Jobs in United States

Lead Systems Engineer in United States

2,547 active opportunities · Updated October 2026

Explore current lead systems engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

R
📍 New York, NY, United States· Full-time
✓ High-confidence listingCompany trend -99.2%

From $10K/yr

Quick readStrong listing-quality and freshness signals

About Ramp Ramp is building the smart infrastructure for finance teams, embedded in the transaction flow of every dollar a business spends. We automate how over $200B in annualized spend flows in and out of 70,000+ companies: authorizing payments, flagging risk, categorizing spend, and closing books. The problems are high-stakes, data-dense, and unforgiving. We hire people with high agency and high urgency. We look for slope over intercept. We care less about where you trained and more about what you’ve built. At Ramp, everyone is a builder who owns problems end to end and makes consequential decisions that shape the outcome. The median Ramp customer saves 5% and grows revenue 16% in their first year – far in excess of businesses operating without Ramp. We believe every ambitious company deserves the same. If you want to build systems that directly shape how companies move and manage billions, Ramp is the place to do it. About the Role Ramp is hiring a Business Operations Lead, Compensation & Equity to help build the next stage of our compensation function. This is a senior individual contributor role with exposure to company-level decisions and frequent partnership with the executive team and leaders across People, Finance, Legal, Talent, and the business. You will not manage a team, but you will operate as a thought partner and owner for some of Ramp's most important people and business decisions. This role works on high-judgment, high-impact questions that sit within a few steps of Ramp's senior leadership team. You will work directly on issues that affect hiring strategy, retention, performance, equity planning, international expansion, executive decision-making, and the employee experience. For the right person, this is a way to build rare expertise in compensation and equity while developing the judgment and company context to take on broader operating roles over time. You do not need to be a career compensation specialist. You do need to be analytically e

PythonSQLRestAI
R
📍 New York City, NY, United States· Full-time
✓ High-confidence listingCompany trend -99.2%

From $10K/yr

Quick readStrong listing-quality and freshness signals

About Ramp Ramp is building the smart infrastructure for finance teams, embedded in the transaction flow of every dollar a business spends. We automate how over $200B in annualized spend flows in and out of 70,000+ companies: authorizing payments, flagging risk, categorizing spend, and closing books. The problems are high-stakes, data-dense, and unforgiving. We hire people with high agency and high urgency. We look for slope over intercept. We care less about where you trained and more about what you’ve built. At Ramp, everyone is a builder who owns problems end to end and makes consequential decisions that shape the outcome. The median Ramp customer saves 5% and grows revenue 16% in their first year – far in excess of businesses operating without Ramp. We believe every ambitious company deserves the same. If you want to build systems that directly shape how companies move and manage billions, Ramp is the place to do it. About the Role Ramp is known for insane product velocity, sitting at the center of AI and finance, and saving customers meaningful amounts of time and money. Increasingly, companies come to us to understand how the best finance teams are actually operating, whether that’s our own team or the customers we serve. Right now, those conversations happen behind closed doors and Zoom windows. We want to pull them out, write them down, and make them useful to more people. We’re hiring a Finance Storytelling Lead to do exactly that. You will spend roughly half your time embedded with Ramp’s Finance team, learning what it means to run an AI-pilled finance team at a company building AI solutions for finance. The other half of your time will support customer storytelling with the finance customer in mind, working closely with Brand Communications, Sales, and Customer Marketing. For both, you’ll pull out the useful lessons and turn them into stories people want to learn from, whether that means writing in your own voice or for our CFO and Finance leadership team

