Jobs in United States

Lead Senior Python Engineer in United States

2,582 active opportunities · Updated October 2026

Explore current lead senior python engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

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📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -95.1%

From $317K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Instacart's Enterprise Solutions team partners with North America's largest grocery and retail chains to power their digital commerce through StorefrontPro, FulfillmentPro, CarrotAds, and adjacent software products. We're seeking a Senior Director, Enterprise Delivery and Growth to serve as the leader for this software portfolio — accountable for the full retailer experience from first implementation through ongoing growth and renewal. In this highly visible, impact-driven role, you will lead three Director-led organizations — Retailer Delivery (implementations), Enterprise Architecture & Engineering (solutions architecture, technical account management, and forward-deployed engineering), and Retailer Success (post-live growth and expansion) — and own the outcomes that matter: time-to-live, implementation quality and CSAT, adoption velocity, net revenu

ReactGitAIGo
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -95.1%
Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Instacart’s Enterprise Platform team is responsible for the white-label product that enables retailers of all sizes to compete online through their own ecommerce experiences. The team is focused on platform growth and long-term retailer success — from onboarding new partners to helping them acquire, serve, and retain their end customers in ways that align with their unique brand and strategy. We are seeking a Senior Product Manager to own two important efforts: creative tools that give retailers control over their e-commerce theme and brand experience, accelerated with AI acting as the product lead for large enterprise retailers – shaping proposals, aligning complex retailer requirements, and guiding planning cycles that unlock mutual growth This role is one of the most dynamic and high leverage roles we have. It requires someone who can move fluidly

GitAIGoRust
I
📍 Minnesota, United States· Full-time· Remote
✓ High-confidence listingCompany trend -95.1%

From $265K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview Enterprise Foundations is the engineering team responsible for the architectural and integration work that allows Instacart's Retailer Platform to scale across the world's largest grocers. Our work spans omnichannel integrations — bringing products like FoodStorm catering and Caper Carts onto unified Instacart platform rails — enterprise extensibility (sandbox environments, configuration systems, retailer-facing tooling), and the cross-cutting data isolation work that allows Instacart's ML and Data Engineering teams to safely build per-retailer models on top of the platform. As Instacart's enterprise retail business expands to hundreds of partner brands and new international markets, this team's work is foundational to how the platform matures. We are seeking a Senior Engineering Manager to lead this team of ~12 engineers. You'll set the unifying technical

AWSGCPAIGo
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -95.1%

From $185K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu We are seeking a Senior SOX Manager to lead enterprise-wide programs focused on SOX compliance, IT controls, and controls transformation across modern technology environments. This role sits at the intersection of technical program management, digital risk, and engineering, requiring the ability to translate complex system architectures into scalable, audit-ready control frameworks. The Senior SOX Manager will own program strategy and execution, driving alignment across Engineering, Finance, Data, and Audit stakeholders to deliver automated, efficient, and sustainable control environments. What you'll cook up in your first year Program Strategy & Execution Lead end-to-end SOX programs, including planning, execution, and delivery across ITGCs, ITACs, and key business process controls Drive risk assessments, control scoping, te

AWSAzureGCPCI/CD
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -95.1%

From $208K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Why this role is on the menu Instacart's Strategic Finance team partners across the business to drive disciplined growth and long-term value creation. Within this group, the Retailer pod supports our Retail Partnerships organization as we expand and deepen relationships with grocers and retailers across North America. In this role you will be the finance lead for retailer deal flow—setting financial strategy, shaping pricing philosophy, and driving portfolio-level decision-making across the full lifecycle of retailer partnerships. You will develop decision frameworks, build robust models, and advise senior leaders through high-stakes negotiations that shape Instacart’s revenue and margin profile. This is an individual contributor role to start, with a clear path to people management as the team grows. This person will report to the Director of Retailer Finan

C
📍 United States· Full-time· Remote
✓ Quality checkedCompany trend -100%

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . As the Senior User Researcher on the Advanced Trade team within the Consumer & Business group, you'll be the dedicated research voice for Coinbase's most sophisticated traders. The Advanced Trade team builds and improves trading experiences for high-volume, analytical traders, competing directly with top global exchanges. You'll generate deep user empathy through mixed-methods research, directly shaping roadmap prioritization, feature design, and scalable research programs that keep the entire team embedded in trader needs. What you’ll do: Lead the UX research function for the Advanced Trade team, partnering closely with Design, Product, and Data to turn user insights into actionable product ideas and measurable impact. Conduct mixed-methods research, including interviews, usability testing,

