Jobs in United States

Lead Senior Full Stack Software Engineer 2c Api Experience in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior full stack software engineer 2c api experience jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 543 related jobs

Hiring trend

-76.6%

Job postings compared with the previous 30 days

Remote options

15.1%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 29 salary observations

N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

As one of the technology industry's most desirable employers, NVIDIA has been redefining accelerated computing, computer graphics and leading the Artificial Intelligence revolution. NVIDIA's innovation is fueled by its great technology—and amazing people. We are seeking a Senior Silicon and System Product Lead to influence, innovate and take our next generation products to the market. As part of the Silicon Solutions Team, we architect and deliver groundbreaking system solutions that integrate all aspects of the system from silicon design, software design to operations and final deployment in multiple market segments that NVIDIA serves. This position offers an unique opportunity to collaborate with multiple organizations in the company and grow your career in a high impact role. We need a passionate, hard-working and creative individual to lead the products all the way from market analysis to delivering the features on the final product. What you'll be doing: Drive product performance and power targets, trade-off features/configurations and provide innovative solutions to complex silicon and system level problems. Evaluate new market segments and use cases; translate market requirements to engineering problem statements and metrics. Innovate Performance, power, yield and quality optimizations and features for the world’s fastest power-shipping products in the GPU and SoC market segments spanning gaming, automotive, datacenter and DL/AI. Develop methodologies and requirements for multi-functional teams to drive silicon and system product features to production. Incorporate productization feedback to improve the next generation. Lead the team for feature requirements and schedule from architecture to silicon phase of projects. Work alongside system architects, designers, marketing teams, chip and board designers, software/firmware engineers, HW/S

Artificial IntelligenceAI
P
📍 Connecticut, United States
✓ High-confidence listingCompany trend +671.4%

$88.5K – $147.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Asset Lifecycle Management (ALM) Lead is responsible for the systematic tracking, installation, and removal of laboratory equipment throughout the entire lifecycle, from acquisition through deployment, maintenance, and final disposal. Operating within an R&D environment, this role facilitates asset preplanning, site assessments, and ensures all asset-related activities are documented, tracked, and compliant with regulatory standards. By optimizing equipment usage, managing inventory, coordinating maintenance, and driving process improvements, the ALM supports efficient and safe laboratory operations while controlling costs and enabling the lab for evolving technological requirements. This is to include but not be limited to supporting the regular updates and reconciliation of the Fixed Asset Registry (FAR) and physical inventory field activities. With input from both the customer equipment owner and the original equipment manufacturer (OEM), this role will develop the correct service program for assets within EAMS (Enterprise Asset Management System) or Pfizer’s Computerized Maintenance Management System (CMMS). Additionally, this position will be responsible for the documentation of asset maintenance activities within EAMS and support site EAMS administration requiring the review of training requirements and On the Job Training (OJT) for new resources requiring system access. The Asset Lifecycle Manager will also represent the site on various Global Workplace Experience (GWE) Communities of Practice or multi-site or global teams ensuring best practices and standards are being leveraged across the broader R&D portfolio. This position will foster and maintain working relationships with GWE, Preclinical & Translational Sciences (P&TS) Research and business operations team colleague and contractors to analyze needs, provide recommendations, and execute plans and options that ali

AIExcelProject ManagementAccounting
G
📍 California, United States
✓ Quality checkedCompany trend +190.5%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

Recruitment
C
📍 Farmington, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary At Aetna®, part of CVS Health, we proudly serve more than 26 million medical members through our broad range of health plan offerings. We're committed to delivering a simpler, more meaningful, and personal health care experience to each of them. As a Senior Manager Medicare Product, Vendor Management Contract Lead you will play a critical role contracting, negotiations, oversight of vendors and assisting in achieving CVS goals, work strategically together, and remain as adaptable as possible in an ever-changing environment. This role's scope of responsibility includes overseeing the following in relation to Medicare Product vendor management: Finance, Contracts, Invoicing, Negotiations, Provisioning, Aetna Medicare Supplemental & Duals benefits, Vendor relationship management, Compliance oversight, Auditing, and projects as assigned. The Senior Manager, Vendor Management Contract Lead is a high impact role. You will lead advance contract and negotiation skills, work with other partner to identify root cause, address, and resolve vendor issues, manage vendors to the contract SLAs, performance guarantees and provide insight into complex vendor problems. Responsibilities include: Work assignments involving moderately complex to complex issues where the analysis of situations or data requires an in-dep

