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Lead Distinguished Machine Learning Engineer Safety in California

40 active opportunities · Updated October 2026

Explore current lead distinguished machine learning engineer safety jobs in California. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 California, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$180K – $270K/yr

Quick readStrong listing-quality and freshness signals

Lead RF Systems and Defense Engineer- HP IQ Description - Who We Are HP IQ is HP’s new AI innovation lab. Combining startup agility with HP’s global scale, we’re building intelligent technologies that redefine how the world works, creates, and collaborates. We’re assembling a diverse, world-class team—engineers, designers, researchers, and product minds—focused on creating an intelligent ecosystem across HP’s portfolio. Together, we’re developing intuitive, adaptive solutions that spark creativity, boost productivity, and make collaboration seamless. We create breakthrough solutions that make complex tasks feel effortless, teamwork more natural, and ideas more impactful—always with a human-centric mindset. By embedding AI advancements into every HP product and service, we’re expanding what’s possible for individuals, organisations, and the future of work. Join us as we reinvent work, so people everywhere can do their best work. About The Role HP IQ's Wireless Technology Team works cross-functionally with Electrical Engineering, Software, Mechanical Engineering, Product Design, Industrial Design, Program Management, and Operations to develop next-generation wearable and AI-connected products. As a Lead RF Systems & Desense Engineer, you will own the RF system architecture from concept through mass production. You will lead RF integration across Wi-Fi, Bluetooth, UWB, NFC and emerging wireless technologies while driving RF desense, coexistence, and wireless performance for highly integrated products. <span style=

H
📍 California, United States of America, United States
✓ High-confidence listingCompany trend +103.7%

$162K – $252K/yr

Quick readStrong listing-quality and freshness signals

Lead Firmware Engineer Description - Who We Are HP IQ is HP’s new AI innovation lab. Combining startup agility with HP’s global scale, we’re building intelligent technologies that redefine how the world works, creates, and collaborates. We’re assembling a diverse, world-class team—engineers, designers, researchers, and product minds—focused on creating an intelligent ecosystem across HP’s portfolio. Together, we’re developing intuitive, adaptive solutions that spark creativity, boost productivity, and make collaboration seamless. We create breakthrough solutions that make complex tasks feel effortless, teamwork more natural, and ideas more impactful—always with a human-centric mindset. By embedding AI advancements into every HP product and service, we’re expanding what’s possible for individuals, organisations, and the future of work. Join us as we reinvent work, so people everywhere can do their best work. About The Role The System Software team is responsible for firmware, operating system software, hardware-accelerated algorithms, and core developer frameworks supporting our products. We serve as the glue between our hardware teams and our higher-level software teams, and delight in finding creative solutions to complex, interdisciplinary problems as we bring our product visions to life. As a firmware engineer on our team, you will develop firmware for low-power embedded microcontrollers to coordinate sensors, ensure securi

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📍 California, United States
✓ High-confidence listingCompany trend +671.4%

$176.6K – $294.3K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY As an AI-enabled strategic scientific leader, you will partner with Oncology Research Leadership to integrate AI-driven strategies that will drive data-informed decision-making across our Oncology Research pipeline. As the AI Portfolio Lead, you will bridge cutting-edge AI/advanced analytics with deep Oncology R&D expertise to guide our portfolio strategy. Working as an individual contributor reporting into the Head, Portfolio Strategy and Program Management, you will analyze and continuously assess Oncology Research projects using AI-driven insights (predictive models, scenario simulations, competitive intelligence) and propose actionable strategies to Oncology Research Leadership. This role is science-focused and spans across discovery and preclinical stage programs, ensuring that our project teams pursue the most promising scientific approaches and mechanisms of action. Your work will directly inform pipeline prioritization and resource allocation decisions, enhancing the quality and objectivity of governance deliberations with robust data. ROLE RESPONSIBILITIES Portfolio Analysis and Insights: Continuously analyze the oncology Research portfolio (ESD through Preclinical) using advanced AI/ML tools and analytics to evaluate each program’s scientific strength, probability of success, and strategic portfolio fit per disease area strategies. Strategy Recommendation: Develop and propose data-driven portfolio strategies (at both project and portfolio levels) to senior leaders and Research governance committee. Use scenario analysis and predictive modeling to highlight optimal project prioritization, pipeline balance, and resource allocation scenarios. AI-Enabled Decision Support: Integrate AI-derived insights (e.g. machine learning predictions, knowl

Machine LearningAIRecruitment
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

Recruitment
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$195.7K – $253.2K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. The Protein Therapeutics Department is seeking a laboratory-based Automation Engineer to join the Protein Sciences team. This role will lead the design, implementation, integration and suppor

