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Portfolio Risk Management Senior Business Lead in New York

67 active opportunities · Updated October 2026

Explore current portfolio risk management senior business lead jobs in New York. Filter by work mode, employment type, experience, department, date posted and distance.

P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$162.9K – $271.5K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. IBRANCE changed the treatment paradigm for metastatic breast cancer when it launched in 2015. As the brand approaches loss of exclusivity (LOE), this role owns its omnichannel and HCP marketing engine through the LOE timeframe and then carries that same omnichannel discipline forward to stand up NPP and digital execution for the Oncology Business Unit's next wave of breast cancer launches. This is a role for a marketing leader who thrives on solving complex problems in a competitive market and wants both halves of the brand lifecycle; defending an in-line asset through the tape, and building the omnichannel foundation a new set of launches will be built on. This individual must be able to excel in a fast-paced, matrixed environment, make immediate business impact, think outside the box, and actively contribute to a positive team culture. This role will focus on non-personal promotion (NPP), owning IBRANCE's nonpromotional strategy and digital/omnichannel execution (paid search, organic search, paid social, web analytics, search AI, media strategy,

AIExcelProject ManagementRecruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$230.9K – $384.8K/yr

Quick readStrong listing-quality and freshness signals

ROLE SUMMARY Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. The US Precision Medicine Thoracic Franchise is entering its most consequential — and most complex — growth chapter. Our in-line thoracic portfolio spans two biomarker-defined populations: LORBRENA (lorlatinib) for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC), and the BRAFTOVI + MEKTOVI (encorafenib + binimetinib) regimen for BRAF V600E-mutant metastatic NSCLC. Both sit inside a molecularly driven treatment landscape where the right patient is identified by a biomarker signature. Winning here means mastering precision targeting: reaching narrow, high-value, genomically defined patient populations through the exact clinicians who test for and treat them. This is a people-management leadership role that demands a strong enterprise leader — one fluent in both commercial strategy and AI-enabled execution, and able to think and operate at the enterprise level. The colleague who leads this team will set a multi-year strategic vision, make thoughtful trade-off and resource-prioritization decisions across two brands, and influence senior leadership across the wider organizati

Machine LearningAIExcelRecruitment
P
📍 New York, United States
✓ High-confidence listingCompany trend +671.4%

$300.1K – $500.1K/yr

Quick readStrong listing-quality and freshness signals

Role Summary This role serves as the single point of accountability between USMAPPS and the Oncology Business Unit, owning access strategy, payer marketing, and brand-level contracting and pricing strategy across the full oncology portfolio. The role drives and owns outcomes, integrating all USMAPPS capabilities into one coherent access plan that directly supports the Oncology BU President and franchise leads. The Vice President is expected to operate at full strategic weight, lead a team aligned to oncology brands and franchise clusters, and be the single person the Oncology BU holds accountable for market access results. The Vice President, US Market Access Lead – Oncology reports directly to the Senior Vice President of US Market Access & Pfizer Patient Services (USMAPPS) with a dotted line to the Oncology BU President . This position requires close partnership with the Oncology BU President, franchise leads, Strategic Contracting & Analytic s , Strategic Account Management, the Patient Services, and USMAPPS leadership. The role sits on the Oncology BU leadership team and on the USMAPPS Leadership Team. Role Responsibilities 1. Oncology Access Strategy Ownership Develop and maintain a fully integrated brand market access plan for all oncology brands, covering payer marketing, contracting strategy, and pricing strategy in one coherent plan </

AIRecruitment
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $120K/yr

Quick readStrong listing-quality and freshness signals

Datadog is seeking an Indirect Tax Manager to oversee U.S. sales and use tax compliance, support related audits, and coordinate VAT/GST obligations across our global entity portfolio. You will partner with external advisors and cross-functional teams to address evolving indirect tax requirements, strengthen controls, and embed tax considerations into business systems and processes. This role offers the opportunity to manage complex, multi-jurisdictional workstreams while helping scale a global indirect tax function. You will also expand your expertise across tax technology, e-invoicing, compliance operations, and international tax matters as Datadog continues to grow. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Review U.S. multi-state sales and use tax filings prepared by the team, ensuring accuracy and alignment with established nexus and taxability positions Support U.S. sales and use tax audits, notices, and inquiries by coordinating documentation, technical analysis, external advisors, and communications with tax authorities Coordinate VAT/GST compliance and recovery activities across Datadog’s international entity portfolio, partnering with advisors across EMEA, APAC, and LATAM Monitor changes in nexus, taxability, VAT/GST, e-invoicing, and e-reporting requirements, and communicate relevant impacts to internal stakeholders Partner with Accounting, Revenue, Legal, Procurement, and Engineering to incorporate indirect tax requirements into billing systems, ERP configurations, controls, and new market or product initiatives Develop and maintain process documentation, audit-readiness materials, workstream tracking, and SOX-aligned controls that support a scalable indirect tax function Who You Are: Experienced in progressive indirect tax roles within

