Jobs in United States

Lead Senior Python Engineer 2c Agentic Ai in United States

2,434 active opportunities · Updated October 2026

Explore current lead senior python engineer 2c agentic ai jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $243.3K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a member of the Infrastructure Foundation Hardware Engineering team, you will play a key role in enabling our mission to deliver a reliable, high-performing, and cost-efficient infrastructure that powers the world’s play. In this specialized role, you will be the technical lead for our GPU and AI accelerator ecosystem. You will be responsible for the full lifecycle of GPU hardware, from initial architectural evaluation and firmware qualification to large-scale fleet integration and performance tuning. You will ensure that Roblox’s massive-scale rendering and ML workloads run on the most optimized and stable hardware possible. You Will: Architect & Prototype: Prototype next-generation GPU-accelerated hardware platforms, ensuring seamless integration between high-density compute nodes, high-speed interconnects (NVLink/PCIe Gen5/6), and system firmware. GPU Optimization: Drive the integration, performance testing, and debugging of GPUs in our fleet, focusing specifically on hardware-level optimizations, driver tuning, and thermal/power management. Validation & Certification: Develop and execute rigorous evaluation and stress-testing strategies for GPU-heavy server platforms to ensur

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📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $196.8K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. As a Senior Software Engineer on our Ads Platform team, you will architect and build foundational ads systems that are capable of reliably serving Roblox’s massive scale. You will drive performance improvements to our ads serving and delivery infrastructure, while expanding our systems to support a variety of new and immersive ads experiences. Your scope will span across multiple teams and require close collaboration with engineers across ML, backend, and analytics to shape the future of ads infrastructure at Roblox. This role is a great fit for you if you are proficient in managing large scale systems and data-driven applications and have a zeal for developing inspiring, easily maintainable, and reusable code. Join our highly skilled and rapidly growing team and make a significant impact at Roblox. This position will report to our Senior Engineering Manager and require you to work onsite at our HQ in San Mateo, CA Tuesdays to Thursdays. You Will: Build and ship best-in-class Ads products used by hundreds of millions of users. Develop backend services that scale to billions of products and transactions. Be a tech lead and mentor junior engineers Self-organize and take ownership of projects

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R
📍 San Mateo, CA, United States· Full-time
✓ High-confidence listingCompany trend -100%

From $196.8K/yr

Quick readStrong listing-quality and freshness signals

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences– all created by our global community of developers and creators. At Roblox, we’re building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device. We’re on a mission to connect a billion people with optimism and civility, and looking for amazing talent to help us get there. A career at Roblox means you’ll be working to shape the future of human interaction, solving unique technical challenges at scale, and helping to create safer, more civil shared experiences for everyone. What You’ll Do: The Marketplace team, part of the Economy org, owns the platform and infrastructure that supports the Avatar customization and Avatar Marketplace within Roblox. As a Senior Engineer on our team, you will lead the work on building personalized and streamlined shopping experiences for over 100M users within Roblox. Beyond this scope, you will be involved with several additional areas also owned by subteams such as: Avatar Identity Scaling and Serving Avatars to tens of millions of users on the platform Building new Avatar customization features and continuously improving user experience Driving users and creators towards high-quality, high-fidelity Avatars that will shape Roblox’s look and feel going forward The systems above power the engine APIs that enable developers to monetize their games on Roblox, earning hundreds of millions of dollars per year, while processing billions of transactions. The ideal candidate is passionate about understanding customer needs, optimizing performance, and delivering exceptional user experiences. You Have: 3+ years of professional experience in software development Proficiency in one or more programming languages such as C#, Go,

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📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -92.9%

