Jobs in United States

Principal Infrastructure Engineer in United States

334 active opportunities · Updated October 2026

Explore current principal infrastructure engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

B
📍 Round Lake, Illinois, United States
✓ Quality checkedCompany trend +350%

This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Your role at Baxter The Principal Systems Engineer will serve as a Product Design Owner (PDO) responsible for technical owner for the design, risk and integration of infusion pump systems and/or projects, which combine electro-mechanical hardware, embedded software, and user interface components, as well as the interface with other related EM and/or digital products. This role drives operational excellence and predictable, consistent execution in our products, and design and risk integrity and may serve as Risk Owner on some projects. The engineer is accountable for product safety, performance, reliability, usability and regulatory compliance, as well as risk. The PDO drives design decisions, manages design control activities, may be accountable for a product risk file, and collaborates across engineering disciplines and cross-functions to deliver robust, reliable, safe and innovative infusion therapy solutions. What you will be doing: Leads interdisciplinary design and development of medical products in compliance with FDA, EU MDR,

Recruitment
T
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -100%

$138.9K – $173.6K/yr

Quick readStrong listing-quality and freshness signals

Who we are At Twilio, we’re shaping the future of communications, all from the comfort of our homes. We deliver innovative solutions to hundreds of thousands of businesses and empower millions of developers worldwide to craft personalized customer experiences. Our dedication to remote-first work , and strong culture of connection and global inclusion means that no matter your location, you’re part of a vibrant team with diverse experiences making a global impact each day. As we continue to revolutionize how the world interacts, we’re acquiring new skills and experiences that make work feel truly rewarding. Your career at Twilio is in your hands. . Hiring and how we work We use Artificial Intelligence (AI) to help make our hiring process efficient. That said, every hiring decision is made by real Twilions! Also, while we are a remote-first company, you may be asked to report in person on an ad-hoc basis for team gatherings, functional off-sites or customer meetings. . See yourself at Twilio Join us as our next Principal Presales Engineer on Twilio’s ISV team! About the job This position is needed to enable our customers to build the future of communications. The Principal Presales Engineer is a critical part of the sales team focused on our ISV segment. Twilio’s Principal Presales Engineers are responsible for delivering the Technical Win and best Product Fit to our customers. They lead the technical pre-sales relationship, drive technical discovery, propose technical architectures, demonstrate the product, anticipate concerns and offer creative solutions. They build customer trust in Twilio’s solutions. Principal Presales Engineers should be comfortable engaging a CEO or sketching out an API flow on a whiteboard with customer software engineers. As a Principal Presales Engineer you will be fully autonomous. You will be capable of driving the technical side of all but the most complex opportunities independently. Furthermore, you will pr

AzureRestAIGo
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $153K/yr

Quick readStrong listing-quality and freshness signals

The Principal CRO and Web Analyst will drive the insights, measurement, and experimentation that shape Datadog’s website roadmap and improve how users discover, learn, and convert. You’ll use data to uncover opportunities, size impact, guide prioritization across high-value pages and journeys, and inform audience segmentation and personalization. This role combines analytical depth, clear storytelling, and hands-on execution across testing and optimization while shaping the experimentation culture and strategy that the broader team operates within. You’ll partner closely with Marketing, Product, and Web Engineering to deliver measurable gains in engagement and conversion. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You’ll Do: Own website analytics, KPI frameworks, and user behavior insights to inform the website roadmap Identify performance gaps using data, benchmarks, funnel analysis, and user behavior patterns Translate insights into clear recommendations, prioritization frameworks, and experimentation plans Define and scale Datadog’s web experimentation program, including testing strategy, methodology, and best practices Improve engagement and conversion through testing, optimization, segmentation, and personalization initiatives Partner with Marketing, Product, and Engineering to align experimentation with business priorities and present findings to senior leadership Who You Are: You have 10+ years of professional experience, including 6–8 years in conversion rate optimization, web analytics, experimentation, or a related field You have strong analytical and problem-solving skills, with the ability to turn data into clear narratives and decisions You have experience with user behavior data, funnel reporting, audience segmentation, and testing methodologies

GitAIRustMarketing
N
📍 Santa Clara, United States
✓ Quality checkedCompany trend -8%

