Become a part of our caring community You have shipped AI products before. You understand the difference between a demo and a production system. You have strong opinions about evaluation frameworks because you have experienced the consequences of operating without them. You are at your best when you own architecture decisions while continuing to build and deliver critical code yourself. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to source documents, and route complex cases to human experts. The output of these systems supports healthcare decisions that impact real members. As a Lead AI Applied Engineer, you will provide technical leadership for AI-enabled products and platforms, define architectural direction, establish engineering standards, and personally design and build the most critical components of our systems. You will lead through both technical expertise and execution, helping the team deliver reliable, scalable, and auditable AI solutions in a highly regulated healthcare environment. Why Join Us Lead the architecture of production AI systems where LLMs are foundational to the product experience. Make key technical decisions regarding model selection, system boundaries, platform architecture, and build-versus-buy strategies. Own the highest-risk and highest-impact technical challenges involving reliability, explainability, and correctness. Influence engineering culture and establish standards that shape how the team builds and ships AI products. Work on systems operating at meaningful scale, processing millions of documents and supporting healthcare decisions across a large member population. Partner
Jobs in United States
Lead Engineering Manager in United States
2,559 active opportunities · Updated October 2026
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15 jobs
Explore current lead engineering manager jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.
About the Team OpenAI’s User Operations team shepherds our customer’s adoption of AI and ensures that our customers' product experience is nothing short of exceptional. We are building the very first post-AGI support team. We resolve complex issues, provide technical guidance, and support customers in maximizing value and adoption from deploying our products. We work closely with Sales, Technical Success, Product, Engineering and others to deliver the best possible experience to our customers at scale. OpenAI's customers represent a range of diverse backgrounds and maturity, from early-stage startups to established global enterprises. About the Role We are looking for a leader to build and scale our Support Engineering team, which will collaborate directly with our strategic enterprise accounts, our product and engineering teams, as well as our field teams to solve some of the most difficult technical problems faced by our customers. You will lead one of the best technical troubleshooting teams at OpenAI, and our customers and Engineering teams will look to you for technical guidance in addressing the most technically difficult issues in our environment. You will play an integral role in building knowledge within the team and be part of strategic initiatives for organizational and process improvements. Working directly with our most strategic customers - You will be crucial to the success of the most innovative, disruptive, and high-scale AI solutions being built with the OpenAI platform. This team will handle high difficulty situations and issues. The team will be global, providing 24x7 technical coverage for our customers. This will be an opportunity to build this new team from first principles - your leadership will determine the future of this organization. The ideal candidate will have a combination of technical capabilities mixed with strong leadership and systems building strength. This role is based in San Francisco, CA. We use a hybrid work model of 3 days
Become a part of our caring community Humana is seeking a Lead Cloud Architect – NoSQL Databases to provide strategic leadership, architecture direction, and engineering oversight for enterprise NoSQL database platforms across Humana’s cloud environments. This role will focus on the design, implementation, modernization, and governance of NoSQL database solutions, including MongoDB, Azure Cosmos DB, Neo4j, and vector database technologies. The successful candidate will help define and advance Humana's enterprise NoSQL strategy, support platform rationalization initiatives, and ensure database solutions are secure, scalable, resilient, automated, and aligned with enterprise architecture standards. This role requires hands-on technical depth, strong cloud architecture experience, and the ability to collaborate across security, engineering, quality, application, and business teams. Key Responsibilities Develop, document, and maintain enterprise-wide NoSQL database standards, reference architectures, design patterns, and best practices. Lead architecture and engineering efforts for NoSQL platforms including MongoDB, Azure Cosmos DB, Neo4j, and vector databases. Support NoSQL platform rationalization and modernization initiatives, including migration planning and execution from Cosmos DB to MongoDB where appropriate. Architect secure, highly available, scalable, and performant NoSQL database solutions across cloud environments, including Azure and/or Google Cloud Platform. Define database architecture patterns for document databases, graph databases, key-value workloads, and vector search use cases. Guide application teams on NoSQL data modeling, partitioning, indexing, query patterns, performance optimization, and operational readiness. Oversee automation of NoSQL provisioning, configuration, monit
From $213K/yr
Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog’s Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company’s interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Support Datadog’s AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem. Attend meetups, conferences, and ecosystem events to expand Datadog’s visibility and pipeline opportunities. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog’s AI roadmap. Support negotiation processes, including term sheets and partnership structures. Collaborate on integration planning with cross-functional partners after acquisitions or strategic de
