tapeout, and platform power-on activities. - Perform functionality tests and utilize tools to verify platform configurations and compatibility. - Research, develop, and validate firmware, hardwa

Machine LearningAIRecruitment
DA
📍 California, United States· Full-time· Remote
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About Dawn Aerospace Dawn Aerospace is redefining space transportation through reusable, sustainable, and high-cadence flight systems. Our Aurora Spaceplane enables rapid access to suborbital space and speeds over Mach 3, serving a growing need for near-space testing, high-speed flight, and microgravity research. Together with our in-space propulsion business, Dawn is building the infrastructure for sustainable access to and operation in space. Role Overview Aurora is the first vehicle capable of flying missions to the edge of space multiple times a day. Your job is to transform this vehicle capability into mission success for our customers working from anywhere in the US - although Huntsville , USA is preferred (with domestic and international travel) . As a Mission Manager, your core role is to translate customer objectives into executable flight plans. You will be the customer’s interface to Dawn's flight operations, engineering, regulatory, and commercial teams. Throughout any project, you will coordinate the specialists required to solve individual problems while retaining responsibility for the mission. This is not a passive account-management role. You will be expected to assess mission feasibility, challenge customer assumptions, defend engineering realities, and drive clarity across complex, first-of-a-kind mission concepts. You will be the customer’s technical advocate inside Dawn, and Dawn’s operational interface to the customer. You will succeed here if you can lead through ambiguity, communicate with precision, and have the technical depth to engage meaningfully with aerospace engineers and flight operators, while keeping customers aligned, informed, and confident. Key Responsibilities Mission Ownershi

AIGoSEOProject Management
I
📍 California, United States
✓ High-confidence listing

$155.6K – $233.4K/yr

Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. Responsibilities: Drive staff results by communicating job expectations, planning, monitoring and appraising job results, coaching and counseling employees, recognizing performance issues and driving improvement, developing, coordinating and enforcing systems, policies, procedures and productivity standards Establish strategic goals by gathering pertinent business, financial, service and operations information, choosing a course of action, defining objectives, and evaluating outcomes Maintain staff by recruiting, selecting, orienting and training employees; maintaining a safe, secure and legal work environment; developing personal growth opportunities Ensure validation program meets requirements of FDA (21 CFR Part 11 and Part 820), ISO 9001/13485, IEC 62304 and MDSAP Identify differences between ISO and FDA requirements and their applicability to products targeting different markets Report broadly through the organization on validation activities and instrument manufacturing audit readiness Estimate timelines and budgeting for validation engineering development efforts Formaliz

Artificial IntelligenceAIProject ManagementPmp
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$115.3K – $149.2K/yr

Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Position Summary The Senior IT Quality Engineering Specialist serves as the technical lead for the Kite Laboratory Information Management System (KLIMS) within North America West Coast (El Segundo). This role is responsible for the operational stability, compliance, maintenance, enhancement, and technical governance of the LabVantage platform and associated integrations. The position partners closely with Quality Control, Manufacturing, Validation, Infrastructure, and Kite Business stakeholders to ensure reliable and compliant laboratory operations. Key Responsibilities System Administration & Operational Support • Provide day-to-day administration and technical support for KLIMS and related

JavaSQLRecruitment
I
📍 California, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

What if the work you did every day could impact the lives of people you know? Or all of humanity? At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients. Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible. This position maintains and repairs the facility's structure, equipment and ground, including plumbing, electrical and HVAC. Key Responsibilities: Responsible for mechanical service calls and in-house repairs throughout facility and grounds. Performs skilled trade work, such as carpentry or painting in the construction, repair or alteration of structures such as walls, roofs or office fixtures. Monitor, maintain document and perform preventative maintenance on HVAC system including central plant. May provide guidance and oversee other personnel. May work from sketches, blueprints, and drawings. Act as liaison and supervise work of contractors. Be on call and able to respond 7/24/365. Listed responsibilities are an essential, but not exhaustive list, of the usual duties associated with the position. Changes to individual responsibilities may occur due to business needs. Requirements: Requires 2-5 years of related experience Ability to continually learn through on-t

