Jobs in United States

Senior Backend Software Engineer Application Development in United States

1,941 active opportunities · Updated October 2026

Explore current senior backend software engineer application development jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

Hiring demand

51/100

steady · 543 related jobs

Hiring trend

-76.9%

Job postings compared with the previous 30 days

Remote options

15.1%

Share of matching jobs listed as remote

Typical salary

$177.2K – $177.2K/yr

Based on 29 salary observations

D
📍 Massachusetts, New York, United States· Full-time
✓ High-confidence listingCompany trend -84.7%

From $192K/yr

Quick readStrong listing-quality and freshness signals

Senior Product Manager - Search Datadog’s Search team helps users – both human and agents – find answers to their questions. Search is a critical function in Datadog, and touches many product surfaces: the query editors in product homepages and dashboards, search bars for finding relevant assets, the global cmd+k navigation search, and the MCP tools that our Bits AI agent uses to respond to natural language prompts. Search is a full-stack team: owning user-facing search components, backend search ranking systems, and machine learning models to produce recommendations. The Search team is relatively new, and still growing. We have recently built out agentic search tools, and we are looking for a leader to help us expand to ambitious orchestration systems that deliver accurate results, and proactive recommendations across both keyword and semantic search. Beyond this, you’ll have room to influence how Datadog thinks about Search as a strategic surface. What you’ll do: Define and deliver how Datadog's AI agents discover the right context and tools to answer natural-language questions accurately and at scale Stay on top of industry trends in UI and agentic search experiences and capabilities Collaborate with Applied AI teams to integrate ranking, personalization, and recommendation models that scale across both human and agentic users Define and monitor KPIs for search quality, adoption, and downstream impact on user productivity; use them to drive data-informed decision making Engage directly with customers and internal product teams to deeply understand search journeys across query editors, global navigation, and natural-language agent interfaces Who you are: You have experience with search, ranking, or recommendation systems You are familiar with or very interested in MCP servers and differences between human and agentic UX You have a sharp eye for design and strong opinions on the micro-interactions — keyboard navigation, autocomplete behavior, loading

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H
📍 New York, NY, United States
✓ Quality checkedCompany trend +310%

Become a part of our caring community Most AI engineering jobs are a thin wrapper around a model API. This role is different. We build the platform that transforms millions of clinical documents into trusted, actionable data. Our systems use large language models (LLMs) to read medical records, extract structured facts, answer complex questions with citations back to the source document, and route ambiguous cases to human experts for review. Our users make decisions that impact real healthcare outcomes, so “good enough” is not good enough. Building AI systems that are accurate, reliable, auditable, and scalable is at the core of this role. As a Senior AI Applied Engineer, you will design, build, deploy, and operate production AI systems used at scale within one of the largest health insurers in the United States. You will own solutions end-to-end, from user experience and APIs to model orchestration, evaluation frameworks, infrastructure, and production operations. Why Join Us Build production AI systems where LLMs are in the critical path, not just demos or proofs of concept. Work on extraction, retrieval, agentic workflows, and human-review systems that process real healthcare data at scale. Own projects end-to-end across frontend, backend, AI orchestration, infrastructure, deployment, and operations. Solve challenging problems around accuracy, explainability, traceability, and reliability in regulated environments. Ship quickly in a small, high-impact team that embraces AI-assisted development and rigorous quality standards. Build systems that continuously improve through expert feedback, evaluations, and human-in-the-loop workflows. Key Responsibilities Design, develop, and deploy full-stack AI-powered application

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📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Design and implement secure cloud pipelines that ingest very large scan datasets (multi-terabyte), reliably and resumably. Build orchestration for GPU-accelerated reconstruction and analysis with strong retry semantics, idempotency, and cost controls. Define end-to-end data lifecycle for medical imaging: raw vs intermediate vs derived artifacts, retention policies, and reproducibility. Implement security + compliance primitives appropriate for HIPAA/PHI: encryption in transit/at rest, key management, least privilege, audit logs, and access reviews. Build operational tooling: monitoring, alerting, runbooks, and incident-driven improvements for a growing device fleet. What we’re looking for Strong experience with cloud batch/queueing/orchestration, storage systems, and data pipeline reliability. Experience shipping production systems that handle large data volumes and failure-prone networks. Practical security mindset (least privilege, secrets, audit logging) and comfort operating in compliance-constrained environments. Useful experience Building reliable data pipelines at scale (queues/orchestration, resumable uploads, GPU batch execution) with strong observability. Security + privacy by default: encryption, least-privilege access, auditing, and practical HIPAA/PHI guardrails. Owning the “boring” backend details that keep a lean team moving: schemas/migrations, cost controls, retries, and runbooks. Understanding compute tradeoffs across hardware options, and specifying appropriate cloud resources.