Work Flexibility: Remote As a Senior Lead, Data Engineering, you will serve as a technical leader who helps shape the future of enterprise data solutions. In this role, you will drive complex data initiatives, influence technical strategy, and partner with teams across the organization to build scalable, high-impact data products. This is an opportunity to solve challenging business problems while mentoring fellow engineers and elevating data engineering best practices. What You Will Do Lead the architecture, development, and modernization of scalable enterprise data platforms that support global procurement analytics and business transformation. Define and help execute a multi-year data engineering strategy focused on platform scalability, reliability, automation, technical debt reduction, and long-term maintainability. Design, build, and optimize Azure-based data solutions using technologies such as Databricks, Delta Lake, Azure Data Factory, Azure DevOps, CI/CD pipelines, and infrastructure automation. Integrate and harmonize data across multiple ERP systems by standardizing supplier, purchasing, and master data into common enterprise data models. Partner with procurement analysts, architects, engineers, and business stakeholders to translate complex business needs into reusable, scalable data products and engineering solutions. Establish engineering standards, conduct architecture reviews, improve documentation, and mentor engineers to raise the overall technical capability of the team. Identify and implement AI-enabled approaches that accelerate development, improve data quality, automate documentation, support testing, and enhance analyst productivity. Evaluate and recommend tools, frameworks, patterns, and platform investments that improve performance, reliability, security, governance, and operational ef
About the Team OpenAI’s 1P Hardware Systems team operates at the intersection of Hardware Engineering, Infrastructure, Supply Chain, Manufacturing, Deployment, and Finance to translate infrastructure demand into an executable systems plan. The Planning Lead connects system demand and deployment timing to site and configuration requirements, power availability, XPU needs, hardware supply commitments, manufacturing capacity, and site readiness. About the Role OpenAI is seeking a 1P Hardware Systems Planning Lead to own the integrated demand, supply, and deployment plan for our 1P AI infrastructure systems. This role will connect infrastructure demand and site power availability to system configurations, XPU requirements, and hardware supply commitments—creating a single, actionable view of whether our deployment plan can be met. You will establish the planning mechanisms that allow teams to see what changed, understand the impact, and act quickly when demand, supply, configuration, site readiness, or power timing moves. You will work across Hardware Engineering, Infrastructure, Supply Chain, Manufacturing, Deployment, Finance, and external partners to identify gaps early and drive recovery plans to closure. This is a highly cross-functional role for someone who combines systems-level thinking, strong analytical judgment, and rigorous program execution. The ideal candidate can turn complex and changing inputs into a clear operating plan, surface the decisions that matter, and drive accountability across teams without relying on formal authority. Success also requires strong communication judgment: the ability to align cross-functional teams, brief leadership at a concise and decision-oriented level, and go deep into the underlying assumptions, dependencies, risks, and recovery plans when needed. In this role, you will: Own the integrated planning process for 1P hardware systems, connecting system demand, deployment timing, site and configuration requirements, power ava
From $170K/yr
Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog's Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company's interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Support Datadog's AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem through meetups, conferences, and events. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog's AI roadmap. Support negotiation processes, including term sheets and partnership structures, and collaborate on integration planning with cross-functional partners after deals close. Help attract early-stage AI companies into Datadog's startup program. Wh
Our Purpose Mastercard powers economies and empowers people in 200+ countries and territories worldwide. Together with our customers, we’re helping build a sustainable economy where everyone can prosper. We support a wide range of digital payments choices, making transactions secure, simple, smart and accessible. Our technology and innovation, partnerships and networks combine to deliver a unique set of products and services that help people, businesses and governments realize their greatest potential. Title and Summary Lead Workday Engineer - Integrations and Extend Overview The P&C Engineering team designs, develops, and implements technology solutions that improve and engage Mastercard employees across the globe. • Do you enjoy building enterprise applications that solve complex business challenges at global scale? • Do you have a passion for architecting innovative Workday solutions that improve employee experiences? • Do you thrive in environments where modernization, automation, AI, and continuous improvement are strategic priorities? • Can you connect business strategy with technical architecture and guide engineering teams toward the right solution? This role serves as a Lead Integration Engineer, responsible for architecting enterprise applications, modern employee experience, and scalable platform capabilities. You will lead the evolution of Mastercard's Workday platform through Workday Extend, AI, automation, APIs, and modern application development. Role • Lead the architecture, design, development, testing, implementation, documentation, and support of enterprise applications using Workday Extend. • Architect scalable solutions leveraging Workday Extend, Orchestrate, APIs, Studio, Core Connectors, EIBs, and Workday Web Services. • Design reusable application frameworks, s
