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Lead Senior Machine Learning Engineer Ii 2c Core Engineering in New York

300 active opportunities · Updated October 2026

Explore current lead senior machine learning engineer ii 2c core engineering jobs in New York. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

41/100

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Hiring trend

-76.2%

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Remote options

26.9%

Share of matching jobs listed as remote

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -87.2%

From $155K/yr

Quick readStrong listing-quality and freshness signals

Alerting is the beating heart of the Datadog platform. It is the critical bridge between raw data and decisive action, ensuring that when our customers’ systems falter, they are the first to know. Datadog is reimagining alerting; we’re evolving beyond simple triggers into providing a sophisticated, AI-powered posture that covers both known and unknown risks. As the Product Manager for Notification Orchestration, you will lead the evolution of how alerts reach the right people at the right time. You will define the strategy for our notification routing engine, ensuring that thousands of businesses can manage complex alerting logic without being overwhelmed by noise. You will empower customers to move beyond managing individual monitor outputs to a world where notifications are grouped, contextualized, and reliable at massive scale. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Develop a comprehensive understanding of customers and the core problems behind their alerting and notification monitoring challenges. Collaborate across product teams to identify and deliver the most critical alerts and health indicators for every product area. Define, build, and launch the next generation of user experiences for managing automated alerts and configurations. Design intuitive solutions that represent alert status and system health across the entire application, providing users with at-a-glance visibility. Join an engineering team to scope, spec, and design alerting features capable of supporting the most complex, high-scale organizations Continuously evolve the product with the latest technologies, including AI tools and agents. Partner with marketing and customer success teams to help users understand and adopt new alerting frameworks and health-monitoring

AIGoRustSpring
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -87.2%

From $192K/yr

Quick readStrong listing-quality and freshness signals

Datadog's Application Performance Monitoring (APM) provides deep visibility into the health, performance, and lifecycle of modern distributed applications, tracing requests from end-user devices (web and mobile) through to backend services. Our goal is to help customers detect root causes faster, optimize application performance, and improve resource efficiency at scale. As the Engineering Manager for APM Serverless, you will help define and deliver the end-to-end serverless APM experience, from auto-instrumentation through troubleshooting, and ensure that OpenTelemetry and Datadog-native customers alike have a frictionless and performant journey. You will also lead efforts to expand coverage of cloud-managed services across providers, ensuring customers can seamlessly trace and monitor critical services in all major and emerging cloud environments. We’re looking for an experienced engineering leader who thrives at the intersection of infrastructure and developer experience. You should care about well-designed APIs, observability-first thinking, and building systems that empower other developers. This is a high-leverage role that will influence how developers across the industry understand and instrument their serverless workloads. At Datadog, we place value in our office culture - the relationships that it builds, the creativity it brings to the table, and the collaboration of being together. We operate as a hybrid workplace to ensure our employees can create a work-life harmony that best fits them. What You’ll Do: Lead a polyglot team of 8-9 engineers and partner closely with Product and Engineering teams across Datadog to deliver industry-leading serverless capabilities that power consistent, scalable, and intuitive instrumentation across languages. Drive a domain that is technically rich: Lambda, Azure Functions, GCP, OTel billing, Rust, durable functions, distributed tracing across managed services. Engineers on this team work

