What you’ll do Design and implement secure cloud pipelines that ingest very large scan datasets (multi-terabyte), reliably and resumably. Build orchestration for GPU-accelerated reconstruction and analysis with strong retry semantics, idempotency, and cost controls. Define end-to-end data lifecycle for medical imaging: raw vs intermediate vs derived artifacts, retention policies, and reproducibility. Implement security + compliance primitives appropriate for HIPAA/PHI: encryption in transit/at rest, key management, least privilege, audit logs, and access reviews. Build operational tooling: monitoring, alerting, runbooks, and incident-driven improvements for a growing device fleet. What we’re looking for Strong experience with cloud batch/queueing/orchestration, storage systems, and data pipeline reliability. Experience shipping production systems that handle large data volumes and failure-prone networks. Practical security mindset (least privilege, secrets, audit logging) and comfort operating in compliance-constrained environments. Useful experience Building reliable data pipelines at scale (queues/orchestration, resumable uploads, GPU batch execution) with strong observability. Security + privacy by default: encryption, least-privilege access, auditing, and practical HIPAA/PHI guardrails. Owning the “boring” backend details that keep a lean team moving: schemas/migrations, cost controls, retries, and runbooks. Understanding compute tradeoffs across hardware options, and specifying appropriate cloud resources.
Jobs in United States
Senior Cloud Security Engineer in San Francisco
15 active opportunities · Updated September 2026
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15 jobs
Explore current senior cloud security engineer jobs in San Francisco. Filter by work mode, employment type, experience, department, date posted and distance.
From $183.3K/yr
About Flexport: At Flexport, we believe global trade can move the human race forward. That’s why it’s our mission to make global commerce so easy there will be more of it. We’re shaping the future of a $10T industry with solutions powered by innovative technology and exceptional people. Today, companies of all sizes—from emerging brands to Fortune 500s—use Flexport technology to move more than $19B of merchandise across 112 countries a year. The recent global supply chain crisis has put Flexport center stage as we continue to play a pivotal role in how goods move around the world. We are proud to have the support of the best investors in the game who believe in our mission, solutions and people. Ready to tackle global challenges that impact business, society, and the environment? Come join us. What you'll do There is no MSSP and no tier-1 queue here. Detection & Response engineers own their detections end to end: you write them, you tune them, and your team is paged when they fire. The security team is spread across the globe with a follow-the-sun pager rotation so nobody is paged at 3am local. The adversaries are real. The business is growing fast and the threat surface is growing with it. Defining the necessary telemetry is part of the job. Detection engineering Build and tune detections across endpoint, identity, SaaS, and cloud , treating them as software: version-controlled, peer-reviewed, and shipped through the same CI/CD practices the rest of engineering uses. Track detection quality as measured quantities : coverage against MITRE ATT&CK, precision, time-to-detect. We don’t build-and-forget here. Response & automation Own incident response: triage, contain, remediate, and write the retrospective that turns the incident into a systemic fix. Build automation that removes toil from investigations, and partner closely with the US-based team so context carries across time zones instead of getting lost at handoff. Telemetry & partnershi
About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Security team protects OpenAI’s technology, people, and products. We are technical in what we build but are operational in how we do our work, and are committed to supporting all products and research at OpenAI. Our Security team tenets include: prioritizing for impact, enabling researchers, preparing for future transformative technologies, and engaging a robust security culture. About the Role As a Security Engineer you will join our OpenAI engineers and researchers in building, operating and securing transformational AI technologies. This role will focus on all aspects of Detection & Response but with a strong emphasis on detecting insider threats and influencing controls to safeguard OpenAI's most sensitive assets. In this role, you will: In this role, you will: Innovate on Detection and Response infrastructure to engineer and automate end-to-end detection and investigation workflows. Develop, measure, and tune detection rules to ensure effective and sustainable operations. Drive projects across OpenAI’s technology stack with a focus on insider threats, ranging from access abuse and intellectual property theft to novel risks emerging within AI infrastructure. Partner closely with cross-functional stakeholders, including HR, Legal, and peer investigative teams, providing technical expertise and evidence to support investigations. Collaborate on cutting-edge AI research, and use AI to improve OpenAI’s Security posture. You might thrive in this role if you: 5+ years experience working in a detection/response or insider-risk role.. We are seeking mid-level and senior candidates. You have broad familiarity with operating systems and platforms such as macOS, Windows, Linux, and Kubernetes, along with experience in cloud infrastructure. Knowledge of modern adversary tactics and attack paths, data exfiltration techniques, and h
$192K – $240K/yr