Lead Systems Integrator Company: The Boeing Company Boeing Defense, Space & Security (BDS) is seeking a Lead Systems Integrator (Level 4) to support an Air Dominance Fixed Wing Proprietary Program in St. Louis, MO . Step into a fast-paced, cutting-edge program where your expertise will drive the design, integration, and testing of advanced, cloud-based systems that empower mission planning, debrief, and tactical Command & Control (C2) solutions for fixed-wing platforms. In this role, you will lead the development, analysis, and integration of innovative engineering solutions for critical Ground System capabilities and ensure seamless support for ground systems from initial design through to final delivery. You will partner closely with the team’s test lead as well as the overall chief integrator who oversees all activities related to design, integration, and test. You will work with a high-performing, cross-functional team in an agile environment, driving next-generation capabilities from design through delivery. This role offers the chance to innovate with open-architecture, model-based designs and collaborate across disciplines to support critical defense missions. You champion best practices, processes, and standards for the integration team, mentor systems and electrical engineers, and coach solution leads on execution. If you’re passionate about advancing mission-critical systems and thrive in a collaborative, fast-moving environment, this is your opportunity to make a significant impact. Position Responsibilities Lead team of systems and electrical engineers in behavior modeling and requirements decomposition for system, sub-system, and software design
Lead Analyst Company: The Boeing Company Boeing F-22 Mission Systems team is hiring for a Lead Analyst located in Berkeley, MO . As Lead Analyst, you will be responsible for analyzing engineering solutions for the F-22 Raptor, including both enhancing existing field units with the addition of new capabilities as well as architecting and testing completely new systems. In this role you will be joining a cross-functional team to progress our products through the development lifecycle. Position Responsibilities: Leads analysis and translation of complex requirements into system architecture, hardware and software designs and interface specifications. Must be able to work in a fast-paced, collaborative environment, engaging with multiple teams and being responsive to agile requirements and critical path customer need dates. Collaborates with Responsible Engineers, customer technical staff, suppliers, and Lockheed Martin teammates to develop and document complex electronic and electrical system requirements for F-22 avionics sub-systems and weapon system architecture Analyzes and translates requirements into system architecture, hardware and software designs and interface specifications in support of lab and operational environments Reviews test data, including off-nominal data, for accuracy, quality and/or fidelity prior to delivery to customer This position is expected to be 100% onsite. The selected candidate will be required to work onsite at one of the listed location options. This position requires the ability to obtain a US Secret Security Clearance for which the US Government requires US Citizenship A final Secret Clearance
Become a part of our caring community Job Description Summary The Lead Solutions Architect provides architecture leadership for CenterWell Home Health programs and platforms, shaping conceptual and reference architectures, governing solution designs, and aligning delivery teams to cloud and data strategies. The scope includes high-priority initiatives as well as interoperability and provider-data integrations that span CenterWell and Humana Insurance. As Lead Solution Architect, you'll be the senior individual contributor on a team with broad accountability across CenterWell's dispensing pharmacy portfolio — mail order, specialty, retail, and associated platforms. You'll own the architectural vision for complex, multi-system initiatives, shape how technology decisions get made, and act as a connective force between business strategy, engineering execution, and enterprise standards. You will operate within CenterWell IT – Cross-CenterWell Architecture. You will collaborate with product, engineering, EA Activation, security, data, and operations. You will engage governance forums to enable Integrated Health across CenterWell and Humana Insurance. Key Activities Quickly conduct structured knowledge transfer with existing architects and relevant stakeholders to capture critical in-flight designs and decisions. Review current initiatives and establish an architectural roadmap aligned with organizational priorities. Develop or refine reference architectures and design patterns for core platforms and solutions. Collaborate with governance and compliance teams to validate designs against enterprise standards and regulatory requirements. Define integration strategies and solution blueprints for key systems and data flows. Establish architecture review processes and decision forums to support de
