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Lab Manager in San Francisco

51 active opportunities · Updated October 2026

Explore current lab manager jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made up of Sales, Solutions, Support, Marketing, and Partnership professionals who work together to bring AI to as many users as possible. About the role Our Sales team helps customers understand how highly capable AI can transform their businesses. As an Account Director, Large Enterprise, you’ll work with some of our largest accounts across a variety of industries, winning new business and expanding adoption within existing customers. This role combines technical understanding, executive engagement, and ownership of complex enterprise sales. You’ll create demand, develop opportunities, and lead deals from initial engagement through negotiation, deployment, and expansion. You’ll help executives move from curiosity about AI to a clear understanding of how it can change the way their businesses operate—and build a practical path to realizing that value. We’re looking for someone with a hunter mentality who takes initiative and creates momentum. You’re comfortable opening doors, building relationships across business units, and bringing commercial and technical stakeholders together around an enterprise transformation strategy. Success means both winning business and helping customers turn their commitments into sustained adoption and consumption. This role can be based in our San Francisco, New York City or Seattle offices. We are also considering applications to work remotely from within the U.S. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, yo

Artificial IntelligenceAIProcurement
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83%

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to to ship AI products. ABOUT BASE LABS Base Labs is a research lab pushing the frontier of open-source LLMs. We think intelligence should be democratized, not controlled by a handful of closed labs and we think very few teams are actually positioned to do something about that. Backed by Baseten's training and inference infrastructure, we have the compute, resources, and talent to take on hard problems at the frontier and open-source what we learn along the way. Our mission is to help build a world where intelligence isn't concentrated, but spread across an ecosystem of models that anyone can build on. That mission shapes what we choose to work on, how we work on it, and who we want in the room. We are accepting applications on a rolling basis for our first cohort of Base Labs Fellows, which is expected to start in late September. Apply using this link. BASE LABS FELLOWSHIP OVERVIEW The Base Labs Fellowship is designed to give researchers exposure to what frontier research looks like in industry. We provide funding, mentorship, and full support to our fellows, with the goal of producing rigorous, published research that shapes both the open-source ecosystem and Baseten's technical roadmap. We run multiple cohorts of Fellows each year and review applications on a rolling basis. This application is for cohorts starting in Sept 2026 and beyond. WHAT TO EXPECT 3 months of full-time research from our San Francisco office A dedicated 1:1 mentorship

Machine LearningAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team OpenAI's mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world's best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team helps customers understand, adopt, and deploy OpenAI's technology across their most important workflows. The team is made up of Sales, Solutions, Support, Marketing, and Partnerships professionals who work together to bring AI to as many people and organizations as possible. About the role As an Account Director focused on Life Sciences, you will own executive-level relationships with organizations across biopharma, medical technology, and life science services. This includes pharmaceutical and biotechnology companies, medical device and diagnostics companies, contract research organizations, contract development and manufacturing organizations, research tools companies, and laboratory or scientific services providers. This is a role for someone who understands how life sciences companies create, validate, manufacture, commercialize, and support scientific and medical products. You will help these customers evaluate and deploy OpenAI's technology to accelerate R&D, improve clinical and regulatory workflows, scale scientific and medical content operations, modernize commercial and field teams, and improve knowledge work across highly regulated environments. The role blends scientific literacy, enterprise sales discipline, technical curiosity, and relationship-driven account leadership. You will partner closely with solutions, research, product, legal, security, and compliance teams to design secure, responsible, and high-impact AI deployments for life sciences customers. This role can be remote but New York or San Francisco office locations are preferred. We use a hybrid work model of three days in the office per week and offer relocation assistance t