Why join us Brex is the intelligent finance platform that enables companies to spend smarter and move faster in more than 200 markets. By combining global corporate cards and banking with intuitive spend management, bill pay, and travel software, Brex enables founders and finance teams to accelerate operations, gain real-time visibility, and control spend effortlessly. Brex’s AI-native automation and world-class service eliminate manual expense and accounting tasks for customers so they can focus on what matters most. Tens of thousands of the world's best companies run on Brex, including DoorDash, Coinbase, Robinhood, Zoom, Plaid, Reddit, and SeatGeek. Working at Brex allows you to push your limits, challenge the status quo, and collaborate with some of the brightest minds in the industry. We’re committed to building a diverse team and inclusive culture and believe your potential should only be limited by how big you can dream. We make this a reality by empowering you with the tools, resources, and support you need to grow your career. Engineering at Brex Engineering at Brex is about building systems that scale with speed and intention. Our teams span Software, Data, Security, and IT, and operate with high autonomy and deep collaboration. We tackle hard technical problems, own our outcomes, and push for excellence at every level — from architecture to deployment. It’s an environment where engineering is a craft, and builders become leaders. What you’ll do As a Security Operations Engineer at Brex, you will focus on preventing, detecting and responding to security threats across Brex's corporate and cloud environments. You will use existing systems and develop tools to improve our security capabilities. Our team is responsible for functions across corporate security, detection & response and infrastructure security domains; and we perform systems engineering and automation to support those functions. Security Operations is part of our wider Trust & IT o
From $200K/yr
We are looking for a talented engineer to lead evaluation of startup acquisition opportunities in the AI, cloud and security space. You will drive product evaluations, prepare and manage technical architecture discussions with target groups in Product and Engineering and provide roadmap suggestions for M&A and investments for Datadog. You will be a key partner to Datadog’s C-level leadership and highly visible at the most senior levels of Datadog. The role is reporting into the Senior Director of Product Strategy and falls within the Product organization. We are looking for an innovative and strategic thinker who is passionate about the latest tech being developed by startups in the cloud, AI and security space. The ideal candidate enjoys researching and evaluating new technologies, works effectively with cross-functional teams, and communicates opinions concisely to our leadership team. Broad understanding of relevant Cloud Technologies and deep understanding of the full coverage of Datadogs current offerings is necessary. The Corporate Development team is small and values authentic, strong-willed individuals who think creatively and proactively. This role leads technical due diligence from a product and architecture perspective across our acquisition pipeline. You'll scope and stand up proof-of-concept and sandbox environments to stress-test candidate products, then give an honest, unvarnished view of their quality and depth - the kind of assessment that holds up regardless of deal momentum. You'll assess technical architecture, flag the risks and open questions that matter most early, and turn that into a clear post-acquisition integration path. Working closely with engineering, you'll keep the evaluation focused on what's actually decision-relevant, then translate the findings into strategic recommendations for leadership and help carry the integration through by partnering with the right people on the other side. What You’l
About the Team Security is at the foundation of OpenAI’s mission to ensure that artificial general intelligence benefits all of humanity. The Identity Infrastructure Engineering team sits at the core of this effort, designing and building the identity and access management solutions that protect our model weights, customer data, and critical systems across multiple cloud environments. We partner with teams across OpenAI—Applied Engineering, Research, IT, and Security—to provide a secure and scalable platform for permissioning, orchestration, and innovative AI research. About the Role We’re looking for a Staff+ Software Engineer to help build and evolve the identity infrastructure that supports OpenAI’s research, engineering, and internal platforms. This role sits at the intersection of cloud infrastructure, identity systems, and software engineering. You’ll work across production systems, infrastructure-as-code, cloud control planes, identity providers, and operational infrastructure to build secure, scalable, and reliable systems used broadly across the company. The ideal candidate has experience building and operating large-scale, mission-critical systems with strong reliability and security requirements, and is comfortable writing production code, designing distributed systems, and driving ambiguous projects from 0 to 1 while building the operational rigor needed to run critical infrastructure over time. In this role, you will: Lead the architecture, development, and operation of identity infrastructure that spans cloud platforms, internal systems, and critical engineering services. Design and evolve systems for authentication, authorization, access governance, auditability, and policy enforcement with a strong focus on reliability, scalability, and secure-by-default design. Build foundational infrastructure and platform capabilities that are broadly used across engineering, research, and security teams. Improve the reliability, observability, performance, and op