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S
📍 California, California, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Mortgage Loan Officer Subject Matter Expert Location: United States (Onshore; Remote with periodic travel) Employment Type: Full-Time About SAI Group SAI Group is a private investment firm that has committed $1 billion to incubate and scale revolutionary AI-powered enterprise software application companies. Our portfolio, a testament to our success, comprises rapidly growing AI companies that collectively cater to over 2,000+ major global customers, approaching $600 million in annual revenue, and employing a global workforce of over 4,000 individuals. SAI Group invests in new ventures based on breakthrough AI-based products that have the potential to disrupt existing enterprise software markets. SAI Group’s latest investment, JazzX, is a pioneering technology company which is building a platform that will not only shape the future of enterprise AI applications but also offer practical solutions to real-world challenges. Role Overview As JazzX’s Mortgage Loan Officer SME, you will be the single-domain authority for the front end of the mortgage business — lead intake, borrower consultation, qualification, structuring, pricing, locking, and application handoff — across product, engineering, and operations. You will own how loan officer workflows, incentives, and borrower interactions are defined, explained, and operationalized into the JazzX Mortgage Application, ensuring that AI-assisted sales and origination experiences faithfully reflect how loan officers actually work and win business. This is a hands-on position. You will work representative borrower scenarios end-to-end, document how loan officers qualify, structure, and price loans, map the lead-to-lock-to-submission journey, and sit with product managers and engineers daily to translate that knowledge into detailed product requirements, decision logic, and acceptance criteria. JazzX is bui

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A
📍 California, United States
✓ High-confidence listingCompany trend +365.2%
Quick readStrong listing-quality and freshness signals

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries. JOB DESCRIPTION: MAIN PURPOSE OF ROLE We are seeking a high caliber and ambitious Supply Chain Manager to join our team in Sylmar, CA . The Supply Chain Manager of Lifecycle Management will support the lifecycle of our product supply, including but not limited to New Product Introduction (NPI) and End of Life (EOL) product planning alignment. The lead in this role supports new product development (NPD), product transfer, and engineering projects and is responsible for managing and executing all supply chain requirements and objectives to support overall business objectives. This position provides an opportunity for key talent to develop toward future Supply Chain or Operations Leadership roles within the business. The role will have significant visibility to Senior Management and carries high expectations. This position will also have people leader responsibilities for highly skilled direct report(s). MAIN RESPONSIBILITIES Manages supply chain program/product lifecycle management processes and execution for NPD and EOL. Engages planning teams to develop demand and supply plans during the new product development and EOL processes. Engages commodity managers and buyers during the design phase (early supplier involvement) and serves as a key participant in supplier selection for the program. Coordinates material purchasing schedules and inspection releases, working closely with cross-functional supply chain and supply quality groups. Assesses EOL and last-tim

Supply ChainProcurementCustomer ServiceCRM
I
📍 California, Santa Clara, United States
✓ High-confidence listingCompany trend +315.4%
Quick readStrong listing-quality and freshness signals

Job Details: Job Description: The Role and Impact As a GPU Platform Hardware Design Engineer, you will play a pivotal role in designing and developing high-quality GPU hardware platforms that drive innovation in high-performance computing, graphics, and visualization technologies. You will lead the design process from initial feasibility studies through board layout, tapeout, and platform power-on, ensuring robust functionality and compatibility with industry standards. Your expertise in platform-level requirements, electrical engineering applications, and system bring-up will directly contribute to delivering cutting-edge GPU systems that accelerate Intel's leadership in computing. Business group The Data Center Group (DCG) is dedicated to advancing Intel's role in powering the digital world with leading-edge technologies. Focused on delivering innovative solutions for data center and cloud environments, DCG supports high-performance computing and graphics to enable capabilities such as AI, machine learning, and advanced visualizations. As part of the GPU IP Engineering team within DCG, you'll contribute to developing GPU systems that meet the evolving demands of the industry while supporting Intel's broader mission to create world-changing technology. Key Responsibilities - Design, develop, and evaluate electronic components, PCBs, and integrated circuits for GPU hardware platforms. - Translate platform-level requirements into detailed specifications and ensure adherence throughout the design process. - Define component placement and trace routing rules to optimize board layouts for performance, power, and signal integrity. - Conduct feasibility studies, board layout, tapeout, and platform power-on activities. - Perform functionality tests and utilize tools to verify platform configurations and compatibility. - Research, develop, and validate firmware, hardwa

Machine LearningAIRecruitment
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📍 California, USA - Remote, United States· Remote
✓ High-confidence listingCompany trend +90.9%
Quick readStrong listing-quality and freshness signals