D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%
Quick readStrong listing-quality and freshness signals

As a Staff Product Manager on Datadog's Observability Data Platform (ODP) , you will lead product management for a portfolio of foundational platform bets — work that changes the cost structure and capability of the platform itself, not the cost of any single feature. Among ODP’s portfolio of engineering work are efforts to bring the platform's unit cost down meaningfully each quarter, plus a slate of architectural bets aimed at order-of-magnitude cost reduction over the longer horizon. The work you'll lead reshapes how Datadog ingests, routes, and exposes telemetry value to customers — and is foundational to how every product team in Datadog's ecosystem will think about telemetry economics going forward. This role reports to the Group Product Manager of ODP. What You'll Do: Set product direction across foundational platform bets by defining problems and desired outcomes, partnering with engineering to determine slices of work that drive value in phases for users and the business. Collaborate on the long-term cost-and-value architecture of the platform — how value-aware telemetry, innovative data engines, and customer-facing cost stories fit together over multiple quarters. Develop and defend sizing and impact estimates for large, diffuse programs — credibly produce the analysis that engineering leadership and pricing partners need to make resourcing and prioritization calls. Anticipate and communicate market trends in telemetry economics and agentic observability and how they shape platform investment. Develop deep understanding of cost-to-serve by partnering with engineering on the unit economics of the data platform and bring that cost-profile understanding into collaborative discussions with product verticals about customer-facing trade-offs. Surface the customer-positive angles in cost work that engineering-led optimization tickets don't currently make visible. Deliver concise written and verbal communication to executive, engineering, and customer audien

AIGoRustSpring
N
📍 New York, NY, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

#Team Nextdoor Nextdoor (NYSE: KIND) is the essential neighborhood network. Neighbors, public agencies, and businesses use Nextdoor to connect around local information that matters in more than 350,000 neighborhoods across 11 countries. Nextdoor builds innovative technology to foster local community, share important news, and create neighborhood connections at scale. Download the app and join the neighborhood at nextdoor.com . Meet your Future Neighbors Nextdoor Account Managers are a diverse, driven, and strategic group of client services and salespeople focused on connecting brands with our community of neighbors through our growing portfolio of advertising products. The team culture mirrors the larger business focus, relying on building trusted relationships both internally as well as with our partners. The team drives results for our brand partners while creating neighbor value. We're a purpose-driven company and we're recruiting like-minded client services professionals who are as passionate about customer value as they are professional growth, and building a culture of belonging. At Nextdoor, we operate in an AI-first environment and expect every team member to actively use AI tools as part of their workflow. We aren't looking for prompt engineers; we’re looking for people who use tools like Claude, Gemini, ChatGPT, and Glean to challenge their own thinking and take full ownership of AI-assisted outputs. We also offer a warm and inclusive work environment that embraces a hybrid employment model, blending an in office presence and work from home experience for our valued employees. The hiring team will go over these expectations with you if you are being considered for a role near one of our offices in San Francisco, Los Angeles, Chicago, Dallas, New York, and London. The Impact You’ll Make Nextdoor’s Account Management team helps advertisers by connecting them with our hyper-local community of neighbors across the United States through our native a

AICustomer Service
DU
📍 New York, NY, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