FinanceAuditing
N
📍 Santa Clara, United States
✓ High-confidence listingCompany trend -8%
Quick readStrong listing-quality and freshness signals

We at NVIDIA seek an Senior Developer Relations, Automated Synthetic Chemistry Science Lead who can coordinate science streams. This role exists at the crossroads of experimental science, optimization, analytical characterization, AI modeling, laboratory automation, and data infrastructure. It demands a practitioner with a background in research who can lead interdisciplinary science teams and accelerate experimentation without compromising scientific quality. What you'll be doing: Coordinate the operating plan across research priorities, technical execution, and program achievements. Convert research objectives into experimental priorities, parameter-space development, campaign planning, and success criteria. Lead research initiatives encompassing synthetic chemistry, catalysis, process chemistry, machine learning, automated systems, and data processing. Build standardized experimental traces capturing successful and unsuccessful outcomes, metadata, quality-control signals, analytical summaries. Guide AI systems for feasibility assessment, outcome prediction, optimization, scope exploration, and campaign orchestration. Integrate automated experimentation, analytical data streams, data curation, model retraining, and campaign decisions into a closed-loop operating model. Establish science-stream governance: build reviews, decision logs, risk and dependency tracking, quality thresholds, and paths for addressing blocking issues. Prepare recurring workstream readouts for program leadership, including scientific progress, critical decisions, cross-team dependencies, resource needs, and unresolved risks. What we need to see: PhD (or equivalent experience) with 10+ years of hands-on experience in experimental science, chemical engineering, material science, robotics, a

Machine LearningAI
G
📍 California, United States
✓ High-confidence listingCompany trend +190.5%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%
Quick readStrong listing-quality and freshness signals

Datadog's integrations are the connective tissue between our platform and the technologies our customers run in the real world. As a Sr. PM on the Agent Integrations team, you will own the vision, prioritization, and execution for 100+ integrations that run directly inside the Datadog Agent from foundational infrastructure (MySQL, Kafka, Kubernetes) to the rapidly growing landscape of self-hosted AI and on-premise enterprise technologies. This is a high-impact, breadth-first role at the intersection of infrastructure observability and the frontier of AI-native workloads. At Datadog, we place value in our office culture; the relationships it builds, the creativity it brings, and the collaboration of being together. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Own the Agent Integrations roadmap. Determine which new integrations to build and which existing ones to improve, balancing customer demand, business impact, and engineering capacity across a catalog of 100+ technologies. Drive the expanding AI integration surface. Lead product strategy for self-hosted AI workloads, including LLM inference frameworks (e.g., Hugging Face TGI, BentoML), AI agents, MCP servers, and model orchestration tools, so Datadog customers can monitor every layer of their AI stack. Expand on-prem and hybrid coverage. Prioritize and execute new integrations for on-prem technologies including storage systems, HPC schedulers, network devices, and legacy enterprise platforms where customers run critical workloads. Build observability for ERP systems. Define and drive Datadog's strategy for monitoring enterprise ERP platforms (SAP, Oracle EBS/Fusion, Microsoft Dynamics) covering performance, job execution health, and integration layer telemetry so enterprise customers can observe their ERP stack alongside the rest of their infrastructure. Analyze adoption and customer feedback at scale. Use data from multiple sources to

