Jobs in United States

Lead Infrastructure Software Engineer in United States

2,624 active opportunities · Updated October 2026

Explore current lead infrastructure software engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 562 related jobs

Hiring trend

-78.6%

Job postings compared with the previous 30 days

Remote options

15.8%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 31 salary observations

C
📍 Irving Texas United States, United States
✓ Quality checkedCompany trend +800%

We are seeking an experienced Paid Media Audience Strategy & Data Architecture Lead to drive audience planning, activation strategy, and data-enabled marketing initiatives across the paid media ecosystem. This role combines strategic audience development with data architecture expertise, helping the organization identify, prioritize, and activate audiences that drive business outcomes. The successful candidate will lead the development of audience frameworks that answer key strategic questions: Who should we target? When should we engage them? Where should we reach them? Why are they valuable? Working closely with Marketing, Analytics, Data Science, Media, and Technology teams, this individual will translate customer insights and business goals into scalable audience strategies while ensuring data is appropriately integrated, governed, and activated across MarTech and AdTech platforms. The ideal candidate is a strategic audience expert who understands how to combine customer insights, first-party data, and marketing technology to develop effective targeting strategies. They can define who to target, when to engage them, where to activate them, and why they matter, while partnering across teams to operationalize those strategies and drive measurable business outcomes. Responsibilities: Audience Strategy & Planning: Develop audience strategies that support customer acquisition, cross-sell, engagement, and retention objectives, define target audience frameworks using customer behavior, lifecycle stage, demographics, transactional data, and behavioral signals, determine the optimal timing, channel, and messaging approach for audience engagement, partner with business stakeholders to identify high-value audience opportunities aligned with strategic priorities and establish audience selection methodologies, segmentation standards, and measurement frameworks. Customer Insights & Audi

SQLArtificial IntelligenceAICRM
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📍 New Jersey, Parsippany, United States
✓ Quality checkedCompany trend -1.6%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description We are seeking a Clinical Data Scientist -RWE Data Analysis Oversight Lead: Inflammation. This position is responsible for the oversight of timeliness and quality of analysis results supporting the CDS-RWE book of work for the Inflammation therapeutic area (TA). This role reports to the CDS-RWE TA Head and supports the scientific leads in implementing strategies to generate analysis results that deliver on portfolio priorities. Serving as the primary point of contact for study and analysis vendors and service vendors, this role is responsible for planning, execution, and quality acceptance of analysis deliverables. The position requires demonstrated experience in managing complex analytical w

Recruitment
R
📍 Foster City, California, United States· Full-time
✓ Quality checkedCompany trend -87.5%

Replit is the agentic software creation platform that enables anyone to build applications using natural language. With millions of users worldwide, Replit is democratizing software development by removing traditional barriers to application creation. About the role: Replit’s ecosystem is powered by an expanding array of external services and essential AI model partners. As our lead for Security Vendor Risk & Contract Reviews, you will architect and execute a risk management program focused on substantive evaluation rather than just processing checklists. You’ll analyze SOC 2 documentation, security assessments, and system architectures to determine actual risk profiles, collaborating with our Legal team to secure necessary contractual protections. This role reports to the Head of Security GRC and involves high-impact partnerships across Legal, Engineering, and Product teams. What You'll Do Run substantive third-party risk management (TPRM), independently evaluating real risk, not just processing questionnaire responses Review SOC 2 reports, pen test findings, and architecture documentation to form an independent view of vendor risk, extending the same rigor to AI/model providers Partner with Legal on vendor and AI contract terms, including DPAs, subprocessor agreements, and AI-specific provisions Review contracts for non-standard security language when flagged by Legal or deal desk, and recommend redlines Maintain the vendor and AI/model risk register, feeding findings into the company's master risk register Enable sales through maturing the customer trust program Build the capability for continuous monitoring of vendor ecosystem Required Skills & Experience 8+ years in third-party/vendor risk management, security risk, or a related GRC role Demonstrated ability to independently assess vendor risk rather than relying on questionnaire responses alone, fluent in reading SOC 2 reports, ISO certificates, pen test summaries, and architecture documentation Experi