About the Team Our Advertising & Promotions Marketing team operates at the intersection of e-commerce and advertising, surfacing and monetizing relevant content that benefits our core audiences. We provide digital solutions to help advertisers reach DoorDash audiences. The growing DoorDash ads business will quickly become the single best place for merchants and brands to market to local customers, in an ecosystem that benefits all parties. About the Role Our advertising business is one of the fastest-growing parts of DoorDash. This role exists to ensure our sellers are equipped with the right materials for key conversations with enterprise advertisers. You will own the sales content portfolio for our ads business and design the system that produces it. You will co-create our annual sales narrative with our platform and product marketing partners, and own translating it into the practical materials the field actually uses to win. That covers the content sellers use in front of advertisers: pitch decks, one-pagers, customer proof, and playbooks, along with the research that informs it and the governance that keeps it up to date. You will also develop content for our external advertiser training materials. You will manage a team of four marketers covering Restaurant, CPG, and agency audiences across the US, Canada, Australia, and New Zealand, supporting a field of hundreds of sellers. You will partner with Sales, Product Marketing, Revenue Enablement, Product, and business leaders to develop content. Recurring content maintenance and library administration sit with your team. This role reports to the Sr. Director, Ads Marketing. You're excited about this opportunity because you will… Build deep fluency in our ads product suite across our Restaurant and CPG offerings, including occasions and co-marketing programs, and translate that expertise into seller storytelling and content. Own the sales content portfolio and design the operating model behind it, applying bran

SQLAISalesforceExcel
M
📍 New York, United States of America, United States
✓ High-confidence listingCompany trend +1850%
Quick readStrong listing-quality and freshness signals

We anticipate the application window for this opening will close on - 30 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72&#43; million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life The Cardiac Rhythm Management (CRM) portfolio delivers therapies designed to restore, support, and protect every heartbeat through advanced pacing, defibrillation, and remote monitoring solutions. CRM's unique ability to pair proven life-saving therapies with intelligent technology gives clinicians and patients greater confidence. Clinical impact and innovation come together to improve lives through meaningful patient outcomes. Provide technical, educational, operational and sales support to assist the district in meeting Cardiac Rhythm Management (CRM) sales and customer service objectives. CRM seeks collaborative candidates who will meet our customer expectations by striving without reserve for the greatest possible reliability and quality in our products, processes, and systems by being accountable, having a voice and acting promptly. This role supports the NYC territory and requires candidates to reside within the assigned area and travel regularly to customer accounts. Clinical Specialists must be available to support urgent customer needs and participate in weekend, holiday, and occasional after-hours coverage as bus

SalesforceLogisticsRecruitmentHR
O
📍 New York, New York, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the team OpenAI’s Forward Deployed Engineering team partners with customers to turn research breakthroughs into production systems. We operate at the intersection of customer delivery and core platform development. About the Role You will define how OpenAI delivers complex systems to customers. You will own how they are built, shipped, and adopted. You’ll translate business outcomes into a technical plan, run day-to-day execution across FDEs, Researchers, and Customer Engineers, and partner with customer teams to ensure delivery supports their goals. You will focus on the Financial Services vertical, partnering with banks, asset managers, and private capital investors to deploy next-generation AI capabilities across their operations, investment processes, and portfolio companies. You will own delivery end-to-end: embedding with Financial Services customers to map workflows and success criteria, ensuring components ship on time, and leading readiness and change management for adoption. You’ll track progress, manage dependencies, make sequencing decisions, and drive 0→1 prototypes through MVP and scale. You will also share field insights with Product and Research to guide roadmap and priorities. Success will be measured first and foremost by impact - deployments that deliver measurable value against customer goals, drive adoption, and become critical to their workflows. Additional measures of success include delivery reliability (milestones hit, low reopen/churn), operating leverage (patterns reused across deployments), judgment under pressure, and product impact (field signal that shifts roadmaps/architectures). This is a high-trust, high-autonomy role. Success requires deep technical project management expertise, extreme ownership of outcomes, and an ability to immerse in customer workflows and partner with customer teams to solve complex engineering problems at pace. This role is based in New York City. We use a hybrid work model of 3 days in the office per w

Artificial IntelligenceAIExcelProject Management
D
📍 New York, New York, United States
✓ High-confidence listingCompany trend -84.7%
Quick readStrong listing-quality and freshness signals

The Senior Manager, Sponsorship Sales will own the strategy, sales, and execution of the sponsorship program for DASH, Datadog’s flagship annual conference, while also supporting sponsorship strategy and sales for global Datadog Summits. You will manage the full sponsorship sales cycle, from developing packages and prospecting through negotiation, closing, renewal, and partner experience. This role carries a sponsorship revenue target and partners closely with Events, Partner Marketing, Community, Sales, Finance, and leadership to build a scalable sponsorship program. You will have the opportunity to shape how Datadog packages, positions, and grows sponsorship offerings across its global conference portfolio. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Build and manage the sponsorship revenue plan, pipeline, and forecast for DASH, reporting progress against targets to Events and Marketing leadership while supporting sponsorship strategy and sales for global Datadog Summits. Develop and evolve tiered sponsorship packages across branding, speaking opportunities, booth space, digital assets, lead generation, and other offerings based on sponsor needs and event capacity. Manage the full consultative sales cycle, including prospecting, qualification, pitching, negotiation, closing, renewals, and expansion with new and existing sponsors, while maintaining accurate CRM and sales activity reporting. Serve as the primary commercial relationship owner for sponsors from contract through onsite delivery, orchestrating the end-to-end partner journey while Event Marketing and agency partners manage fulfillment. Collaborate with Events, Marketing, Sales, Partner Marketing, Community, and Finance on event inventory and logistics, sponsorship positioning, account str