RestAIGoRust
P
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -73.5%

We believe that the way people interact with their finances will drastically improve in the next few years. We’re dedicated to empowering this transformation by building the tools and experiences that thousands of developers use to create their own products. Plaid powers the tools millions of people rely on to live a healthier financial life. We work with thousands of companies like Venmo, SoFi, several of the Fortune 500, and many of the largest banks to make it easy for people to connect their financial accounts to the apps and services they want to use. Plaid’s network covers 12,000 financial institutions across the US, Canada, UK and Europe. Founded in 2013, the company is headquartered in San Francisco with offices in New York, Washington D.C., London and Amsterdam. The Compensation team designs, manages, and evolves Plaid’s compensation strategy to attract, retain, and motivate world-class talent. We make sure compensation is fair inside the company and competitive in the market. We work on programs that connect directly to Plaid’s business goals and employee experience — using data and insight to make equitable, well-informed decisions. Our work spans cash and equity program design, annual and mid-year review cycles, benchmarking, and exec comp support. In this role, you will own compensation support for specific client groups and take the lead on cycle operations and comp tooling across the team. You’ll work alongside a sharp team and closely with Plaid’s Head of Total Rewards. You’ll have clear ownership of your domain from day one, with real exposure to equity program mechanics, exec comp, and board-level deliverables. Responsibilities: Own comp support for specific client groups — offers, promos, manager/HRBP questions — with a high bar for speed and accuracy Lead configuration and rollout of annual and mid-year compensation cycles in Workday and comp tooling Manage and maintain Plaid’s comp systems: Compa, Pave, and external survey tools (Compensia, Radf

M
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Own day-to-day operations for the scanner program and scanner builds in the spa: purchasing/procurement, vendor management, receiving, inventory, and logistics. Stand up lightweight production operations as we move from prototypes to repeatable builds: build planning, kitting, work instructions, and readiness checklists. Partner with Quality to ensure the operational system supports compliance: traceability, document control, training records, NCR/CAPA workflows, and audit readiness. Drive cross-functional execution for the physical spa build-out and scanner integration: schedules, dependencies, risk register, and weekly coordination with vendors and internal teams. Own the “integration glue” across facilities + device ops: commissioning plans, acceptance criteria, and operational handoff (runbooks, maintenance, spares, escalation paths). Build and track operational metrics: cost, budget, lead times, vendor performance, build throughput, and reliability of critical subsystems. Audit of import/export documentation, management of contract renewals, regulatory compliance. What we’re looking for Proven operations leadership in hardware/medical/robotics (or similarly complex electromechanical products), including procurement and vendor management. Strong program management instincts: can run schedules, unblock cross-functional dependencies, and keep priorities clear under ambiguity. Comfort operating in quality/regulatory environments and building processes that are rigorous without slowing a small team. High ownership and bias to action: can jump between spreadsheets, docks, and the lab/site to keep the program moving. Useful experience Experience running prototype-to-production transitions (NPI, EVT/DVT/PVT-style builds, CM/EMS collaboration). Facilities / construction operations experience (GC coordination, MEP commissioning, site readiness). Familiarity with inventory systems and procurement tooling (even “simple but disciplined”).

O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Central Procurement – Hardware Operations team is building scalable, AI-enabled operating foundations for a rapidly growing hardware footprint. We help the business move quickly while maintaining the data quality and controls needed to manage financial and operational risk responsibly. As OpenAI scales across R&D, new-product introduction, manufacturing, and third-party custody models, we are building the foundations to absorb complexity without adding unnecessary friction. That means establishing practical standards, strengthening discipline where it matters, using AI thoughtfully, and continuously improving how teams manage hardware operations. About the Role We are hiring an Asset Compliance Program Lead to establish the cross-business framework that gives OpenAI reliable lifecycle visibility over hardware-related financial assets and capital equipment. You will define the controls, systems roadmap, and evidence practices needed to manage those assets within OpenAI’s financial-control scope. This is a senior individual-contributor role in Central Procurement – Hardware Operations within Finance. Distinct from sourcing and transaction execution, you will partner with hardware business units, Accounting, Financial Risk Management, Procurement, contract manufacturers, and other third-party custodians to deploy practical operating mechanisms. These mechanisms will connect how assets are purchased, built, received, moved, held, verified, and retired with the ownership, data, reporting, and evidence needed for financial governance. The role covers those assets regardless of location or custody, including manufacturing equipment and tooling, supplier- and contract-manufacturer-held assets, leased assets, and other third-party-held equipment. You will stay close to the operational details—how assets move, where records diverge, which controls are not working, and where evidence is incomplete—and use that view to strengthen processes, accountab