$220K – $288K/yr

Quick readStrong listing-quality and freshness signals

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. We are looking for a Senior Solution Engineer who thrives at the intersection of data, AI, and complex enterprise architecture. In this role you will work directly with the sales team and channel partners to understand the data challenges of our customers, strategize on how to navigate winning sales cycles, deliver compelling data-driven demonstrations, and support enterprise Proof of Concepts that showcase measurable business outcomes. As a Snowflake Solution Engineer you must share our passion for transforming how organizations use data — from raw ingestion to real-time analytics to AI-powered applications. You thrive in a dynamic environment, are equally comfortable whiteboarding a medallion architecture with a data engineering team and presenting data ROI to a C-suite, and you bring deep opinions about what good data platform design looks like. IN THIS ROLE YOU WILL GET TO: Present Snowflake's Data Cloud vision to data engineering leaders, analytics teams, data scientists, and executive stakeholders at prospects and customers Lead hands-on technical discovery to map a customer's existing data architecture — pipelines, warehouses, lakehouses, governance gaps — and design a Snowflake-native path forward Build and deliver tailored demos and proof of concepts across Snowfla

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RH
📍 Denver, Colorado, United States
✓ High-confidence listing

$118.7K – $160K/yr

Quick readStrong listing-quality and freshness signals

Healthcare is complex. We’re here to change that. RVO Health is a health technology company on a mission to make health easier to navigate, more accessible, and more affordable for everyone. Here, you'll help over 40 million people every month, with a team that genuinely cares about the work and each other. AT A GLANCE The Senior Software Engineer is a crucial role within our organization, requiring work in various capacities and adaptation to different work arrangements based on the needs set by the business. The successful candidate will be responsible for fulfilling their job duties in the following work situations: Where You'll Be Location: Denver, CO | Hybrid We believe great collaboration happens when we're together, solving problems, learning from each other, and connecting as a team. That's why we’re in our offices Tuesday through Thursday each week. You are welcome to work remotely Mondays and Fridays if you wish. Address: 1801 California St. Denver, CO 80202 What You’ll Do Lead the end-to-end design, development, and implementation of sophisticated software applications and systems aligned with business goals. Collaborate closely with stakeholders including product managers, designers, and other engineers to gather requirements and translate them into robust technical designs and solutions. Write high-quality, efficient, maintainable, and scalable code adhering to best practices and company standards. Debug, analyze, and resolve complex software defects and performance bottlenecks to ensure optimal system reliability and user experience. Conduct comprehensive testing and validation including unit, integration, and performance testing to guarantee software quality. Mentor and provide technical guidance to junior and mid-level engineers, fostering professional growth and knowledge sharing. Perform thorough code reviews to maintain high code quality, enforce coding standards, and promote best p

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📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -93.7%
Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: The Senior Platform Engineer II, AI Tooling on the Developer Experience Team (part of Foundation Engineering group) will lead the design and delivery of the internal AI platform that makes Drata's engineers more efficient - the tools, agents, and integrations that turn AI coding agents (and the rest of the AI dev stack) into a paved road for everyday engineering work. This is not a

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📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 The Mission The Foundry is ClickUp's internal AI innovation lab — embedded inside GTM Systems and accountable for turning AI capabilities into production-grade, internally deployed products that make every GTM function faster and smarter. We build the infrastructure that powers AI-first work across Sales, Marketing, Post-Sales, and Revenue Operations. As the Senior Software Engineer on this team you will own the technical delivery of our MCP server platform, agent orchestration layer, and internal tooling — shipping production systems used daily by hundreds of ClickUp employees, and scaling your own throughput by treating AI tools as first-class engineering collaborators. What You'll Own MCP Server Platform Design, build, and operate Model Context Protocol servers that expose CRM, ticketing, analytics, and communication data to AI agents across the GTM stack Implement Okta PKCE authentication flows and RBAC policy enforcement so agents access only the data they're authorized to touch Maintain deployment infrastructure on AWS (Bedrock, Lambda, ECS, API Gateway) and contribute to GCP workloads where applicable Own observability: structured logging, distributed tracing, latency SLOs, and on-call runbooks for every production server Agent Orchestration & AI-Native Products Build and maintain multi-step autonomous agents that execute end-to-end GTM workflows — lead qualification, deal room assembly, onboarding automation, support triage, and more Architect prompt engineering frameworks, tool-call schemas, and agent evaluation harnesses that make AI behavior predictable and auditable Integrate with LLM p