AIFinanceLogisticsCRM
S
📍 New York, New York, United States
✓ High-confidence listingCompany trend +364.7%

$216.6K – $283.4K/yr

Quick readStrong listing-quality and freshness signals

Work Flexibility: Field-based Neurosurgical (NS) As a Regional Manager, you will lead a team supporting technologies used in cranial, spinal, and neurosurgical procedures. You will oversee sales performance, team development, and customer relationships while helping execute regional business objectives across complex healthcare environments. NS Product Portfolio: Stryker | Neurosurgical What You Will Do Lead, coach, and develop sales representatives to support achievement of regional sales objectives and territory performance goals. Recruit, hire, onboard, and develop sales talent to build and maintain a high-performing team. Build and sustain a positive, high-performing team culture by coaching employees, promoting accountability, recognizing achievements, and reinforcing organizational values and expectations. Develop and execute regional business plans aligned with sales objectives, customer needs, and market opportunities. Analyze territory performance, market trends, and customer activity to identify opportunities for growth and business development. Conduct regular field visits to provide sales coaching, performance feedback, and professional development support. Partner with cross-functional teams including marketing, finance, operations, and customer support to execute business initiatives and address customer needs. Monitor key business metrics, forecasts, and sales performance to support achievement of regional goals. What You Will Need Required Qualifications Bachelor's degree Minimum 5 years of professional sales experience. Minimum 2 years of outside sales experience. Experience developing and executing territory or regional busin

C-
📍 New York, New York, United States
✓ High-confidence listing

$120K – $150K/yr

Quick readStrong listing-quality and freshness signals

CLEAR is building THE secure identity company of the future. Our mission is to make experiences safer and easier—physically and digitally. With more than 43 million Members and a growing network of partners across the world, CLEAR's secure identity platform is transforming the way people live, work, and travel. Whether it’s at the airport, stadium, or throughout your everyday life, CLEAR unlocks the magic of frictionless experiences. CLEAR is seeking a data-driven Product Marketing Manager (B2C) to help bring new products and businesses to life across our travel portfolio. This role focuses on increasing attach rates, deepening member engagement, and expanding average revenue per subscriber (ARPU) through high-impact cross-sell and upsell strategies. Sitting at the intersection of Product, Growth, Lifecycle, Creative, and Analytics, you will shape positioning, messaging, packaging, and promotional strategy for new offerings—ensuring they are clearly differentiated, compelling, and seamlessly integrated into the member experience. You will partner with Creative, Growth, and CRM to translate those strategies into cohesive, multi-channel campaigns. This is a high-ownership role for someone who understands subscription economics, is comfortable navigating ambiguity, and knows how to drive incremental revenue while balancing long-term retention. What you'll do: Develop positioning, campaign messaging, and creative briefs that clearly articulate the value of new products Own the product marketing strategy for targeted cross-sell and upsell campaigns, partnering with Integrated Marketing and channel owners to activate across in-app, email, paid, and owned channels Partner with Lifecycle Marketing to design personalized journeys that introduce add-ons at high-intent moments in the member lifecycle Identify behavioral signals and segmentation strategies to optimize audience targeting, offer timing, messaging, and relevance Design and execute experiments to increase co

