Jobs in United States

Senior It Systems Engineer in United States

2,161 active opportunities · Updated October 2026

Explore current senior it systems engineer jobs across United States. Filter by work mode, employment type, experience, department, date posted and distance.

P
Relocation support. Relocation assistance is stated. This does not establish visa sponsorship.
📍 San Francisco, United States· Full-time· Remote
✓ High-confidence listingCompany trend -86.4%

From $164.7K/yr

Quick readStrong listing-quality and freshness signals

About Pinterest: Millions of people around the world come to our platform to find creative ideas, dream about new possibilities and plan for memories that will last a lifetime. At Pinterest, we’re on a mission to bring everyone the inspiration to create a life they love, and that starts with the people behind the product. Discover a career where you ignite innovation for millions, transform passion into growth opportunities, celebrate each other’s unique experiences and embrace the flexibility to do your best work. Creating a career you love? It’s Possible. At Pinterest, AI isn't just a feature, it's a powerful partner that augments our creativity and amplifies our impact, and we’re looking for candidates who are excited to be a part of that. To get a complete picture of your experience and abilities, we’ll explore your foundational skills and how you collaborate with AI. Through our interview process, what matters most is that you can always explain your approach, showing us not just what you know, but how you think. You can read more about our AI interview philosophy and how we use AI in our recruiting process here . As a Senior Product Manager for Signal Lifecycle within Trust & Safety, you'll own the product strategy for the ML platform that powers how Pinterest trains, evaluates, deploys, and measures content safety models at scale. You'll lead the development of ML Signal Management — making ML signals first-class entities with unified metadata and identity across systems. Partnering deeply with ML engineering, data science, content safety, and enforcement systems, you'll drive a platform whose scope is expanding from T&S into content quality, ads safety, and beyond. What you'll do: Own and drive the Signal Lifecycle product roadmap, including ML Flywheel infrastructure, auto-deployment, model onboarding, golden dataset management, and signal performance measurement Define and ship ML Signal Management — a unified backbone that elevates ML

SQLAWSRestAI
O
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -84.1%

About the Team OpenAI’s GTM Data Science team helps shape how our products are adopted, monetized, and scaled across organizations. We work at the intersection of Product, Go-to-Market, Finance, Research, and Data, turning product usage, customer evidence, and market signals into decisions that grow durable enterprise value. We’re looking for a senior Data Scientist to own the analytical strategy for enterprise knowledge-worker adoption. As ChatGPT Work and Codex become capable of research, analysis, document creation, spreadsheets, presentations, internal knowledge synthesis, and other agentic workflows, you will help determine how these products become embedded in everyday work—not merely tried once. About the Role You will define how we measure activation, retained usage, workflow depth, and value across ChatGPT Work, Codex, and connected enterprise systems. You will explain why adoption succeeds or stalls and identify the product, enablement, and commercial interventions most likely to create durable usage. This is a hands-on, zero-to-one role. You will work through imperfect telemetry, overlapping product surfaces, evolving definitions, and ambiguous business questions. You will partner closely with GTM, Product, Finance, Research, Customer Deployment, Analytics Engineering, and Data Science. Your work is successful when it changes a product, GTM, or investment decision. In This Role, You Will Define a trusted measurement framework for knowledge-worker adoption, including identity, eligible populations, activation, retained usage, penetration, workflow depth, feature adoption, and monetization. Map the knowledge-worker journey from initial exposure through first successful task, repeated workflows, multi-surface usage, and durable adoption. Identify which personas, functions, use cases, product capabilities, and account conditions are associated with deep and retained usage. Design and evaluate experiments and quasi-experiments across onboarding, enablement, wo

PythonSQLAWSRest
G
📍 California, El Segundo, United States
✓ High-confidence listingCompany trend +5.2%

$115.3K – $149.2K/yr

Quick readStrong listing-quality and freshness signals

We’re here for one reason and one reason only – to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We’ve made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet. Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next. We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows. Job Description Position Summary The Senior IT Quality Engineering Specialist serves as the technical lead for the Kite Laboratory Information Management System (KLIMS) within North America West Coast (El Segundo). This role is responsible for the operational stability, compliance, maintenance, enhancement, and technical governance of the LabVantage platform and associated integrations. The position partners closely with Quality Control, Manufacturing, Validation, Infrastructure, and Kite Business stakeholders to ensure reliable and compliant laboratory operations. Key Responsibilities System Administration & Operational Support • Provide day-to-day administration and technical support for KLIMS and related