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team The Procurement organization enables OpenAI's mission by ensuring every dollar is spent responsibly, compliantly, and efficiently. Within Procurement, the Center of Excellence (COE) team is responsible for designing and scaling the processes, systems, governance, and operating models that enable Procurement to grow effectively alongside the business. This role partners closely with Procurement and cross-functional teams to simplify how work gets requested, routed, approved, and managed across the spend lifecycle. By combining program leadership, process design, and change enablement, we help Procurement scale while maintaining strong controls and delivering an exceptional experience for employees and business partners. About the Role As Procurement Portfolio & Delivery Lead, you will lead complex, cross-functional initiatives that span Strategic Sourcing, Procure-to-Pay (P2P), Extended Workforce, Travel & Expense, Corporate Card, Risk, Legal, Finance, and Technology teams. You will not only drive project and program execution, but also actively contribute to solution design, requirements development, process optimization, testing, rollout planning, and stakeholder alignment. This is a highly collaborative role for someone who thrives in fast-moving environments, can bring structure to ambiguity, and is equally comfortable facilitating executive discussions, building project plans, and rolling up their sleeves to help move initiatives forward. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead cross-functional procurement transformation programs spanning Strategic Sourcing, P2P, Extended Workforce, T&E, Corporate Card, Risk, and Procurement Systems. Develop and maintain the Procurement transformation roadmap, partnering across teams to identify opportunities, prioritize initiatives, map dependencies, sequence work

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team At OpenAI, our User Safety & Risk Operations (USRO) team helps protect our products and users from abuse, fraud, safety risks, and other forms of misuse. We operate at the front line of real-world safety and risk management, translating user and operational signals into timely decisions, effective interventions, and improvements to our systems. This role sits on a new team within USRO focused on building operational capacity for new, ambiguous, or fast-moving areas of work. The team helps define what needs to be built, creates the operating model to support it, and works with partner teams to make the work scalable and durable over time. As a Strategic Operations Lead, you will focus on large, cross-functional initiatives that require clear thinking, technical fluency, strong execution, and the ability to bring structure to undefined problems. About the Role We are seeking a Strategic Operations Lead to drive new and existing strategic operating builds across User Safety & Risk Operations. This is a senior IC role for someone who can turn broad, undefined priorities into clear operating models, launch plans, requirements, stakeholder alignment, documentation, reporting, and execution rhythms. This role will often support initiatives where OpenAI is developing new products or partnerships and the operating model is still being defined. These programs have a direct user safety and risk nexus because new deployment models can change what signals OpenAI can see, who owns response decisions, and how user-impacting risks are detected, escalated, and resolved. You will clarify what OpenAI owns, what partner teams own, what signals we can reliably monitor, how issues should be escalated, and how the workflow should evolve from launch support into a durable operating model. The right person is highly strategic and deeply practical. They can move from executive-level framing to detailed workflow design, stakeholder management, SOPs, launch readiness, ri

SQLAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the Team OpenAI’s Finance and Revenue Operations organization builds the commercial infrastructure that enables the business to scale with speed, discipline, and financial integrity. Deal Desk operates as the commercial strategy and governance function at the intersection of Sales, Partnerships, Legal, Technical Revenue, Finance, Order Management, Billing Operations, Product, and GTM Systems. We architect complex enterprise transactions, turn ambiguity into executable decisions, and create the guardrails that let the business move quickly with operational and financial discipline. As OpenAI’s enterprise business grows in scale and complexity, Deal Desk defines how novel commercial motions become durable operating capabilities. We convert precedent-setting deal decisions into repeatable policy, controls, workflows, and systems requirements. About the Role We are hiring a Strategic Deals & Commercial Architecture Lead to lead the structuring and governance of OpenAI’s most complex enterprise transactions. This is a senior individual-contributor leadership role for someone with exceptional enterprise deal judgment, operational rigor, and a builder mindset. You will serve as the commercial architect for high-stakes opportunities, translating ambiguous requirements into coherent deal structures, approval strategies, and executable quote-to-cash plans. Your work will shape more than individual transactions. You will establish decision principles and precedent, clarify tradeoffs, and turn recurring patterns into scalable guidance, controls, systems requirements, and enablement. You will own the commercial decision and governance layer that helps strategic opportunities move decisively while managing downstream risk across contracting, billing, revenue recognition, provisioning, reporting, controls, auditability, and customer experience. The right candidate can move seamlessly between advising on a single high-value transaction and improving the operating model be