Artificial IntelligenceAI
A
📍 California, USA - Remote, United States· Remote
✓ Quality checkedCompany trend +90.9%

Job Requisition ID # 26WD97363 Position Overview We are seeking a Principal Software Engineer – Backend to join Autodesk’s Enterprise Data Management (EDM) organization within the COO-GET Engineering group. This is a senior individual contributor role operating at the Principal (P4) level , expected to drive technology direction for large, complex, and business-critical backend and distributed systems . This role is anchored in backend software engineering excellence : designing, building, and evolving scalable services, APIs, and event-driven systems that operate at enterprise scale. As a Principal Engineer, you will work with high autonomy and ambiguity , shape long-term architecture, and influence multiple teams and domains. Familiarity with data engineering concepts is valuable, but backend systems, service design, and distributed systems are the core competencies. You will function as a technical authority and force multiplier—guiding design decisions, setting standards, and ensuring Autodesk’s core data services are reliable, resilient, and evolvable over time. Responsibilities Provide principal-level technical

PythonAWSAI
S
📍 California, Virtual Address, United States
✓ High-confidence listingCompany trend +364.7%
Quick readStrong listing-quality and freshness signals

Work Flexibility: Field-based Overview As a Clinical Specialist at Stryker, you will help improve orthopedic surgeries around the world and play a direct role in our mission of making healthcare better. In this role, you will build deep clinical and technical expertise across both robotic (Mako SmartRobotics™) and manual orthopedic procedures. You will support surgeons in the operating room by assisting with pre-operative planning, case preparation, system setup, and real-time procedural workflows to ensure safe, accurate, and efficient outcomes. You will gain hands-on experience working with Mako technology—including CT-based planning, implant sizing, registration, and intra-operative support—while also developing strong competency in manual procedures, instrumentation, and OR protocols. Through shadowing experienced team members, supporting product demonstrations, and participating in labs and education programs, you will learn the systems, processes, and best practices that define world-class clinical support. This role requires adaptability, steady composure, and strong problem-solving in a fast-paced surgical environment. Because patients’ needs don’t follow business hours, you will also participate in on-call coverage, including evenings, weekends, and holidays, to ensure uninterrupted support for urgent cases and time-sensitive customer needs. What You Will Do Gain competency in solo case coverage for manual and robotic procedures through hands-on training. Assist surgeons with pre-operative CT-based planning, implant sizing, and positioning using advanced software. Support full case preparation, including instrumentation checks, equipment setup, and OR readiness. Troubleshoot technical issues confidently and efficiently in the operating room. Learn and supp

H
📍 California, United States of America, United States
✓ High-confidence listingCompany trend +103.7%
Quick readStrong listing-quality and freshness signals

Business Strategy Principal – HP Solutions Strategy – SW Description - The Opportunity Join HP’s high-impact, high-visibility HP Solutions Strategy team and help shape the future of HP Solutions across software, services, AI-enabled solutions, and emerging growth areas. This team partners closely with senior HPS leaders to define long-term direction, medium-term strategic priorities, and near-term business choices that influence portfolio strategy, planning, investment priorities, and growth opportunities. This is an exciting opportunity for a highly analytical, results-oriented strategy leader who thrives in ambiguity, enjoys solving complex business problems, and wants to make a visible impact at scale. In this role, you will help translate market, customer, technology, competitive, and financial insights into clear strategic choices—especially across software, services, vertical solutions, AI-enabled offerings, and go-to-market models. You will work across executive leaders, GBU teams, product, sales, marketing, finance, category, and cross-functional partners to develop insight-driven recommendations grounded in rigorous analysis and compelling strategic narratives. The role combines strategic problem solving with portfolio and GTM rigor, business case development, pricing and packaging support, and executive-ready deliverables for high-priority leadership discussions. If you are energized by strategic problem solving, cross-functional collaboration, and building what is next for HP Solutions, we would love to hear from you. Responsibilities Develop strategic analyses and insights that inform HP’s software, services, and solutions portfolio strategy, including market trends, customer needs, competitive dynamics, portfolio maturity, and growth op