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI is building the infrastructure foundation for the next generation of AI. The Data Center Engineering team defines the strategy, reference architectures, technical requirements, and delivery standards for the large-scale data centers that support OpenAI research, products, and infrastructure partners. As a Data Center Infrastructure Electrical Engineer, you will help define, validate, and scale the electrical power systems that support high-density AI compute. You will translate evolving compute requirements into practical facility and rack-power architectures, evaluate new technologies and vendor solutions, and drive technical decisions across design, manufacturing validation, construction, commissioning, deployment, and operations. This role is best suited for a senior hands-on engineer with deep experience in mission-critical power systems, strong judgment under ambiguity, and the ability to connect facility infrastructure, hardware requirements, controls, telemetry, reliability, and operations. About the Role We are seeking a senior electrical infrastructure engineer to lead the development of reliable, scalable, and efficient power architectures for high-density, liquid-cooled AI data centers. The ideal candidate has strong practical experience with critical electrical systems at data centers or comparable industrial scale, including medium-voltage and low-voltage distribution, utility interfaces, backup power, UPS and battery systems, rack power delivery, grounding, protection, controls, and monitoring systems. You should be comfortable moving between long-range architecture, detailed engineering review, lab validation, vendor qualification, field deployment, and operational troubleshooting. Key Responsibilities Design and optimize electrical topologies and equipment strategies that reduce cost, accelerate schedules, improve efficiency, increase scalability, and maintain high reliability and maintainability. Review and develop basis-of-des

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the Role OpenAI's Hardware organization builds supercompute platforms from silicon and boards to full rack-scale systems to power advanced AI workloads. This role owns end-to-end quality for high-speed interconnect hardware across the product lifecycle: early design influence, supplier/contract manufacturer readiness, qualification, ramp, and fleet quality in lab and data center environments. You will be the quality lead for advanced interconnect components and assemblies, including high-speed copper cables, cable cartridges, patch panels, backplane/cable-backplane solutions, high-speed connectors, and related electro-mechanical interfaces. You will partner closely with electrical, mechanical, SI/PI, systems, reliability, operations, and external vendors to prevent escapes and drive rapid, data-driven containment and corrective action. In this role you will: Own quality for advanced interconnect components and assemblies: high-speed connectors, high-speed copper cables, cable cartridges (e.g., cable cassette style assemblies), patch panels & optics, and backplane/cable-backplane interconnect solutions. Drive quality-by-design: participate in design reviews, DFM/DFx, tolerance stacks, material and plating selections, connector mating strategy, strain relief, and assembly methods to reduce variation and field failures. Define and track quality and reliability metrics (DPPM, yield, escapes, RMA/FRACAS trends, Cpk/Ppk where applicable) for interconnects across NPI and m

AWSRestAIRust
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking a Mechanical Engineer to design, build, and own the mechanical side of our robotic actuator dynamometer and test infrastructure. You will create the test stands, couplings, fixtures, load paths, guarding, and serviceable lab hardware that enable rigorous characterization of robotic actuators. This role combines precision mechanical design with hands-on lab work. You will take robotic actuator test infrastructure from requirements and analysis through CAD, fabrication, assembly, commissioning, and iteration, partnering closely with electrical and software engineers to deliver safe, flexible, high-uptime test cells. In this role, you will Own the mechanical architecture of dynamometer and actuator test cells, including frames, bases, load paths, alignment, guarding, and serviceability. Design dynamometer structures, robotic actuator fixtures, load-motor mounts, couplings, shafts, bearings, adapters, and torque-reaction hardware. Translate robotic actuator test requirements into robust mechanical systems for torque, speed, thermal, durability, backdrive, efficiency, and failure testing. Perform first-principles analysis and simulation for stiffness, strength, fatigue, vibration, thermal growth, critical speed, and safety factors. Create precise, repeatable alignment strategies that protect test articles, load machines, sensors, and couplings. Design modular fixturing that supports rapid changeover across actuator and motor variants without compromising measurement quality. Work closely with electrical engineers on cable routing

ReactAWSRestAI
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📍 San Francisco, California, United States· Full-time· Remote
✓ Quality checkedCompany trend -83.9%