AWSAzureGCPAI
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -87.2%

From $280K/yr

Quick readStrong listing-quality and freshness signals

The Detection Platform organization is responsible for helping customers identify, understand, and act on issues across their environments through alerting, event intelligence, and autonomous detection capabilities. As Director, Detection Platform, you will lead a group of engineering managers and teams responsible for foundational alerting infrastructure, event management, monitor creation experiences, and AI-powered detection systems. This role sits at the center of Datadog’s efforts to evolve how customers detect, investigate, and respond to operational issues at massive scale. You will partner closely with Product Management, Applied Science, Design, and Engineering leaders to shape the future of detection and observability experiences for Datadog customers while leading a growing organization of engineers. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do: Lead a multi-team engineering organization responsible for alerting, event management, monitor creation experiences, and autonomous detection capabilities. Define and execute the technical and organizational strategy for the Detection Platform while aligning stakeholders across Engineering, Product, Design, and Applied Science. Drive innovation in AI-powered detection, anomaly identification, and signal generation that helps customers proactively identify and resolve issues. Scale highly available platform systems that process hundreds of millions of evaluations while maintaining reliability, performance, and operational excellence. Develop and mentor engineering managers and technical leaders, fostering a culture of execution, collaboration, and technical rigor. Champion customer-centric product thinking by balancing platform investments with intuitive user experiences and measurable customer

Machine LearningAIGoRust
D
📍 New York, California, United States· Full-time
✓ High-confidence listingCompany trend -87.2%

From $330K/yr

Quick readStrong listing-quality and freshness signals

Datadog is expanding the Technical Solutions (TS) organization by seeking a customer-focused, deeply technical Distinguished Architect to join our Product Solutions Architecture (PSA) team. In this role, you will act as a technical multiplier for the world's leading AI labs and AI-native companies. You will bridge the gap between their bleeding-edge infrastructure aspirations and Datadog’s technology roadmap, ensuring our platform natively solves the unique observability challenges of training and deploying foundational models at scale. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Leadership : Demonstrate thought leadership in the AI/LLM space. Influence key decision makers and stakeholders by connecting technical capabilities to organizational and business impact. Advisory : Strategically partner with highly technical Founders, Heads of Infrastructure, and Research Lead peers. Guide them on best practices and emerging industry trends in the AI/LLM space. Lead high-level technical and architectural conversations around AI adoption. Presentations : Lead deep-dive architecture reviews and design engagements with customer teams and their leaders to share industry trends, best practices, and demonstrate how Datadog can support high-throughput hyper scale AI workloads. GTM : Identify emerging AI-native technology shifts and feed them directly back to Datadog Product Management. Co-create custom observability integrations and solutions alongside Product SAs to keep Datadog at the absolute forefront of the AI stack. Collaboration : Collaborate with Product Solutions Architecture (PSA), Sales, Sales Engineering and Marketing in providing high-quality technical resources to a broad audience of practitioners and economic buyers. Hiring : Assis

O
📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Product Policy team is responsible for the development, implementation, enforcement, and communication of the policies that govern use of OpenAI’s services, including ChatGPT, GPTs, the GPT Store, Codex, and the OpenAI API. About the Role We are looking for a Research and Advisory Partnerships Lead to build and manage the relationships, partnerships, and advisory structures that bring independent external expertise into our product and policy decisions. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will identify and engage researchers, civil society organizations, subject-matter experts, and other external stakeholders whose perspectives can strengthen how we develop and deploy AI. You will establish and manage advisory councils, develop research partnerships with the academic community, and work closely with internal teams to translate external insights into actionable guidance. This role sits at the intersection of product, policy, research, and governance. It is well suited to someone who is comfortable building relationships across disciplines and designing processes that ensure outside expertise meaningfully informs internal decision-making. This role can be based in San Francisco or New York City. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Develop, launch, and manage external advisory councils and other governance mechanisms that provide structured input on product and product policy. Build and maintain relationships with external experts, researchers, civil society organizations, and other stakeholders who can inform high-priority product and product policy decisions. Identify when external consultation can improve internal decision-making, and develop engagement strategies tailored to specific products, policy questions, and emer