S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. About the Monetization team: Snowflake Marketplace serves as the vibrant hub which enables customers to do more with data. We are building a platform that empowers organizations to seamlessly discover, access, and build with datasets, applications, and AI agents. The monetization team owns the commerce layer of the Snowflake Marketplace — building the end-to-end transactional infrastructure and buyer/seller experiences that power how data and AI products are priced, purchased, and settled across Snowflake's global ecosystem. AS A SENIOR FULLSTACK ENGINEER YOU WILL: Build and own end-to-end full-stack features — from polished React-based checkout and billing UIs to the backend services that process, validate, and settle marketplace transactions at scale Design and implement robust backend APIs and services in Java or Python that handle the lifecycle of commercial transactions: entitlements, metering, invoicing, and payment orchestration Develop reusable, accessible React component libraries and frontend systems that give buyers and sellers clear visibility into usage, spend, and revenue — working closely with design to deliver intuitive experiences Contribute to the reliability, correctness, and observability of high-stakes transactional pipelines — including fraud preventio

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S
📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake is building AI BI: a new way for anyone in a company to ask questions and get accurate, auditable answers from their data, whether as visualizations or plain-language insights. We are looking for a senior+ level full-stack engineer to help build this experience end to end. This is not about recreating every long-tail feature from legacy BI tools. We are building something lightweight, composable, and understandable by AI. The goal is to help business users, analysts, and data teams move from question to answer faster, while creating a product that is robust, scalable, and delightful to use. You should be excited to work across the stack, move quickly, and make strong product and engineering tradeoffs. The ideal candidate has experience building durable systems at enterprise scale, but is also comfortable operating with startup speed and ambiguity. In this role, you will Build core product capabilities for AI-native dashboards and analytics experiences using JavaScript (React), Go, Java. Drive projects end to end across frontend, backend, architecture, and product details. Partner closely with product, design, and sister teams to deliver cohesive user experiences. Make thoughtful tradeoffs between speed, quality, and long-term maintainability. Help shape technical

JavaScriptJavaReactAI
S
📍 United States· Full-time
✓ Quality checkedCompany trend -100%

About Supabase Supabase is the Postgres development platform, built by developers for developers. We provide a complete backend solution including Database, Auth, Storage, Edge Functions, Realtime, and Vector Search. All services are deeply integrated and designed for growth. About the Role Supabase's Partnerships function is scaling fast - spanning Technology Partners, Solution Partners, Startups, and Cloud Partnerships. We're looking for a Partner Operations & Systems Lead to own the operational and technical backbone that lets this team move quickly and make decisions with good data. This is a senior, hands-on role. You'll design the systems, processes, and reporting that the whole partnerships org runs on - and, increasingly, you'll build the internal tools yourself. Supabase is investing heavily in AI-assisted development to move faster than a traditional ops build cycle allows, and this role is expected to be a leading example of that inside Partnerships. You'll report directly to the Head of Partnerships and sit alongside our regional and functional leads as a peer, with the mandate to build and enforce operational rigor across all teams. Beyond the infrastructure, we want someone who helps shape where Partnerships places its bets - not just the system that reports on them. What You'll Own Systems & Data Infrastructure Own the partner tech stack end-to-end - CRM partner objects, attribution tooling, and partner-facing portals. Design and maintain partner attribution models and the dashboards leadership uses to evaluate performance. Ensure data hygiene and consistency across partner records, deals, and touchpoints spanning all sub-functions. Process & Program Management Design and run partner onboarding, tiering, and certification programs. Own the RFC / DRI decision-making framework for the partnerships team, including how it's used and refined over time. Run deal-registration and "quarterback" account-ownership processes that keep internal teams