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TN
📍 New York, NY, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

The mission of The New York Times is to seek the truth and help people understand the world. That means independent journalism is at the heart of all we do as a company. It’s why we have a world-renowned newsroom that sends journalists to report on the ground from nearly 160 countries. It’s why we focus deeply on how our readers will experience our journalism, from print to audio to a world-class digital and app destination. And it’s why our business strategy centers on making journalism so good that it’s worth paying for. About the Role, Mission or Department Overview As a Senior Engineer, Marketing, you'll be embedded with the Marketing team, providing us with technical leadership, consulting, and systems thinking. You'll assemble the orchestration systems, integrations, and AI capabilities that help teams work faster, and in more data‑driven ways. You will lead end‑to‑end design, implementation, and management of the marketing campaign lifecycle system, integrations, internal tools, and learning/experimentation infrastructure. You will report to our Director, Advertising Systems. Responsibilities: You will write high-quality, secure, and well-tested code, contributing to standards and documentation for Marketing infrastructure, data models, and tools You will build the campaign lifecycle orchestration backbone You will build integrations and internal tools that connect project management, collaboration, creative, media, and email/lifecycle platforms You will work with Marketing partners as a technical advisor, translating needs into designs You will integrate AI agents and automations (including LLM-powered flows) into Marketing workflows according to company GenAI guidance You will design and operate data pipelines and models that ingest marketing and performance data into a data layer, supporting experimentation and analytics workflows You will deliver abstractions and APIs that ensure AI systems and our users to create campaign wrap-ups, insights, next-t

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📍 San Francisco, CA, United States
✓ Quality checkedCompany trend -100%

The Opportunity Typography is central to how ideas are communicated. If you're passionate about beautifully created design, have deep curiosity about what AI can do, and take personal responsibility for creating products that people love; then this may be the role for you. Adobe Fonts supports millions of creatives in choosing and using typefaces across fonts.adobe.com, Express, Photoshop, Illustrator, Acrobat, and more Creative Cloud platforms. Our Internal Services team provides the platform engineering and deployment backbone for all of these. We manage CI/CD, deployment approaches, the services and data layers our engineers depend on, our observability and security stance, and increasingly the agentic tools that transform how our entire organization delivers software. We're seeking a Senior Software Development Engineer to lead this exciting journey in our San Francisco location. What you'll do Own and evolve our deployment platform. Lead strategy for CI/CD, PR environments, and release safety across a mixed fleet that includes containerized services, serverless services, and static front ends. Build the foundation for AI-accelerated development. Help build our agent factory and grow our internal agentic toolkit and skill library. Ship inference applications at scale. Take greenfield services from spec to production and standardize our ML/inference footprint. Modernize our services for the AI era. Identify where an existing service is held back by its current build and lead the fix. Rethink our security posture for agentic threats. Lead how we secure autonomous agents and their tool use. Expose Adobe Fonts to the agentic ecosystem. Extend our Model Context Protocol (MCP) surface and conversational, intent-based font discovery. Work higher up the stack, too. Contribute directly to search, browse, discovery, and the customer-facing experie

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RH
📍 Denver, Colorado, United States· Full-time
✓ High-confidence listing

From $118.7K/yr

Quick readStrong listing-quality and freshness signals

Healthcare is complex. We're here to change that. RVO Health is a health technology company on a mission to make health easier to navigate, more accessible, and more affordable for everyone. Here, you'll help over 40 million people every month, with a team that genuinely cares about the work and each other. AT A GLANCE The Senior Software Engineer is a crucial role within our organization, requiring work in various capacities and adaptation to different work arrangements based on the needs set by the business. Where You'll Be Location: Denver, CO | Hybrid We believe great collaboration happens when we're together, solving problems, learning from each other, and connecting as a team. That's why we're in our offices Tuesday through Thursday each week. You are welcome to work remotely Mondays and Fridays if you wish. Office Address: 1801 California St. Denver, CO 80202 What You’ll Do Lead the end-to-end design, development, and implementation of sophisticated software applications and systems aligned with business goals. Collaborate closely with stakeholders including product managers, designers, and other engineers to gather requirements and translate them into robust technical designs and solutions. Write high-quality, efficient, maintainable, and scalable code adhering to best practices and company standards. Debug, analyze, and resolve complex software defects and performance bottlenecks to ensure optimal system reliability and user experience. Conduct comprehensive testing and validation including unit, integration, and performance testing to guarantee software quality. Mentor and provide technical guidance to junior and mid-level engineers, fostering professional growth and knowledge sharing. Perform thorough code reviews to maintain high code quality, enforce coding standards, and promote best practices across the team. Continuously improve software development processes, tools, and methodol