AWSRestAIGo
O
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team OpenAI’s Forward Deployed Engineering team partners with healthcare organizations to deploy production AI systems across clinical, operational, and member-facing workflows. We work at the boundary of customer deployment and core platform development, using customer engagements to define repeatable architectures, evaluations, integrations, and operating standards for complex, regulated healthcare environments. About the role We are hiring a Forward Deployed Engineer (FDE) to own end-to-end deployments of our models within healthcare organizations, including payers, providers, health systems, and healthcare technology companies. You will lead technical discovery, architecture, implementation, evaluation, productionization, and handoff, translating complex customer workflows, data, infrastructure, and regulatory constraints into production AI systems. You will measure success through production adoption, measurable workflow impact, and evaluation loops that establish customer-specific benchmarks, acceptance criteria, and launch readiness. You’ll collaborate directly with customer technical and operational teams, alongside internal Business, Research, Product, Engineering, and Security partners, to deliver solutions and translate deployment learnings into product improvements. This role owns the technical solution; ownership of the commercial or executive relationship is not required. This role is based New York City. We use a hybrid work model of 3 days in the office per week. We offer relocation assistance. Travel up to 50% is required. In this role you will Own the technical solution end to end, from customer discovery and workflow scoping through architecture, hands-on implementation, evaluation, production deployment, adoption, and handoff. Partner credibly with customer engineers, operators, and domain experts to frame ambiguous problems, define scope, and translate payer, provider, or health-system workflows into technical requirements and measurab

AWSRestAIGo
P
📍 New York, United States
✓ High-confidence listingCompany trend +237.5%

$239.9K – $399.8K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Clinician Medical Monitor is accountable for providing medical and scientific expertise and oversight for Clinical Trials and serves as a single point of accountability for design, execution, monitoring, delivery and reporting of one or more clinical studies and to ensure patient safety. The clinician medical monitor may be required to design a development strategy for multiple protocols designed to obtain worldwide approval for a compound or group of compounds. In addition to study level activities, the clinician medical monitor may participate in standing committees, review compounds for potential in-licensing, including performance of due diligence reviews, and aid new business development on market opportunities and the target product profile. ROLE RESPONSIBILITIES Accountable for safety across the study Provide study team with medical advice for all medical issues during risk assessment and mitigation planning to enable quality, compliance and patient safety at the trial, site and patient level. Ensures development of and adherence to the Safety Surveillance Review Plan (SSRP). Consistent with the SSRP, performs and documents regular review of individual subject safety data, and performs review of cumulative safety data with the safety risk lead. As appropriate, the clinician medical monitor may delegate these responsibilities to the study clinician scientist identified in the SSRP. The specific components of safety data review are detailed in the appropriate SOPs and the “Safety Data Review Guide – for Clinicians.” Monitor study safety issues and provide input to serious adverse events (SAEs) reports. Provides appropriate medical context in terms of risk factors, medical history and other important medical factors required to put the SAE or AE into appropriate medical context required for benefit-risk assessm

AIRecruitment
C-
📍 New York, New York, United States
✓ High-confidence listing

$225K – $275K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. The Customer Success Director – Healthcare will own and execute CLEAR’s healthcare customer success strategy, driving long-term value, adoption, and expansion across our partner ecosystem. What you’ll do: Own and drive CLEAR’s customer success strategy across healthcare partners, ensuring strong adoption, retention, and expansion of CLEAR’s identity solution Build, develop, and lead a high-performing Customer Success function, setting clear goals, coaching team members, and driving a culture of accountability and excellence Establish and deepen executive-level relationships across healthcare organizations, positioning CLEAR as a trusted, strategic partner Partner cross-functionally with Business Development, Product, Technology, and Operations to shape and deliver scalable, high-impact customer experiences Lead end-to-end lifecycle management across complex healthcare implementations, from solution design and contracting through execution and ongoing optimization How you’ll measure success: Performance against renewals, contract expansion, and revenue growth across healthcare partners Product adoption, utilization, and successful rollout of new healthcare use cases Partner satisfaction, retention, and executive-level engagement Operational excellence across implementations, including on-time delivery and scalability What you're great at: 8+ years of experience in customer success, partnerships, consulting, or related roles, with significant experience in healthcare Proven track record of building and leading high-performin