JavaSQLRecruitment
M
📍 San Francisco, California, United States· Full-time
✓ Quality checkedCompany trend -100%

What you’ll do Be the generalist EE for the scanner system: integration, bring-up, debugging, and making the electrical side of the device reliable and serviceable. Own ultrasound experimentations that feeds the image reconstruction team Design and execute experiment setups for transducer characterization (element sensitivity, bandwidth, cross-talk mapping, beam profile measurements) and ex vivo / phantom clinical testing. Acquire, process, and analyze RF and baseband signals for data quality assessment and benchmarking. Design simple boards and adapters as needed (monitoring, power/safety, interface/conditioning), and take them from prototype through a stable revision. Prototype quickly, then harden what works: wiring/harnessing, grounding, safety interlocks, and reliable integration across subsystems. Own practical test setups and documentation (fixtures, scripts, procedures) that make experiments repeatable and results comparable over time. What we’re looking for Strong hands-on EE background with experience building, debugging, and iterating on real systems in the lab. Solid understanding of signal processing fundamentals — knows what to measure, how to condition and digitize it, and how to evaluate signal quality in the context of an imaging system (SNR, bandwidth, dynamic range, artifacts). Comfortable spanning system integration + occasional design work (schematics/layout reviews or light PCB design) in a fast-moving environment. Ability to work at the boundary between hardware and algorithms: measure reality, communicate constraints, and help close gaps vs simulation. High agency and practicality: able to set up experiments, get trustworthy data, and unblock others on a lean team. Useful experience Analog/mixed-signal, or high-speed data capture experience; strong instincts for instrumentation and noise/debugging. Ultrasound or acoustic sensor handling: hydrophone calibration and field mapping, transducer impedance characterization, element-level sensitivity

GitAIGoRust
D
📍 New York, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.5%

From $1.9M/yr

Quick readStrong listing-quality and freshness signals

Role Overview We’re looking for a Senior Product Designer with a passion for building platform features that impact UX at a massive scale. As a member of AAA, you’ll work across a breadth of problem spaces on deeply technical topics, such as governance, access, teams, identity, and multi-org UX. You’ll lead design for features that mediate how Datadog’s biggest customers use the platform and manage what their employees can see and do. At Datadog, we place value in our office culture - the relationships and collaboration it builds and the creativity it brings to the table. We operate as a hybrid workplace to ensure our Datadogs can create a work-life harmony that best fits them. What You'll Do AAA is a highly technical product environment, where designers strive to understand the technical workflows, constraints and opportunities within this domain. As you develop subject matter expertise, you’ll use your influence as a Senior designer to drive the roadmap and vision. Day-to-day, you’ll work closely with your PM and engineering partners to understand customers’ pain points, explore solutions, and build UI that ships. Prototyping in code creates the opportunity to share high-fidelity ideas at early stages, even if the design itself is low-fidelity. Tight feedback loops let your team iterate quickly, building towards an ideal vision for the best possible experience while you ship incremental steps towards that goal. In addition to making the work, you will also share your work with stakeholders at varying levels of seniority, all the way up to executive leadership level. Your crisp context setting and clear description of your solution will help people understand your choices and sell them on your proposal. Your work will up-level the quality bar for what an admin experience can look like. While you’ll leverage Datadog’s design system where it makes sense, you won’t let it prevent broad exploration of different design patterns in the service of finding the optimal solu

GitAIGoRust
N
📍 Santa Clara, United States
✓ Quality checkedCompany trend -13.7%

NVIDIA has been transforming computer graphics, PC gaming, and accelerated computing for more than 25 years. It’s a unique legacy of innovation that’s fueled by great technology—and amazing people. Today, we’re tapping into the unlimited potential of AI to define the next era of computing. An era in which the GPU acts as the brains of computers, robots, and self-driving cars that can understand the world. Doing what’s never been done before takes vision, innovation, and the world’s best talent. As a Developer Technology Engineer you will be at the forefront of innovation, working with leading industry partners and exciting OSS projects to accelerate RTX & DGX SoC performance for agentic use. This role offers an outstanding opportunity to collaborate with world-class talent and make a significant contribution to the next era of enterprise and consumer AI. What you'll be doing: Own key engagements with our fast-paced developer ecosystem partners, optimizing their applications to deliver outstanding end-to-end performance on RTX and DGX SoCs. Take ownership of performance optimization for compute-intensive CPU, AI, and 3D graphics workloads, working with domain experts to identify bottlenecks and implement effective solutions. Work across system software, GPU driver, architecture, and NVIDIA Research teams to influence next-generation, high-performance SoC platforms by bringing real-world workflows and actionable insights from partner and customer needs. Provide technical guidance and mentorship to junior engineers while contributing to an inclusive and high-performing team environment. What we need to see: BS or MS degree in Computer Science, Engineering, Mathematics or related degree (or equivalent experience) 5+ years of respective work experience as software developer Proficiency in C/C++, Python, software

