Jobs in United States

Lead Senior Sr Software Engineer Full Stack in United States

2,624 active opportunities · Updated October 2026

Explore current lead senior sr software engineer full stack jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 562 related jobs

Hiring trend

-78.6%

Job postings compared with the previous 30 days

Remote options

15.8%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 32 salary observations

A
📍 San Francisco, United States· Full-time
✓ High-confidence listingCompany trend -99%

From $156K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. About Airbnb Host Community Airbnb creates opportunities for millions of hosts to build a business, develop connections with guests and hosts, and positively impact local communities. The strength of the global Host community sets Airbnb apart. We keep hosts at the center of everything we do. The Airbnb Community team treats hosts as partners by fostering connection, supporting their development and success, and incorporating their feedback in our product and policies. About the Role The Senior Host Development Lead is an experienced leader responsible for the creation and execution of global educational programs and systems that inspire and empower Airbnb hosts to grow their business and deliver high quality hospitality. This role collaborates cross-functionally to build strategy, define scope, and lead execution of initiatives that support host onboarding, continuous learning, and long-term development throughout the host journey. Aligned with Airbnb’s highest-priority company goals, these initiatives take the form of scalable solutions—such as in-product content, webinars, workshops, articles, and online toolkits—designed to meet diverse learning styles and contexts in a way that is globally consistent and locally relevant. Each educational touchpoint is conceived as part of a broader, holistic system that shapes host success through education and recognition. Responsibilities: Drive the vision and strategy of key host education programs across the host lifecycle, from onboarding to long-term optimization. Manage the end-to-end strategy, design, and execution of scaled host education initiatives

AIGoExcelMarketing
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -99%

From $204K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Experiences team is responsible for scaling a curated, high-quality supply of unique activities hosted by local creators, iconic businesses, and operators worldwide and we're at an inflection point. How we surface Experiences is one of the biggest untapped demand levers we have. Recent signals (manual ranking outperforming the algorithm in places) point to a real gap: no one owns the demand-side merchandising strategy that sits on top of ranking. This role fills that gap. It is a biz ops and product ops hybrid focused on discoverability and merchandising: what we surface, to whom, and when. The Difference You Will Make: As a Senior Business Operations Lead, you will own the merchandising strategy, partner deeply with Supply, Product, and Engineering on ranking and personalization, and build the reporting layer that tells us whether discoverability is improving. This role sits closer to Product and Eng than the other demand roles, so comfort driving a senior product partnership and influencing a technical roadmap is essential. You will report to the Director of Business Growth for Experiences and collaborate closely with others, including our SEM/SEO/Display lead, to ensure channel strategies are coherent and non-duplicative. A Typical Day: Own merchandising & discoverability strategy Define the demand-side merchandising strategy on top of ranking: placement, sequencing, and the logic for what surfaces to which guests Push for dynamic, context-aware ranking (day of week, availability, trends, market, traveler type) and represent the demand point of view in t

SQLAIGoSEO
D
📍 San Francisco, California, United States· Full-time
✓ High-confidence listingCompany trend -88.9%

From $213K/yr

Quick readStrong listing-quality and freshness signals

Datadog is seeking a highly motivated Senior Corporate Development Lead to drive our AI product strategy, build strong relationships across the founder and VC ecosystem, and support high-impact initiatives including acquisitions, venture investments, and startup partnerships. You will be part of a small, high-visibility team that reports directly to Datadog’s Founder/CEO. The ideal candidate is passionate about AI and developer tools, comfortable rolling up their sleeves, and excited to operate in a fluid, technically demanding environment. You will support evaluations, source promising AI startups, collaborate closely with internal product and engineering leaders, and help position Datadog as the preferred partner for the next generation of founders. This role is ideal for someone who is hungry for increased responsibility, operates with authenticity and creativity, and prioritizes the company’s interests. At Datadog, we place value in our office culture - the relationships and collaboration it builds, and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Support Datadog’s AI product strategy by analyzing emerging technologies, market opportunities, and competitive dynamics. Source high-potential AI startups for acquisition, investment, or partnership, and build a strong presence across the founder and VC ecosystem. Attend meetups, conferences, and ecosystem events to expand Datadog’s visibility and pipeline opportunities. Drive workstreams across diligence, valuation, financial modeling, strategic assessment, and internal recommendations. Partner with Product and Engineering leaders to evaluate build/buy/partner opportunities aligned with Datadog’s AI roadmap. Support negotiation processes, including term sheets and partnership structures. Collaborate on integration planning with cross-functional partners after acquisitions or strategic de

