Jobs in United States

Lead Enterprise Systems Engineer in New York

350 active opportunities · Updated October 2026

Explore current lead enterprise systems engineer jobs in New York. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 New York, New York, United States· Full-time
✓ High-confidence listing

From $1.7M/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. The Senior Manager, Operations Program Strategy will build and lead the operating system that enables CLEAR’s field organization and Aviation leadership team to execute consistently and scale effectively. You’ll own the standards, program governance, strategic planning, initiatives organization, and change management that connect Central Operations with the field—ensuring programs are ready before launch, priorities stay aligned, and change lands successfully across all Aviation programs. What you'll do: Drive Central Operations strategic planning and rhythms of business, including OKRs, program management, Monthly Business Reviews, annual planning and budgeting, and cross-functional strategic initiatives Build and lead CLEAR’s Operations change management and field communications framework, ensuring changes are thoughtfully planned, clearly communicated, appropriately sequenced, and consistently executed across a distributed field organization and leadership team Define and maintain CLEAR’s field operating standards, including SOPs, role expectations, quality assurance frameworks, and accountability measures across the field organization Lead program governance for Operations, establishing clear stage gates, readiness criteria, launch requirements, feedback loops, and field intake processes that enable successful execution of new programs and initiatives Serve as the integration point across Aviation programs, aligning cross-functional stakeholders and sequencing field-facing priorities to create a consistent operating experienc

GitRestAIGo
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📍 New York, New York, United States· Full-time
✓ High-confidence listing

From $65K/yr

Quick readStrong listing-quality and freshness signals

Overview: Guidepoint’s Business Development teams are passionate about expanding our reach with both new and existing clients. We support all of Guidepoint’s service offerings, helping to build relationships and communicate how Guidepoint helps clients stay informed and make better business decisions. Our teams are motivated to provide custom offerings designed to help every potential client make the most of their partnership with Guidepoint. Guidepoint is seeking qualified candidates for a role as Business Development Associate on the US Corporate Growth team. This person will report directly to the SVP, Corporate Client Growth as they secure new relationships with our target client base. This is a hybrid position out of our New York City office. What You’ll Do: Develop a working knowledge of industry coverage and the competitive landscape. Partner with management to identify top-tier new business opportunities based on strategic business development criteria and targets. Conduct outbound prospecting to generate leads and lead introductory/exploratory calls with prospects Meet designated sales targets using a strategic and thoughtful process designed to partner with clients and add value to their process Onboard new users effectively Work closely with the client service team to collect feedback on open and closed projects What You Have: Bachelor's degree from an accredited college/university Broad base knowledge of the sales process from lead generation to relationship management Excellent communicator capable of handling high-profile clients Demonstrated ability to work in a team atmosphere A desire to work in a fast-paced entrepreneurial environment Initiative and ability to handle increasing responsibility over time Excellent written and verbal communication skills AI fluency and experience using AI-enabled tools to support research, organization, prioritization, and written communication Ability to use AI-enabled tools thoughtfully an

N
📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -40%
Quick readStrong listing-quality and freshness signals

About Us: Small businesses are the backbone of the US economy, comprising almost half of the GDP and the private workforce. Yet, big banks don’t provide the access, assistance and modern tools that owners need to successfully grow their business. We started Novo to challenge the status quo—we’re on a mission to increase the GDP of the modern entrepreneur by creating the go-to banking platform for small businesses (SMBs). Novo is flipping the script of the banking world, and we’re excited to lead the small business banking revolution. At Novo, we’re here to help entrepreneurs, freelancers, startups and SMBs achieve their financial goals by empowering them with an operating system that makes business banking as easy as iOS. We developed modern bank accounts and tools to help to save time and increase cash flow. Our unique product integrations enable easy access to tracking payments, transferring money internationally, managing business transactions and more. We’ve made a big impact in a short amount of time, helping thousands of organizations access powerfully simple business banking. Why Novo? Novo is a rapidly growing series B fintech startup with a mission-driven team that’s passionate about helping every small business in America Positive, inclusive, supportive culture cheering you on your journey We work with very new technologies and architecture patterns Offices in NYC and India. Role Summary: We're looking for a Procurement Analyst to own the day-to-day operations of Novo's third-party risk management (TPRM) and procurement process end to end. You'll be the person who keeps every vendor request moving chasing down documents, following up with stakeholders, and making sure nothing falls through the cracks between Legal, InfoSec, Compliance, and the business teams who requested the vendor in the first place. This is a hands-on, individual contributor role for someone who's comfortable being the connective tissue across a lot of moving parts. You'll take full own