C
📍 Hartford, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Position Summary The Executive Director, Digital Engineering- Aetna Member Care and Journey Services is a senior technology leader responsible for setting the technical vision, architectural direction, and engineering execution for member centric services. This role leads large-scale engineering teams that build high-performance backend APIs, microservices, and cloud-native systems that power member experiences across digital, agent, provider, and partner channels. The leader ensures exceptional service stability, resiliency, innovation velocity, and alignment with enterprise user experience and operational goals. Key Responsibilities 1. Backend API & Microservices Engineering Leadership • Lead the design, development, and delivery of scalable backend systems, APIs, and microservices powering member-facing capabilities. • Define API contract standards, and integration patterns used across Member Services platforms. • Drive service modernization by adopting cloud‑native architectures, containerization, and event-driven patterns. 2. Service Stability, Observability & Resiliency • Establish standards for availability, resiliency, performance, and disaster recovery across all services. • Implement SLO/SLI/error budget frameworks, health checks, and high‑availability architectures. <p

O
📍 San Francisco, California, United States· Full-time· Remote
✓ High-confidence listingCompany trend -80.2%
Quick readStrong listing-quality and freshness signals

About the Team OpenAI’s Forward Deployed Engineering team partners with leading semiconductor companies to deploy production-grade AI systems across the entire chip design lifecycle: design, verification, and physical design. We operate at the intersection of customer delivery and core platform development, embedding deeply with customers to translate frontier model capabilities into systems that materially improve engineering workflows and accelerate innovation. Our work turns early, high-touch deployments into repeatable solution patterns, reference architectures, and evaluation practices that scale across the semiconductor ecosystem. About the Role We are seeking a highly skilled Physical Design Engineer to join our semiconductor-focused Forward Deployed Engineering team. This is a senior IC role that will begin with a strong emphasis on physical design expertise, technical judgment, advisory leverage, and customer credibility, with the expectation that the person will grow into a broader Forward Deployed Engineering role over time. In the near term, you will serve as the team’s physical design SME across semiconductor deployments: helping FDEs, Product, and Research understand backend implementation workflows, pressure-test AI-assisted solution ideas against real physical design constraints, and raise the quality of our customer-facing technical work. You will help the broader team build fluency in implementation flows, EDA tooling, signoff methodology, and the trade-offs that shape physical design decisions in practice. Over time, we expect this role to expand beyond SME support into broader FDE ownership: partnering directly with customers, shaping deployment strategy, building and iterating production-grade AI systems, driving technical workstreams, and helping turn high-touch semiconductor deployments into repeatable solutions. This is a strong fit for someone who brings deep physical design expertise today and is excited to grow into a customer-facing, syst

PythonAWSRestAI
C
📍 United States· Full-time
✓ Quality checkedCompany trend -100%

At ClickUp, we're building the future of work: the first truly converged AI workspace unifying tasks, docs, chat, calendar, and enterprise search, all supercharged by context-driven AI. We are an AI-native company. Every team member is expected to leverage AI daily, and we evaluate AI fluency as part of our hiring process. Join us and help redefine what's possible. 🚀 Role Overview We’re seeking a Principal Frontend Engineer to drive the long-term technical vision for frontend engineering at ClickUp. In this role, you will lead architectural strategy across major product surfaces, solve company-wide frontend challenges, and influence how teams build and ship at scale. You will partner deeply with engineering, product, design, backend, and integrations leadership to ensure ClickUp’s frontend systems remain fast, reliable, and adaptable as the business grows. This is a hands-on technical leadership role for someone who can operate at both strategic and implementation levels, especially in a high-growth, fast-paced environment. What You’ll Do Define and drive frontend architecture strategy across product areas and platform investments Lead the design of scalable, performant systems in Angular 2+ and React that support rapid product development Solve complex cross-team technical challenges related to performance, state management, scalability, and developer productivity Partner with backend and integrations teams to shape end-to-end architecture for major features and systems Raise the bar for quality, testing, maintainability, and engineering rigor across the frontend organization Provide technical leadership on the highest-impact initiatives and unblock teams working through ambiguous or difficult problems Guide teams toward pragmatic decisions that support both speed and long-term product quality Mentor senior and staff engineers, and help shape frontend engineering culture and standards Influence roadmap and organizational decisions through strong technical judgment

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📍 Menlo Park, California, United States· Full-time
✓ Quality checkedCompany trend -92.9%