RestAIGoRust
A
📍 United States· Full-time
✓ High-confidence listingCompany trend -99%

From $196K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Cities team leads the work necessary to implement the regulatory products and processes needed globally to comply with regulations, and does so in a manner that also sustainably supports Airbnb’s growth. The Difference You Will Make: As a Senior Regulatory Operations Lead, you are entrusted with shaping and steering Airbnb’s regulatory strategy by driving global high-impact regulatory initiatives. You bring deep regulatory expertise, proven strategic foresight, and operational excellence that will ensure our regulatory products not only meet evolving legal requirements, but also enable innovation, trust, and sustainable growth. In this role, you will anticipate regulatory trends, translate ambiguous mandates into scalable product solutions, and serve as a trusted advisor to senior leadership—ultimately strengthening Airbnb’s reputation and resilience in a rapidly changing regulatory landscape. A Typical Day: Strategic Regulatory Leadership: Anticipate and interpret global regulatory developments, providing strategic guidance to senior leadership on potential impacts and opportunities. Develop and implement proactive product strategies to navigate complex regulatory landscapes.​ Cross-Functional Collaboration: Partner with cross-functional teams such as Engineering and Product to implement regulatory products that address the changing landscape, and anticipate future trends .​ Regulatory Program Oversight: Design and oversee comprehensive regulatory product programs, ensuring adherence to applicable regulations, and industry standards. Monitor program effectiveness and make

N
📍 Santa Clara, United States
✓ Quality checkedCompany trend -13.7%

As one of the technology industry's most desirable employers, NVIDIA has been redefining accelerated computing, computer graphics and leading the Artificial Intelligence revolution. NVIDIA's innovation is fueled by its great technology—and amazing people. We are seeking a Senior Silicon and System Product Lead to influence, innovate and take our next generation products to the market. As part of the Silicon Solutions Team, we architect and deliver groundbreaking system solutions that integrate all aspects of the system from silicon design, software design to operations and final deployment in multiple market segments that NVIDIA serves. This position offers an unique opportunity to collaborate with multiple organizations in the company and grow your career in a high impact role. We need a passionate, hard-working and creative individual to lead the products all the way from market analysis to delivering the features on the final product. What you'll be doing: Drive product performance and power targets, trade-off features/configurations and provide innovative solutions to complex silicon and system level problems. Evaluate new market segments and use cases; translate market requirements to engineering problem statements and metrics. Innovate Performance, power, yield and quality optimizations and features for the world’s fastest power-shipping products in the GPU and SoC market segments spanning gaming, automotive, datacenter and DL/AI. Develop methodologies and requirements for multi-functional teams to drive silicon and system product features to production. Incorporate productization feedback to improve the next generation. Lead the team for feature requirements and schedule from architecture to silicon phase of projects. Work alongside system architects, designers, marketing teams, chip and board designers, software/firmware engineers, HW/S

Artificial IntelligenceAI
A
📍 United States· Full-time
✓ Quality checkedCompany trend -99%