PythonLinuxAI
I
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -92.5%

From $207K/yr

Quick readStrong listing-quality and freshness signals

We're transforming the grocery industry At Instacart, we invite the world to share love through food because we believe everyone should have access to the food they love and more time to enjoy it together. Where others see a simple need for grocery delivery, we see exciting complexity and endless opportunity to serve the varied needs of our community. We work to deliver an essential service that customers rely on to get their groceries and household goods, while also offering safe and flexible earnings opportunities to Instacart Personal Shoppers. Instacart has become a lifeline for millions of people, and we’re building the team to help push our shopping cart forward. If you’re ready to do the best work of your life, come join our table. Instacart is a Flex First team There’s no one-size fits all approach to how we do our best work. Our employees have the flexibility to choose where they do their best work—whether it’s from home, an office, or your favorite coffee shop—while staying connected and building community through regular in-person events. Learn more about our flexible approach to where we work. Overview: We are looking for a Senior Machine Learning Engineer with a strong Operations Research background to join the Service Availability & Routing team within Instacart's Logistics organization. In this role, you will work at the intersection of combinatorial optimization, mathematical programming, and AI to solve high-impact problems in the fulfillment space — including order batching, shopper routing, service availability prediction, and real-time assignment. You'll partner closely with engineering, product, and data science to ship models and algorithms that directly influence Instacart's profitability and shopper experience at scale. The Logistics & ML group is responsible for the intelligence and execution behind Instacart’s fulfillment system. The team optimizes a multi-sided marketplace to ensure customers get their orders on-time and in high qu

PythonSQLMachine LearningAI
O
📍 Atlanta, Georgia, United States
✓ High-confidence listing
Quick readStrong listing-quality and freshness signals

Strength in Trust OneTrust’s mission is to enable innovation through the responsible use of data and AI. We believe that ensuring data is trusted shouldn’t slow teams down—it should accelerate what’s possible. This led us to develop the first technology platform for responsible data use in 2016. Today, with AI representing the latest and most impactful expansion of data yet, OneTrust is once again redefining what responsible innovation looks like. OneTrust, the AI‑Ready Governance Platform™, unifies regulatory intelligence, automation, and connected governance workflows so businesses can continue to move at the speed of AI while ensuring good governance to prevent data misuse at scale. Trusted by thousands of organizations worldwide, OneTrust is shaping the future where trusted data becomes a transformative force for business and society. The Challenge We're looking for a Senior Software Engineer who will report to the Development Manager / R&D Head. In this role, you will be part of the R&D Team that works on mission-critical applications. Your Mission Contribute to all phases of the development lifecycle. Write well-designed, testable, efficient code Ensure designs are in compliance with specifications Own your code in production, responding to incidents as they occur and participating in retros to determine how to be better in the future Prepare and produce releases of software components Own and triage production incidents with speed Support continuous improvement by investigating alternatives and technologies and presenting these for architectural review You Are/Have BE/BTech/MS degree in Computer Science Engineering or in a related subject. Experience in software application development using Java, Spring Boot, Kafka and Hibernate. Strong knowledge of algorithms, data structures, and system design patterns. Experience with SQL and NoSQL

JavaSQLLinuxAI
A
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -99%

From $196K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Airbnb’s mission is to create a world where anyone can belong anywhere. Airbnb Payments team supports this mission by economically empowering Airbnb businesses and our global community of guests and hosts. Airbnb Payments team allows any two people in the world to frictionlessly exchange money with easy to use payments services. It is a core strategy to fulfill Airbnb’s belongs anywhere mission. We are building a world-class payments platform that moves billions of dollars, in 191 countries, with 75 currencies, through a complex ecosystem of payments partners. We build and maintain our own in-house global payments platform because no solution exists with the global reach needed. The Ledger team is part of the core platform of the Airbnb Payments ecosystem, where we own the financial integrity of Airbnb's money movement. The team is building Airbnb's financial system of record and the platform that governs when money is held rather than moved. The team engineers are responsible for ensuring that every payment event is recorded accurately and completely, and that money moves — or is held — exactly as Airbnb's obligations and controls require, in a way that is reliable, accurate, timely, scalable, and auditable. We are evolving these platforms to enable the next generation of Airbnb payments products, and the engineers who join us will help set the foundations those products are built on. The Difference You Will Make: We are looking for talented and self-motivated Senior Software Engineers who are passionate about working in this highly dynamic domain and collaborating with world