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -83.9%

About the team The Intelligence and Investigations team seeks to rapidly identify and mitigate abuse and strategic risks to ensure a safe online ecosystem in close collaboration with our internal and external partners. Our efforts contribute to OpenAI's overarching goal of developing AI that benefits humanity. This role focuses specifically on AI Safety: understanding and mitigating risks created or amplified by increasingly capable AI systems. It is not a cybersecurity, information security, or corporate security role. The Strategic Intelligence & Analysis (SIA) team provides safety intelligence for OpenAI’s products by monitoring, analyzing, and forecasting real-world abuse, geopolitical risks, and strategic threats. Our work informs AI safety mitigations, product decisions, and partnerships, ensuring OpenAI’s tools are deployed responsibly across critical sectors. About the role We are looking for a Frontier AI Risks Lead to help us understand potential harms and misuse of AI in a time of rapid, sustained change. We seek to understand how developments in AI could intersect with misuse and abuse, accelerating existing harm areas and creating novel risks. We seek to scan available signals and use strategic foresight methodologies to enable proactive detection and mitigation of frontier AI risks. This is an AI safety role focused on frontier and systemic risks, including model misalignment, recursive self-improvement (RSI), multi-agent interaction, loss of control, runaway agents, and related emerging failure modes. In this role, you will help provide a strategic-level perspective on a range of frontier AI safety areas, producing actionable understanding of issues relevant to OpenAI’s platforms, systems, and broader mission. Utilizing mixed quantitative and qualitative methodologies, you will spot early warning signs, pull threads on potentially concerning behavior, and turn weak signals into clear, prioritized risk calls. You will focus on upstream ecosystem sc

AWSRestAIGo
O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -83.9%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI Finance is responsible for ensuring the organization is set up for success in pursuit of its mission. The Finance Program Management Office (FinPMO) is responsible for driving and scaling cross-functional finance programs and M&A integrations. FinPMO partners closely across Accounting, Strategic Finance, Corporate Development, Equity, Procurement, Treasury, Risk, and Legal to ensure financial change through M&A and other new business models is executed in a controlled, auditable, and operationally effective way. FinPMO plays a critical role in managing M&A including financial deal diligence, finance operations, post-close integrations, reporting and controls. We help quarterback the M&A process to help ensure corporate integrations are executed cleanly, risks are managed proactively, and leadership has clear deal visibility. About the Role As a M&A Finance Integration Lead, you will own and scale OpenAI’s finance integration model. This is a highly cross-functional, transactions driven role for someone who can bring structure to ambiguity, translate deal complexity into executable workplans, and drive successful M&A outcomes across multiple teams. We’re looking for someone to be the central point of accountability to oversee finance workstreams across the full M&A lifecycle. You’ll ensure integrations are executed cleanly, financial risks are mitigated early, and our books, controls, and systems remain stable as OpenAI scales. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role you will: Define and build standardized, scalable M&A finance integration frameworks. Drive consistent execution across multiple, simultaneous M&A integrations. Ensure timely, accurate M&A diligence including historical financials, revenue, equity, tax, and procurement. Lead integration planning for deal close readiness a

Artificial IntelligenceAIAccountingFinance
C
📍 United States· Remote
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Fraud, Waste, and Abuse (FWA) Analyst II identifies and develops potential healthcare fraud leads through data mining, claims analysis, and investigative research. As a key contributor to the SIU lead development process, this role evaluates provider, member, pharmacy, and ancillary healthcare billing patterns for signs of fraud, waste, abuse, and other anomalies. The Analyst II uses internal claims data, analytical tools, business rule results, and industry intelligence to assess potential FWA concerns and determine whether they warrant formal investigation. This role requires strong analytical skills, healthcare claims expertise, and the ability to translate complex data into actionable investigative leads and recommendations. Essential Responsibilities Lead Development & Fraud Detection Develop proactive and reactive leads to identify potential fraud, waste, and abuse. Generate FWA leads by mining claims databases, reporting tools, and investigative systems. Validate and refine leads generated by business rules to assess their credibility and investigative value. Examine spike analyses, utilization trends, payment anomalies, and outlier reports for unusual billing patterns. Evaluate provider, member, pharmacy, DME, transportation, and facility billing for indicators of fraud or abuse. Moni

