Jobs in United States

Lead Enterprise Systems Engineer in United States

2,624 active opportunities · Updated October 2026

Explore current lead enterprise systems engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team The Product & Platform teams at OpenAI are responsible for delivering the company’s most impactful offerings—such as ChatGPT, our API platform, and new enterprise capabilities—to a global and diverse customer base. These systems must perform at scale and deliver exceptional experiences to developers, consumers, and businesses alike. Technical Program Managers at OpenAI play a key leadership role in scaling these efforts, partnering deeply with product, engineering, design, and go-to-market teams to bring ambitious ideas to life and ensure clarity and discipline in execution. About the Role We are hiring a Technical Program Manager to support OpenAI's critical AI deployments across strategic cloud partners. This role is designed for a candidate who can operate as an end-to-end owner across internal engineering teams and external partner organizations. This role will drive the technical strategy and execution required to bring OpenAI models and platform capabilities into partner environments responsibly and at scale. The work spans engineering deliverables, shared roadmaps, model launch pipelines, technical integration, launch readiness, and post-launch follow-through. You will work closely with senior leaders across OpenAI engineering, infrastructure, product, safety, security, legal, finance, and go-to-market, as well as technical counterparts at our partners. The job is to turn broad partnership commitments into concrete execution plans, align both sides on what must land, and build repeatable mechanisms for launching OpenAI capabilities on third-party platforms. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead end-to-end execution for major cloud partner programs spanning model deployment, product integration, operational readiness, launch follow-through, and partner-platform adoption. Own integrated technical roadma

AWSRestAIGo
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s mission is to ensure that general-purpose artificial intelligence benefits all of humanity. The Identity team builds the foundational systems that enable people, organizations, devices, and agents to securely access OpenAI products. The team works across consumer and enterprise experiences, including account structures, sign-in, authentication, recovery, privacy, permissions, administration, and agent identity. As AI systems become increasingly capable of acting on behalf of people and organizations, we are defining new models for authorization and trust across human-to-agent and agent-to-agent interactions. About the Role In this role, you’ll lead design for foundational identity experiences across OpenAI’s products. You’ll make permissions, access, risk, and administration feel clear, safe, and genuinely usable—whether someone is securing a personal account, administering access across an enterprise, signing in to another product with ChatGPT, or authorizing an agent to perform sensitive work. Your work will span established identity challenges and emerging interaction models without established design conventions. You’ll help define how users understand what an agent can access, who or what it is acting on behalf of, and when confirmation or stronger authentication should appear. Working closely with product, engineering, security, privacy, and design, you’ll translate complex policies and technical systems into coherent, trustworthy experiences. This role is based in our San Francisco HQ. We offer relocation assistance to new employees. In this role, you will: Lead the design direction for identity, account security, permissions, and administrative experiences across OpenAI’s consumer and enterprise products. Design and ship high-quality experiences spanning sign-in, authentication, account recovery, device accounts, privacy, access controls, governance, and remediation. Define mental models and interaction patterns for human-to-agent and

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

Technical Program Manager – Applied Product & Platform About the Team The Product & Platform teams at OpenAI are responsible for delivering the company’s most impactful offerings—such as ChatGPT, our API platform, and new enterprise capabilities—to a global and diverse customer base. These systems must perform at scale and deliver exceptional experiences to developers, consumers, and businesses alike. Technical Program Managers at OpenAI play a key leadership role in scaling these efforts, partnering deeply with product, engineering, design, and go-to-market teams to bring ambitious ideas to life and ensure clarity and discipline in execution. About the Role We’re seeking a Technical Program Manager to drive complex, large-scale product and platform initiatives across ChatGPT, API, and related surfaces. This role sits at the intersection of technical strategy and execution. You’ll be responsible for translating product vision into actionable plans, shaping interfaces and experiences from both consumer and developer perspectives, and ensuring successful delivery across web, mobile, and platform layers. You’ll bring deep technical fluency, product sense, and a strong execution track record. You’re comfortable managing ambiguity, influencing architectural direction, advocating for developers, and leading cross-functional delivery with discipline and empathy. Location: San Francisco, CA (Hybrid – 3 days/week in-office) In this role, you will: Collaborate with product, engineering, and design to shape roadmaps, technical strategies, and long-term platform direction. Translate product vision into clear, scalable technical execution plans, balancing short-term delivery with long-term platform evolution. Lead end-to-end execution of cross-functional product and platform programs—from planning through launch and iteration. Own timelines, milestones, dependency management, risk mitigation, and accountability across teams. Partner with engineering teams to influence ar