A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $179K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: We’re looking for people who know and use Airbnb and believe in what we’re trying to accomplish. Airbnb is a marketplace that connects guests and hosts, and Payments is central to creating the trust that makes every transaction possible. The Platform team plays the role of conductor, leveraging AI prototyping to bring together engineers, designers, and data scientists to build great product experiences. Our Payments Platform Managers define and execute roadmaps for their product areas, translating organizational priorities into clear plans, requirements, and measurable outcomes. The Difference You Will Make: We are building foundational platform capabilities that require expertise and experience with digital wallets and identity services, and how they interact with payment services for our guests and hosts across the world. The Senior Platform Manager, Accounts will help shape the product vision, strategy, and roadmap for the Payment Accounts area, and lead execution of cross-functional initiatives with partner teams across Payments, Trust, Guest & Host, and Compliance. This is a highly strategic role with a mandate to define and build new platform capabilities and initiatives from the ground up. You will own how this platform scales to many different guest and host use cases, and support business outcomes on guest and host services. You will partner with a cross-functional team of engineers, designers, data scientists, marketplace businesses and operations to build and scale these capabilities. You will also work closely with external enterprise partners and identit

GitRestAIGo
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $248K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Media Foundation team builds the core platforms and infrastructure that power photo and video capture, upload, processing, storage, and delivery across Airbnb's products, at a massive global scale. We partner closely with Product, Design, Data Science, Trust, and Infrastructure teams to ensure every image and video guests and Hosts see is fast, high-quality, and reliable, from the moment a Host uploads a photo to the moment a Guest views it in search results. The Difference You Will Make: As the Senior Engineering Manager for Media Foundation, you will lead a team of engineers to build and operate Airbnb's media infrastructure, the foundation powering every photo, video, and document that users interact with on the platform. Capabilities include uploads, AI/ML transformations, distribution, and presentation within the product. You will shape the team’s vision and help steer the organization towards our larger goals. This includes day-to-day operations, technical deep dives, community engagement with internal engineering teams, and strategic planning. As the technical and organizational leader for Media Foundation, you own the reliability, scalability, and evolution of the systems that power every media interaction on the Airbnb platform from the moment a host uploads a photo to the instant a guest streams a listing video. Your experience in both media technology and people management will be essential to the maintenance, modernization, and innovation of Airbnb's media platform. You set the bar for engineering excellence, define what great looks like for your team, and crea

A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $248K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Data Stewardship team is a group of passionate data practitioners with a diverse background in analytics, data modeling, governance, compliance, and scaled data quality. We are responsible for ensuring Airbnb is meeting its compliance obligations across our data ecosystem and ensuring data consumers are able to easily identify the best data for their needs. We support the pipelines, programs, and policy-bodies that make this possible. You’ll be part of the overall Data Infrastructure organization that is responsible for online and offline data infrastructure across the company, and the components that transition data between these environments. The Difference You Will Make Set the North Star: you will define the multi-year vision for Data Governance and Data Quality that scales with our global business and evolving AI landscape. Organizational Influence: Act as a primary consultant for executive leadership on data governance, ensuring that compliance and stewardship are integrated into the data product lifecycle from day one. A Typical Day Architect Ecosystems: Lead the design of overarching data architectures that don't just solve today’s batch needs but anticipate future real-time and AI-driven requirements. Scale Best Practices: Rather than just "ensuring quality," you will define the best practices, tooling, and culture that enable data organizations to maintain high-quality data autonomously. Policy Stewardship: Lead cross-functional task forces (Infosec, Legal, Privacy) to navigate complex regulatory landscapes (like GDPR or AI Act) and translate them int