P
📍 New York, United States
✓ High-confidence listingCompany trend +237.5%

$33 – $55/hr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary (GU) including both prostate and bladder, hematology-oncology and thoracic therapeutic areas. The primary purpose of this position will be to provide comprehensive day-to-day administrative support to the US Prostate Franchise Lead and to support the overall Franchise business. The Administrative Assistant will report to the US Prostate Vice President. In this role, the Administrative Assistant will be responsible for (but not limited to) heavy calendar management, coordination of meetings and events, development of agendas and meeting reports, slide development for select meetings, and requests and assembly of briefing materials, arranging travel and expense report preparation. As a working professional, he/she will be expected to handle tasks independently and in a proactive manner. <

AIExcelLogisticsRecruitment
B
📍 New York, New York, United States
✓ High-confidence listing

$270K – $335K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Legal at Brex The Legal team helps the company grow responsibly, advocating for Brex and for the thousands of growing businesses we serve. We provide strategic advice and guidance to all Brex teams, protect Brex, advise on risk, and represent the company externally, negotiating with partners and interacting with regulators. Reimagining the financial system in a highly regulated environment requires creativity and resourcefulness, and we welcome the challenge. Where you’ll work This role will be based in our New York City office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a minimum of three coordinated days in the office per week, Monday, Wednesday and Thursday. As a perk, we also have up to four weeks per year of fully remote work! What you'll do Reporting to the General Counsel, you will lead Brex's Regulatory

AIAccountingFinanceLogistics
C-
📍 New York, New York, United States
✓ High-confidence listing

$130K – $160K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. As a Sales Engineer II, you will be responsible for ensuring our customers successfully integrate with the CLEAR1 platform, with a focus on our Healthcare vertical. You will work across the Growth, Product, and Engineering teams to develop a deep understanding of the problems our customers are facing and influence how we’re building our platform for scale. We’re looking for a candidate with an excellent technical background who is looking to have a direct impact on customer and developer experiences. What you'll do: Lead presales customer engagements, including technical discovery, product demos, use case demos, RFPs, solution and integration scoping, and proof-of-concepts Drive customer integration for enterprise-level customers including building reference applications, prototypes, and architecture diagrams Develop code samples, integrations, and applications to demonstrate best practices and minimize customer development time, across a variety of languages and frameworks Support customers throughout the presales, proof of concept, and integration processes, assisting with common coding issues and patterns or troubleshooting Creating and maintaining public and internal documentation to help scale the team Act as the internal and external expert in the integration and usage of the CLEAR identity platform Collaborate across Sales, Product and Engineering to ensure that CLEAR strategically incorporates customer feedback and new product features into our roadmap Stay up-to-date with the latest trends and developments in the Healthc

C-
📍 New York, New York, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. CLEAR1 is CLEAR's B2B identity verification business, serving enterprise, healthcare, and workforce customers through direct sales and partners. We are growing fast and need a Revenue Operations Leader who can build the operating model to match. This is a strategy and accountability role. You will own how the go-to-market team plans, measures, forecasts, and runs its process across the full customer lifecycle, from first touch through renewal and expansion. You will define what our revenue numbers mean and where they come from, make them consistent from rep to Board, and hold the team to the process that produces them. You will be the CRO's partner on where to invest and what is working. You have done this before at a growth-stage B2B company, you think like a finance partner as much as an operator, and you direct systems work without needing to do it yourself. What you'll do: Own CLEAR1’s revenue operating model, partnering with the CRO and Finance on annual and quarterly planning across capacity, quotas, coverage, pipeline targets, and investment decisions Establish a single source of truth for revenue performance by defining core metrics, data sources, and reporting across ARR, net new ARR, GRR, NRR, pipeline coverage, win rate, sales cycle, and CAC payback; own executive and Board-level reporting Lead forecasting and revenue accountability end to end across new business, renewals, and expansion, establishing clear definitions, cadence, and ownership while continuously improving forecast accuracy Build and enforce scalable processes

AISalesforceFinanceCRM
C
📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -79.2%
Quick readStrong listing-quality and freshness signals