At Snowflake, we are powering the era of the agentic enterprise. To usher in this new era, we seek AI-native thinkers across every function who are energized by the opportunity to reinvent how they work. You don’t just use tools; you possess an innate curiosity, treating AI as a high-trust collaborator that is core to how you solve problems and accelerate your impact. We look for low-ego individuals who thrive in dynamic and fast-moving environments and move with an experimental mindset — who rapidly test emerging capabilities to discover simpler, more powerful ways to deliver results. At Snowflake, your role isn't just to execute a function, but to help redefine the future of how work gets done. Snowflake is building AI BI: a new way for anyone in a company to ask questions and get accurate, auditable answers from their data, whether as visualizations or plain-language insights. We are looking for a senior+ level full-stack engineer to help build this experience end to end. This is not about recreating every long-tail feature from legacy BI tools. We are building something lightweight, composable, and understandable by AI. The goal is to help business users, analysts, and data teams move from question to answer faster, while creating a product that is robust, scalable, and delightful to use. You should be excited to work across the stack, move quickly, and make strong product and engineering tradeoffs. The ideal candidate has experience building durable systems at enterprise scale, but is also comfortable operating with startup speed and ambiguity. In this role, you will Build core product capabilities for AI-native dashboards and analytics experiences using JavaScript (React), Go, Java. Drive projects end to end across frontend, backend, architecture, and product details. Partner closely with product, design, and sister teams to deliver cohesive user experiences. Make thoughtful tradeoffs between speed, quality, and long-term maintainability. Help shape technical

JavaScriptJavaReactAI
N
📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -40%

Company Description Novo is a venture-backed fintech that simplifies banking for small businesses. Since our Fall 2018 beta launch, we've expanded offerings from free checking accounts and debit cards to lending products, business tools (invoices, bookkeeping, and more), and integrations.Today , Novo is a powerfully simple banking platform that serves over 250,000 small businesses. In addition to providing smart tools built for entrepreneurs to better run and grow their businesses, Novo has processed billions in transactions in partnership with a number of established banking partners. Our vision is to be the go-to platform serving small businesses – from launch to everyday – so business owners can focus on growing, while Novo provides seamless money movement, money storage, and access to capital. We'd like to look back 5–10 years from now and know that we helped new generations of small businesses succeed because of the work we did at Novo. Novo raised $170 million in venture capital and is backed by leading investors, including Stripes, Valar Ventures, Crosslink Capital, and Notable Capital (formerly GGV). Learn more at https://www.novo.co . Role Description Novo is seeking a highly experienced and motivated product manager to own and scale our core banking experience — the accounts, money movement, cards, and program infrastructure that power banking for over 250,000 small businesses. This role is critical to ensuring the reliability, usability, and depth of the products at the heart of Novo, supporting our rapidly expanding customer base and business operations. The ideal candidate is a hands-on product leader who can set product direction for complex, regulated financial products, partner closely with Engineering, Design, Risk, and Compliance, and work hand-in-hand with banking partners to ship reliable, secure, high-quality experiences within a dynamic, regulated fintech environment. Responsibilities Product Strategy & Leadership Own the strategy, roadmap,

N
📍 New York, New York, United States· Full-time
✓ Quality checkedCompany trend -40%

Company Description Novo is a venture-backed fintech that simplifies banking for small businesses. Since our Fall 2018 beta launch, we've expanded offerings from free checking accounts and debit cards to lending products, business tools (invoices, bookkeeping, and more), and integrations. Today, Novo is a powerfully simple banking platform that serves over 250,000 small businesses. In addition to providing smart tools built for entrepreneurs to better run and grow their businesses, Novo has processed billions in transactions in partnership with a number of established banking partners. Our vision is to be the go-to platform serving small businesses – from launch to everyday – so business owners can focus on growing, while Novo provides seamless money movement, money storage, and access to capital. We'd like to look back 5–10 years from now and know that we helped new generations of small businesses succeed because of the work we did at Novo. Novo raised $170 million in venture capital and is backed by leading investors, including Stripes, Valar Ventures, Crosslink Capital, and Notable Capital (formerly GGV). Learn more at https://www.novo.co . Role Description Novo is seeking a Senior Product Manager to own the platform surface area that connects, activates, and deepens value for small businesses in their first 90 days and beyond. This role spans our DDA onboarding to funding activation funnel, invoice workflow, external integrations ecosystem — three interconnected surfaces that together determine whether a new Novo customer becomes an engaged, transacting one. The role will also explore how to apply AI to enhance how SMBs interact with Novo. The ideal candidate is a hands-on product leader who combines platform and tooling depth with a growth mindset: someone who can own complex product workflows end-to-end, run rigorous experimentation, and is comfortable getting their hands dirty in LLMs. This is a high-impact, high-visibility role at the intersection of product