JavaSQLAIGo
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $139K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Cities team leads the work necessary to implement the regulatory products and processes needed globally to comply with regulations, and does so in a manner that also sustainably supports Airbnb’s growth. The Difference You Will Make: We are seeking an operator who is exceptionally effective, entrepreneurial, collaborative, and an excellent communicator. In this role, you will help us scale regulatory compliance strategies and programs for jurisdictions, presenting to cross-functional peers and leadership. You will be the accountable owner for compliance programs, aligning strategy and execution across disparate stakeholders. You will have an eye towards scale, testing, and iterating to further the capacity of the team. You are both scrappy and polished, enabling you to move quickly while bringing stakeholders along. Ultimately your work will support our Stays business and partnerships with jurisdictions around the world, keeping Airbnb a trusted community. A Typical Day: Develop and drive regulatory initiatives that unlock supply growth and proactively address risks Lead the development and execution of successfully scaled programs across discrete compliance verticals. Create an operational rhythm and manage cross-functional stakeholders, ensuring initiatives are on track, and maintaining project documentation Analyze strategic opportunities for risk reduction across jurisdictions, partner with Engineering, Data Science, Policy and Legal to align roadmaps, and drive successful execution with measurable impact Support strategic projects to drive efficiency and e

SQLAIGoRust
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -98.9%

From $244K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: AI and ML are at the heart of the Airbnb product. From Trust to Payments, and from Customer Service to Marketing, we rely on ML to ensure that guests and hosts have the best possible experience with Airbnb. The Core ML team is responsible for driving CSxAI (Customer Support x Artificial Intelligence) initiatives by adopting Generative AI technologies to enable an intelligent, scalable, and exceptional service experience. The team develops and enhances AI models, ML services, and tools including LLM fine-tuning and optimization, RAG/Search, LLM evaluation and testing automation, feedback-based learning, and guardrails for a wide range of applications at Airbnb. The richness of Airbnb's data, the complexity of its marketplace, and the variety innate in our product mean that we need to operate at the state of the art of AI practice. We are committed to long-term innovation to solve complex problems, and to do that we need experienced ML ​​The Difference You Will Make: In this Senior Staff role, you will set technical direction and lead execution for ML evaluation and the end-to-end data flywheel powering CSxAI products (e.g., assistive agents, issue resolution, and tooling). Your work will define how we measure quality, how we turn feedback into learning signals, and how we continuously improve models and products safely and efficiently. You will partner closely with product, engineering, design, operations to build evaluation systems that are trusted, scalable, and actionable - connecting offline metrics to online outcomes. A Typical Day: Define evaluation strategy and suc

AgileAIGoRust
A
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -98.9%

From $244K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Job: Airbnb Payments team allows any two people in the world to frictionlessly exchange money with easy to use payments services. It is a core strategy to fulfill Airbnb's belongs anywhere mission. We are building a world-class payments platform that moves billions of dollars, in 191 countries, with 75 currencies, through a complex ecosystem of payments partners. We build and maintain our own in-house global payments platform because no solution exists with the global reach needed. As the platform grows we'll be adding new payment partners, global licenses, compliance and regulation controls, and building new payment experiences for our guests and hosts. Airbnb's business grows rapidly year over year, and so does Airbnb Payments' processing volume. Payments Compliance is an essential part of the Payments organization. Without it, Airbnb can be subject to fines and even forbidden from conducting business in certain markets. As a Senior Staff Engineer and Technical Lead for the Payments Compliance organization, you would own the technical vision and architectural direction across the full Compliance engineering landscape — spanning Policy Enforcement, Identity, Screening, Auditing, and Compliance Experience. You will ensure our compliance systems are cohesive, scalable, and aligned with broader company priorities as we navigate an increasingly complex global regulatory environment. The Role: We are looking for a seasoned technical leader who can operate at the intersection of deep systems expertise and organizational influence. As a Senior Staff Engineer, you will serve as the connective tissue across Complia

JavaGitAIRuby
S
📍 Seattle, Washington, United States· Full-time
✓ Quality checkedCompany trend -94.9%