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Our team is growing, and we want you to be part of it! You’ll join a collaborative group within Airbnb’s Chief Business Officer organization focused on expanding our Monthly Stays offering. We recruit and develop Airbnb’s global supply of high-quality stays and execute our in-market strategy to drive international growth. By building strong relationships with hosts and helping them optimize their listings and pricing, our team creates lasting host success and facilitates millions of connections between guests and hosts around the world. The Difference You Will Make: As a Senior Programs and Business Operations Lead, you will work with the Homes Leadership to develop and execute strategies to grow the success of Airbnb globally. You will also align with Homes Leadership, regional teams and cross functional teams to analyze data and deliver strategic recommendations to drive the Homes business globally. Your attention to detail, organization, ability to multitask, work on multiple priorities and work under pressure will all ensure you succeed. You should be great at understanding the needs of the airbnb community and defining levers to help them succeed in the platform. You will develop strong relationships and deliver valuable guidance to help them grow within

PE
📍 Vienna, Virginia, United States· Full-time· Hybrid
✓ Quality checked

Shape the Future with Dun & Bradstreet At Dun & Bradstreet, we believe data has the power to create a better tomorrow. As a global leader in business decisioning data and analytics, we help companies worldwide grow, manage risk, and innovate. Since 1841, businesses have trusted us to turn uncertainty into opportunity. We’re a diverse, global team that values creativity, collaboration, and bold ideas. Are you ready to make an impact and help shape what’s next? Join us! Explore opportunities at dnb.com/careers. The Senior Principal Data Scientist - AI Lead will be the point of contact for Public Sector / Government stakeholders and will be responsible for end-to-end AI solution delivery. This role will partner with U.S. government agencies on programs that depend on trusted entity data, validation, and risk insight.

P
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 Connecticut, Groton, United States
✓ High-confidence listingCompany trend +68.8%

$88.5K – $147.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY The Asset Lifecycle Management (ALM) Lead is responsible for the systematic tracking, installation, and removal of laboratory equipment throughout the entire lifecycle, from acquisition through deployment, maintenance, and final disposal. Operating within an R&D environment, this role facilitates asset preplanning, site assessments, and ensures all asset-related activities are documented, tracked, and compliant with regulatory standards. By optimizing equipment usage, managing inventory, coordinating maintenance, and driving process improvements, the ALM supports efficient and safe laboratory operations while controlling costs and enabling the lab for evolving technological requirements. This is to include but not be limited to supporting the regular updates and reconciliation of the Fixed Asset Registry (FAR) and physical inventory field activities. With input from both the customer equipment owner and the original equipment manufacturer (OEM), this role will develop the correct service program for assets within EAMS (Enterprise Asset Management System) or Pfizer’s Computerized Maintenance Management System (CMMS). Additionally, this position will be responsible for the documentation of asset maintenance activities within EAMS and support site EAMS administration requiring the review of training requirements and On the Job Training (OJT) for new resources requiring system access. The Asset Lifecycle Manager will also represent the site on various Global Workplace Experience (GWE) Communities of Practice or multi-site or global teams ensuring best practices and standards are being leveraged across the broader R&D portfolio. This position will foster and maintain working relationships with GWE, Preclinical & Translational Sciences (P&TS) Research and business operations team colleague and contractors to analyze needs, provide recommendations, and execute plans and options that ali

AIExcelProject ManagementAccounting
G
📍 California, Foster City, United States
✓ Quality checkedCompany trend -1.6%

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description The Real-World Evidence (RWE) function at Gilead is part of the Clinical Data Sciences (CDS) group within the Clinical Development organization and aims to unlock the power of Real-World Data (RWD) to help transform innovations to life-changing medicines for patients. We are seeking a Senior Director, RWE Inflammation Product Lead who will be accountable for the development and execution of the RWE strategy in support of one or more Inflammation products under development. The incumbent will serve as the key RWE subject matter expert within Gilead's lifecycle management teams for the product(s) and all its indications across the development lifecycle and serve as a strategic

Recruitment
C
📍 Farmington, Farmington, United States
✓ Quality checkedCompany trend +340.2%