About the Team OpenAI is building the next generation of advertising for an AI-powered world. As AI changes how people discover information, explore possibilities, and make decisions, we believe this presents a huge opportunity for small and medium-sized businesses to connect with customers in new ways. The SMB Ads Marketing team is building this opportunity from the ground up. We define how businesses discover OpenAI’s advertising platform, become successful advertisers, and grow their investment over time. Working closely with Product, Ads Engineering, Data Science, and Sales, we combine customer insight, rigorous experimentation, and fast execution to turn early opportunities into scalable growth. About the Role We are hiring a Lead, Ads Prospecting & Growth Intelligence to build the intelligence and orchestration platform powering OpenAI’s ads business. This person will help us identify the right companies and people, understand why they are relevant, determine the right next action, and learn from what happens afterward. Own the prospecting function for the ads business, serving SMB Ads while building a foundation reusable across segments. Set the vision, operating model, roadmap, platform choices, business rules, adoption, and outcomes; and partner with Ads Engineering, Data Science, and internal platform teams. Decide what to build in-house, enable through internal platforms, or deliver through selected vendors and partners. In This Role, You Will Lead the function’s strategy, roadmap, operating model, and adoption. Connect platform investments to measurable advertiser and business outcomes. Define a unified prospect, account, contact, and advertiser data model. Establish standards for identity, data quality, provenance, freshness, confidence, and consent. Combine market, intent, behavioral, product, CRM, campaign, and customer-success signals to improve targeting and customer engagement. Design enrichment and verification workflows. Evaluate in-house cap
Become a part of our caring community Join a high-impact leadership role at the forefront of healthcare transformation. As the Lead Enterprise Architect, you will shape the future of technology across a complex and rapidly evolving healthcare ecosystem spanning payer, provider, pharmacy, clinical, corporate, and digital technology domains. This is an opportunity to influence enterprise-wide strategy, drive modernization at scale, and partner directly with executive leadership to deliver innovative, secure, and resilient technology platforms that improve business outcomes and healthcare experiences. You'll collaborate with senior tech domain leaders, product and engineering teams, infrastructure organizations, and cybersecurity stakeholders to define modern architecture standards, accelerate innovation, and enable scalable enterprise capabilities across the organization. We're looking for a strategic technology leader who combines deep architecture expertise with strong business acumen and healthcare industry knowledge. The ideal candidate is passionate about solving complex enterprise challenges, influencing organizational direction, and building future-ready platforms that balance agility, performance, security, and operational excellence. You will report to an Associate Director of Enterprise Architecture. The Lead Enterprise Architect is responsible for defining enterprise-wide technology strategy and architecture standards. These standards and modernization roadmaps apply across a complex healthcare ecosystem, which spans payer, provider, pharmacy, clinical, corporate, and tech domains. Additionally, the Lead Enterprise Architect governs digital transformation initiatives. This role partners with executive leadership, product teams, engineering organizations, infrastructure teams, cybersecurity, and business stakeholders to drive enterprise architect
From $525.5K/yr
Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. Senior Director, Generative AI About the Role Roblox Build is our generative creation product, the platform where creators design, build, and publish 3D experiences. We are looking for a Senior Director of Generative AI to lead the Applied AI organization inside Build, responsible for turning state-of-the-art foundation models into high-quality, reliable creation systems at Roblox scale. This leader will own the full applied AI stack: model strategy and routing, model adaptation and fine-tuning, code generation (CodeGen), 3D layout generation (LayoutGen), and the evaluation science and infrastructure that tells us what actually works. You Will Own model strategy and routing for Build. Design and build an intelligent model layer that selects the right model for each creation task based on quality, capability, latency, cost, and safety, leveraging both frontier models and Roblox-adapted open-source models. Lead model adaptation across the Applied AI org, including fine-tuning, distillation, synthetic data generation, human feedback pipelines, and preference optimization for Roblox-specific creation tasks such as Luau code generation and 3D scene understanding. Drive CodeGen capabilities
From $154K/yr
Location Details: At GoDaddy the future of work looks different for each team. Some teams work in the office full-time; others have a hybrid arrangement (they work remotely some days and in the office some days) and some work entirely remotely. This is a remote position, so you’ll be working remotely from your home. You may occasionally visit a GoDaddy office to meet with your team for events or meetings. Join Our Team GoDaddy's Global Storage Engineering team operates one of the largest Ceph environments in the world, delivering the object, block, and file storage platforms that power GoDaddy's hosting infrastructure, internal services, OpenStack environments, and next-generation AI/HPC workloads. If you're passionate about distributed systems, storage architecture, and solving failure scenarios at massive scale, this is an opportunity to work on infrastructure few engineers will experience in their careers. Ceph is a strategic platform at GoDaddy — not an ancillary service. Our global footprint includes 80+ production clusters, 20,000+ OSDs, 1,830 storage nodes, 300 PB of raw capacity, and 69 billion objects spanning five datacenters across three continents. The platform supports RBD, RGW (S3/Swift), and CephFS workloads through more than 1,550 pools, 574,000 placement groups, and 900+ MDS daemons, creating engineering challenges that demand deep expertise in storage architecture, data durability, performance optimization, automation, and observability. As a Lead Senior Site Reliability Engineer, you'll serve as one of the principal technical leaders for GoDaddy's Ceph platform. You'll design the next generation of storage clusters, lead major platform upgrades, drive capacity and hardware strategy, and establish the standards that govern how the platform scales. You'll be the engineer the team turns to for the most complex s
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