We're looking for a Principal Software Engineer to join our CSP Engagements team as the technical focal point for GPU firmware and GPU system software, working directly with engineering teams of key CSP / hyperscale customers to ensure they can reliably manage, update, and operate NVIDIA GPU firmware at fleet scale. You will drive work streams with engineering teams of key CSPs/hyperscale customers to build shared understanding of GPU firmware and system software integration, incorporate their feedback into NVIDIA's feature roadmap and delivery plan, and ensure customer-side automation and recovery procedures are ready before each firmware release. Your cross-CSP visibility enables you to identify patterns in GPU firmware operational challenges that drive systemic improvements no single customer engagement could surface alone. What you'll be doing: Drive GPU firmware & siftware work streams with CSP engineering teams — ensuring they understand GPU firmware architecture (VBIOS, InfoROM, microcontroller firmware), update sequencing, recovery procedures, and GPU power management Gather and synthesize CSP feedback on GPU firmware/software — covering manageability, observability, security requirements (e.g., multi-tenancy isolation, secure boot, attestation), and performance — and champion those priorities into NVIDIA's GPU firmware/software feature roadmap and delivery plan Drive GPU firmware update orchestration for large-scale deployments — multi-GPU update sequencing, rollback strategy, failure handling, and validation across hundreds of GPUs per rack Serve as the technical focal point between NVIDIA and CSP firmware/software engineering — ensuring GPU behaviors (error recovery flows, thermal protection, power state transitions) are well-documented and accessible for customer integration Identify cross-CSP GPU SW/FW issue patterns — common update failu

Artificial IntelligenceAI
S
📍 California, United States· Full-time· Remote
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. LEAD. STRATEGIZE. TRANSFORM. JOIN US AS A PROFESSIONAL SERVICES PRACTICE MANAGER! Are you ready to own your impact at the forefront of the data revolution ? As a Services Practice Manager , you’ll be a key driver in transforming businesses through cutting-edge cloud data solutions . You’ll collaborate with top-tier clients, strategize with elite sales teams, and lead groundbreaking professional service engagements —all while working with the best minds in the industry! This role is completely remote and can be based anywhere in the Pacific or Mountain Timezone. WHY THIS ROLE? Be a Market Leader: Own and execute a strategic vision for Professional Services. Drive Meaningful Change: Work with clients to unlock the power of data and fuel digital transformations. Lead from the Front: Manage high-impact projects, ensure seamless delivery, and drive revenue growth. Collaborate with the Best: Work cross-functionally with top industry experts to shape the future of cloud data solutions. Crush Your Goals: Meet and exceed bookings, utilization, and consumption targets while delivering exceptional customer experiences . WHAT YOU’LL DO: Spearhead services sales execution and project delivery success for key accounts. Engage C-level executives to create and execute services roadmaps tha

GitAIGoRust
P
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -85.6%
Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . About the role: We’re looking for a Principal Engineer to set the technical vision and lead foundational work across Homefeed, Search, and our emerging AI Assistant experiences at Pinterest. This role sits at the intersection of relevance, ranking, retrieval, and generative AI, and will shape how hundreds of millions of Pinners discover and act on inspiration every day. You will operate as a cross-cutting technical leader: defining long-term architecture, raising the bar on ML and systems excellence, and partnering closely with product and executive leadership to drive step‑function improvements in engagement, quality, and creator value. What you’ll do: Define the long-term technical strategy and architecture for Homefeed, Search, and AI Assistant, including retrieval, ranking, personalization, and generative experiences. Drive a multi‑year road

AWSRestMachine LearningAI
D
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

$180K – $276K/yr

Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: As Principal Product Operations, you will define and scale the operating model that enables Product, Design, and Engineering to execute with clarity, rigor, and speed. This is a highly strategic, cross-functional leadership role responsible for shaping how product investments are prioritized, planned, measured, and communicated across the company. You will partner closely with exec

RestAIGoRust
D
📍 United States· Full-time
✓ High-confidence listingCompany trend -93.7%