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary At Aetna®, part of CVS Health, we proudly serve more than 26 million medical members through our broad range of health plan offerings. We're committed to delivering a simpler, more meaningful, and personal health care experience to each of them. As a Senior Manager Medicare Product, Vendor Management Contract Lead you will play a critical role contracting, negotiations, oversight of vendors and assisting in achieving CVS goals, work strategically together, and remain as adaptable as possible in an ever-changing environment. This role's scope of responsibility includes overseeing the following in relation to Medicare Product vendor management: Finance, Contracts, Invoicing, Negotiations, Provisioning, Aetna Medicare Supplemental & Duals benefits, Vendor relationship management, Compliance oversight, Auditing, and projects as assigned. The Senior Manager, Vendor Management Contract Lead is a high impact role. You will lead advance contract and negotiation skills, work with other partner to identify root cause, address, and resolve vendor issues, manage vendors to the contract SLAs, performance guarantees and provide insight into complex vendor problems. Responsibilities include: Work assignments involving moderately complex to complex issues where the analysis of situations or data requires an in-dep

FinanceAuditing
N
📍 Santa Clara, United States
✓ Quality checkedCompany trend -13.7%

We at NVIDIA seek an Senior Developer Relations, Automated Synthetic Chemistry Science Lead who can coordinate science streams. This role exists at the crossroads of experimental science, optimization, analytical characterization, AI modeling, laboratory automation, and data infrastructure. It demands a practitioner with a background in research who can lead interdisciplinary science teams and accelerate experimentation without compromising scientific quality. What you'll be doing: Coordinate the operating plan across research priorities, technical execution, and program achievements. Convert research objectives into experimental priorities, parameter-space development, campaign planning, and success criteria. Lead research initiatives encompassing synthetic chemistry, catalysis, process chemistry, machine learning, automated systems, and data processing. Build standardized experimental traces capturing successful and unsuccessful outcomes, metadata, quality-control signals, analytical summaries. Guide AI systems for feasibility assessment, outcome prediction, optimization, scope exploration, and campaign orchestration. Integrate automated experimentation, analytical data streams, data curation, model retraining, and campaign decisions into a closed-loop operating model. Establish science-stream governance: build reviews, decision logs, risk and dependency tracking, quality thresholds, and paths for addressing blocking issues. Prepare recurring workstream readouts for program leadership, including scientific progress, critical decisions, cross-team dependencies, resource needs, and unresolved risks. What we need to see: PhD (or equivalent experience) with 10+ years of hands-on experience in experimental science, chemical engineering, material science, robotics, a

Machine LearningAI
G
📍 California, Foster City, United States
✓ High-confidence listingCompany trend -1.6%

$157.6K – $203.9K/yr

Quick readStrong listing-quality and freshness signals

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference. Every member of Gilead’s team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we’re looking for the next wave of passionate and ambitious people ready to make a direct impact. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together. Job Description Gilead Sciences is seeking a collaborative, hands-on leader to shape and deliver the ERP capabilities for a new, next-generation bulk drug substance manufacturing facility at our Foster City site. As the site’s SAP business lead, you will translate operational needs into integrated processes across production, procurement, quality, and warehousing. Working closely with site stakeholders and the IT implementation team, you will define requirements, guide implementation, and connect SAP with other digital platforms to help create a compliant, paperless manufacturing environment. R

SapLogisticsProcurementWarehouse

Related career options

Similar roles with stronger pay

Client Service Associate

Demand 46/100 · 8 jobs

$840K – $840K/yr

Salary →
Director of Product

Demand 43/100 · 6 jobs

$382.5K – $382.5K/yr

Salary →
Physical Design Engineer

Demand 43/100 · 8 jobs

$300K – $300K/yr

Salary →
Sr. Engineer

Demand 42/100 · 7 jobs

$300K – $300K/yr

Salary →
Senior Director

Demand 38/100 · 30 jobs

$278.9K – $278.9K/yr

Salary →
Senior Product Designer

Demand 30/100 · 11 jobs

$255.7K – $255.7K/yr

Salary →
🔔

Get new lead senior sr software engineer full stack jobs in United States by email

Daily job updates · Unsubscribe anytime