About the Team OpenAI's Legal team plays a crucial role in furthering OpenAI's mission by tackling innovative, fundamental legal issues in AI. If you're passionate about doing significant and unique work as a technology lawyer, this team is for you. The team comprises professionals from diverse fields, including technology, AI, privacy, IP, corporate, employment, tax law, regulatory, and litigation. About the Role As a member of our AI Product Counsel team, you will advise the teams building and deploying OpenAI’s business products, including ChatGPT Business, ChatGPT Enterprise, and our API platform. You will partner closely with Product, Engineering, Safety, Security, Privacy, Strategy, Go-to-Market, and other Legal teams on issues spanning enterprise product development, model launches, customer data protections, administrative controls, strategic partnerships, and the responsible deployment of increasingly capable AI models. This is a unique opportunity to help shape how frontier AI products are built and delivered to businesses. This role is based in San Francisco, CA. We use a hybrid work model of three days in the office per week and offer relocation assistance to new employees. In this role, you will: Serve as a strategic legal partner to teams developing ChatGPT’s business products, enterprise features, and API offerings. Advise on product design and launches involving enterprise administration, data governance, identity and access, connectors and integrations, agentic capabilities, and voice and multimodal experiences in the B2B space. Counsel teams on deploying frontier AI capabilities responsibly while balancing customer commitments, safety, security, and privacy. Support strategic partnerships and distribution arrangements, including cloud platforms, resellers, and other third-party channels through which customers access OpenAI models. Partner with Commercial Legal, Privacy, Security, Safety, Product and Product Policy, and Go-to-Market teams on custom
About the Team OpenAI’s GTM Partnerships team builds a strategic, global partner ecosystem that accelerates customer success, enables enterprise AI adoption, and drives durable growth in support of OpenAI’s mission. Cloud partners are central to how customers discover, purchase, deploy, and scale OpenAI solutions. We work across cloud providers and their field, product, marketplace, technical, and partner organizations to reduce friction for customers and create repeatable paths from initial interest to production impact. The team collaborates closely with Sales, Technical Success, Product, Engineering, Finance, Legal, Security, Marketing, Operations, and Customer Success to turn strategic cloud relationships into measurable customer and commercial outcomes. About the Role We are hiring a Partner Director, GTM Cloud Partnerships to shape and execute OpenAI’s go-to-market strategy with strategic cloud partners. You will own senior relationships across a portfolio of cloud providers and develop joint business plans that expand customer access to OpenAI’s products, generate partner-sourced opportunities, and accelerate enterprise adoption. You will translate company-level partnerships into practical field motions spanning account planning, co-selling, cloud marketplaces, customer procurement, technical enablement, solution development, and executive engagement. This is a highly strategic and hands-on role. Success requires executive presence, strong commercial judgment, cloud ecosystem expertise, and the operating discipline to coordinate complex initiatives across multiple partners, regions, and internal teams. The ideal candidate can move fluidly between long-term strategy and the detailed execution required to deliver measurable results. This role is based in San Francisco. We use a hybrid work model of three days in the office per week. In this role, you will: Own the strategic and commercial relationships with a top global cloud partner, establishing strong alignm
About the Team The Product & Platform teams at OpenAI are responsible for delivering the company’s most impactful offerings—such as ChatGPT, our API platform, and new enterprise capabilities—to a global and diverse customer base. These systems must perform at scale and deliver exceptional experiences to developers, consumers, and businesses alike. Technical Program Managers at OpenAI play a key leadership role in scaling these efforts, partnering deeply with product, engineering, design, and go-to-market teams to bring ambitious ideas to life and ensure clarity and discipline in execution. About the Role We are hiring a Technical Program Manager to support OpenAI's critical AI deployments across strategic cloud partners. This role is designed for a candidate who can operate as an end-to-end owner across internal engineering teams and external partner organizations. This role will drive the technical strategy and execution required to bring OpenAI models and platform capabilities into partner environments responsibly and at scale. The work spans engineering deliverables, shared roadmaps, model launch pipelines, technical integration, launch readiness, and post-launch follow-through. You will work closely with senior leaders across OpenAI engineering, infrastructure, product, safety, security, legal, finance, and go-to-market, as well as technical counterparts at our partners. The job is to turn broad partnership commitments into concrete execution plans, align both sides on what must land, and build repeatable mechanisms for launching OpenAI capabilities on third-party platforms. This role is based in San Francisco, CA. We use a hybrid work model of 3 days in the office per week and offer relocation assistance to new employees. In this role, you will: Lead end-to-end execution for major cloud partner programs spanning model deployment, product integration, operational readiness, launch follow-through, and partner-platform adoption. Own integrated technical roadma