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C
📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 Role Overview: We are seeking a skilled and innovative Senior AI Engineer – AI Product to join our ClickUp Engineering team. In this role, you will drive the development of intelligent, user-facing features that leverage the latest advancements in AI and large language models (LLMs). You will work closely with product, design, and engineering teams to deliver seamless, impactful AI-powered experiences that delight our users and differentiate ClickUp in the productivity space. This is a product-focused engineering role requiring deep expertise in AI, LLMs, and building scalable, production-ready applications. Key Responsibilities: Lead the design, development, and deployment of AI-powered features and products that directly impact ClickUp users. Collaborate with product managers, designers, and engineers to identify opportunities for AI-driven innovation and translate user needs into technical solutions. Integrate and orchestrate multiple LLMs and AI models to deliver robust, context-aware, and personalized user experiences. Prototype, test, and iterate on new AI features, leveraging user feedback and data to drive continuous improvement. Ensure the reliability, scalability, and performance of AI-powered features in production environments. Stay at the forefront of AI research and product trends, incorporating the latest advancements into ClickUp’s product roadmap. Address AI privacy, security, and compliance challenges, ensuring responsible and ethical use of AI in user-facing applications. Mentor and guide other engineers in best practices for building AI-powered products. Qualifications: Proven exper

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📍 Bellevue, WA, United States· Full-time
✓ High-confidence listingCompany trend -91.7%
Quick readStrong listing-quality and freshness signals

For over 20 years, Smartsheet has empowered teams to manage work seamlessly and scale solutions smarter. Now, in our most ambitious chapter yet, we are uniting human teams with AI agents. By orchestrating the work agents do best, automating manual tasks and uncovering insights at scale, we create the space for people to focus on what truly matters: judgment, creativity, and big thinking. That is magic at work, and it’s what we show up for every day. Corporate Systems Engineering builds and operates the software platforms, integrations, and automations that power Smartsheet’s core business functions across Finance, Sales/GTM, and People & Culture. Our team owns mission-critical systems and workflows that enable how the company hires, sells, bills, pays, reports, and scales. We operate at the intersection of software engineering, enterprise platforms, and business-critical data, treating internal systems with the same rigor, reliability, and product mindset as customer-facing software. The Automation team builds human-to-system and system-to-system automations that reduce manual effort and friction across the business. We combine cloud-native services, agentic AI, and workflow orchestration to enable employees to interact with enterprise systems through intelligent, secure, and auditable automation. As a Senior Software Engineer I (Automation), you will lead the design, build, and operation of systems and workflows that directly support business execution at scale. You will own complex technical initiatives, partner with Product Managers and stakeholders on technical roadmaps, and mentor junior engineers. This full-time position reports to the Sr. Director, Development and can be located in our Bellevue, WA office, or you may work remotely from anywhere in the US where Smartsheet is a registered employer. You Will: Architect AI Agents: Take a leading role in designing Agentic Workflows using AWS Step Functions and Bedrock Agents that reason

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LA
📍 New York, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