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $170K/yr

Quick readStrong listing-quality and freshness signals

Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog's Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company's interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Support Datadog's AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem through meetups, conferences, and events. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog's AI roadmap. Support negotiation processes, including term sheets and partnership structures, and collaborate on integration planning with cross-functional partners after deals close. Help attract early-stage AI companies into Datadog's startup program. Wh

RestAIGoRust
A
📍 United States· Full-time
✓ Quality checkedCompany trend -99%

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Our team is growing, and we want you to be part of it! You’ll join a collaborative group within Airbnb’s Chief Business Officer organization focused on expanding our Monthly Stays offering. We recruit and develop Airbnb’s global supply of high-quality stays and execute our in-market strategy to drive international growth. By building strong relationships with hosts and helping them optimize their listings and pricing, our team creates lasting host success and facilitates millions of connections between guests and hosts around the world. The Difference You Will Make: As a Senior Programs and Business Operations Lead, you will work with the Homes Leadership to develop and execute strategies to grow the success of Airbnb globally. You will also align with Homes Leadership, regional teams and cross functional teams to analyze data and deliver strategic recommendations to drive the Homes business globally. Your attention to detail, organization, ability to multitask, work on multiple priorities and work under pressure will all ensure you succeed. You should be great at understanding the needs of the airbnb community and defining levers to help them succeed in the platform. You will develop strong relationships and deliver valuable guidance to help them grow within

N
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -88.6%

$250K – $280K/yr

Quick readStrong listing-quality and freshness signals

Who We Are Notion is the collaborative AI workspace where teams and agents think together . We're building one place where your knowledge, projects, meetings, and AI tools live side by side, so work is faster, clearer, and less fragmented. Millions of individuals, small teams, and large companies run their work on Notion. Notinos (our employees) are customer zero in bringing this future of work to life. We care about craft, building things that last, and the belief that great work is still fundamentally human. Our goal isn’t to ship the next feature. Each and every team of Notinos is working to set the standard for how humans work together in the AI era. From building a business’s system of record to making and managing AI agents to automating away the busy work, we care deeply about giving our customers more time for their life’s work. About the Role: Notion’s global Outcomes organization is focused on helping customers achieve business objectives with Notion. As the Growth Strategy & Programs Lead, you will help design and scale the programs, operating rhythms, and cross-functional initiatives that make install-base growth more explosive and repeatable globally. This is a high-impact strategy and programs role. You will create the clarity, structure, and execution systems that help the business grow existing customers more deliberately. You will bring analytical rigor to how we understand growth, translate insights into scalable programs, and help teams execute with consistency while still allowing for local market nuance. The ideal candidate is equally comfortable building a model, writing a crisp recommendation, aligning executive stakeholders, and turning a strategy into a practical field motion. This role will be based in San Francisco. We work from our offices on Mondays, Tuesdays and Thursdays (our Anchor Days) because we do our best thinking and building together in person. We’re looking for someone who’s excited to work alongside the team during those

PE
📍 Vienna, Virginia, United States· Full-time· Hybrid
✓ Quality checked

Shape the Future with Dun & Bradstreet At Dun & Bradstreet, we believe data has the power to create a better tomorrow. As a global leader in business decisioning data and analytics, we help companies worldwide grow, manage risk, and innovate. Since 1841, businesses have trusted us to turn uncertainty into opportunity. We’re a diverse, global team that values creativity, collaboration, and bold ideas. Are you ready to make an impact and help shape what’s next? Join us! Explore opportunities at dnb.com/careers. The Senior Principal Data Scientist - AI Lead will be the point of contact for Public Sector / Government stakeholders and will be responsible for end-to-end AI solution delivery. This role will partner with U.S. government agencies on programs that depend on trusted entity data, validation, and risk insight.