About the Team Our Robotics team is focused on unlocking general-purpose robotics and pushing towards AGI-level intelligence in dynamic, real-world settings. Working across the entire model stack, we integrate cutting-edge hardware and software to explore a broad range of robotic form factors. We strive to seamlessly blend high-level AI capabilities with the constraints of physical systems to improve peoples’ lives. About the Role We are seeking an Electrical Engineer to build and own the electrical backbone of our robotic actuator dynamometer and test infrastructure. You will design, integrate, and operate the load motor drives, power distribution, instrumentation wiring, DAQ interfaces, and safety systems that make high-performance robotic actuator testing repeatable, safe, and scalable. This role spans hands-on lab execution and system architecture: selecting and commissioning power electronics, designing robust test-cell electrical systems, bringing up sensors and DAQ, and partnering with mechanical and software engineers to turn robotic actuator hardware into trustworthy data. In this role, you will Own the electrical architecture of dynamometer and actuator test cells, from mains distribution and protection through load motor drives, braking, and auxiliary power. Specify, integrate, commission, and tune motor drives and load machines for robotic actuator torque, speed, efficiency, thermal, and durability testing. Design power distribution, grounding, shielding, cable routing, and connectorization for high-current, high-voltage, and low-level measurement systems. Integrate torque, position, speed, temperature, voltage, current, vibration, and other instrumentation from robotic actuators into DAQ and control systems. Develop electrical schematics, wiring diagrams, panel layouts, harness documentation, and test-cell interface definitions. Build, debug, and maintain test-cell electrical hardware, rapidly diagnosing noise, EMI, grounding, drive, sensor, and power-q

Artificial IntelligenceAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI's mission is to ensure that artificial general intelligence benefits all of humanity. The Consumer Devices team is building a new generation of AI-powered products that seamlessly integrate hardware and software to create intuitive, transformative experiences. We bring together experts across embedded systems, machine learning, hardware, design, and product engineering to develop products at the intersection of AI and consumer technology. About the Role OpenAI is seeking a System Performance Engineer to profile, benchmark, and optimize performance across our embedded hardware products. In this role, you will work across operating systems, applications, camera and vision, graphics, and platform teams to define product KPIs, build performance tooling, and drive optimizations from early lab characterization through product launch and real-world usage. You will help establish the performance standards that shape the user experience of our products, ensuring they remain responsive, efficient, and reliable throughout their lifecycle. This role requires deep expertise in embedded or high-performance systems, strong operating systems fundamentals, and hands-on experience debugging under tight latency, power, and memory constraints. This role is based in San Francisco, CA. We use a hybrid work model of four days per week in the office and one day working remotely. Relocation assistance is available for new hires. In this role, you will: Develop system performance benchmarks, methodologies, and policies to evaluate end-to-end product behavior. Profile and analyze performance across key product use cases and workloads using custom and industry-standard profiling tools. Partner closely with engineering teams to identify bottlenecks and drive performance optimizations across the software stack. Define high-level product KPIs and establish measurement frameworks to measure launch readiness and monitor performance throughout the product lifecycle. Measure, re

PythonAWSLinuxRest
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Cooperative AI team is scaling OpenAI with OpenAI. We are building a model powered knowledge system that evolves and learns as our products, systems and customers evolve. We leverage our state of the art models, technologies, and products (some external, some still in the lab) to assist or completely automate robust operations supporting both internal and external customers. We support OpenAI customers and internal partners globally, powering systems from customer support to integrity to product insights. We are a self-contained multi-disciplinary team, who enjoy a lightning fast feedback loop with customers at scale, some of whom sit just a few pods away. We iterate fast, and engineer for reliable long-term impact. We're constantly looking for the similarities and patterns in different types of work, and focus on building simple primitives, to apply world class knowledge to many domains. The work of this team exemplifies use of OpenAI technologies. We build systems so everyone can see the leverage that is possible with well designed AI-based implementations. We do this by working through internal use cases focused on Customers (specifically knowledge systems, automation systems, and automated agent systems) to prove impact, then we scale. About the Role We’re looking for a Backend Software Engineer to help architect and scale the infrastructure that powers our knowledge systems. This is a deeply technical and highly cross-functional role where you’ll build robust systems and backend services that serve as the foundation for how knowledge is created, accessed, and applied across OpenAI. In this role, you will: Design, build, and maintain backend services and APIs to support intelligent automation and knowledge systems Integrate and structure data across internal platforms, transforming it into formats optimized for use by downstream systems and AI workflows. Collaborate closely with product, research, and engineering teams to integrate OpenAI mode

PythonAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Cooperative AI team is scaling OpenAI with OpenAI. We are building an AI powered knowledge system that evolves and learns as our products, systems and customers evolve. We leverage our state of the art models, technologies, and products (some external, some still in the lab) to assist or completely automate robust operations supporting both internal and external customers. We support OpenAI customers and internal partners globally, powering systems from customer support to integrity to product insights. We are a self-contained multi-disciplinary team, who enjoy a lightning fast feedback loop with customers at scale, some of whom sit just a few pods away. We iterate fast, and engineer for reliable long-term impact. We're constantly looking for the similarities and patterns in different types of work, and focus on building simple primitives, to apply world class knowledge to many domains. The work of this team exemplifies use of OpenAI technologies. We build systems so everyone can see the leverage that is possible with well designed AI-based implementations. We do this by working through internal use cases focused on Customers (specifically knowledge systems, automation systems, and automated agent systems) to prove impact, then we scale. About the Role We’re looking for Software Engineers who're passionate about blending production-ready platform architecture with new tech and new paradigms. You’ll push the boundaries of OpenAI’s newest technologies to enable interactions and automations that are not only functional, but delightful. We value proactive, customer-centric engineers who can get the foundational details right (data models, architecture, security) in service of enabling great products. In this role, you will: Own the end-to-end development lifecycle for new platform capabilities and integrations with other systems Collaborate closely with engineers, data scientists, information systems architects, and internal customers to understand th

AWSRestAIRust
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team: OpenAI’s Hardware organization develops AI-native silicon and system-level solutions for the unique demands of advanced AI workloads. Building on efforts like Jalapeño, the team is developing future generations of AI-native silicon and tightly integrated systems to power the next generation of frontier models. By co-designing chips, systems, tools, and methodologies, the team helps deliver faster, more efficient, and production-ready hardware for OpenAI’s supercomputing platform. About the role: We are seeking an experienced Optical Network Engineer to lead Laser related work within our optical interconnect efforts for large-scale compute systems. The role also requires broad, hands-on optical validation experience across IM/DD-based interconnects, working from lab characterization through production readiness and scaled deployment. In this role you will: Drive laser-focused requirements and technical direction within the broader optical interconnect roadmap. Lead evaluation and validation of optical components and subsystems, including laser-based elements, in lab and production-representative environments. Support end-to-end optical testing for IM/DD interconnects (e.g., module/system bring-up, characterization, debug, and readiness for scale). Work with external partners to align on development milestones, performance targets, and quality expectations. Own technical issue triage and resolution across performance, reliability, and manufacturability topics. Collaborate across internal teams to support integration, rollout, and operational success at scale. You might thrive in this role if you have: Strong experience in laser-focused optical engineering (development, validation, manufacturing readiness, or field support). Broad hands-on background with IM/DD optical technologies and optical test/debug workflows. Experience working with external suppliers/manufacturing partners and production-oriented execution. Demonstrated ability to debug complex t

AWSRestAIRust
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📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$1.2M – $1.3M/yr

Quick readStrong listing-quality and freshness signals

About us EVERY™ is a leading VC-backed food tech ingredient company and market leader using precision fermentation to create animal proteins without the animal for the global food and beverage industry. EVERY™ is a team of passionate change-makers who are reimagining the factory farm model with a kinder, more sustainable alternative. Leveraging precision fermentation to produce hyper-functional and one-to-one replacement proteins from microorganisms, EVERY™ is on a mission to decouple the world’s proteins from the animals that make them. We are a passionate, determined (and fun!) team with a vital objective, and we're on the lookout for like-minded people to join our mission. For more information, visit www.every.com The Downstream Process Engineer II will be an integral member of our downstream process development team. You will use experimentation to optimize Every’s production process and then see the results of your changes in action at pilot and commercial-scale biomanufacturing sites. This is an excellent opportunity for someone with laboratory and tech transfer experience, who wants to make an impact at scale. What you'll Accomplish Optimize the Every downstream process via an iterative cycle. Improvements are developed in the laboratory, scaled up to an external pilot plant, and learnings are taken back to the lab for further troubleshooting and improvement. Perform various unit operations at the Every HQ such as TFF, depth filtration, chromatography, spray drying and other purification/separation processes. Develop and review tech transfer documentation to ensure successful scale up trials. Travel to external pilot plants to review the scale up of novel processes. Coordinate with third parties such as pilot scale equipment vendors to arrange internal and external trials. Partner with Every scientists and engineers to bring their bench ideas to pilot scale. Analyze results and report data to enable appropriate interpretation and