ReactAIGoExcel
B
📍 Round Lake, Illinois, United States
✓ Quality checkedCompany trend +320%

This is where your work makes a difference. At Baxter, we believe every person—regardless of who they are or where they are from—deserves a chance to live a healthy life. It was our founding belief in 1931 and continues to be our guiding principle. We are redefining healthcare delivery to make a greater impact today, tomorrow, and beyond. Our Baxter colleagues are united by our Mission to Save and Sustain Lives. Together, our community is driven by a culture of courage, trust, and collaboration. Every individual is empowered to take ownership and make a meaningful impact. We strive for efficient and effective operations, and we hold each other accountable for delivering exceptional results. Here, you will find more than just a job—you will find purpose and pride. Job Description Your Role at Baxter This is where your work saves lives. As Senior Software Engineer, own and direct the cybersecurity design and analysis of multiple medical devices. Demonstrate subject matter expert knowledge in state-of-the-art security principles. Resolve difficult problems, from conception to final design with team input. Plan, lead, and deliver project assignments in the evaluation, selection and adaptation of various cybersecurity engineering techniques, procedures, and criteria with minimal guidance. Contributes to a cybersecurity vision that aligns with the organization's vision and strategic plan. Utilizes solid understanding of device and system connectivity concepts in a medical device domain. Provides direction to technical team members that are accountable for implementing cybersecurity, integration, and connectivity deliverables. Exhibits creativity and innovation in completing divisional and cross-functional/business unit goals and objectives. What you&#

Recruitment
A
📍 United States· Full-time· Remote
✓ High-confidence listingCompany trend -99%

From $248K/yr

Quick readStrong listing-quality and freshness signals

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Our mission at Marketing Technology is to provide a state-of-the-art platform and measurement capabilities to enable marketing and product teams to engage with our customers effectively. Every day, millions of Airbnb customers are reached via our streamlined platform over comprehensive marketing channels such as Email, Push, SMS, Google Ads, Facebook Ads etc. We deliver substantial business impact by enabling numerous stakeholders across the company, including Marketing (Brand and Performance), Guest, Host, Airbnb Org, Policy, and more. The Difference You Will Make: As a Senior Staff Software Engineer on the Content Platform team, you'll set the technical direction for the org's transformation into an AI-driven system that turns a marketing brief into a fully realized campaign in minutes, not months. You'll own the technical strategy across a complex, multi-team surface area spanning a CMS platform, no-code authoring tools, rendering infrastructure, and an emerging agentic layer, all operating at a scale where the content produced is consumed by millions of Airbnb users daily. You will partner with engineering leadership, product, design, and marketing stakeholders across the company to define multi-year technical strategy, resolve the org's hardest cross-team technical challenges, and raise the bar for engineering excellence across Marketing Technology. A Typical Day: As a Senior Staff Software Engineer on Content Platform, you will: Define and drive technical vision and strategy for the Content Platform org, ensuring architectural decisions scale across teams and ali

JavaSQLRedisGraphql
A
📍 United States· Full-time· Remote
✓ Quality checkedCompany trend -99%

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Airbnb’s mission is to create a world where anyone can belong anywhere. Airbnb Payments team supports this mission by economically empowering Airbnb businesses and our global community of guests and hosts. Airbnb Payments team allows any two people in the world to frictionlessly exchange money with easy to use payments services. It is a core strategy to fulfill Airbnb’s belongs anywhere mission.We are building a world-class payments platform that moves billions of dollars, in 191 countries, with 75 currencies, through a complex ecosystem of payments partners. We build and maintain our own in-house global payments platform because no solution exists with the global reach needed. As the platform grows we’ll be adding new payment partners, global licenses, compliance and regulation controls, and building new payment experiences for our guests and hosts. Payments Transactions team and Payments Payouts team are part of the core platform of the Airbnb Payments ecosystem. The teams are building the core billing system and payouts system for Airbnb money movements. The team engineers are responsible for the seamless orchestration and recording of Airbnb’s payment obligations with our community. They initiate, advance, and realize Airbnb’s payment commitments with our community in a way that is reliable, accurate, timely, scalable, and auditable. The Difference You Will Make: We are looking for talented and self-motivated Senior Software Engineers who are passionate about working in this highly dynamic domain and collaborating with world-class XFN teams to advance our mission. As part