AIGoRustFinance
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $192K/yr

Quick readStrong listing-quality and freshness signals

Coordination Systems provides foundational distributed systems building blocks for internal Datadog platforms. Our services cover sharding, consensus, resource protection, configuration distribution, and much more. We are looking for a manager to lead the Coordination Systems - Storage team. This team provides essential configuration storage and distribution systems that are depended upon by almost every service and pod at Datadog. We power critical runtime configuration (e.g. feature flags), complex control planes (e.g. dynamic sharding configuration), and much more. Storage is one of four subteams within Coordination Systems. If successful, the candidate will have opportunities to lead other growing and impactful areas such as Resource Protection. At Datadog, we place value in our office culture - the relationships that it builds, the creativity it brings to the table, and the collaboration of being together. We operate as a hybrid workplace to ensure our employees can create a work-life harmony that best fits them. What You’ll Do: (Describe role responsibilities here/max 6 bullets) Lead a core team of 5 engineers (distributed, with majority in NYC) Lead ceremonies, prioritize and delegate project Stay hands-on with the code, e.g. isolated features, small remediations, investigation follow ups Stay actively involved in operations, incidents, root cause analysis, etc. Constantly promote a culture of operational excellence, organizing gamedays, conducting operational reviews, staying proactive with reliability Who You Are: (Describe role qualifications here/max 6 bullets) Strong distributed systems skills, able to understand and account for a variety of failure modes, well-versed in end-to-end o11y, validation testing, simulation setup, etc. Worked on platform teams before, providing critical infrastructure to internal stakeholders Experienced in handling significant incidents, both as a responder and follow-up ow

AIRustExcelSEM
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 New York, NY, United States· Full-time
✓ High-confidence listing

$120K – $150K/yr

Quick readStrong listing-quality and freshness signals

Biohub is the first large-scale initiative bringing frontier AI models, massive compute, and frontier experimental capabilities under one roof. We're building a general-purpose system to accelerate scientific discovery, integrating frontier AI models, biological foundation models, and lab capabilities, with the ultimate goal of curing disease. Our technology powers scientists around the world, translating AI capabilities into tools that accelerate research everywhere. The Team The Chan Zuckerberg Biohub New York is an independent nonprofit research institute that brings together three powerhouse universities - Columbia University, The Rockefeller University, and Yale University - into a single collaborative technology and discovery engine. Biohub itself supports some of the brightest, boldest engineers, data scientists, and biomedical researchers to investigate the fundamental mechanisms underlying disease and develop new technologies that will lead to actionable diagnostics and effective therapies. We are guided by our values of scholarly excellence; disruptive innovation; hands-on engineering/hacking/building; partnership and collaboration; open communication and respect; inclusiveness; and opportunity for all. Our Vision We pursue large scientific challenges that cannot be pursued in conventional environments We enable individual investigators to pursue their riskiest and most innovative ideas The technologies developed at Biohub facilitate research by scientists and clinicians at our home institutions and beyond Diversity of thought, ideas, and persp

RestMachine LearningAIGo
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $80K/yr

Quick readStrong listing-quality and freshness signals

The GTM Strategy & Operations Associate will join a global team driving Datadog’s next phase of growth. We’re interdisciplinary thinkers leveraging diverse business backgrounds in tech, management consulting, investment banking and business development to accelerate Datadog’s global growth. We work directly with Datadog’s most senior leaders to set corporate strategy, improve efficiency across the business, support data-driven decision-making, own complex operations, and more. In this role, you will identify opportunities for revenue growth and design strategic go-to-market (GTM) initiatives by evaluating business tradeoffs and partnering with senior leaders to shape GTM strategy. You will drive key planning processes, including capacity planning and quota planning, optimization and expansion strategies, and KPI design and measurement. Additionally, you will lead critical operational initiatives and long-term strategic projects that improve execution and help build the foundation for the company's continued growth. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What you’ll do: Strategic roadmap development: Develop short- and long-term GTM strategies by identifying growth opportunities, setting business priorities, and aligning sales and growth targets. Lead strategic planning initiatives, including headcount and KPI planning, incentive design, and cross-functional projects to improve execution and accelerate revenue growth. Global quota ownership: Own quotas for the global Sales organization – build and maintain quota models, adjust them throughout the year in response to org changes, and drive stakeholder alignment along the way. GTM analysis, reporting, and modeling: Analyze sales and GTM data to identify trends and understand efficiency by channel. Develop data