AWSRestAIGo
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📍 United States· Full-time
✓ Quality checkedCompany trend -92.7%

At Vanta, our mission is to help businesses earn and prove trust. We believe that security should be monitored and verified continuously, and we empower companies to practice better security and prove it with ease. Vanta has a kind and talented team, and while some have prior security experience, many have been successful at Vanta without it. Vanta is hiring for a Head of Design (VP) to lead our design organization — setting direction for a ~40-person team, shaping the next generation of AI-native product experiences, and building the quality systems that let great design ship at scale. The Design team at Vanta shapes how security and compliance teams experience Vanta — from a startup founder building their security program for the first time to an enterprise security team managing hundreds of controls. The org spans all areas of Vanta — GRC, Trust, Platform, Self-serve, and AI — and includes product designers, visual designers, design engineering, content designers, and a user researcher, led by experienced design directors. As AI fundamentally changes what products can do and how they get built, this team is at an inflection point: the right leader will define what it means for a design org to be genuinely AI-forward — enabling designers to move faster, ship more, and contribute to product direction and delivery in new ways. This is the right role for a design leader who leads with AI fluency, brings strong taste and craft across interaction design and visual design, and has the operational instincts to build the systems that make quality a consistent property of the whole org. What you’ll do as Head of Design at Vanta: Lead a team of ~40 designers and design directors across GRC, Trust, Platform, Self-serve, and AI — setting org-wide direction and enabling each leader to do their best work Lead the team building the next generation of agentic, AI-native product experiences — defining what great design looks like as Vanta’s products are increasingly shaped by AI E

RestAIRust
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📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 Overview We are looking for a strategic, hands-on leader to own ClickUp's organic growth engine at the forefront of the AI Search era. You will bring deep SEO fundamentals, but this is not a traditional Director role. The landscape has shifted, and this position is responsible for defining ClickUp's acquisition strategy across modern discovery systems, building the team and workflows to execute it, and setting the standard for how brands show up across AI-powered surfaces. Our goal is to lead in AI visibility, backed by real investment, executive buy-in, and the autonomy to move fast. You will own how ClickUp is discovered across Google, ChatGPT, Perplexity, and emerging answer engines. You'll translate market shifts into focused strategy, build AI-powered systems that multiply your team's output, and influence cross-functional partners across Engineering, Content, Product Marketing, and Analytics to rally behind organic growth. This role is equal parts strategist, operator, and pioneer. The Role Own ClickUp's organic acquisition strategy across Google Search, LLMs, communities, review platforms, and emerging discovery surfaces, evolving it for an agentic and LLM-first landscape. Build AI-powered workflows and agents to automate everything from content creation to complex analytical assessments, championing experimentation and AI-first ways of working. Build and manage strategic external partnerships (AI platforms, review ecosystems, third-party publishers) and guide internal teams across Reddit, G2, YouTube, etc. to maximize ClickUp's organic presence. Partner closely with Engineering, Performance Mar

AWSMachine LearningAIGo
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📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 As Senior Manager, CX Operations at ClickUp, you will own strategy, execution, and operational leadership for Technical Account Management (TAM) Operations , spanning Professional Services and Customer Success. Partnering closely with TAM leadership, you will serve as the day-to-day operational leader for the systems, automation, planning, quality, and insights that power our Services & Success organization. You will set the operating rhythm and performance standards for TAM Operations while owning the AI agent harness and automation layer within your domain. You will shape the cadence of business for TAM, unlock data insights, coach organizational performance, transform internal capabilities, and influence strategic decisions across Services, Success, and cross-functional leadership. You will architect, ship, operate, and iterate on AI-driven workflows that enhance and automate customer health inspection, engagement management, services delivery, quality measurement, and decision support across TAM and CX. About the Role Strategy & Operations Own the vision and strategy for delivering world-class customer experience through our Services & Success operating model Drive cross-functional alignment across Sales, Product & Engineering, Finance, and Support by synthesizing customer health, retention, and services delivery opportunities into operational priorities Lead and execute strategic initiatives to optimize and transform customer engagement, services delivery, and internal collaboration processes Extract key business insights from qualitative and quantitative data, identify risks and o