D
📍 Georgia, New York, United States· Full-time
✓ High-confidence listingCompany trend -88.5%

From $244K/yr

Quick readStrong listing-quality and freshness signals

The Language Tools team enables ~1,500 Datadog developers to build, test, and package millions of lines of Go, Python, Java, Rust, and TypeScript in our backend monorepo. Our success is measured by their productivity and satisfaction. They use the tools that we develop and support several times a day, in both development and CI environments. We use the Bazel open source build system as a foundation. The team is growing rapidly, both with Datadog and as we absorb other repositories into the monorepo. As a senior software engineer on the team, you will own projects from start to finish, both greenfield and brownfield. You will gain first-hand understanding of what Datadog developers need, and inform our roadmap. At Datadog, we place value in our office culture - the relationships that it builds, the creativity it brings to the table, and the collaboration of being together. We operate as a hybrid workplace to ensure our employees can create a work-life harmony that best fits them. What You’ll Do: Invent build, test and packaging tools that are simpler and more reliable to use. Push performance and cost efficiency at scale, raising cache hit rates and cutting CI times and compute spend across millions of targets. Treat CI like SREs treat prod, making sure our pipelines are green and fast. Prepare, run, and finish complex migrations. Contribute back to the Bazel ecosystem, upstreaming fixes and shaping features we depend on. Who You Are: An expert in Bazel and/or one of the languages listed above. A well-rounded engineer. You must broadly understand the various types of software projects that are built, tested, and packaged with our tools. Both careful and fearless. The changes we make impact the velocity of hundreds of engineers. They are risky but necessary. User-focused. We help Datadog engineers to use the tools that we develop, and continuously improve their usability, so they don’t need our help the next time. Ideally, you have ex

TypeScriptPythonJavaAI
C
📍 United States· Full-time· Remote
✓ Quality checkedCompany trend -100%

Ready to do the most impactful work of your career? At Coinbase , we are uncompromising on our mission to increase economic freedom. The bar is high, the environment is intense, and we like it that way. This isn't a place for complacency, it’s a place to be pushed past your perceived limits. If you're ready to build the future of finance alongside people who refuse to settle for "good enough," you belong here. Coinbase is a remote-first, but not remote-only company. Expect to get together quarterly for intense in-person working sessions called “surges.” learn more about working at Coinbase . Senior Software Engineer, Frontend (Coinbase Advisor - Agentic Trading) We're hiring a Senior Software Engineer to join the Coinbase Advisor team within the Consumer & Business group. Coinbase Advisor is the world's first RIA-licensed agentic trading system: an AI advisor living inside the Coinbase app that holds a natural conversation about a user's portfolio, gives personalized financial advice, and executes trades on their behalf. This role is primarily frontend on a full-stack team. You'll own the interfaces that make agentic trading feel fast, clear, and trustworthy for millions of customers, and you'll follow that work into our Go services and LLM layer when the product calls for it. What you'll do: &

TypeScriptReactAWSAI
M
📍 Minnesota, United States of America, United States
✓ Quality checkedCompany trend +5.4%

We anticipate the application window for this opening will close on - 30 Sep 2026 Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact. A Day in the Life Our Automation Platforms team develops and scales reusable technologies that improve safety, quality, and productivity across Medtronic’s global manufacturing network. We're working onsite 4 days a week as part of our commitment to fostering a culture of professional growth and cross-functional collaboration as we work together to engineer the extraordinary. The person in this role will work from the Medtronic facility located in Fridley, Minnesota. This role will require 25% of travel to enhance collaboration and ensure successful completion of projects. The Sr Principal Robotics & AMR Automation Platforms Engineer will serve as the enterprise technical authority for autonomous mobile robotics, collaborative robotics, and emerging intelligent automation technologies, advancing reusable platforms from technology development through factory validation and global deployment. This role will define technical strategy, platform architectures, roadmaps, standards, and reusable capabilities while partnering with manufacturing sites, engineering teams, IT/OT, suppliers, system integrators, and Medtronic’s Surgical Robotics organization. The successful can

AIRecruitmentHR
🔔

Get new senior it systems engineer jobs in United States by email

Daily job updates · Unsubscribe anytime