SQLPostgreSQLMySQLMongoDB
C
📍 Tampa Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Applications Development Technology Lead Analyst is a senior level position responsible for establishing and implementing new or revised application systems and programs in coordination with the Technology team. The overall objective of this role is to lead applications systems analysis and programming activities. Responsibilities: Partner with multiple management teams to ensure appropriate integration of functions to meet goals as well as identify and define necessary system enhancements to deploy new products and process improvements Resolve variety of high impact problems/projects through in-depth evaluation of complex business processes, system processes, and industry standards Provide expertise in area and advanced knowledge of applications programming and ensure application design adheres to the overall architecture blueprint Utilize advanced knowledge of system flow and develop standards for coding, testing, debugging, and implementation Develop comprehensive knowledge of how areas of business, such as architecture and infrastructure, integrate to accomplish business goals Provide in-depth analysis with interpretive thinking to define issues and develop innovative solutions Serve as advisor or coach to mid-level developers and analysts, allocating work as necessary Appropriately assess risk when business decisions are made, demonstrating particular consideration for the firm's reputation and safeguarding Citigroup, its clients and assets, by driving compliance with applicable laws, rules and regulations, adhering to Policy, applying sound ethical judgment regarding personal behavior, conduct and business practices, and escalating, managing and reporting control issues with transparency. Recommended Qualifications: 6+ years of relevant experience in Apps Development or systems analysis role Extensive exp

SQLGitArtificial IntelligenceAI
C
📍 Jacksonville Florida United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

The Ops Sup Lead Analyst is a senior-level operations professional responsible for managing transaction exception processing, including payment network claims, adjustments, disputes, settlement exceptions, and reconciliation activities for internal Citi business partners. The role is accountable for ensuring the accurate and timely resolution of operational exceptions, maintaining a strong control environment, and overseeing third-party vendors that support these functions. This individual serves as the primary liaison between Operations, Business, Technology, Risk & Control partners, payment networks, and external vendors to ensure operational issues are resolved effectively, controls are maintained, and processes continue to evolve to support business growth and regulatory expectations. The successful candidate will act as a subject matter expert in payment network operations, transaction routing, settlements, reconciliations, and exception management. Responsibilities Lead the end-to-end management and resolution of transaction exceptions, including payment network claims, adjustments, disputes, settlement discrepancies, and other operational exceptions. Oversee settlement and reconciliation processes to ensure the timely identification, investigation, and resolution of breaks, variances, and outstanding items. Monitor operational performance and service level adherence, ensuring all activities are completed accurately, timely, and in compliance with applicable policies and procedures. Serve as the primary operational liaison with internal Citi business partners, Technology, Risk & Control, Compliance, Finance, payment networks, and third-party vendors. Manage vendor relationships supporting claims, adjustments, settlement, and reconciliation functions, including performance monitoring, issue escalation, service delivery oversight, and process improvements. Act as the b

Artificial IntelligenceAIFinance
LA
📍 New York, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

ROLE SUMMARY We are looking for a Senior Data Scientist to lead complex data science engagements that combine traditional statistical modelling with Generative AI. You will work hands-on with very large datasets across disparate systems and formats, translate ambiguous business problems into rigorous analytical solutions, and present those solutions clearly to C-level stakeholders. This is a delivery-first role with a fast track into technical leadership: alongside your own project work, you will help guide junior data scientists and shape how Lynx builds and ships data science solutions. KEY RESPONSIBILITIES Solution Design & Delivery Design and deliver end-to-end solutions for defined data science problems, combining classical modelling, data transformation, and Generative AI / LLM techniques. Work hands-on with very large datasets across disparate stores and formats, from ingestion and transformation through to modelling and validation. Apply statistical and machine learning methods to business problems such as customer retention, campaign management, and commercial performance optimisation. Client Communication & Leadership Present results and prepare client-ready materials for project stakeholders, including C-level audiences, translating technical work into clear business narratives. Lead smaller data science workstreams, with support from internal leadership and the PMO, including day-to-day guidance for junior team members. Partner with delivery and account teams to scope problems, set realistic timelines, and manage stakeholder expectations. Knowledge Building Create reusable documentation, presentations, and code libraries during projects so future engagements can build on prior work. Participate in internal education, research, and knowledge-sharing initiatives that raise the technical bar across the practice. SKILLS, QUALIFICATIONS AND EXPERIENCE 8+ years of overall experience in data science, with a track record of leading analytic