Who are we? Cohere is the leading security-first enterprise AI company. We build cutting-edge foundation AI models and end-to-end products that are designed to solve real-world business problems. We’re training and deploying frontier models for enterprises who are building AI systems. We believe that our work is instrumental to the widespread adoption of AI and we are looking for folks that want to be part of that. We obsess over what we build. Each one of us is responsible for contributing to increasing the capabilities of our models and the value they drive for our customers. Cohere is a team of researchers, engineers, designers, and more, who are all passionate about their craft. We are a global technology company headquartered in Toronto with key offices in London, New York City, San Francisco, Montreal, Paris, Berlin and Seoul. Join us! The Opportunity We're seeking an experienced Head of Non-Tech Talent to lead our comprehensive hiring strategy for all non-technical roles. This is a pivotal position as we build out our capabilities across General and Administrative (G&A) Go to Market (GTM) Finance, Legal, and other business-critical functions. You'll transform how we attract, hire, and develop top talent beyond while building and coaching a high performing global talent team. This is an opportunity to join an ambitious high performing, scale up company. Key Responsibilities Strategic Talent Leadership: Develop and execute the non-tech talent strategy aligned with Cohere's growth plan and business objectives while partnering with TA leads across the organization Team Development & Coaching: Recruit, mentor, and develop a high-performing team of non-tech recruiters, sourcers, and coordinators; create career paths and succession plans Process Innovation: Design and implement scalable hiring processes for non-technical roles while maintaining our high-quality standards Business Partnership: Serve as the primary talent advisor to our Talent Leads and partne

AIFinanceRecruitmentHR
B
📍 New York, New York, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Sales at Brex Sales is the growth engine at Brex. We bring in new customers, expand existing relationships, and drive the company’s bottom line. With unlimited territories and uncapped opportunity, your ambition sets the ceiling. We win together, celebrate often, and reward performance. If you want to sell a category-defining product with real ownership, this is your team. What you’ll do Lead discovery and shape the problem Conduct structured discovery to understand customer workflows, pain points, and decision criteria Identify key value drivers and align solutions to measurable business outcomes Challenge assumptions and provide a clear, differentiated point of view Own the solution narrative Design and deliver tailored product demonstrations that connect directly to customer needs Translate complex technical capabilities into clear, compelling business value Adapt messaging for technical, business, and executive audiences Drive dea

AIAccountingFinance
A
📍 New York, NY, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Who We Are Addepar is a global data and AI platform empowering investment professionals to turn complex financial information into actionable intelligence. Addepar unifies portfolio, market and client data in a total portfolio view and delivers AI-powered insights within investment and client workflows. More than 1,400 firms in nearly 60 countries use Addepar to manage and advise on nearly $9 trillion in assets. Its open platform integrates with nearly 650 software, data and consulting partners to power end-to-end investment operations across firms of all sizes and complexity. Addepar supports clients worldwide with offices in New York City, Salt Lake City, London, Edinburgh, Pune, Dubai, Geneva, Singapore and São Paulo. The Role The Advisor Experience team is a new engineering team within Addepar’s Core Product Engineering organization, focused on building the products and experiences that define how financial advisors and their clients interact on the Addepar platform. Initially this role will focus on our new Secure Message Center — a compliant messaging experience built into Addepar’s client portal — but the scope extends well beyond messaging. We’re building the connective tissue between advisors and the investors they serve, creating workflows that make every interaction more informed, more personal, and more seamless. As the Engineering Manager for this team, you’ll lead a small, growing group of engineers and shape both the technical direction and team culture from the early stages. You’ll partner closely with product management and design to translate an ambitious product vision into shipped software. Applicants must be legally authorized to work in the United States for any employer without requiring current or future visa sponsorship (for example, employment-based visas such as H-1B , F-1 /OPT, or similar), and must be authorized to begin work in the U.S. on their first day of employment. What You'll Do Lead, mentor, and grow a team of full-stack en

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