PythonSQLAIGo
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 New York, Pearl River, United States
✓ Quality checkedCompany trend +68.8%

$176.6K – $294.3K/yr

POSITION SUMMARY You will be responsible for managing the clinical sample logistics function for Pfizer’s vaccine clinical portfolio, ensuring samples are transported safely, compliantly, and reliably across domestic and international clinical trial networks to the Pearl River, NY biorepository and then distributed to our network of internal and external testing laboratories. You will lead an end-to-end logistics strategy from study start-up through operations and finally sample disposition. Your responsibilities include leading a large team, improving global logistics capabilities, advancing digital and automation initiatives, and partnering with Vaccines, Quality, Legal, Finance, Compliance, clinical study teams, couriers, and technology vendors. You will be accountable for maintaining sample integrity, enabling global clinical trial execution, and developing scalable logistics processes to support Pfizer’s vaccine pipeline. KEY RESPONSIBILITIES Lead the global sample logistics function--Provide strategic and operational leadership for a team of 40+ colleagues responsible for domestic and international shipment execution, study start-up support, ongoing operations, and clinical sample lifecycle management. Shape long-term sample logistics strategy. Develop scalable operating models, governance frameworks, and business continuity plans that support pipeline growth, clinical trial expansion, and evolving global regulatory expectations. Protect sample integrity and compliance. Ensure reliable, temperature-controlled movement of clinical biological samples while maintaining adherence to applicable FDA, EMA, IATA, DOT, CDC, trade compliance, GCLP, and Pfizer quality requirements. Advance inspection readiness and quality oversight. Maintain robust documentation and audit-ready processes for deviation management, CAPAs, change controls, an

AIProject ManagementFinanceSupply Chain
D
📍 New York, New York, United States
✓ Quality checkedCompany trend -88.9%

The Technical Solutions (TS) Enablement team empowers Datadog's global post-sales organization—including Support, Customer Success, and Sales Engineering—with the skills, tools, and resources they need to deliver world-class customer outcomes. As a Senior TS Enablement Program Manager supporting Sales Engineering , you'll own the design and execution of complex, high-visibility enablement programs that drive lasting change across the TS organization. You'll operate with significant autonomy, lead cross-functional initiatives, and serve as a senior voice within the Enablement team—partnering closely with leadership to translate business priorities into measurable enablement impact at scale. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own the end-to-end strategy and execution for complex, global enablement programs—managing multiple concurrent workstreams across regions, functions, and timelines with limited guidance. Lead cross-functional stakeholder relationships with senior partners across StratOps, Product, TS Leadership, and the People Team—negotiating scope, aligning on priorities, and driving accountability without positional authority. Translate business goals and OKRs into multi-quarter program roadmaps; communicate priorities, trade-offs, and progress to leadership with clarity and a clear point of view. Design and implement comprehensive metrics frameworks to measure change adoption and program effectiveness; pull and analyze Salesforce and LMS data to track performance against KPIs; present findings to senior stakeholders and iterate for lasting impact. Build and deliver executive-ready materials that tell a compelling business story—translating complex data, program updates, and regional insights into structured narratives with clear

AISalesforce
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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -83%

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to to ship AI products. ABOUT THE ROLE As a Event Marketing Manager, you will lead the development and execution of regional marketing strategies to support sales goals, drive demand, and enhance brand awareness. This role requires a strategic thinker with a builder mentality that has a strong understanding of the New York tech ecosystem. RESPONSIBILITIES Develop and execute regional field marketing plans and programs to align with sales priorities and pipeline goals. Plan and manage events to drive demand, accelerate pipeline, and engage customers. Own program management, including event logistics, budget oversight, and vendor coordination. Analyze and report on campaign effectiveness, providing insights to optimize future initiatives. Collaborate with product marketing to align messaging and go-to-market strategies with field initiatives. Prioritize seller requests by expected revenue. Represent Baseten at industry events and build brand presence in-market. QUALIFICATIONS Bachelor’s degree in Marketing, Business, or related field. 5-7 years of experience in field marketing in the technology or SaaS industry. Proven track record in delivering and optimizing demand generation programs to meet pipeline goals. Strong understanding of sales processes. Proficiency with marketing tools such as Salesforce & Hubspot. Excellent project management skills with the ability to prioritize and execute multiple initiatives simultaneously. Collaborativel

Machine LearningAIGo
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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -40%