$213.8K – $264K/yr

Quick readStrong listing-quality and freshness signals

Drata is building the trust layer between great companies - automating compliance, managing risk, and helping organizations prove trust continuously as they scale. We're Dratanauts: a global crew of 600+ professionals united by a culture that rewards integrity, ownership, and raising the bar, no matter where in the world we're working from. Why Join the Drata Team? At Drata, you're not maintaining legacy compliance software - you're building the agentic AI platform defining what trust looks like for the next generation of companies. Here's what makes the work itself worth showing up for: Problems without a playbook: You'll work at the edge of AI and security, building agentic governance, continuous compliance, and real-time trust verification to solve problems that don't have an established answer yet. You're writing it as you go. Real ownership, not just process: Our values center on owning outcomes and raising the bar, not checking boxes. You're expected to have opinions and back them. A seat at the table: Your perspective is unique and valued. Open debate and diverse viewpoints are built into how decisions actually get made here, at every level. Growth at rocketship speed: Drata is scaling fast, which means scope grows fast too. High performers get more ownership, visibility, and experience. A crew, not just coworkers: Dratanauts consistently describe a "come as you are" culture with sharp, curious people—the kind of team that makes hard problems genuinely fun to solve. See what they say here and follow us on LinkedIn for company news, employee stories, and career updates. Job Summary: We're looking for a Principal Product Marketing Manager to help drive how Drata brings products and capabilities to market. Drata's platform spans compliance automation, enterprise GRC, TPRM, trust center, and AI governance—a growing portfolio that requires coordinated, high-quality GTM execution across every launch. This is a senior role, no direct reports, high autonomy, and high

RestAIGoRust
C
📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 We’re hiring a highly influential product analytics leader who can turn ambiguous questions into sharp insight, scalable measurement, and recommendations that directly shape what we build. This person will partner closely with Product, Engineering, Design, and Growth to raise the bar on decision quality and establish a more AI-native analytics operating model. Mission Drive the product insight agenda by helping ClickUp make faster, smarter product decisions through rigorous analysis, strong product judgment, and AI-enabled analytics workflows. What You'll Do Own the product analytics agenda across product usage, activation, feature adoption, retention, and expansion, and translate open-ended business questions into structured analyses and clear recommendations Partner with Product, Engineering, and Design to define success metrics early, improve instrumentation quality, and ensure important product surfaces are measurable from launch Build reusable analysis frameworks, semantic layers, metric definitions, and self-serve resources that help product teams answer routine questions faster and more consistently Apply AI-first methods across the analytics workflow, using large language models, coding agents, and automation for tasks like query drafting, QA, validation, documentation, and first-pass synthesis while keeping human judgment at the center of final recommendations Design and interpret experiments, observational analyses, and trend investigations, including situations where data is incomplete or traditional experimentation is not feasible Surface meaningful patterns in behavioral, subscription, and

PythonSQLAWSMachine Learning
C
📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 Role Overview We’re seeking a Principal Frontend Engineer to drive the long-term technical vision for frontend engineering at ClickUp. In this role, you will lead architectural strategy across major product surfaces, solve company-wide frontend challenges, and influence how teams build and ship at scale. You will partner deeply with engineering, product, design, backend, and integrations leadership to ensure ClickUp’s frontend systems remain fast, reliable, and adaptable as the business grows. This is a hands-on technical leadership role for someone who can operate at both strategic and implementation levels, especially in a high-growth, fast-paced environment. What You’ll Do Define and drive frontend architecture strategy across product areas and platform investments Lead the design of scalable, performant systems in Angular 2+ and React that support rapid product development Solve complex cross-team technical challenges related to performance, state management, scalability, and developer productivity Partner with backend and integrations teams to shape end-to-end architecture for major features and systems Raise the bar for quality, testing, maintainability, and engineering rigor across the frontend organization Provide technical leadership on the highest-impact initiatives and unblock teams working through ambiguous or difficult problems Guide teams toward pragmatic decisions that support both speed and long-term product quality Mentor senior and staff engineers, and help shape frontend engineering culture and standards Influence roadmap and organizational decisions through strong technical judgment

TypeScriptReactAngularAWS
M
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Partner with medical image reconstruction scientists / engineers to build ML components that improve reconstruction quality, speed, robustness, or quantitative accuracy. Define training/evaluation pipelines, datasets, and metrics that map to user needs and design requirements. Productionize models: inference performance, reproducibility, monitoring for drift/regressions, and safe fallbacks. Collaborate on hybrid algorithms, incorporating physics and learned priors, denoisers, learned regularizers, and quality estimation. Help build tooling for rapid experimentation as well as rigorous verification of algorithm changes. What we’re looking for Strong applied ML experience plus comfort with signal processing / imaging or adjacent domains. Ability to move fluidly between research prototypes and production-quality systems. Strong evaluation discipline: metrics, ablations, data leakage avoidance, and reproducibility. A demonstrated track record of applying ML to physics-based or inverse problems (i.e., shipped projects, a portfolio, or publications.) Useful experience ML for imaging/inverse problems (or adjacent) with strong evaluation discipline and comfort with GPU performance constraints. Pragmatic production mindset: reproducible training/inference, regression testing, and safe deployment in high-stakes contexts. A background in computational physics or scientific computing. Leverage ML-based methods such as PiNNs and Neural Operators to solve partial differential equations arising in ultrasound simulation and imaging. Experience in Agentic-SciML is a plus. Hands-on experience with data curation for ML: building datasets from messy, real-world sources, defining ground truth, and managing labeling or simulation pipelines. Background in data assimilation: combining observations with physics-based models (Kalman filtering, variational methods, ensemble approaches, or learned variants).