Who we are About Stripe Stripe is a financial infrastructure platform for businesses. Millions of companies—from the world’s largest enterprises to the most ambitious startups—use Stripe to accept payments, grow their revenue, and accelerate new business opportunities. Our mission is to increase the GDP of the internet, and we have a staggering amount of work ahead. That means you have an unprecedented opportunity to put the global economy within everyone’s reach while doing the most important work of your career. About the team The Support Experience group develops and applies technology at all points of the user support journey to solve customer problems at scale, keeping millions of business running and unlocking growth across Stripe’s product suite. What you’ll do As a Product Lead for Support Experience, you will be devising strategy, developing product requirements, and driving execution for critical initiatives that create a world-class support experience for all of Stripe’s customers and users. You’ll be at the forefront of applied AI, solving problems for businesses and consumers, and redefining what great can look like. You’ll be leading and growing a team of experienced Product Managers who have a track record of delivering high-impact products that elevate the support experience for Stripe’s users and our user-facing support teams. Support is a high-visibility area at Stripe, and you’ll need to be comfortable orienting company leadership around your goals. Responsibilities Own and drive the product roadmap for the future of conversational AI and human support at Stripe Shape strategy, steer product requirements, and hold a high bar for the execution of high-impact initiatives that impact key segments and top customers. Partner with Stripe’s AI teams to unlock opportunities for serving users more effectively Build strong relationships with senior leaders across Operations to continually uplevel our human support functions Grow and coach a glob

O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team We are a small and fast-moving partnerships team that shapes and executes OpenAI’s most important collaborations. Your mission is to build and lead our business with independent software vendors, from native AI companies building in our programs to technology companies taking new products to market with OpenAI’s models and products. You will help partners build, launch, and grow differentiated products while working closely with our sales and product organizations. About the Role You are a senior partnerships leader with strong judgment, high ownership, and a track record of building consequential ISV relationships. You can establish durable executive partnerships, lead complex product and commercial negotiations, and move fluently from market strategy to integration, launch, adoption, and growth. You are highly commercial, technically fluent, and comfortable operating where there is no playbook. In this role, you will: Define OpenAI’s ISV partnership strategy, priorities, segmentation, and business goals. Recruit and manage a portfolio of high-impact software partners across horizontal and vertical applications. Structure and negotiate partnerships spanning product integration, model adoption, commercial terms, distribution, and joint go-to-market. Develop joint business plans and executive governance with strategic partners. Help partners move from initial build to launch, customer adoption, expansion, and scaled consumption. Create repeatable co-build, co-sell, co-market, and marketplace motions. Serve as the voice of ISVs internally, shaping product requirements, developer experience, economics, and partner programs. Track partner pipeline, launches, adoption, consumption, customer impact, and ecosystem growth. Establish the team structure and operating model needed to scale the ISV business. You might thrive in this role if you have: 12+ years of experience in technology partnerships, business development, platform ecosystems, or enterprise softw

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI Finance ensures the organization is positioned for long-term success as we pursue our mission. The Order to Cash (OTC) team oversees the complete flow of commercial transactions from order intake and provisioning through billing, collections, and cash application — ensuring accuracy, compliance, and operational excellence in support of OpenAI’s mission to ensure artificial general intelligence benefits all of humanity. About the Role We are looking for a senior, hands-on operator to own Order Management and Billing execution across OpenAI’s cloud marketplace and partner ecosystem, including platforms such as AWS, GCP, Oracle Cloud, GovCloud, and future channels. This senior individual contributor role will translate partner requirements into scalable workflows and ensure launch readiness, accurate billing, and reliable daily execution. As a senior individual contributor within the Cloud Marketplaces team, you will own the end-to-end order-to-invoice lifecycle for your assigned portfolio. You will ensure that private offers, commercial terms, provisioning, pricing, usage, billing data, credits, settlements, and partner-specific reporting flow through our systems accurately, on time, and with audit-ready controls. You will implement and continuously improve the common cloud marketplace operating model, lead cross-functional execution for your assigned portfolio, and surface risks, requirements, and improvement opportunities. You will partner across Revenue Systems, Product, Engineering, GTM, Finance, Partner Operations, and external marketplace stakeholders. This role is critical to building the operational backbone for OpenAI’s expansion across cloud marketplaces and government-cloud channels. You will combine deep operational judgment with process and control execution, automation, clear communication, and hands-on problem solving to improve billing reliability, partner experience, customer outcomes, and financial integrity at scale. This role

AWSGCPRestAI
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