AIProject ManagementFinance
A
📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: About Abbott Abbott is a global healthcare leader, creating breakthrough science to improve people’s health. We’re always looking towards the future, anticipating changes in medical science and technology. Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. <br /

PythonSQLPostgreSQLAWS
A
📍 California, USA - Remote, United States· Remote
✓ High-confidence listingCompany trend +90.9%
Quick readStrong listing-quality and freshness signals

Job Requisition ID # 26WD98292 Senior Art Director / Designer, Flow Studio &#64; Autodesk We are building an integrated marketing and creative team designed for how modern products grow—combining high standards, thoughtful experimentation, and a strong focus on impact. We work as One Autodesk, partnering across functions to create clear, engaging experiences that help customers understand and adopt what is next. If you are energized by creative technology, collaborative problem-solving, and the opportunity to shape how a product shows up in the world, we would love to hear from you. Autodesk builds the tools behind the world around us. From the buildings we live in to the products we use, our customers design and make what’s next, and we power that work. As we evolve into a Design and Make platform, we are creating more connected, intelligent experiences that help our customers move from idea to reality. That transformation is grounded in our One Orbit values: being Optimistic about what is possible, Relentless in pursuit of better outcomes, Brave enough to challenge convention, Ingenious in solving complex problems, Trusted in how we show up, and united as One Autodesk. Within Autodesk, Flow Studio is building a new category at the intersection of AI, creativity, and storytelling. This is an opportunity to shape how that vision comes to life through world-class design. Position Overview Flow Studio is a visual product and brand, and how it shows up matters. We need a Senior Art Director / Designer who can define and execute a modern, distinctive visual language across everything we create.<

G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$243.1K – $314.6K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Oncology Business, Strategy, and Operations Lead will play a pivotal role in supporting the SVP of Oncology Clinical Development in building and executing the strategic vision for the Oncology Therapeutic Area (TA). As Gilead Oncology enters an exciting phase of growth and investment, this position offers the unique opportunity to collaborate directly with senior leadership to advance a world-class clinical development team, build the portfolio, and elevate oncology as a key focus area for Gilead. RESPONSIBILITIES As a member of the Oncology Leadership Team help to design and facilitate

RecruitmentHR
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse
A
7 days ago
📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: Working at Abbott At Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life. You’ll also have access to: Career development with an international company where you can grow the career you dream of. Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year. An excellent retirement savings plan with a high employer contribution. Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor’s degree. A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune. A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists. The Opportunity This position works out of our Pleasanton, CA location in the Heart Failure Division. In Abbott’s Heart Failure (HF) business, we’re developing solutions to diagnose, mon

SapExcelSupply ChainWarehouse
I
📍 California, Santa Clara, United States
✓ High-confidence listingCompany trend +315.4%
Quick readStrong listing-quality and freshness signals

Job Details: Job Description: The Role and Impact As a Director, Global IT, you will play a critical role in driving complex, high-impact projects that underpin the success of Intel's technology solutions and services. You will manage end-to-end execution, overseeing project plans, resources, and timelines to deliver innovative outcomes. Your expertise will ensure seamless coordination across teams, fostering collaboration and enabling Intel to meet strategic objectives efficiently. Business Group You will join Intel's Global IT organization, a team committed to accelerating enterprise-wide innovation and operational excellence. This group is responsible for delivering technology solutions and services that empower Intel to achieve its business goals while driving efficiency and transformation across the company. Key Responsibilities - Lead large-scale technology projects and programs, ensuring alignment with business objectives, timelines, and resource allocations. - Develop detailed project plans, including scope, schedule, budget, and risk management strategies. - Manage implementation processes, including testing, documentation, training, and change control, to guarantee project success. - Collaborate across teams to assess dependencies, remove roadblocks, and address constraints impacting delivery. - Establish and drive program governance, including milestones, risk mitigation plans, and executive-level reporting. - Monitor program health metrics to ensure quality, timeliness, and adherence to project goals. - Conduct project closeout assessments and document lessons learned for continuous improvement. Qualifications: Minimum Qualifications - Bachelor's degree in Business, Engineer

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