SQLPower BiTableauAuditing
C
📍 United States· Remote
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Fraud, Waste, and Abuse (FWA) Analyst II identifies and develops potential healthcare fraud leads through data mining, claims analysis, and investigative research. As a key contributor to the SIU lead development process, this role evaluates provider, member, pharmacy, and ancillary healthcare billing patterns for signs of fraud, waste, abuse, and other anomalies. The Analyst II uses internal claims data, analytical tools, business rule results, and industry intelligence to assess potential FWA concerns and determine whether they warrant formal investigation. This role requires strong analytical skills, healthcare claims expertise, and the ability to translate complex data into actionable investigative leads and recommendations. Essential Responsibilities Lead Development & Fraud Detection Develop proactive and reactive leads to identify potential fraud, waste, and abuse. Generate FWA leads by mining claims databases, reporting tools, and investigative systems. Validate and refine leads generated by business rules to assess their credibility and investigative value. Examine spike analyses, utilization trends, payment anomalies, and outlier reports for unusual billing patterns. Evaluate provider, member, pharmacy, DME, transportation, and facility billing for indicators of fraud or abuse. Moni

SQLPower BiTableauAuditing
P
📍 New York, United States
✓ High-confidence listingCompany trend +237.5%

$106K – $176.6K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY This laboratory-based leadership role will lead upstream process development for both mammalian cell culture and microbial fermentation platforms within Vaccines Early Bioprocess Development (EBPD). The incumbent will provide scientific and people leadership for the design, planning, execution, and interpretation of experiments supporting recombinant protein and vaccine antigen production. The role requires strong expertise in upstream process development, including host and cell-line evaluation, media and feed optimization, bioreactor process development, and integration of product yield and quality considerations. The successful candidate is expected to bring deep expertise in at least one platform, mammalian cell culture or microbial fermentation, together with demonstrated knowledge of and ability to lead programs across the other platform. Responsibilities include application of high-throughput and scale-down models, Design of Experiments (DOE), process characterization and modeling, scale-up, technology transfer, and development of processes suitable for good manufacturing practice (GMP) manufacture. Experience with automated and conventional bioreactor systems, such as ambr, stirred-tank bioreactors, and rocking-motion bioreactors, is highly valued. The role requires rigorous documentation, clear communication of data and recommendations, effective cross-functional collaboration, and a proven record of scientific and team leadership. ROLE RESPONSIBILITIES · Provide scientific and people leadership for the upstream process development workstream spanning mammalian cell culture and microbial fermentation within the Vaccines EBPD Process Development group. · Lead the design, prioritization, execution, documentation, and communication of complex studies to improve cell growth, recombinant protein expression, prod

AIRecruitment
B
📍 New York, New York, United States
✓ High-confidence listing

$103K – $128K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. People Team at Brex The People team builds and sustains the culture that powers Brex. We focus on talent, growth, and the employee experience; creating an environment where high-agency individuals can thrive. From hiring to development, we design systems that grow with scale and challenge people to reach their potential. It’s a team for builders, coaches, and culture-shapers. Where you’ll work This role will be based in our New York office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a minimum of three coordinated days in the office per week, Monday, Wednesday and Thursday. As a perk, we also have up to four weeks per year of fully remote work! What You’ll Do As our People Programs Lead, you will be the face of employee onboarding, owning the entire new hire journey end-to-end to empower, equip, and enable Brex

AIAccountingFinanceLogistics
B
📍 San Francisco, California, United States
✓ High-confidence listing

$103K – $128K/yr

Quick readStrong listing-quality and freshness signals

Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. People Team at Brex The People team builds and sustains the culture that powers Brex. We focus on talent, growth, and the employee experience; creating an environment where high-agency individuals can thrive. From hiring to development, we design systems that grow with scale and challenge people to reach their potential. It’s a team for builders, coaches, and culture-shapers. Where you’ll work This role will be based in our San Francisco office. We are a hybrid environment that combines the energy and connections of being in the office with the benefits and flexibility of working from home. We currently require a minimum of three coordinated days in the office per week, Monday, Wednesday and Thursday. As a perk, we also have up to four weeks per year of fully remote work! What You’ll Do As our People Programs Lead, you will be the face of employee onboarding, owning the entire new hire journey end-to-end to empower, equip, and enable

AIAccountingFinanceLogistics
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