About Us Small businesses are the backbone of the US economy, comprising almost half of the GDP and the private workforce. Yet, big banks don’t provide the access, assistance and modern tools that owners need to successfully grow their business. We started Novo to challenge the status quo—we’re on a mission to increase the GDP of the modern entrepreneur by creating the go-to banking platform for small businesses (SMBs). Novo is flipping the script of the banking world, and we’re excited to lead the small business banking revolution. At Novo, we’re here to help entrepreneurs, freelancers, startups and SMBs achieve their financial goals by empowering them with an operating system that makes business banking as easy as iOS. We developed modern bank accounts and tools to help to save time and increase cash flow. Our unique product integrations enable easy access to tracking payments, transferring money internationally, managing business transactions and more. We’ve made a big impact in a short amount of time, helping thousands of organizations access powerfully simple business banking. Why Novo? • Novo is a rapidly growing series B fintech startup with a mission-driven team that’s passionate about helping every small business in America • Positive, inclusive, supportive culture cheering you on your journey • We work with very new technologies and architecture patterns • Offices in NYC and India Role Summary The Senior Manager, Customer Support & Success is the strategic owner of Novo's most critical 1:1 customer touchpoints - from complex escalations and collections recovery to a proactive customer success motion you’ll get to build from scratch. This is a player-coach role: you will lead a small, high-performing team while staying close to the work yourself. You will operate with significant autonomy, bring consistency and customer obsession, and shape what this function looks like two to three years from now. About the Role Escalations & Collections — Raise th

ReactAIGoRust
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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -40%

About Novo Small businesses are the backbone of the US economy, comprising almost half of the GDP and the private workforce. Yet, big banks don’t provide the access, assistance and modern tools that owners need to successfully grow their business. We started Novo to challenge the status quo—we’re on a mission to increase the GDP of the modern entrepreneur by creating the go-to banking platform for small businesses (SMBs). Novo is flipping the script of the banking world, and we’re excited to lead the small business banking revolution. At Novo, we’re here to help entrepreneurs, freelancers, startups and SMBs achieve their financial goals by empowering them with an operating system that makes business banking as easy as iOS. We developed modern bank accounts and tools to help to save time and increase cash flow. Our unique product integrations enable easy access to tracking payments, transferring money internationally, managing business transactions and more. We’ve made a big impact in a short amount of time, helping thousands of organizations access powerfully simple business banking. Why Novo? Novo is a rapidly growing series B fintech startup with a mission-driven team that’s passionate about helping every small business in America Positive, inclusive, supportive culture cheering you on your journey We work with very new technologies and architecture patterns We provide learning and development budgets to help you grow and bond with your team Offices in NYC and India The Role We're looking for a Senior Designer / Art Director to own the creative vision across our marketing surfaces—paid, owned, and everything in between. You'll be the person who makes Novo look and feel like the brand it aspires to be, translating business goals into campaigns that stop thumbs, convert prospects, and make our existing customers proud to bank with us. This is an individual contributor role with real influence. You won't manage a team, but you'll shape how the entire company shows up

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📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -100%

What we're building Mutiny is the self-improving AI infrastructure for GTM teams to execute faster and close more revenue. Our ambition is to do for revenue velocity what Cursor and Claude Code did for engineering velocity. With Mutiny, everyone in sales and marketing gets a bench of GTM athletes that handle any work across their revenue motion and learn from what's actually moved their deals. In April we re-launched the product as an agent-first platform. Anthropic showcased us as a leader in AI GTM. MRR is growing more than 70% month-over-month, with customers like Uber, Rippling, and Snowflake. We're backed by Sequoia, YC, and Insight, and we're building a generational company. The opportunity Most post-sales leaders inherit a process. You'll build it. As our AI strategist lead, you'll own Mutiny's managed account book and lead the technical solutions function that backs up our most complex customers. The teams running Mutiny (Rippling, Uber, Snowflake, Zendesk, and Gusto) are betting hard on AI, and they need post-sales partners who move their roadmap forward, not just their renewal date. You'll set the bar for what great support looks like, build the playbooks that let CS scale, and step into people management as we hire AI strategists underneath you. This role is in person in New York City. The teams running Mutiny (Rippling, Uber, Snowflake, Zendesk, and Gusto) are betting hard on AI, and they need post-sales partners who move their roadmap forward, not just their renewal date. They don't need a partner who tracks their renewal date; they need one who moves their roadmap forward and shows them what's possible with the product before they ask. You'll set the bar for what great looks like, build the playbooks that let CS scale, and grow into people management as we hire AI Strategists underneath you. This role is in person in New York City. What you'll own The managed book. Onboarding, adoption, retention, and expansion across every managed account at Mutiny. T