We are investing in agentic AI and need a Senior AI Engineer to lead the design and delivery of these systems. This is a foundational hire: you will own both the agent-facing workstreams — pipelines, orchestration, conversational interfaces — and the underlying context layer that makes them reliable, including memory management, knowledge graph integration, and retrieval infrastructure. You will work closely with data engineers, project leads, and client stakeholders, and play a key role in shaping how Lynx builds and ships AI solutions at scale. What This Involves: Lead the architecture and delivery of agentic AI systems end-to-end: agents, orchestration, tool use, and multi-step reasoning workflows. Own the context layer: design and implement memory architectures (episodic, semantic, working memory) and integrate GraphRAG and knowledge graph retrieval into agentic pipelines. Build robust RAG systems — including vector retrieval, graph traversal, and hybrid search — and ensure retrieval quality through evaluation frameworks. Translate client requirements into technical designs, presenting approaches and trade-offs to both technical and non-technical stakeholders. Define standards and reusable patterns for agentic AI development that other engineers at Lynx can build on. Set up observability, evaluation, and monitoring pipelines to ensure AI systems perform correctly in production. Requirements: 5–8 years of software or ML engineering experience, with at least 2–3 years building LLM-based or agentic AI systems in production. Deep hands-on experience with agentic frameworks (LangChain, LlamaIndex, AutoGen, CrewAI, or similar) and LLM APIs (OpenAI, Anthropic, etc.). Strong understanding of agent design patterns: ReAct, planning loops, tool use, multi-agent coordination, and memory architectures. Practical experience with GraphRAG or knowledge graph-based retrieval (e.g., Neo4j, Microsoft GraphRAG) and vector databases (Pinecone, Weaviate, Qdrant, etc.). Proficiency in

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📍 United States· Remote
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. POSITION SUMMARY CVS Health Digital is looking for hands-on, passionate people who want to join a high energy and growing team to make a difference in customers lives and who want to be on the forefront of digital innovation that aims to reinvent what a pharmacy and a health care company can be in the digital world. Currently, we are seeking a Staff Software Development Engineer, who will serve as a senior technical leader on a cross-functional product team responsible for designing, developing, and delivering scalable healthcare technology solutions. You will play a critical role in driving architecture decisions, mentoring engineers, and partnering with product, UX, and business stakeholders to build secure, cloud-native applications that enhance the digital healthcare experience. In this role, you will lead the development of distributed systems and microservices leveraging Java, Spring Boot, event-driven architectures, and modern cloud technologies. This Staff Engineer will also guide data migration and interoperability initiatives, supporting healthcare integrations that enable seamless and secure exchange of clinical data across platforms. The ideal candidate combines strong software engineering expertise with a passion for innovation, technical leadership, and delivering high-quality solutions in an Agile environment. Expectations for the Role Software

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📍 Austin, Texas, United States· Full-time
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Power and Performance Validation Engineer About us Graphcore is one of the world’s leading innovators in Artificial Intelligence compute. It is developing hardware, software and systems infrastructure that will unlock the next generation of AI breakthroughs and power the widespread adoption of AI solutions across every industry. As part of the SoftBank Group, Graphcore is a member of an elite family of companies responsible for some of the world’s most transformative technologies. Together, they share a bold vision: to enable Artificial Super Intelligence and ensure its benefits are accessible to everyone. Graphcore’s teams are drawn from diverse backgrounds and bring a broad range of skills and perspectives. A melting pot of AI research specialists, silicon designers, software engineers and systems architects, Graphcore enjoys a culture of continuous learning and constant innovation. Job Summary Reporting to senior leadership within Architecture and Validation, the Power and Performance Validation Lead will drive validation strategy and execution for advanced AI compute silicon and systems. The role is responsible for leading power, thermal and performance validation activities across pre-silicon and post-silicon environments to ensure products meet efficiency, reliability and scalability expectations. This role requires strong technical expertise and collaboration across multiple engineering disciplines to deliver robust validation methodologies, scalable automation frameworks and actionable performance insights. The Team The Power and Performance Validation team sits within the Architecture and Validation organisation and is responsible for validating the performance, efficiency and thermal behaviour of Graphcore silicon and systems. The team supports the full product lifecycle, from early architectural modelling through to first silicon bring-up, characterization and production readiness. Engineers work closely with cross-functional teams globally to debug compl

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