AIGoExcelHR
E
📍 San Francisco, California, United States· Full-time
✓ High-confidence listing

$900K – $1M/yr

Quick readStrong listing-quality and freshness signals

About us EVERY™ is a leading VC-backed food tech ingredient company and market leader using precision fermentation to create animal proteins without the animal for the global food and beverage industry. EVERY™ is a team of passionate change-makers who are reimagining the factory farm model with a kinder, more sustainable alternative. Leveraging precision fermentation to produce hyper-functional and one-to-one replacement proteins from microorganisms, EVERY™ is on a mission to decouple the world’s proteins from the animals that make them. We are a passionate, determined (and fun!) team with a vital objective, and we're on the lookout for like-minded people to join our mission. For more information, visit www.every.com The Role: This unique entry-level Research Associate I position offers the rare chance to work across two core teams, Analytics and Protein Science. You’ll gain hands-on experience supporting protein development, purification, and analysis, while learning how these disciplines work together to drive innovation in precision fermentation. This is a great opportunity for someone early in their career who thrives in the lab, loves variety, and wants to learn fast in a collaborative, mission-driven environment. What you'll accomplish Generate data through basic biochemistry/molecular biology techniques (including but not limited to BCA, SDS-PAGE) Operate and maintain analytical equipment (e.g., HPLC-UV/RI and Combustion Analyzer, dynamic light scatterer, FPLC-UV, fluorescence/UV plate reader) Support protein characterization workflows through lab-scale protein powder generation involving bench-scale downstream processing unit operations (microfiltration, ultrafiltration, diafiltration) Prepare samples, reagents, and buffers to support cross-functional experiments Collaborate with scientists and engineers across teams to troubleshoot and iterate quickly as part of our Design, Build, Test, and Learn pipeline Present results

AIGoLeanHR
C
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why This Role Is Different This is not a typical “Applied Scientist” or “ML Engineer” role. As a Member of Technical Staff, Applied ML, you will: Work directly with enterprise customers on problems that push LLMs to their limits. You’ll rapidly understand customer domains, design custom LLM solutions, and deliver production-ready models that solve high-value, real-world problems. Train and customize frontier models — not just use APIs. You’ll leverage Cohere’s full stack: CPT, post-training, retrieval + agent integrations, model evaluations, and SOTA modeling techniques. Influence the capabilities of Cohere’s foundation models. Techniques, datasets, evaluations, and insights you develop for customers will directly shape the next generation of Cohere’s frontier models. Operate with an early-startup level of ownership inside a frontier-model company. This role combines the breadth of an early-stage CTO with the infrastructure and scale of a deep-learning lab. Wear multiple hats, set a high technical bar, and define what Applied ML at Cohere becomes. Few roles in the industry combine application, research, customer-facing engineeri

PythonGitAIGo
C
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! Why This Role Is Different This is not a typical “Applied Scientist” or “ML Engineer” role. As a Member of Technical Staff, Applied ML, you will: Work directly with enterprise customers on problems that push LLMs to their limits. You’ll rapidly understand customer domains, design custom LLM solutions, and deliver production-ready models that solve high-value, real-world problems. Train and customize frontier models — not just use APIs. You’ll leverage Cohere’s full stack: CPT, post-training, retrieval + agent integrations, model evaluations, and SOTA modeling techniques. Influence the capabilities of Cohere’s foundation models. Techniques, datasets, evaluations, and insights you develop for customers will directly shape the next generation of Cohere’s frontier models. Operate with an early-startup level of ownership inside a frontier-model company. This role combines the breadth of an early-stage CTO with the infrastructure and scale of a deep-learning lab. Wear multiple hats, set a high technical bar, and define what Applied ML at Cohere becomes. Few roles in the industry combine application, research, customer-facing engineeri

PythonGitAIGo
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