RestAIGoRust
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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $116K/yr

Quick readStrong listing-quality and freshness signals

The Technical Solutions (TS) Enablement team empowers Datadog's global post-sales organization—including Support, Customer Success, and Sales Engineering—with the skills, tools, and resources they need to deliver world-class customer outcomes. As a Senior TS Enablement Program Manager supporting Global Support Engineering, you'll own the design and execution of complex, high-visibility enablement programs that drive lasting change across the TS organization. You'll operate with significant autonomy, lead cross-functional initiatives, and serve as a senior voice within the Enablement team—partnering closely with leadership to translate business priorities into measurable enablement impact at scale. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Own the end-to-end strategy and execution for complex, global enablement programs—managing multiple concurrent workstreams across regions, functions, and timelines with limited guidance. Lead cross-functional stakeholder relationships with senior partners across StratOps, Product, TS Leadership, and the People Team—negotiating scope, aligning on priorities, and driving accountability without positional authority. Translate business goals and OKRs into multi-quarter program roadmaps; communicate priorities, trade-offs, and progress to leadership with clarity and a clear point of view. Design and implement comprehensive metrics frameworks to measure change adoption and program effectiveness; pull and analyze Salesforce and LMS data to track performance against KPIs; present findings to senior stakeholders and iterate for lasting impact. Build and deliver executive-ready materials that tell a compelling business story—translating complex data, program updates, and regional insights into structured narratives with cle

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $192K/yr

Quick readStrong listing-quality and freshness signals

We are the Experimentation team at Datadog, a startup operating inside one of the fastest-growing companies in software. The team brings together engineers who joined through Datadog’s May 2025 acquisition of Eppo with engineers from across Datadog, and together we are building feature flagging and experimentation into the platform. Both products were recently launched this year, and we are just getting started: we are migrating customers from Eppo onto Datadog while shipping an ambitious roadmap across both flagging and experimentation. Our statistics engineers hold PhDs and are pushing the boundaries of what an experimentation platform can do. Our full-stack engineers move fast, lean on the latest AI tooling, and prototype and ship new features weekly. We talk to customers directly to shape requirements, and our roadmap is driven by our own product vision and sharpened by real customer and sales input. We are looking for an Engineering Manager to lead the team building the Experimentation App. You will own one to two squads to start, partnering closely with our engineers, statisticians, product managers, and designers to turn a deep roadmap into a shipped product. To conform to US export control regulations, candidates should be eligible for any required authorizations from the US government. What You’ll Do: Lead, mentor, and grow a team of strong full-stack and frontend engineers. Help them grow to the next level and continuously provide them opportunities to develop. Own delivery for the Experimentation App from planning through production, balancing speed with quality in a fast-paced environment. Set technical direction in partnership with your team and our statistics engineers, engaging credibly on architecture and tradeoffs. Partner with Product, Design, and customers directly to shape requirements and turn customer and sales input into roadmap. Foster a culture of fast iteration and high engineering standards through code reviews, design reviews, and blamele

AIGoRustSpring
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $192K/yr

Quick readStrong listing-quality and freshness signals

Applied AI is where Datadog's ambitious AI bets get built and shipped ( Bits Chat , updog ). We sit at the intersection of research and product: turning promising capabilities from Datadog AI Research lab and the research community into production systems that reach real customers. The team builds the foundations for agentic systems capable of operating at scale in complex production environments. Current bets span agents that run autonomously at scale, context and memory layers that make those agents more intelligent over time, and tools that help customers build and validate AI-native services in production. The mandate is to move fast from idea to customer impact, and when a product finds its footing, to set it up for growth. As an Engineering Manager I in Applied AI, you will lead a team of engineers and applied scientists working on one of these challenges. You will define technical direction, run short feedback loops, make deliberate decisions about what to pursue or stop, and work closely with product managers, research teams, and cross-functional partners to ship AI capabilities that matter. At Datadog, we place value in our office culture, the relationships and collaboration it builds and the creativity it brings. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do Lead and develop a team of engineers and applied scientists focused on building the foundations for agents operating at scale Work closely with product managers, research teams, and cross-functional partners to shape the team's bets from initial framing through to broader adoption, with a clear definition of success criteria at each stage Own end-to-end delivery of high-quality AI systems, from early research exploration to production-grade reliability, with high standards for operational excellence, system reliability, and technical quality Navigate the unique challenges of shipping AI-powered products: balancing quali

Machine LearningAIGoRust
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