A
📍 New York, NY, United States
✓ High-confidence listing

$100K – $155K/yr

Quick readStrong listing-quality and freshness signals

Altana is the network for trusted trade. Our AI-powered product network empowers governments and businesses to build a more resilient and secure global economy while keeping trade flowing. The Opportunity at Altana As we continue to scale our Logistics business we are seeking a dynamic and experienced Account Executive to join our team in London, UK or New York, US. As an Account Executive at Altana Technologies, you'll be at the forefront of our sales initiatives, playing a crucial role in growing our footprint with Logistics Service Providers. You'll be working closely with various teams, including Account Management, Product Management, and Marketing to drive sales cycles and build new business pipelines. Your Responsibilities Develop detailed sales plans and sales forecasts Drive active sales cycles while building new business pipeline through prospecting and relationship building with mid-sized Logistics Service Providers Manage a large portfolio of Logistics Service Provider accounts from Ocean Liners to Customs Brokers. Summarize product feedback gathered from customer meetings and act as advocate for our customers with internal development and product teams Maintain up to date knowledge of logistics industry, Ability to sell across multiple Lines of Business simultaneously (IT, Procurement, Transportation, Supply Chain/Logistics), Travel to meet with clients, prospects and partners About You Experience working with a fast-growth technology company, strongly preferred 5+ years of Enterprise Software sales experience is required Passionate about the supply-chain and logistics/transportation space. Excellent presentation skills, with the ability to communicate effectively to both technical and executive audiences, whether it's an impromptu whiteboard discussion or a prepared presentation and demo. Ability to be strategic, but still roll up your sleeves to accomplish what needs to be done Highly organized with a strong sense of urgency to meet deadlines Ability

AISupply ChainLogisticsProcurement
S
📍 New York, United States· Full-time
✓ High-confidence listing

From $150K/yr

Quick readStrong listing-quality and freshness signals

Position Overview SingleStore is seeking an accomplished sales professional to join our Strategic Sales Team. In this role you will be responsible for closing new business and expanding existing business with large strategic customers. You will build and nurture C‑Suite relationships, consistently close multi‑million dollar deals, and use a value‑selling approach that ties technology to measurable business outcomes. This is an incredible opportunity to join an established, fast‑growing software company where you can over‑achieve, earning competitive compensation with uncapped commissions and accelerators. Priority will be given to pursuing and expanding opportunities that align with our Ideal Customer Profile (ICP) to maximize win rates, accelerate time‑to‑value, and increase lifetime customer value. Role and Responsibilities Develop and execute strategic territory and account plans to consistently achieve revenue targets within a defined portfolio. Lead multiple, concurrent customer sales cycles end to end, with a strong focus on new logo acquisition while managing longer, more complex deal timelines. Own and grow large, strategic customer accounts, navigating multi-stakeholder environments and managing complexity across decision-makers. Partner closely with Sales Engineering, Sales Development, and Field Marketing to drive deal strategy, pipeline generation, and execution. Build and maintain relationships with Channel partners, supporting pipeline development and co-selling efforts. Quickly develop a deep understanding of the company’s software products and clearly articulate the business value to both technical and non-technical stakeholders. Develop strong relationships with key decision-makers, influencers, and partners within your territory. Establish and maintain strong relationships with key decision-makers, influencers, and partners across assigned accounts and territory. Travel within the assigned territory as required to support customer engagement and sa

SQLGitAIGo
V
📍 New York, New York, United States· Full-time
✓ High-confidence listing

From $90K/yr

Quick readStrong listing-quality and freshness signals

VTS is the category leader in commercial real estate technology with more than 13 billion square feet managed on our platform globally. Every account in your book represents an opportunity to expand how some of the largest owners and operators in the industry leverage technology to modernize their portfolios. As an Account Manager, you will work directly with leadership while helping drive the next phase of growth at VTS. You will own expansion revenue across a portfolio of 60 to 80 SMB and lower mid market commercial real estate accounts. Your job is simple: generate and close net new revenue within your book. That means identifying whitespace, creating urgency, and running multiple deal cycles simultaneously, not waiting for opportunities to come to you. This is not a support role. Renewals and adoption are handled separately. You own the commercial motion including upsells, cross sells, and new product expansion, with a direct quota and meaningful upside for top performers. Here’s what you can expect as an Account Manager: Proactively identify expansion opportunities across your book using product usage data, account signals, and direct customer conversations. Run 30 to 60 day deal cycles across multiple accounts simultaneously. Build relationships with decision makers and navigate 1 to 3 stakeholder buying groups to close opportunities. Maintain a disciplined pipeline with accurate forecasting and clear next steps on every active deal. Partner closely with Customer Success and Sales while maintaining ownership of the commercial opportunity. Create urgency and momentum across active deals instead of reacting to inbound demand. What makes you a great fit? 2-4 years in a quota carrying B2B SaaS role across account management, SMB sales, or expansion focused customer roles. Demonstrated success sourcing and closing expansion revenue independently. Experience managing a high volume book of business with strong organizat

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