M
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Act as the in-house electrical lead for Midjourney Medical: own the electrical architecture of the scanner and the technical direction for all board-level design. Own complex board design end-to-end: architecture, schematic capture, layout (high-speed digital, analog/mixed-signal, power), DFM/DFT, fabrication and assembly vendor management, bring-up, and revision control. Write firmware for embedded targets (MCU/SoC): drivers, real-time control loops, safety-relevant logic, bootloaders, and field update paths. Audit and update HDL (FPGA) code for high-throughput data acquisition, timing/synchronization, triggering, and pre-processing of ultrasound and sensor data streams. Define electrical interfaces and data contracts with software, recon/ML and mechanical teams: timing budgets, clocking/sync, signal integrity, connectors/harnessing, and failure modes. Establish electrical engineering rigor: design reviews, schematic/layout review checklists, bring-up procedures, test fixtures, and documentation suitable for a regulated medical device program (DHF, traceability, change control). Mentor and grow the electrical function; select and manage external design partners where leverage is high. What we’re looking for Deep experience designing complex boards from blank page to stable revision, including high-speed digital and analog/mixed-signal domains. Strong schematic and layout skills (Altium/KiCad or equivalent) with real signal integrity, power integrity, grounding, and EMI/EMC instincts. Solid embedded firmware background in C/C++ (and Python for tooling): peripherals, DMA, interrupts, real-time constraints, and debugging on hardware. Practical HDL experience (VHDL/Verilog/SystemVerilog) for data acquisition, timing, and streaming interfaces. Track record of owning bring-up and debug on real hardware: scopes, logic analyzers, and disciplined root-cause analysis. Technical leadership: clear trade-offs, strong written documentation, and the ability to set

PythonGitAIC++
M
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Act as the technical lead for large parts of the scanner platform: system architecture, codebase structure, and long-term maintainability. Own core runtime foundations: distributed control, state management, fault handling, and reliability. Drive engineering rigor: testability, code quality, review standards, performance regression prevention, and release processes. Build robust observability: logs, metrics, traces, and replayable diagnostics (with privacy constraints). Collaborate with hardware and recon/ML teams to define interfaces, data contracts, timing/synchronization, and failure modes. Lead complex refactors (e.g., message passing / RPC boundaries, modularization, concurrency model) without halting forward progress. What we’re looking for Deep software architecture experience for real-world systems: robotics, instrumentation, medical devices, or other complex distributed products. Strong Python and concurrency background (asyncio, multiprocessing, profiling, performance engineering). Track record of shipping systems that are observable, debuggable, and resilient. Strong technical leadership: clarity, pragmatic trade-offs, and mentoring. Useful experience Building but rock-solid systems: clear interfaces (gRPC/protobuf or equivalent), strong state modeling, and failure handling. High-leverage engineering habits on a lean team: good tests, CI, reproducible dev environments, and fast code review. Practical performance + concurrency work in Python (asyncio, profiling, multiprocessing) and comfort debugging distributed behavior. Security-minded device software: safe defaults, encrypted data paths, and disciplined handling of PII/PHI. Operational thinking: remote updates/management, excellent logging, and diagnostics that make real hardware debuggable.

PythonAIGo
S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Data Engineering - Applied Field Engineer- CA- Menlo Park- Remote Snowflake is about empowering enterprises to achieve their full potential — and people too. With a culture that’s all in on impact, innovation, and collaboration, Snowflake is the sweet spot for building big, moving fast, and taking technology — and careers — to the next level. Our Solution Engineering organization is seeking a Data Engineering Specialist to join our Applied Field Engineering team who can provide technical leadership in working with both technical and business executives in the design and architecture of the Snowflake Cloud Data Platform as a critical component of their enterprise data architecture and overall ecosystem. In this role you will work directly with the sales team to understand the needs of our customers, strategize on how to navigate winning sales cycles, provide compelling value-based demonstrations, support enterprise Proof of Concepts, and ultimately close business. You will leverage your expertise, best practices and reference architectures highlighting Snowflake’s Data Platform capabilities across data ingestion, transformation, and lakehouse workloads. You are equally comfortable in both a business and technical context, interacting with executives and talking shop with tec

PythonSQLAIGo
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