AWSMachine LearningAIGo
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📍 United States· Full-time
✓ High-confidence listingCompany trend -99%

From $212K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Difference You Will Make: Airbnb is entering a new era—reimagining how fraud, safety, and quality are measured, protected, and elevated across the digital landscape. Reporting to the Director of Advanced Analytics, Fraud & Safety, you will lead a dispersed team of ~8 advanced analysts tasked with turning safety measurement into governed, self-serve decision systems for Policy, Ops, Legal, Product, and Engineering. You will be a pivotal leader safeguarding Airbnb’s global community. You’ll steer a multidisciplinary team that designs, delivers, and scales state-of-the-art analytics for: Safety (physical & digital) Connected-account & circumvention detection Privacy protection & risk management This role isn’t just about reporting what happened; it’s about building the systems that help Airbnb see around corners. You will democratize data access, build always-on scenario simulators for fraud and safety, and turn incident impacts into seamless signals for continuous improvement. Your insights and systems will empower every stakeholder—from legal to operations, policy to product—to make bold, data-driven, and context-aware decisions in real time. A Typical Day: Own end-to-end analytical workflows for platform safety controls: data ingestion, feature engineering, modeling, experimentation, and visualization. A core mandate is to co-own and drive the enterprise-wide “Safety Single Source of Truth” (SSoT) strategy —a unified, structured data asset and taxonomy that underpins decision-making across Product, Operations, Policy, and Legal. Ensure metrics are future-proof, privacy-compliant, and g

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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team The Corporate Development team sits at the intersection of OpenAI’s strategy and the global AI ecosystem. Partnering closely with research, engineering, product, GTM and business leaders, we analyze markets, technologies, and companies to identify opportunities that accelerate OpenAI’s mission and long-term strategy. Bringing together expertise in strategy, M&A, and integration, the team leads the end-to-end process of sourcing, evaluating, negotiating, and integrating acquisitions and other strategic transactions. About the Role This is a high-visibility, strategically critical, cross-functional role at the intersection of M&A execution, enterprise go-to-market, and operational excellence. You will lead the critical phase from diligence through integration planning and post-close follow-through, define repeatable integration playbooks, and partner directly with senior stakeholders to ensure each transaction delivers intended value. The ideal candidate brings structured, hands-on integration experience, with particular expertise in enterprise / B2B transactions and a passion for AI, including building an AI-native corp dev platform. This role is based in our San Francisco HQ. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead integration planning and strategic execution for acquisitions from diligence through post-close follow-through, with clear owners, milestones, risks, and decision points. Translate deal rationale into practical integration goals and plans across product, engineering, sales, partnerships, customer success, people, finance, legal, security, systems, and communications. Partner with deal leads during evaluation and diligence to assess integration considerations, including tech stack, talent assessment, GTM alignment, transaction structure, operational readiness, and execution risk. Advise sponsors on how best to bring onboard acquisitions

AWSRestAIGo
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the team OpenAI’s mission is to build safe artificial general intelligence (AGI) which benefits all of humanity. This long-term undertaking brings the world’s best scientists, engineers, and business professionals into one lab together to accomplish this. In pursuit of this mission, our Go To Market (GTM) team is responsible for helping customers learn how to leverage and deploy our highly capable AI products across their business. The team is made of Sales, Solutions, Support, Marketing, and Partnership professionals that work together to create valuable solutions that will help bring AI to as many users as possible. About the role As an Account Director focused on Healthcare, you will own executive-level relationships with leading healthcare organizations, including integrated delivery networks (IDNs), health systems, academic medical centers, health insurers, digital health companies, and healthcare technology providers. You’ll help these organizations safely and effectively deploy OpenAI’s technology to improve clinical and administrative workflows, enhance patient and provider experiences, automate operational processes, and accelerate enterprise-wide AI adoption. This role blends enterprise sales expertise, technical depth, business acumen, and relationship-driven selling. You will collaborate closely with researchers, engineers, and healthcare-focused solution strategists to design secure, compliant, and high-impact AI deployments. This role is based in San Francisco. We use a hybrid work model of three days in the office per week and offer relocation assistance to new employees. In this role, you’ll: Manage a focused portfolio of large healthcare provider, payer, and healthcare technology accounts, developing long-term strategic account plans. Lead complex, multi-stakeholder sales cycles spanning clinical, operational, IT, digital transformation, and executive leadership teams. Partner with Solutions and Research Engineering to design pilots that demon