PythonSQLAWSAzure
C
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -94.7%
Quick readStrong listing-quality and freshness signals

Coder is looking for a Senior Staff Product Manager to lead our product management function and raise the bar for how we build. You will develop PMs, strengthen product execution, and help turn strategy into measurable outcomes for customers and teams. You will manage a small team of product managers while partnering closely with Engineering, Design, GTM, and executive leadership. You will coach people, improve systems, and keep product decisions grounded in real customer evidence. What you’ll do here Coach and develop product managers at every stage, helping strong executors grow into strategic leaders. Set a high bar for product discovery, planning, execution, and measurement. Partner with Engineering, Design, Customer Success, Sales, and Marketing to align priorities and deliver outcomes. Create clarity around product priorities, tradeoffs, and investment decisions. Build a culture of ownership, accountability, authority, and autonomy across the product organization. Lead customer discovery and ensure product decisions are grounded in objective evidence, not assumptions. Improve how the product organization operates, including planning, roadmap development, product reviews, and decision-making frameworks. Serve as a senior product leader and trusted partner to executive leadership. What we’re looking for Significant product management experience, including experience leading or managing product managers. A strong track record of coaching and developing PM talent. Excellent customer discovery and validation skills, including interviews that uncover objective insights and real customer needs. Sound judgment and pragmatism. You know when to optimize for outcomes, when to improve process, and how to balance strategy with execution. A strong sense of ownership and accountability, with the ability to build those qualities across a team. Clear communication skills and the ability to influence across functions, levels, and priorities. Experience operating in fast-moving

AWSAIGoRust
D
📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -83.5%
Quick readStrong listing-quality and freshness signals

Datadog is looking for a Senior Product Manager to help lead the evolution of our fleet and lifecycle management capability, the product surface that gives customers visibility into, and control over, the observability software running across their infrastructure. This capability manages the deployment lifecycle for core observability agents and OpenTelemetry collectors running on customer hosts and containers. The Senior PM will expand the scope of fleet capability to additional Datadog software components, making it the single place customers go to see everything running in their environment, at any version, in any deployment model, and to manage it remotely and safely at scale, for both human operators and, increasingly, AI agents acting on their behalf. This is a high-visibility, cross-functional role. You'll partner with multiple engineering teams and be responsible for defining and delivering a coherent, unified fleet experience across UI, API, and MCP for customers. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do Own and evolve the product vision and roadmap for a unified fleet and lifecycle management capability spanning multiple product lines and deployment models. Define what "managed" means for each new software component as it's brought into fleet, balancing consistency of experience with the realities of each component's operational model. Drive a phased expansion plan, sequencing new components into fleet based on customer value, technical complexity, and dependency readiness. Partner closely with engineering leads across several teams to align on shared architecture principles to support disparate software components. Represent the voice of the customer for a capability that must work equally well for human operators using a UI and for AI