About Appier Appier (TSE: 4180) is an AI-native Agentic AI as a Service (AssA) company that empowers businesses to create value through cutting-edge AdTech and MarTech solutions. Founded in 2012 with the vision of “Making AI Easy by Making Software Intelligent,” Appier helps businesses turn AI into ROI through its Ad Cloud, Personalization Cloud, and Data Cloud—each powered by Agentic AI that enables autonomous, adaptive, and real-time decision-making. Today, Appier operates 17 offices across APAC, the US, and EMEA, and is listed on the Tokyo Stock Exchange. Learn more at www.appier.com . About the role This is a hunter sales role where you will proactively prospect and close clients for our AD Cloud solutions. You can work remotely anywhere in the U.S. We are looking for a wide range of Account Executive up to Director level talent interested in individual contributor hunter sales. Responsibilities Proactively contact new and existing clients and educate, propose and secure buy-in on Appier’s ads solutions Identify, propose and sell programs to targeted organizations within the target markets/sectors set out by the company Develop an understanding of client’s business, products, services, customer profile, marketing and business objectives, competitors and sales. Develop strategic relationships by identifying key new business opportunities About you Experience in digital media sales Good understanding on Digital & Mobile marketing industry Excellent negotiation skills with a proven track record of sales success Good interpersonal skills, initiative and follow through Ability to “translate” complex technology processes into meaningful solutions that address business needs Ideal experience selling in Ecomm vertical #LI-Remote #LI-BD1
Who Are We? Postman is the world’s leading API platform, used by more than 45 million+ developers and 500,000 organizations, including 98% of the Fortune 500. Postman is helping developers and professionals across the globe build the API-first world by simplifying each step of the API lifecycle and streamlining collaboration—enabling users to create better APIs, faster. The company is headquartered in San Francisco and has offices in Boston, New York, Austin, Tokyo, London, and Bangalore - where Postman was founded. Postman is privately held, with funding from Battery Ventures, BOND, Coatue, CRV, Insight Partners, and Nexus Venture Partners. Learn more at postman.com or connect with Postman on X via @getpostman. P.S: We highly recommend reading The "API-First World" graphic novel to understand the bigger picture and our vision at Postman. The Opportunity As a Senior Backend Engineer on the Cloud Platform team, you will play a key role in building the core systems and services that power Postman’s internal platform. You’ll help create new backend services that manage how we deploy, scale, and operate our infrastructure and product services, leveraging Java, Spring Boot, and Hibernate (JPA) on top of cloud-native technologies like Kubernetes, ArgoCD, Istio, and Terraform. This role is highly impactful: the systems you build will be used across Postman engineering, enabling faster delivery, better scalability, and a stronger developer experience. You’ll also have the opportunity to contribute to open source, shaping tools that extend beyond Postman’s boundaries. What You’ll Do Design and develop backend services in Java and Spring Boot to support Postman’s internal Cloud Platform. Architect new services that manage service deployment, lifecycle, and scaling across Kubernetes clusters. Implement GitOps workflows (ArgoCD) to support continuous delivery. Integrate with cloud-native tooling such as Istio, Helm, and Terraform. Apply strong soft
About the Team OpenAI Finance ensures the organization is positioned for long-term success as we pursue our mission. The Order to Cash (OTC) team oversees the complete flow of commercial transactions from order intake and provisioning through billing, collections, and cash application — ensuring accuracy, compliance, and operational excellence in support of OpenAI’s mission to ensure artificial general intelligence benefits all of humanity. About the Role We are seeking a Senior Manager to build and scale Order to Cash across OpenAI’s API and ChatGPT businesses, cloud marketplaces, and strategic partnership channels. This role will own end-to-end Order Management and Billing operations across API and ChatGPT while leading OTC readiness and execution for AWS Marketplace, Google Cloud Marketplace, Oracle Cloud Marketplace, GovCloud, and future partner channels. The role will also own the end-to-end Order Management and Billing close, setting the close calendar, readiness standards, review and sign-off expectations, while leading the team responsible for execution. You will oversee the Order Management and Billing lifecycle across API, ChatGPT, marketplace, and partner transactions, spanning commercial readiness, order intake, provisioning, usage and transaction data, pricing validation, invoicing, credits, settlements, and product and partner reporting. Your work will ensure transactions are accurate, timely, complete, and supported by audit-ready controls. This is a leadership role that combines strategic ownership, cross-functional leadership, and hands-on operational execution. You will define the target operating model, lead first-of-kind launches, shape product and systems roadmaps, and oversee the resolution of complex contract modifications, non-standard pricing, usage disputes, reconciliation breaks, settlement variances, and customer- or partner-impacting escalations. You will collaborate with teams across Finance, GTM, Product, Engineering, Legal, Tax, Reven