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📍 Oregon, United States· Remote
✓ High-confidence listingCompany trend +671.4%

$108.6K – $250.7K/yr

Quick readStrong listing-quality and freshness signals

Role Summary Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future. The Senior Oncology Account Specialist (SOAS) will have a variety of responsibilities, ranging from promoting Pfizer’s product portfolio to health care providers and specialists, to educating members of the healthcare community regarding the appropriate use of Pfizer products, to calling on accounts and organized customers to help improve patients’ experience with Pfizer products, as well as the overall quality of patient care delivered. The SOAS plays a critical role in increasing Pfizer’s brand with high-value target customers by linking an insightful assessment of the account and/or business landscape with a strong understanding of Pfizer’s products and resources. BASIC QUALIFICATIONS BA/BS Degree from an accredited institution BA/BS Degree from an accredited institution OR an associate’s degree with 8&#43; years of experience; OR a high school diploma (or equivalent) with 10&#43; years of relevant experience. Ability to travel domestically and stay overnight as necessary Valid US driver’s license and driving record in compliance with company

AIRecruitment
C
📍 Mount Prospect, United States
✓ High-confidence listingCompany trend +340.2%
Quick readStrong listing-quality and freshness signals

We’re building a world of health around every individual — shaping a more connected, convenient and compassionate health experience. At CVS Health®, you’ll be surrounded by passionate colleagues who care deeply, innovate with purpose, hold ourselves accountable and prioritize safety and quality in everything we do. Join us and be part of something bigger – helping to simplify health care one person, one family and one community at a time. Summary The Senior Manager, Pharmacy Operations provides strategic leadership and site-level alignment for back-end mail-order pharmacy operations. This role is responsible for driving operational excellence, financial performance, compliance, talent development, and cross-functional collaboration while supporting the successful execution of enterprise initiatives and business objectives. A Brief Overview Manages day-to-day operations of pharmacy support staff by providing strategic leadership and oversight for pharmacy support operations. Develops and implements operational strategies, establishes performance metrics, and drives process improvements to contribute to strategic decision-making regarding pharmacy support initiatives and goals. Collaborates with stakeholders, such as pharmacists and healthcare providers, to ensure effective communication, efficient workflow coordination, and adherence to quality and safety standards. Fosters a supportive and productive work environment and facilitates professional development opportunities for the team. What you will do Provide strategic leadership and oversight of all site operations to ensu

Project ManagementFinanceSupply ChainProcurement
C
📍 Jersey City New Jersey United States, United States
✓ High-confidence listingCompany trend +800%
Quick readStrong listing-quality and freshness signals

Senior Low Latency Developer – Equities Connectivity Engineer the future of global finance. At Citi, our Tech team doesn’t just support finance – we are helping to redefine it. Every day, $5 trillion crosses through our network. We do business in 180&#43; countries operating at a scale few can match. From deploying advanced AI to helping shape global markets, we build systems that matter. Look to join a team where your work helps influence economies, your ideas can drive innovation and outcomes, and your growth is backed by mentorship, continuous learning and flexibility with potential hybrid work opportunities. Help solve real-world challenges that touch millions and get the opportunity to build the future of finance with Citi Tech. Equities Technology Equities Technology at Citi is undertaking a bold, multi‑year transformation to build a best‑in‑class global platform across execution, prime, clearing and cross‑product margining. We are re‑engineering our technology estate to achieve world‑leading performance and resiliency, enabling new capabilities in advanced execution, global market connectivity, and modernized post‑trade, clearing and margin processes. Our ambition is to deliver a seamlessly integrated, highly automated platform that drives outstanding client outcomes and accelerates growth across our global franchise. As part of the team, you’ll collaborate closely with high‑caliber engineers and deeply engaged business and product partners - working together to define and deliver the next generation of Equities technology at Citi . Role Overview Citi's Equities Technology organization is seeking an experienced, hands-on engineer to join the Equities Electronic-Execution (Electronic Trading) technology team. The person in this role will be responsible for the development and operational excellence of Citi's next-generation low-latency connectivity platforms.

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