KubernetesAIGoRust
M
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

From $92K/yr

Quick readStrong listing-quality and freshness signals

We are hiring a Senior Technical Product Marketing Manager to lead positioning and messaging and to grow adoption of MongoDB Search and Vector Search as foundational components of our platform – the retrieval layer powering the next generation of grounded AI applications and agents. This is a high-impact role for a marketer who thinks like a builder. As developers architect increasingly sophisticated systems – RAG pipelines, agentic workflows, multi-modal search experiences – retrieval has moved from an implementation detail to a core design decision. You’ll join a high-performing, globally distributed team and partner closely with Marketing, Builder Relations, Product Management, Engineering, Partners, and Sales to develop, measure, and achieve cross-functional goals. The role requires technical depth in information retrieval — lexical and vector search, hybrid approaches, embeddings, re-ranking, agentic retrieval loops, and the tradeoffs that matter in production systems — paired with the product marketing instincts to turn that depth into crisp, differentiated messaging for distinct user and buyer personas. Hands-on experience building or shipping AI-enabled products is a strong advantage. Individuals with prior experience in technical sales, developer relations, or technical marketing are encouraged to apply. This person is a voracious consumer of AI research and pays close attention to shifting patterns in application architectures and development, including agentic systems. This individual is confident in communicating with technical practitioners and non-technical decision makers in one-to-few and one-to-many engagements for internal and external audiences. We are looking to speak to candidates who are based in the US for our hybrid working model. What You’ll Do Drive Strategy & Execution: Act as a strategic partner for high-impact initiatives that align with MongoDB’s long-term business goals in collaboration with Marketing, Developer Relations, Product

MongoDBAWSAzureAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Role We are looking for a senior partner success and learning professional to activate cloud partners to co-sell and deploy customer solutions at scale. This role leads the enablement strategy and execution that equip partner teams to turn joint priorities into measurable customer and business outcomes. As a trusted advisor to strategic partners, you will turn shared business priorities into practical enablement programs that help partner sales, technical, customer success, and leadership teams identify joint opportunities, co-sell effectively, and deploy customer solutions successfully. You will own the partner enablement relationship for an assigned portfolio and work across internal teams to ensure programs are coordinated, scalable, and connected to measurable partner, customer, and business outcomes. This is not a traditional training delivery role or a quota-carrying partner account manager position. It is a consultative, partner-facing role for someone who can shape strategy, build relationships, translate complex AI capabilities into effective learning experiences, lead persuasive enablement sessions, and guide strategic partners toward sustained success. In this role, you will: Own strategic partner enablement and success Serve as the primary enablement and success lead for a portfolio of strategic cloud platforms. Develop a deep understanding of each partner’s business, priorities, audiences, existing learning infrastructure, and strategic relationship with our company. Build partner-specific enablement strategies aligned to shared goals, priorities, and the broader partnership strategy. Establish trusted relationships with partner leaders, alliance teams, enablement stakeholders, sales organizations, technical communities, and post-sales teams. Lead ongoing planning conversations, enablement reviews, stakeholder check-ins, and executive updates that keep partners and internal teams aligned. Identify gaps, risks, opportunities, and emerging partn

AWSRestMachine LearningAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -79.2%

About the Role We’re looking for a senior Strategic Finance Lead to help shape and execute OpenAI’s financial strategy across some of the company’s most important long-term investments and growth priorities. This high-impact role sits at the intersection of corporate finance, capital markets, treasury, and cross-functional execution. In this role, you will: Shape financial strategy for major long-term investments, capital structure decisions, and broader strategic decision-making. Build rigorous financial models and scalable frameworks to evaluate strategic initiatives, funding options, tradeoffs, and risk. Structure and help execute complex strategic initiatives in partnership with cross-functional teams. Translate ambiguous technical and business inputs into clear recommendations and decision-ready materials for executives, the board, and other senior stakeholders. Lead high-priority cross-functional workstreams from concept through execution, bringing strong judgment, ownership, and communication in fast-moving situations. Help build an AI-native finance organization by applying AI to improve workflows, decision-making, and execution across finance processes. You might thrive in this role if you have: 12+ years of experience across strategic finance, corporate finance, capital markets, investment banking, infrastructure finance, or related fields. A strong understanding of capital structure, financing strategy, debt markets, and large-scale investment evaluation. Experience operating in high-growth, high-complexity environments with the ability to navigate ambiguity and move quickly. Exceptional financial modeling, strategic thinking, and problem-solving capabilities. Strong executive presence with the ability to communicate clearly across investors, executives, and technical stakeholders. A high-agency operating style that combines strategic perspective with a willingness to build directly. Excitement around using AI as a core operating advantage, with a mindset

AWSRestAIGo

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