AWSGitRestAI
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s mission is to ensure the responsible and widespread adoption of artificial intelligence. In support of that mission, the Marketing team helps deeply understand customer audiences and market dynamics, influence the development of the right products, build sustainable and customer-aligned monetization models, and drive awareness, adoption, and usage across OpenAI’s products and platform. We take a data-driven approach to understand markets, develop monetization strategies, and uncover customer needs that shape product strategy and messaging. We partner closely with Sales, Partnerships, Product, Engineering, Research, Comms, and Design to deliver a cohesive end-to-end customer experience and lead go-to-market efforts for new product launches across channels. About the Role As a Product Marketing Manager, Research & Safety , you will shape how the world understands OpenAI’s frontier research and our approach to developing AI responsibly. You will establish the strategic narrative for some of the company’s most important research themes—including frontier capabilities, safety, preparedness, reasoning, and compute—and translate complex technical work into clear, credible stories for researchers, policymakers, and the broader public, working with cross-functional teams to translate that messaging and reach developers and enterprise. Working closely with Research, Safety Systems, Policy, Communications, and Product teams, you’ll lead the go-to-market strategy and messaging for major research and safety initiatives. You’ll develop narratives that build trust, translating technical concepts into tangible artifacts and messaging, drive industry understanding of emerging evaluation frameworks, and help communicate OpenAI’s unique perspective on responsible frontier AI development. You’ll also identify creative and non-traditional ways to bring these stories to the audiences that matter most. In this role, you will: Establish the strategic narrative f

AWSRestAIGo
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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83%

ABOUT BASETEN Baseten powers mission-critical inference for the world's most dynamic AI companies, like Cursor, Notion, OpenEvidence, Abridge, Clay, Gamma and Writer. By uniting applied AI research, flexible infrastructure, and seamless developer tooling, we enable companies operating at the frontier of AI to bring cutting-edge models into production. We're growing quickly and recently raised our $1.5B Series F , led by Altimeter Capital, Conviction Partners, and Spark Capital. Join us and help build the platform engineers turn to to ship AI products. THE ROLE As the Head of IT at Baseten, you will build, scale, and secure our internal technology function to support our rapid growth. Reporting to our Chief Information Security Officer, you will lead and mentor a team of 5+ IT engineers, leading the charge to transition Baseten from startup-era IT to a highly automated, enterprise-ready IT organization. You will take full ownership of corporate IT infrastructure, Helpdesk operations, corporate identity management, device lifecycles, and vendor procurement. As we scale to support the world’s most dynamic AI companies, you will ensure our internal systems scale seamlessly with our headcount, providing a secure, frictionless, and world-class technology experience for all Baseten employees. RESPONSIBILITIES Team Leadership: Manage, mentor, and grow a team of IT engineers, fostering a high-performance culture focused on technical excellence and end-user satisfaction. Helpdesk Operational Excellence: Build a fast-response support function by establishing clear response SLAs, tracking employee satisfaction metrics, and formalizing on-call and incident response processes. Zero-Touch Automation: Architect and implement automated employee onboarding, offboarding, and role-based access changes through deep integrations across HRIS, MDM, and IAM systems. SaaS Management & Procurement: Establish comprehensive SaaS management processes to eliminate shadow IT, automate access w