Job Requisition ID # 26WD100708 Director, Expansion & Strategic Accounts D&M We are seeking a strategic Director Expansion & Strategic Accounts to lead a regional sales organization focused on the Design and Manufacturing industry. This leader will drive revenue growth, develop high-performing teams, strengthen customer and partner relationships, and execute sales strategies aligned with Autodesk’s business objectives. What You’ll Do Lead, coach, and develop a high-performing sales team focused on revenue growth and customer expansion. Develop and execute territory and industry sales strategies aligned to Autodesk priorities. Drive quota attainment through pipeline discipline, forecasting, deal inspection, and accountability. Build strong customer, partner, and internal relationships to identify growth opportunities and deliver outcomes. Partner across sales, technical sales, customer success, partner management, marketing, finance, and product teams to improve execution. Create a culture of ownership, collaboration, inclusion, and continuous improvement. What You Bring Experience leading sales teams in enterprise software, SaaS, technology, or a related B2B environment. Track record of achieving revenue targets and building predictable sales performance. Strong understanding of territory planning, pipeline generation, forecasting, account planning, and customer expansion. Experience with direct and indirect sales channels, including partner ecosystems. Ability to lead through influence across matrixed teams and senior stakeho

A
📍 California, USA - Remote, United States· Remote
✓ Quality checkedCompany trend +90.9%

Job Requisition ID # 26WD100658 Creative Director, Product & Experiences — Flow Studio (Remote) Location: Remote US or Canada | Los Angeles area preferred Organization: Flow Studio Product We’re looking for a Creative Director to help define what AI filmmaking can become with Autodesk Flow Studio. This is a rare opportunity to shape both the creative direction of the product itself and the films, experiments, demos, and cultural moments that show the world what it can do. This is an AI-first, hands-on creative leadership role embedded within the Flow Studio Product organization. You’ll have significant creative freedom, lead a dedicated content team, work closely with Product leadership, and get hands-on with emerging AI filmmaking tools and workflows. The work can range from ambitious cinematic showcases and AI films to fast-moving social experiments designed to earn attention organically. You’ll own the creative bar for everything that lives in or represents the product: the creative look and feel of key product surfaces, cinematic and animation libraries, camera moves, templates and examples, demos, launch storytelling, and other content that helps creators understand what Flow Studio can make possible. You’ll also be the primary product-side creative partner to Flow Studio Marketing, helping shape concepts, promos, launch videos, campaigns, social content, and other external storytelling. Marketing leads audience, campaign, channel, and brand strategy; this role brings the product’s creative vision, AI filmmaking expertise, cinematic taste, and product truth into the wo

G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$169.3K – $219.1K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Senior Scientist, Purification Process Development (Pivotal & Commercial) role will be responsible for leading aspects of purification development including commercial process development and process characterization for multiple biologics programs during pivotal phases (phases II/III and post-launch). In addition, this role is also expected to lead/support technology transfer, participate in purification and cross-functional initiatives, and support purification regulatory documentation. Key Responsibilities: Design experiments and demonstrate hands-on technical leadership of all aspects of purification process development including chromatography, TFF, virus f

Supply ChainRecruitment
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%
Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description The Senior Manager, Kite Safety and Pharmacovigilance provides scientific and strategic leadership for pharmacovigilance activities supporting Kite’s investigational and marketed products. This role serves as a senior pharmacovigilance science expert, leading complex safety analyses, regulatory deliverables, and cross-functional safety strategy execution. Key Responsibilities Aggregate Reporting and Medical Writing Serve as lead author for complex aggregate safety reports, including PSURs, PBRERs, and DSURs, synthesizing global safety data and clinical context Author and review high-impact safety documents supporting regulatory submissions and lifecycle management Safety Analysis and Signal Management <

Recruitment
M
📍 California, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 10 Oct 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Neuromodulation Research & Development organization develops therapies and technologies that address chronic pain and other neurological conditions. Within the Interventional Pain portfolio, teams focus on minimally invasive therapies used to treat musculoskeletal pathologies, including vertebral compression fractures, nerve pain, metastatic bone tumors, and benign bone tumors. This role supports the development of system-level verification and validation strategies for new products and enhancements across mechanical, electrical, and software components. This position is based in Santa Clara, California, and follows an onsite work model. No travel is required for this role. As a Research & Development Test Engineer, you will lead and execute verification and validation activities that support the development of interventional pain therapies and associated medical device systems. You will collaborate with cross-functional partners to define test strategies, evaluate product performance, manage technical risks, and generate evidence needed to support product development and regulatory requirements. Primary Responsibiliti

RecruitmentHR
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$169.3K – $219.1K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description At Gilead our pursuit of a healthier world for all people has yielded a cure for hepatitis C, revolutionary improvements in HIV treatment and prevention as well as advancements in therapies for viral and inflammatory diseases and certain cancers. We set and achieve bold ambitions in our fight against the world’s most devastating diseases, united in our commitment to confronting the largest public health challenges of our day and improving the lives of patients for generations to come. The Protein Therapeutics department is seeking a highly motivated laboratory-based scientist to lead the Molecular Biology function within the Mammalian Expression team. In this capacity

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