MT
📍 Boise, ID - Main Site, United States· Hybrid
✓ High-confidence listingCompany trend +1150%
Quick readStrong listing-quality and freshness signals

Our vision is to transform how the world uses information to enrich life for all . Micron Technology is a world leader in innovating memory and storage solutions that accelerate the transformation of information into intelligence, inspiring the world to learn, communicate and advance faster than ever. Department Intro: We are advancing the future of semiconductor packaging through innovative 2.5D, 3D, and heterogeneous integration technologies. Our team develops the processes that enable next-generation AI and high-performance computing products, working across materials, device, design, manufacturing, and test engineering to solve complex technical challenges. If you're excited by emerging packaging architectures and breakthrough integration approaches, you'll find meaningful opportunities to make an impact here. Position Overview: As a Process Integration Lead for Advanced Packaging, you will lead a team focused on developing and integrating advanced packaging technologies from concept through full-scale manufacturing. This role plays a critical part in enabling high-performance multi-die solutions by driving technology development, process integration, technology transfer, and collaborative execution. You will help shape the roadmap for next-generation packaging platforms while mentoring a highly skilled technical team. Responsibilities: Manage and grow a team responsible for seamless process integration across 2.5D and 3D packaging platforms, including advanced interconnect architectures, die-stacking solutions, and HBM implementation. Spearhead the development, optimization, and qualification of emerging packaging technologies through experimental design (DOE), process analysis, performance validation, and establishment of design rules. Improve

AIRecruitment
G
📍 3409 Gllc Town Sq Alpharetta Ga, Client Office, United States
✓ Quality checkedCompany trend -66.7%

Sr. Tech Lead - Application Development JAVA N Ready to turn bold ideas into real-world impact? At Genpact, we don’t just adapt to change, we lead it. AI and digital innovation are transforming the way businesses work, and we’re at the forefront of it. Genpact’s AI Gigafactory , our industry-first accelerator, exemplifies how we scale advanced technology solutions to help global enterprises work smarter, grow faster, and transform at scale. Whether tackling complex challenges through large-scale models or agentic AI , our breakthrough solutions tackle companies’ most complex challenges. If you thrive in a fast-moving, innovation-driven environment, love building and deploying cutting-edge AI solutions, and want to push the boundaries of what’s possible, this is your moment. Genpact (NYSE: G) is an agentic and advanced technology solutions company. We leverage process intelligence and artificial intelligence to deliver measurable outcomes. With a strong partner ecosystem and decades of client trust, we provide innovative solutions that transform how businesses run. Powered by a team with an active learning mindset and client centricity at its core, we deliver lasting value for the world’s leading enterprises. Get to know us at genpact.com and on LinkedIn , YouTube , X , and Facebook . Job Description • Lead the design and implementation of Java-based applications; • Provide

JavaArtificial IntelligenceAI
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Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 Connecticut, Groton, United States
✓ High-confidence listingCompany trend +68.8%

$88.5K – $147.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Asset Lifecycle Management (ALM) Lead is responsible for the systematic tracking, installation, and removal of laboratory equipment throughout the entire lifecycle, from acquisition through deployment, maintenance, and final disposal. Operating within an R&D environment, this role facilitates asset preplanning, site assessments, and ensures all asset-related activities are documented, tracked, and compliant with regulatory standards. By optimizing equipment usage, managing inventory, coordinating maintenance, and driving process improvements, the ALM supports efficient and safe laboratory operations while controlling costs and enabling the lab for evolving technological requirements. This is to include but not be limited to supporting the regular updates and reconciliation of the Fixed Asset Registry (FAR) and physical inventory field activities. With input from both the customer equipment owner and the original equipment manufacturer (OEM), this role will develop the correct service program for assets within EAMS (Enterprise Asset Management System) or Pfizer’s Computerized Maintenance Management System (CMMS). Additionally, this position will be responsible for the documentation of asset maintenance activities within EAMS and support site EAMS administration requiring the review of training requirements and On the Job Training (OJT) for new resources requiring system access. The Asset Lifecycle Manager will also represent the site on various Global Workplace Experience (GWE) Communities of Practice or multi-site or global teams ensuring best practices and standards are being leveraged across the broader R&D portfolio. This position will foster and maintain working relationships with GWE, Preclinical & Translational Sciences (P&TS) Research and business operations team colleague and contractors to analyze needs, provide recommendations, and execute plans and options that ali

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