Machine LearningAIGoRust
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📍 United States· Full-time
✓ Quality checkedCompany trend -95.9%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies - from the world’s largest enterprises to the most ambitious startups - use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone's reach while doing the most important work of your career. About the team Stripe’s Design organization builds the product and brand experiences that millions of businesses and developers rely on. We’re a cross-functional, global organization of product designers, content designers, design researchers, design systems engineers, motion designers, and design program specialists. Our mission is to make economic infrastructure simple and accessible. Design plays a central role by making complex flows understandable, crafting clear product language, and building consistent systems that scale. The Design Operations team leads Design’s business operations, runs cross-organizational programs, and builds the systems that help teams collaborate and produce high-quality work. Design Program Managers guide complex programs through the design lifecycle and apply design thinking to our operating model. They prototype and iterate on how our team works. We’re looking for a Design Program Manager to partner with the Research team. This full-time role reports to the Head of Design Operations. What you’ll do Responsibilities Lead and build programs for the Research organization. Develop and implement processes and resources that support impactful research and scale the use of user insights across Stripe. Improve our operating model and processes, including automating tasks, improving workflows, and developing repeatable methodologies. Measure the impact of these changes. Prepare researchers to use agentic workflows, including des

AIGoMarketingFigma
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📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -90.5%

From $185K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu We are seeking a Senior SOX Manager to lead enterprise-wide programs focused on SOX compliance, IT controls, and controls transformation across modern technology environments. This role sits at the intersection of technical program management, digital risk, and engineering, requiring the ability to translate complex system architectures into scalable, audit-ready control frameworks. The Senior SOX Manager will own program strategy and execution, driving alignment across Engineering, Finance, Data, and Audit stakeholders to deliver automated, efficient, and sustainable control environments. What you'll cook up in your first year Program Strategy & Execution Lead end-to-end SOX programs, including planning, execution, and delivery across ITGCs, ITACs, and key business process controls Drive risk assessments, control scoping, te

AWSAzureGCPCI/CD
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📍 Louisville, Cayman Islands, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community We are seeking a highly experienced Lead Full Stack Engineer to drive engineering excellence across front-end, back-end, API, and data layers. This role is responsible for setting technical direction, ensuring consistent delivery across teams, and aligning engineering solutions with business priorities. The ideal candidate will be a strong technical leader who thrives in complex environments, drives modernization initiatives, and develops high-performing engineering talent. This role offers the opportunity to shape the future of our engineering landscape, influence enterprise-scale decisions, and lead transformation initiatives that directly impact customer experience and business growth. Location : Louisville, KY or Dallas, TX (Work At Home with occasional office visits) Key Responsibilities Engineering Leadership & Strategy Lead full stack engineering strategy and execution across UI, APIs, and data platforms Define architectural direction and ensure high standards for code quality, scalability, and maintainability Select frameworks, languages, and platforms across front-end, back-end, APIs, and data layers Approve architectural patterns (monolith vs. microservices, cloud strategy, and integrations) Identify opportunities to refactor, modernize, or retire legacy systems Delivery Execution & Prioritization Drive consistent delivery across multiple engineering teams through: Sprint planning and execution Dependency management Risk mitigation Removal of technical and organizational blockers Prioritize feature development, platf

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📍 Tampa Florida United States, United States
✓ Quality checkedCompany trend +800%

The Engineering Lead Analyst – SonarQube & Code Quality Engineering is a senior-level engineering role responsible for leading static code analysis, automated code quality governance, security vulnerability remediation, and AI-augmented developer enablement across enterprise software delivery pipelines. In this role, you will champion software reliability, maintainability, clean-coding standards, and automated quality gates. You will partner with development teams, system architects, and platform engineering to integrate and manage enterprise-scale code quality platforms (such as SonarQube) both on-premises and in cloud/SaaS environments. Additionally, you will drive modern engineering practices by embedding Behavior-Driven Development (BDD) within your own software delivery and leveraging Agentic AI workers and Model Context Protocol (MCP) architectures to optimize developer experience, streamline code governance, and boost engineering velocity. Key Responsibilities 1. Code Quality & Static Analysis Platform Ownership Lead the architecture, deployment, administration, and continuous enhancement of enterprise Static Application Security Testing (SAST) and Code Quality platforms (e.g., SonarQube , DeepSource, Codacy, Semgrep). Configure, calibrate, and enforce automated Quality Gates, code rulesets, technical debt calculation models, and code-coverage baselines across multi-language enterprise repositories. Oversee version upgrades, patching, high availability, and operational maintenance for on-premises and SaaS/cloud-hosted code quality infrastructure. 2. CI/CD & Pipeline Integration <li style=

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