About the Role We are looking for a senior partner success and learning professional to activate cloud partners to co-sell and deploy customer solutions at scale. This role leads the enablement strategy and execution that equip partner teams to turn joint priorities into measurable customer and business outcomes. As a trusted advisor to strategic partners, you will turn shared business priorities into practical enablement programs that help partner sales, technical, customer success, and leadership teams identify joint opportunities, co-sell effectively, and deploy customer solutions successfully. You will own the partner enablement relationship for an assigned portfolio and work across internal teams to ensure programs are coordinated, scalable, and connected to measurable partner, customer, and business outcomes. This is not a traditional training delivery role or a quota-carrying partner account manager position. It is a consultative, partner-facing role for someone who can shape strategy, build relationships, translate complex AI capabilities into effective learning experiences, lead persuasive enablement sessions, and guide strategic partners toward sustained success. In this role, you will: Own strategic partner enablement and success Serve as the primary enablement and success lead for a portfolio of strategic cloud platforms. Develop a deep understanding of each partner’s business, priorities, audiences, existing learning infrastructure, and strategic relationship with our company. Build partner-specific enablement strategies aligned to shared goals, priorities, and the broader partnership strategy. Establish trusted relationships with partner leaders, alliance teams, enablement stakeholders, sales organizations, technical communities, and post-sales teams. Lead ongoing planning conversations, enablement reviews, stakeholder check-ins, and executive updates that keep partners and internal teams aligned. Identify gaps, risks, opportunities, and emerging partn
$155K – $400K/yr
About Sentry Software runs the world and the pace is faster than ever. Sentry helps developers fix errors and performance issues before users notice, so teams can spend less time firefighting and more time building. Trusted by 200,000+ organizations, Sentry is today’s application monitoring standard and our team is building its AI-native future. About the role Sentry provides tools that help developers find and fix issues in their applications. The Developer Infrastructure team owns the systems that make every engineer at Sentry more effective at shipping high quality software: developer environments, CI/CD for our open source and closed source codebases, the golden path for building new services, our SDK and library publishing tooling, and the metrics and dashboards that keep it all healthy. Our goal is straightforward: developers should spend their time thinking about the software they build for customers, not the software they use to build it. That means everything from local and cloud development environments, to the CI/CD pipeline that gets code out safely and quickly, to the tooling that catches flaky tests before they cost someone a day. As AI coding agents become part of how engineers work, we're also investing in making sure our environments, CI, and deployment systems support that shift. As a Software Engineer on Dev Infra, you'll help build and scale this infrastructure end to end. In this role, you will Build and maintain the tooling that powers local and cloud-based developer environments Improve CI for our codebases and CD for our deployment pipeline, keeping both fast and reliable as the org and its infrastructure grow Define and evolve the golden path for building new services and libraries at Sentry Contribute to our SDK and library publishing tooling and release processes Build the metrics, dashboards, and flaky test detection that give the org visibility into deployment health and CI reliability Build tooling that gives engineers, and the AI codin
About the Team At OpenAI, our User Safety & Risk Operations (USRO) team helps protect our products and users from abuse, fraud, safety risks, and other forms of misuse. We translate real-world user and operational signals into timely decisions, practical interventions, and improvements to our products and systems. This role will take on new, ambiguous, or underdeveloped operational risks and help mature them into scalable capabilities. We work across USRO and partner closely with Product, Engineering, Data Science, Product Policy, Legal, Safety, Support, and external vendors or partnership stakeholders. About the Role We are seeking a Senior Operations Analyst to take on complex, ambiguous safety and risk problems and turn them into practical operational solutions that can scale. This is a senior individual-contributor role for a versatile operator who is comfortable moving between queues, investigation, analysis, workflow design, hands-on execution, and cross-functional leadership. Depending on team needs, the role may focus on emerging-risk incubation, cloud deployment partnerships, or other new operational areas. You will be expected to move quickly, work hands-on, and create structure without waiting for perfect requirements or a large support team. The work starts with the problem, not a prescribed process. You may investigate unstructured user signals, stand up a lightweight workflow, build an AI-assisted tool, improve an existing operation, or help a new launch become operationally ready. The goal is to produce durable systems that other people can run, not simply complete a series of individual tasks. The portfolio will change with company priorities and may span established harm areas, emerging-risk incubation, cloud deployments and partnerships, device safety, or new product launches. Some hires may focus primarily on cloud deployment operations, including launch readiness, partner coordination, safety workflows, and operational monitoring. You will ty
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